NeuroMMSig 2.0.0

Provenance information is extracted from the header in the source BEL document.

Authors: None
Contact: daniel.domingo.fernandez@scai.fraunhofer.de
Copyright: Copyright © 2019 Fraunhofer SCAI, All rights reserved.

Summary

Number of Nodes: 2003
Number of Edges: 6829
Number of Citations: 1035
Number of Authors: 0
Network Density: 1.70E-03
Number of Components: 14
Number of Warnings: 0

Nodes

Each node in a BEL graph is assigned a type. Most nodes are then identified with a namespace:identifier pair, or a definition based on other nodes as in the case of complexes, composites, and chemical reactions.

Edges

Topology

Bibliometrics

Statements

Reference	BEL
pmid:8584603	a(CHEBI:"(R)-adrenaline") increases bp(GOBP:"neuron-neuron synaptic transmission")
pmid:8584603	a(CHEBI:"(R)-adrenaline") increases bp(GOBP:cognition)
pmid:20170836	a(CHEBI:"EC 3.1.1.7 (acetylcholinesterase) inhibitor") increases bp(GOBP:cognition)
pmid:22434822	a(CHEBI:"amyloid-beta") positiveCorrelation deg(p(HGNC:CLSTN1))
pmid:22212405	a(CHEBI:"amyloid-beta") association bp(GOBP:"axonal transport")
pmid:22434822	a(CHEBI:"amyloid-beta") association bp(GOBP:"axonal transport")
pmid:15232608	a(CHEBI:"amyloid-beta") increases act(p(HGNC:CASP4))
pmid:15232608	a(CHEBI:"amyloid-beta") association a(MESH:D017628)
pmid:20205643	a(CHEBI:"amyloid-beta") association a(MESH:D017628)
pmid:15232608	a(CHEBI:"amyloid-beta") increases a(CHEBI:"reactive oxygen species")
pmid:22523685	a(CHEBI:"amyloid-beta") increases a(CHEBI:"reactive oxygen species")
pmid:19245828	a(CHEBI:"amyloid-beta") increases a(CHEBI:"reactive oxygen species")
pmid:15232608	a(CHEBI:"amyloid-beta") increases path(MESHD:"Neurogenic Inflammation")
pmid:15232608	a(CHEBI:"amyloid-beta") increases a(CHEBI:"nitric oxide")
pmid:15232608	a(CHEBI:"amyloid-beta") increases p(HGNC:TNF)
pmid:15232608	a(CHEBI:"amyloid-beta") increases p(HGNC:IL1B)
pmid:21295112	a(CHEBI:"amyloid-beta") increases act(p(HGNC:IL1B))
pmid:18021299	a(CHEBI:"amyloid-beta") positiveCorrelation p(HGNC:IL1B)
pmid:18782350	a(CHEBI:"amyloid-beta") increases act(complex(SCOMP:"Calcineurin Complex"))
pmid:19782073	a(CHEBI:"amyloid-beta") increases act(p(SFAM:"GSK3 Family"))
pmid:19038340	a(CHEBI:"amyloid-beta") increases act(p(SFAM:"GSK3 Family"))
pmid:10662829	a(CHEBI:"amyloid-beta") increases act(p(HGNC:CASP2), ma(pep))
pmid:1346802	a(CHEBI:"amyloid-beta") association p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")
pmid:21244351	a(CHEBI:"amyloid-beta") association act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits"))
pmid:1346802	a(CHEBI:"amyloid-beta") association bp(GOBP:"regulation of kainate selective glutamate receptor activity")
pmid:1346802	a(CHEBI:"amyloid-beta") increases tloc(a(CHEBI:"calcium(2+)"), fromLoc(GOCC:"extracellular space"), toLoc(GOCC:"intracellular part"))
pmid:18675468	a(CHEBI:"amyloid-beta") directlyIncreases tloc(a(CHEBI:"calcium(2+)"), fromLoc(MESHCS:"Extracellular Space"), toLoc(MESHCS:Cytoplasm))
pmid:20847424	a(CHEBI:"amyloid-beta") increases a(CHEBI:"calcium(2+)")
pmid:12607822	a(CHEBI:"amyloid-beta") decreases act(p(HGNC:CKB), ma(kin))
pmid:20178983	a(CHEBI:"amyloid-beta") increases act(p(HGNC:MTOR))
pmid:21755121	a(CHEBI:"amyloid-beta") positiveCorrelation p(HGNC:CXCL8)
pmid:21755121	a(CHEBI:"amyloid-beta") positiveCorrelation p(HGNC:CXCL10)
pmid:22523685	a(CHEBI:"amyloid-beta") decreases bp(GOBP:"electron transport chain")
pmid:22523685	a(CHEBI:"amyloid-beta") decreases bp(GOBP:"electron transport chain")
pmid:22523685	a(CHEBI:"amyloid-beta") decreases bp(GOBP:"mitochondrion organization")
pmid:22523685	a(CHEBI:"amyloid-beta") decreases bp(GOBP:"mitochondrial transport")
pmid:22523685	a(CHEBI:"amyloid-beta") decreases bp(GOBP:"mitochondrial calcium ion homeostasis")
pmid:22523685	a(CHEBI:"amyloid-beta") decreases a(CHEBI:ATP)
pmid:22523685	a(CHEBI:"amyloid-beta") decreases bp(GOBP:"mitochondria-nucleus signaling pathway")
pmid:22523685	a(CHEBI:"amyloid-beta") increases bp(GOBP:"apoptotic process")
pmid:22178568	a(CHEBI:"amyloid-beta") positiveCorrelation bp(GOBP:"apoptotic process")
pmid:22178568	a(CHEBI:"amyloid-beta") increases bp(GOBP:"apoptotic process")
pmid:22514144	tloc(a(CHEBI:"amyloid-beta"), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space")) association p(HGNC:APP, var("p.Lys687Asn"))
pmid:19519303	a(CHEBI:"amyloid-beta") association act(p(SFAM:"MAPK Erk1/2 Family"))
pmid:22496686	a(CHEBI:"amyloid-beta") association p(HGNC:APOE)
pmid:16195918	a(CHEBI:"amyloid-beta") association p(HGNC:APOE)
pmid:22496686	a(CHEBI:"amyloid-beta") decreases act(p(HGNC:RELN))
pmid:22496686	a(CHEBI:"amyloid-beta") decreases bp(GOBP:"reelin-mediated signaling pathway")
pmid:22496686	a(CHEBI:"amyloid-beta") decreases p(HGNC:GRIN2A, pmod(Ph))
pmid:22496686	a(CHEBI:"amyloid-beta") decreases p(HGNC:GRIN2B, pmod(Ph))
pmid:22453989	a(CHEBI:"amyloid-beta") association bp(GOBP:"calcium ion homeostasis")
pmid:18675468	a(CHEBI:"amyloid-beta") decreases bp(GOBP:"calcium ion homeostasis")
Online Resource:hsa05010	a(CHEBI:"amyloid-beta") decreases bp(GOBP:"calcium ion homeostasis")
pmid:22453989	a(CHEBI:"amyloid-beta") association bp(GOBP:"negative regulation of calcium-mediated signaling")
pmid:22382662	a(CHEBI:"amyloid-beta") increases p(HGNC:MAPT, pmod(Ph))
Online Resource:hsa05010	a(CHEBI:"amyloid-beta") increases p(HGNC:MAPT, pmod(Ph))
pmid:12402041	a(CHEBI:"amyloid-beta") association p(HGNC:MAPT, pmod(Ph))
pmid:19038340	a(CHEBI:"amyloid-beta") positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:22382662	a(CHEBI:"amyloid-beta") positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:19394434	a(CHEBI:"amyloid-beta") increases path(MESHD:"Alzheimer Disease")
pmid:20675880	a(CHEBI:"amyloid-beta") increases path(MESHD:"Alzheimer Disease")
pmid:22047170	a(CHEBI:"amyloid-beta") increases path(MESHD:"Alzheimer Disease")
pmid:16687508	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:20385830	a(CHEBI:"amyloid-beta") increases path(MESHD:"Alzheimer Disease")
pmid:21785276	a(CHEBI:"amyloid-beta") increases path(MESHD:"Alzheimer Disease")
pmid:23556446	a(CHEBI:"amyloid-beta") increases path(MESHD:"Alzheimer Disease")
pmid:15331417	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:17495608	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:17185504	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:15218540	a(CHEBI:"amyloid-beta") increases path(MESHD:"Alzheimer Disease")
pmid:16027115	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:17205046	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:17360493	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:19199126	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:19355846	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:19462468	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:19698775	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:20138836	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:20157255	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:12473667	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:14622952	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:16306400	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:17541560	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:18813209	a(CHEBI:"amyloid-beta") increases path(MESHD:"Alzheimer Disease")
pmid:8626687	a(CHEBI:"amyloid-beta") association path(MESHD:"Alzheimer Disease")
pmid:22212405	a(CHEBI:"amyloid-beta") decreases act(p(HGNC:NTRK2))
pmid:22212405	a(CHEBI:"amyloid-beta") decreases act(p(HGNC:BDNF))
pmid:21945540	a(CHEBI:"amyloid-beta") increases act(p(HGNC:GSK3B))
pmid:16914869	a(CHEBI:"amyloid-beta") increases act(p(HGNC:GSK3B))
pmid:21945540	a(CHEBI:"amyloid-beta") increases bp(GOBP:"neuron apoptotic process")
pmid:22262751	a(CHEBI:"amyloid-beta") association g(DBSNP:rs6656401)
pmid:19394434	a(CHEBI:"amyloid-beta") decreases bp(GOBP:memory)
pmid:17956317	a(CHEBI:"amyloid-beta") decreases bp(GOBP:memory)
pmid:15084661	a(CHEBI:"amyloid-beta") negativeCorrelation bp(GOBP:memory)
pmid:21156028	a(CHEBI:"amyloid-beta") increases p(HGNC:DYRK1A)
pmid:12668899	a(CHEBI:"amyloid-beta") association a(CHEBI:cholesterol)
pmid:17495608	a(CHEBI:"amyloid-beta") association a(CHEBI:cholesterol)
pmid:17495608	a(CHEBI:"amyloid-beta") association a(CHEBI:cholesterol)
pmid:18308724	a(CHEBI:"amyloid-beta") association a(CHEBI:cholesterol)
pmid:20138836	a(CHEBI:"amyloid-beta") association a(CHEBI:cholesterol)
pmid:18675468	a(CHEBI:"amyloid-beta") decreases bp(GOBP:"sodium ion homeostasis")
pmid:19419557	a(CHEBI:"amyloid-beta") association bp(GOBP:"calcium-mediated signaling")
pmid:17956317	a(CHEBI:"amyloid-beta") increases act(p(SFAM:"MAPK JNK Family"), ma(kin))
pmid:20205643	a(CHEBI:"amyloid-beta") association a(MESH:D055017)
pmid:15910549	a(CHEBI:"amyloid-beta") increases a(CHEBI:"copper(1+)")
pmid:15910549	a(CHEBI:"amyloid-beta") increases a(CHEBI:"copper(0)")
pmid:15910549	a(CHEBI:"amyloid-beta") increases bp(GOBP:"copper ion export")
pmid:20847424	a(CHEBI:"amyloid-beta") association p(HGNC:SLC25A6)
pmid:20847424	a(CHEBI:"amyloid-beta") association p(HGNC:SLC25A4)
pmid:20847424	a(CHEBI:"amyloid-beta") association p(HGNC:SLC25A5)
pmid:20847424	a(CHEBI:"amyloid-beta") association p(HGNC:SLC25A31)
pmid:20847424	a(CHEBI:"amyloid-beta") decreases bp(GOBP:"positive regulation of synaptic plasticity")
pmid:20847424	a(CHEBI:"amyloid-beta") increases bp(GOBP:"positive regulation of synaptic plasticity")
pmid:22455924	a(CHEBI:"amyloid-beta") increases act(p(HGNC:APP))
pmid:19245828	a(CHEBI:"amyloid-beta") positiveCorrelation p(HGNC:APP)
pmid:20385830	a(CHEBI:"amyloid-beta") negativeCorrelation bp(GOBP:"chemical synaptic transmission")
pmid:20385830	a(CHEBI:"amyloid-beta") increases path(MESHD:"Memory Disorders")
pmid:20385830	a(CHEBI:"amyloid-beta") decreases bp(MESHPP:"Long-Term Potentiation")
Online Resource:hsa05010	a(CHEBI:"amyloid-beta") decreases act(a(MESH:D008928))
Online Resource:REACT_75925.2	a(CHEBI:"amyloid-beta") increases path(MESHD:Amyloidosis)
Online Resource:REACT_75925.2	a(CHEBI:"amyloid-beta") association p(HGNC:SNCA)
pmid:19519303	a(CHEBI:"amyloid-beta") association path(MESHD:Hyperinsulinism)
pmid:19519303	a(CHEBI:"amyloid-beta") association bp(GOBP:"regulation of phosphatidylinositol 3-kinase activity")
pmid:19519303	deg(a(CHEBI:"amyloid-beta")) association complex(a(CHEBI:"amyloid-beta"), p(HGNC:LRP1))
pmid:19519303	deg(a(CHEBI:"amyloid-beta")) association bp(GOBP:"maintenance of permeability of blood-brain barrier")
pmid:19519303	deg(a(CHEBI:"amyloid-beta")) association complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE), p(HGNC:LRP1))
pmid:19519303	deg(a(CHEBI:"amyloid-beta")) association complex(a(CHEBI:"amyloid-beta"), p(HGNC:A2M), p(HGNC:LRP1))
pmid:22178568	a(CHEBI:"amyloid-beta") association m(HGNC:"MIR124-1")
pmid:21720722	a(CHEBI:"amyloid-beta") decreases m(HGNC:MIR181C)
pmid:21720722	a(CHEBI:"amyloid-beta") decreases m(HGNC:"MIR9-1")
pmid:20061608	a(CHEBI:"amyloid-beta") biomarkerFor path(MESHD:"Diabetes Mellitus, Type 2")
pmid:11956956	a(CHEBI:"amyloid-beta") association act(p(HGNC:INS))
pmid:11956956	a(CHEBI:"amyloid-beta") negativeCorrelation p(HGNC:INS)
pmid:15094078	a(CHEBI:"amyloid-beta") negativeCorrelation act(p(HGNC:INSR))
pmid:20157512	a(CHEBI:"amyloid-beta") association path(MESHD:Inflammation)
pmid:10222124	a(CHEBI:"amyloid-beta") increases path(MESHD:Inflammation)
pmid:24519975	a(CHEBI:"amyloid-beta") positiveCorrelation act(p(HGNC:MMP9))
pmid:24984171	a(CHEBI:"amyloid-beta") decreases bp(GOBP:cognition)
pmid:11226677	a(CHEBI:"amyloid-beta") increases p(HGNC:BCL2L1)
pmid:11226677	a(CHEBI:"amyloid-beta") increases path(MESHD:"Amyloid Neuropathies")
pmid:12742739	a(CHEBI:"amyloid-beta") increases p(HGNC:FASLG)
pmid:11567045	a(CHEBI:"amyloid-beta") increases bp(GOBP:"cell death")
pmid:11640947	a(CHEBI:"amyloid-beta", loc(MESHCS:Cytoplasm)) increases p(HGNC:E2F1)
pmid:10560656	a(CHEBI:"amyloid-beta") positiveCorrelation p(HGNC:PTGS1)
pmid:11194936	a(CHEBI:"amyloid-beta") positiveCorrelation p(HGNC:PTGS1)
pmid:23558999	a(CHEBI:"amyloid-beta") increases p(HGNC:DDIT3)
pmid:23558999	a(CHEBI:"amyloid-beta") causesNoChange p(HGNC:HSPA5)
pmid:16532272	a(CHEBI:"amyloid-beta") increases act(p(HGNC:EIF2AK2))
pmid:12754271	a(CHEBI:"amyloid-beta") increases p(HGNC:PLAU)
pmid:12754271	a(CHEBI:"amyloid-beta") increases p(HGNC:PLAUR)
pmid:18688088	a(CHEBI:"amyloid-beta") increases act(p(HGNC:RPS6KB1))
pmid:21280074	a(CHEBI:"amyloid-beta") association p(HGNC:ALOX5)
pmid:17424907	a(CHEBI:"amyloid-beta") association act(a(MESHCS:Mitochondria))
pmid:15882940	a(CHEBI:"amyloid-beta") increases p(HGNC:CSF1)
pmid:15882940	a(CHEBI:"amyloid-beta") increases p(HGNC:CSF1)
pmid:11523796	a(CHEBI:"amyloid-beta") association complex(p(HGNC:APOE), p(HGNC:APP))
pmid:9265639	a(CHEBI:"amyloid-beta") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE))
pmid:17255335	a(CHEBI:"amyloid-beta") increases p(HGNC:IFNG)
pmid:20157255	a(CHEBI:"amyloid-beta") association p(HGNC:LEP)
pmid:20451519	a(CHEBI:"amyloid-beta") increases p(HGNC:BACE1)
pmid:20595388	a(CHEBI:"amyloid-beta") increases p(HGNC:BACE1)
pmid:20595388	a(CHEBI:"amyloid-beta") increases p(HGNC:BACE1)
pmid:14530380	a(CHEBI:"amyloid-beta") association complex(a(CHEBI:"heparan sulfate"), p(HGNC:BACE1))
pmid:12402041	a(CHEBI:"amyloid-beta") increases complex(p(HGNC:CD40), p(HGNC:CD40LG))
pmid:21389115	a(CHEBI:"amyloid-beta") association act(p(HGNC:CDK5), ma(kin))
pmid:10993067	a(CHEBI:"amyloid-beta") association p(HGNC:NCSTN)
pmid:16423463	a(CHEBI:"amyloid-beta") association p(HGNC:NCSTN)
pmid:19394408	a(CHEBI:"amyloid-beta") association p(HGNC:NCSTN)
pmid:19038340	a(CHEBI:"amyloid-beta") increases p(HGNC:CASP3)
pmid:19038340	a(CHEBI:"amyloid-beta") increases p(HGNC:MAPK8IP1)
pmid:17251431	a(CHEBI:"amyloid-beta") increases p(HGNC:BCL2L11)
pmid:17251431	a(CHEBI:"amyloid-beta") association p(HGNC:BCL2L11)
pmid:17385278	a(CHEBI:"amyloid-beta") association p(HGNC:NGFR)
pmid:16930450	a(CHEBI:"amyloid-beta") association p(HGNC:SORL1)
pmid:19035514	a(CHEBI:"amyloid-beta") increases act(p(HGNC:CASR))
pmid:20847424	a(CHEBI:"amyloid-beta") increases bp(GOBP:"regulation of neuronal synaptic plasticity")
pmid:20847424	a(CHEBI:"amyloid-beta") decreases bp(GOBP:"regulation of synaptic activity")
pmid:20847424	a(CHEBI:"amyloid-beta") decreases a(CHEBI:"glutamate(2-)")
pmid:20847424	a(CHEBI:"amyloid-beta") increases bp(GOBP:neurogenesis)
pmid:20847424	a(CHEBI:"amyloid-beta") decreases p(HGNC:GRIA1)
pmid:20847424	a(CHEBI:"amyloid-beta") decreases p(HGNC:GRIA2)
pmid:20847424	a(CHEBI:"amyloid-beta") decreases p(HGNC:GRIA3)
pmid:20847424	a(CHEBI:"amyloid-beta") decreases p(HGNC:GRIA4)
pmid:20847424	a(CHEBI:"amyloid-beta") decreases p(HGNC:GRIN2A)
pmid:20847424	a(CHEBI:"amyloid-beta") decreases p(HGNC:GRIN2B)
pmid:20847424	a(CHEBI:"amyloid-beta") decreases p(HGNC:GRIN2C)
pmid:20847424	a(CHEBI:"amyloid-beta") decreases p(HGNC:GRIN2D)
pmid:20847424	a(CHEBI:"amyloid-beta") decreases p(HGNC:GRIN3A)
pmid:20847424	a(CHEBI:"amyloid-beta") decreases p(HGNC:GRIN3B)
pmid:20847424	a(CHEBI:"amyloid-beta") association bp(GOBP:"neuron cellular homeostasis")
pmid:20847424	a(CHEBI:"amyloid-beta") increases bp(GOBP:"brain development")
pmid:20847424	a(CHEBI:"amyloid-beta") increases bp(GOBP:"negative regulation of neuron apoptotic process")
pmid:20847424	a(CHEBI:"amyloid-beta") association p(HGNC:CACNG1)
pmid:20847424	a(CHEBI:"amyloid-beta") association p(HGNC:CACNG2)
pmid:20847424	a(CHEBI:"amyloid-beta") association p(HGNC:CACNG3)
pmid:20847424	a(CHEBI:"amyloid-beta") association p(HGNC:CACNG4)
pmid:20847424	a(CHEBI:"amyloid-beta") association p(HGNC:CACNG5)
pmid:20847424	a(CHEBI:"amyloid-beta") association p(HGNC:CACNG6)
pmid:20847424	a(CHEBI:"amyloid-beta") association p(HGNC:CACNG7)
pmid:20847424	a(CHEBI:"amyloid-beta") association p(HGNC:CACNG8)
pmid:18650430	a(CHEBI:"amyloid-beta") increases bp(GOBP:"cell adhesion")
pmid:24369524	a(CHEBI:"amyloid-beta") association bp(GOBP:"microglial cell activation")
pmid:23040664	a(CHEBI:"amyloid-beta") increases bp(GOBP:"microglial cell activation")
pmid:8287928	a(CHEBI:"amyloid-beta") increases path(MESHD:Gliosis)
pmid:15673661	a(CHEBI:"amyloid-beta") positiveCorrelation p(MGI:App)
pmid:21725719	a(CHEBI:"amyloid-beta") positiveCorrelation p(MGI:Bace1)
pmid:20092570	a(CHEBI:"amyloid-beta") positiveCorrelation p(MGI:Bace1)
pmid:26027813	a(CHEBI:"amyloid-beta") association a(NIFT:"Cortical Thickness")
pmid:16887805	a(CHEBI:"amyloid-beta") increases bp(GOBP:"neuron death")
pmid:23164821	a(CHEBI:"amyloid-beta") increases p(HGNC:DKK1)
pmid:23164821	a(CHEBI:"amyloid-beta") increases p(HGNC:CLU, loc(GOCC:intracellular))
pmid:23164821	a(CHEBI:"amyloid-beta") decreases tloc(p(HGNC:CLU), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:23792694	a(CHEBI:"amyloid-beta") increases p(SFAM:"MMP Family")
pmid:23792694	a(CHEBI:"amyloid-beta") increases p(HGNC:TIMP1)
pmid:23792694	a(CHEBI:"amyloid-beta") increases tloc(p(HGNC:TIMP1), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:15817521	a(CHEBI:"amyloid-beta") increases bp(GOBP:"chronic inflammatory response")
pmid:10222124	a(CHEBI:"amyloid-beta") increases bp(GOBP:"leukotriene production involved in inflammatory response")
pmid:10222124	a(CHEBI:"amyloid-beta") increases bp(GOBP:"inflammatory response")
pmid:21143158	a(CHEBI:"amyloid-beta") increases bp(GOBP:"inflammatory response")
pmid:19388207	a(CHEBI:"amyloid-beta") increases act(p(HGNC:TLR2))
pmid:19388207	a(CHEBI:"amyloid-beta") increases act(p(HGNC:TLR4))
pmid:19388207	a(CHEBI:"amyloid-beta") increases act(p(HGNC:NOD2))
pmid:19388207	a(CHEBI:"amyloid-beta") increases act(p(HGNC:FPR1))
pmid:19388207	a(CHEBI:"amyloid-beta") increases act(p(HGNC:FPR2))
pmid:19388207	a(CHEBI:"amyloid-beta") increases act(p(HGNC:AGER))
pmid:19388207	a(CHEBI:"amyloid-beta") increases act(p(HGNC:MSR1))
pmid:19388207	a(CHEBI:"amyloid-beta") increases act(p(HGNC:SCARB1))
pmid:19388207	a(CHEBI:"amyloid-beta") increases act(p(HGNC:PTX3))
pmid:20049331	a(CHEBI:"amyloid-beta") association act(a(GOCC:microtubule))
pmid:15772078	a(CHEBI:"amyloid-beta") association p(HGNC:LRP1)
pmid:26996954	a(CHEBI:"amyloid-beta") positiveCorrelation a(NIFT:"Grey matter atrophy")
pmid:21244351	a(CHEBI:"amyloid-beta") increases bp(GOBP:"glutamate secretion")
pmid:21244351	a(CHEBI:"amyloid-beta") increases a(CHEBI:"D-serine")
pmid:22227962	a(CHEBI:"amyloid-beta") positiveCorrelation p(HGNC:NOS2)
pmid:22227962	deg(a(CHEBI:"amyloid-beta")) negativeCorrelation p(HGNC:NOS2)
pmid:20205643	a(CHEBI:"amyloid-beta") negativeCorrelation complex(p(HGNC:CCL2), p(HGNC:CCR2))
pmid:19885299	tloc(a(CHEBI:"amyloid-beta"), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space")) positiveCorrelation bp(GOBP:"hydrogen peroxide-mediated programmed cell death")
pmid:21881209	a(CHEBI:"amyloid-beta") negativeCorrelation p(MGI:Abcc1)
pmid:20847424	a(CHEBI:"calcium(2+)") increases bp(GOBP:"regulation of short-term neuronal synaptic plasticity")
pmid:21253550	a(CHEBI:"calcium(2+)") increases act(complex(SCOMP:"gamma Secretase Complex"), ma(pep))
pmid:18675468	a(CHEBI:"calcium(2+)") increases tloc(a(CHEBI:"phosphatidyl-L-serine"), fromLoc(MESHCS:"Cell Membrane"), toLoc(MESHCS:"Cell Surface Extensions"))
pmid:18675468	a(CHEBI:"calcium(2+)") directlyIncreases act(p(HGNC:PLSCR1))
pmid:20847424	a(CHEBI:"calcium(2+)") decreases bp(GOBP:"positive regulation of synaptic plasticity")
pmid:20847424	a(CHEBI:"calcium(2+)") increases bp(GOBP:"negative regulation of neuron apoptotic process")
pmid:21544200	a(CHEBI:"calcium(2+)") increases a(CHEBI:"reactive oxygen species")
pmid:8584603	a(CHEBI:"cholinergic agonist") increases act(complex(a(MESH:D007031), a(MESH:D010902)))
pmid:19549813	a(CHEBI:"copper(II) sulfate pentahydrate") decreases r(HGNC:CHRNB1)
pmid:19549813	a(CHEBI:"copper(II) sulfate pentahydrate") decreases r(HGNC:AIFM1)
pmid:19549813	a(CHEBI:"copper(II) sulfate pentahydrate") increases r(HGNC:GABRA5)
pmid:19549813	a(CHEBI:"copper(II) sulfate pentahydrate") decreases r(HGNC:GABRB3)
pmid:12633900	a(CHEBI:"cyclosporin A") decreases act(p(HGNC:ACHE))
pmid:20106945	a(CHEBI:"cyclosporin A") decreases r(HGNC:BCHE)
pmid:21490080	a(CHEBI:"cyclosporin A") decreases p(MGI:Cycs)
pmid:21490080	a(CHEBI:"cyclosporin A") increases p(MGI:Bcl2)
pmid:21490080	a(CHEBI:"cyclosporin A") decreases p(MGI:Bax)
pmid:21490080	a(CHEBI:"cyclosporin A") decreases bp(GOBP:"apoptotic process")
pmid:16316932	a(CHEBI:"cyclosporin A") increases act(p(SFAM:"AKT Family"))
pmid:20938992	a(CHEBI:"folic acid") negativeCorrelation p(MGI:Chrnb1)
pmid:15211800	a(CHEBI:"folic acid") increases r(HGNC:BIRC2)
pmid:18718604	a(CHEBI:"glutamate(2-)") increases p(RGD:Tnf)
pmid:17015226	a(CHEBI:"glutamate(2-)") increases a(CHEBI:"calcium(2+)")
pmid:17213958	a(CHEBI:"hydrogen peroxide") directlyIncreases act(p(HGNC:ACHE), ma(pep))
pmid:17213958	a(CHEBI:"hydrogen peroxide") negativeCorrelation act(p(HGNC:ACHE), ma(pep))
pmid:15864339	a(CHEBI:"hydrogen peroxide") increases a(CHEBI:"amyloid-beta")
pmid:18997293	a(CHEBI:"hydrogen peroxide") increases bp(GOBP:"neuron apoptotic process")
pmid:17213958	a(CHEBI:"hydrogen peroxide") increases bp(GOBP:"neuron apoptotic process")
pmid:23653222	a(CHEBI:"hydrogen peroxide") increases bp(GOBP:"neuron apoptotic process")
pmid:17869087	a(CHEBI:"hydrogen peroxide") increases bp(GOBP:"apoptotic process")
pmid:21179406	a(CHEBI:"hydrogen peroxide") association p(HGNC:AIFM1)
pmid:15864339	a(CHEBI:"hydrogen peroxide") directlyIncreases a(CHEBI:isoprostane)
pmid:17213958	a(CHEBI:"hydrogen peroxide") directlyDecreases bp(GOBP:"cell redox homeostasis")
pmid:18675468	a(CHEBI:"hydrogen peroxide") increases bp(GOBP:"membrane lipid catabolic process")
pmid:23653222	a(CHEBI:"hydrogen peroxide") isA a(CHEBI:"reactive oxygen species")
pmid:22235318	a(CHEBI:"hydrogen peroxide") increases a(CHEBI:"reactive oxygen species")
pmid:22235318	a(CHEBI:"hydrogen peroxide") increases bp(GOBP:"cell death")
pmid:11226677	a(CHEBI:"hydrogen peroxide") increases bp(MESHPP:"Oxidative Stress")
pmid:11226677	a(CHEBI:"hydrogen peroxide") increases bp(MESHPP:"Oxidative Stress")
pmid:17869087	a(CHEBI:"hydrogen peroxide") decreases p(HGNC:BCL2L1)
pmid:17869087	a(CHEBI:"hydrogen peroxide") increases p(HGNC:CASP3)
pmid:17869087	a(CHEBI:"hydrogen peroxide") increases p(HGNC:CASP8)
pmid:17869087	a(CHEBI:"hydrogen peroxide") increases p(HGNC:MAPK8, pmod(Ph))
pmid:20044591	a(CHEBI:"hydrogen peroxide") association r(HGNC:LAMB2)
pmid:20044591	a(CHEBI:"hydrogen peroxide") association r(HGNC:LAMC2)
pmid:17553629	a(CHEBI:acetylcholine) negativeCorrelation path(MESHD:Inflammation)
pmid:8584603	a(CHEBI:acetylcholine) increases a(CHEBI:cortisol)
pmid:8584603	a(CHEBI:acetylcholine) regulates a(CHEBI:"growth hormone")
pmid:8584603	a(CHEBI:acetylcholine) regulates a(CHEBI:"Luteinizing hormone")
pmid:8584603	a(CHEBI:acetylcholine) regulates a(CHEBI:vasopressin)
pmid:8584603	a(CHEBI:acetylcholine) negativeCorrelation bp(GOBP:"prolactin secretion")
pmid:16426583	a(CHEBI:acetylcholine) association p(HGNC:CHRNA2)
pmid:16426583	a(CHEBI:acetylcholine) association p(HGNC:CHRNA3)
pmid:16426583	a(CHEBI:acetylcholine) association p(HGNC:CHRNA4)
pmid:16426583	a(CHEBI:acetylcholine) association p(HGNC:CHRNA5)
pmid:16426583	a(CHEBI:acetylcholine) association p(HGNC:CHRNA6)
pmid:16426583	a(CHEBI:acetylcholine) association p(HGNC:CHRNA7)
pmid:16426583	a(CHEBI:acetylcholine) association p(HGNC:CHRNA9)
pmid:16426583	a(CHEBI:acetylcholine) association p(HGNC:CHRNA10)
pmid:16426583	a(CHEBI:acetylcholine) association p(HGNC:CHRNB2)
pmid:16426583	a(CHEBI:acetylcholine) association p(HGNC:CHRNB3)
pmid:16426583	a(CHEBI:acetylcholine) association p(HGNC:CHRNB4)
pmid:16426583	a(CHEBI:acetylcholine) increases a(CHEBI:serotonin)
pmid:23557940	a(CHEBI:acetylcholine) increases p(HGNC:GNRH1)
pmid:9325095	a(CHEBI:acetylcholine) association act(p(HGNC:ACHE))
pmid:1791534	a(CHEBI:arecoline) isA a(CHEBI:"muscarinic agonist")
pmid:1791534	a(CHEBI:arecoline) decreases path(MESHD:"Alzheimer Disease")
pmid:1775605	a(CHEBI:arecoline) increases bp(GOBP:memory)
pmid:8019853	a(CHEBI:arecoline) increases bp(GOBP:memory)
pmid:8019853	a(CHEBI:arecoline) increases bp(GOBP:"glucose metabolic process")
pmid:8019853	a(CHEBI:arecoline) increases bp(GOBP:"blood circulation")
pmid:8019853	a(CHEBI:arecoline) increases bp(GOBP:cognition)
pmid:8584603	a(CHEBI:arecoline) increases a(CHEBI:corticotropin)
pmid:20938992	a(CHEBI:choline) negativeCorrelation p(MGI:Chrnb1)
pmid:20938992	a(CHEBI:choline) association r(MGI:Gabrb3)
pmid:20938992	a(CHEBI:choline) association r(MGI:Mycn)
pmid:8584603	a(CHEBI:corticotropin) increases bp(GOBP:"neuron-neuron synaptic transmission")
pmid:8584603	a(CHEBI:corticotropin) increases bp(GOBP:cognition)
pmid:8584603	a(CHEBI:cortisol) increases bp(GOBP:"neuron-neuron synaptic transmission")
pmid:8584603	a(CHEBI:cortisol) increases bp(GOBP:cognition)
pmid:19383491	a(CHEBI:cortisol) association bp(MESHPP:"Insulin Resistance")
pmid:19383491	a(CHEBI:cortisol) positiveCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:18070217	a(CHEBI:donepezil) isA a(CHEBI:"EC 3.1.1.7 (acetylcholinesterase) inhibitor")
pmid:12007670	a(CHEBI:donepezil) isA a(CHEBI:"EC 3.1.1.7 (acetylcholinesterase) inhibitor")
pmid:18070217	a(CHEBI:donepezil) decreases p(HGNC:ACHE)
pmid:12007670	a(CHEBI:donepezil) directlyDecreases act(p(HGNC:ACHE))
pmid:18070217	a(CHEBI:donepezil) increases bp(GOBP:cognition)
pmid:17627484	a(CHEBI:donepezil) increases bp(GOBP:memory)
pmid:12007670	a(CHEBI:donepezil) regulates bp(GOBP:"amyloid precursor protein metabolic process")
pmid:23711227	a(CHEBI:donepezil) decreases p(CHEBI:"amyloid-beta polypeptide 42")
pmid:23711227	a(CHEBI:donepezil) decreases act(p(HGNC:GSK3B))
pmid:23711227	a(CHEBI:donepezil) increases act(p(HGNC:CHRNA2))
pmid:23711227	a(CHEBI:donepezil) increases act(p(HGNC:CHRNA3))
pmid:23711227	a(CHEBI:donepezil) increases act(p(HGNC:CHRNA4))
pmid:23711227	a(CHEBI:donepezil) increases act(p(HGNC:CHRNA5))
pmid:23711227	a(CHEBI:donepezil) increases act(p(HGNC:CHRNA6))
pmid:23711227	a(CHEBI:donepezil) increases act(p(HGNC:CHRNA7))
pmid:23711227	a(CHEBI:donepezil) increases act(p(HGNC:CHRNA9))
pmid:23711227	a(CHEBI:donepezil) increases act(p(HGNC:CHRNA10))
pmid:23711227	a(CHEBI:donepezil) increases act(p(HGNC:CHRNB2))
pmid:23711227	a(CHEBI:donepezil) increases act(p(HGNC:CHRNB3))
pmid:23711227	a(CHEBI:donepezil) increases act(p(HGNC:CHRNB4))
pmid:21893081	a(CHEBI:donepezil) decreases bp(GOBP:"neuron death")
pmid:21893081	a(CHEBI:donepezil) causesNoChange a(CHEBI:"reactive oxygen species")
pmid:11711029	a(CHEBI:estradiol) decreases act(a(MESHC:Acetylcholine))
pmid:21826169	a(CHEBI:estradiol) association r(HGNC:AIFM1)
pmid:16000229	a(CHEBI:estradiol) regulates r(HGNC:GABRA4)
pmid:16000229	a(CHEBI:estradiol) increases r(HGNC:GABRA3)
pmid:16000229	a(CHEBI:estradiol) increases r(HGNC:GABRB3)
pmid:23373633	a(CHEBI:estradiol) decreases r(HGNC:LCK)
pmid:23373633	a(CHEBI:estradiol) association r(HGNC:NOL3)
pmid:17404688	a(CHEBI:estradiol) association r(HGNC:MYCN)
pmid:15598477	a(CHEBI:galanthamine) increases bp(GOBP:cognition)
pmid:15598477	a(CHEBI:galanthamine) increases bp(GOBP:behavior)
pmid:15530663	a(CHEBI:galanthamine) isA a(CHEBI:"EC 3.1.1.7 (acetylcholinesterase) inhibitor")
pmid:15530663	a(CHEBI:galanthamine) decreases act(p(HGNC:ACHE))
pmid:15530663	a(CHEBI:galanthamine) isA a(CHEBI:"nicotinic acetylcholine receptor agonist")
pmid:11230880	a(CHEBI:galanthamine) increases a(CHEBI:acetylcholine)
pmid:11230880	a(CHEBI:galanthamine) increases bp(GOBP:"synaptic transmission, cholinergic")
pmid:11230880	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA2))
pmid:19272425	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA2))
pmid:11230880	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA3))
pmid:19272425	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA3))
pmid:11230880	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA4))
pmid:19272425	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA4))
pmid:11230880	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA5))
pmid:19272425	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA5))
pmid:11230880	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA6))
pmid:19272425	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA6))
pmid:11230880	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA7))
pmid:19272425	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA7))
pmid:11230880	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA9))
pmid:19272425	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA9))
pmid:11230880	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA10))
pmid:19272425	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNA10))
pmid:11230880	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNB2))
pmid:19272425	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNB2))
pmid:11230880	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNB3))
pmid:19272425	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNB3))
pmid:11230880	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNB4))
pmid:19272425	a(CHEBI:galanthamine) increases act(p(HGNC:CHRNB4))
pmid:17213958	a(CHEBI:glutathione) directlyIncreases bp(GOBP:"cell redox homeostasis")
pmid:17213958	a(CHEBI:glutathione) directlyDecreases act(p(HGNC:ACHE), ma(pep))
pmid:16179266	a(CHEBI:glutathione) increases p(FPLX:SOD)
pmid:16179266	a(CHEBI:glutathione) increases p(ECCODE:"1.15.1.1")
pmid:20847424	a(CHEBI:glutathione) decreases bp(MESHPP:"Oxidative Stress")
pmid:20847424	a(CHEBI:glutathione) decreases a(CHEBI:"reactive oxygen species")
pmid:20170836	a(CHEBI:memantine) increases bp(GOBP:cognition)
pmid:21893081	a(CHEBI:memantine) decreases bp(GOBP:"neuron death")
pmid:20042680	a(CHEBI:memantine) decreases a(HBP:"amyloid-beta oligomers")
pmid:20042680	a(CHEBI:memantine) decreases p(HGNC:APP, frag("672_713"))
pmid:20042680	a(CHEBI:memantine) positiveCorrelation bp(MESHPP:"Long-Term Potentiation")
pmid:24846616	a(CHEBI:memantine) decreases p(MGI:App, frag("672_713"))
pmid:24846616	a(CHEBI:memantine) decreases p(MGI:App)
pmid:21893081	a(CHEBI:memantine) decreases a(CHEBI:"reactive oxygen species")
pmid:20042680	a(CHEBI:memantine) decreases p(MGI:Mapt)
pmid:20042680	a(CHEBI:memantine) decreases p(MGI:Mapt, pmod(Ph))
pmid:20938992	a(CHEBI:methionine) negativeCorrelation p(MGI:Chrnb1)
pmid:9201800	a(CHEBI:nefiracetam) increases bp(GOBP:cognition)
pmid:11039729	a(CHEBI:nefiracetam) increases bp(GOBP:cognition)
pmid:7838908	a(CHEBI:nefiracetam) increases bp(GOBP:cognition)
pmid:17095583	a(CHEBI:nefiracetam) increases act(p(HGNC:GRIN2B))
pmid:21821968	a(CHEBI:nefiracetam) increases act(p(HGNC:GRIN2B))
pmid:17095583	a(CHEBI:nefiracetam) increases act(p(HGNC:CHRNA2))
pmid:17095583	a(CHEBI:nefiracetam) increases act(p(HGNC:CHRNA3))
pmid:17095583	a(CHEBI:nefiracetam) increases act(p(HGNC:CHRNA4))
pmid:17095583	a(CHEBI:nefiracetam) increases act(p(HGNC:CHRNA5))
pmid:17095583	a(CHEBI:nefiracetam) increases act(p(HGNC:CHRNA6))
pmid:17095583	a(CHEBI:nefiracetam) increases act(p(HGNC:CHRNA7))
pmid:17095583	a(CHEBI:nefiracetam) increases act(p(HGNC:CHRNA9))
pmid:17095583	a(CHEBI:nefiracetam) increases act(p(HGNC:CHRNA10))
pmid:17095583	a(CHEBI:nefiracetam) increases act(p(HGNC:CHRNB2))
pmid:17095583	a(CHEBI:nefiracetam) increases act(p(HGNC:CHRNB3))
pmid:19272425	a(CHEBI:nefiracetam) isA a(CHEBI:"EC 3.1.1.7 (acetylcholinesterase) inhibitor")
pmid:21821968	a(CHEBI:nefiracetam) increases act(complex(SCOMP:"CAMK2 Complex"))
pmid:21821968	a(CHEBI:nefiracetam) increases act(complex(SCOMP:"CAMK2 Complex"))
pmid:11039729	a(CHEBI:nefiracetam) increases complex(a(CHEBI:nefiracetam), p(HGNC:PRKCA))
pmid:17095583	a(CHEBI:nefiracetam) increases act(p(HGNC:PRKCA))
pmid:17095583	a(CHEBI:nefiracetam) causesNoChange bp(GOBP:"protein kinase A signaling")
pmid:21821968	a(CHEBI:nefiracetam) increases bp(GOBP:"long-term synaptic potentiation")
pmid:1791534	a(CHEBI:physostigmine) isA a(CHEBI:"EC 3.1.1.8 (cholinesterase) inhibitor")
pmid:1791534	a(CHEBI:physostigmine) decreases path(MESHD:"Alzheimer Disease")
pmid:18089832	a(CHEBI:resveratrol) decreases p(HGNC:CHRNB1)
pmid:11577002	a(CHEBI:resveratrol) decreases p(HGNC:BIRC2)
pmid:16617056	a(CHEBI:resveratrol) increases p(HGNC:AIFM1)
pmid:20715097	a(CHEBI:resveratrol) decreases p(MGI:Il2ra)
pmid:21852083	a(CHEBI:resveratrol) decreases r(HGNC:MYCN)
pmid:12860489	a(CHEBI:rivastigmine) isA a(CHEBI:"EC 3.1.1.7 (acetylcholinesterase) inhibitor")
pmid:12860489	a(CHEBI:rivastigmine) increases bp(GOBP:cognition)
pmid:12860489	a(CHEBI:rivastigmine) increases bp(GOBP:behavior)
pmid:22323348	a(CHEBI:rivastigmine) decreases p(HGNC:ACHE)
pmid:23291013	a(CHEBI:rivastigmine) decreases p(HGNC:ACHE)
pmid:22323348	a(CHEBI:rivastigmine) decreases p(HGNC:BCHE)
pmid:20054753	a(CHEBI:rivastigmine) increases p(HGNC:APP, frag("672_713"))
pmid:17691220	a(CHEBI:rivastigmine) increases p(HGNC:APP, frag("672_713"))
pmid:17691220	a(CHEBI:rivastigmine) association p(HGNC:APP)
pmid:21799757	a(CHEBI:rivastigmine) increases tloc(p(HGNC:APP), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:17691220	a(CHEBI:rivastigmine) causesNoChange p(HGNC:APP, frag("672_711"))
pmid:18692909	a(CHEBI:rivastigmine) decreases bp(GOBP:"neuron death")
pmid:19445928	a(CHEBI:rivastigmine) increases p(RGD:Sod1)
pmid:19445928	a(CHEBI:rivastigmine) increases p(RGD:Sod2)
pmid:18692909	a(CHEBI:rivastigmine) decreases path(MESHD:Inflammation)
pmid:18692909	a(CHEBI:rivastigmine) decreases bp(GOBP:"negative regulation of myelination")
pmid:22524398	a(CHEBI:rivastigmine) increases p(HGNC:IGF1)
pmid:23469045	a(CHEBI:rivastigmine) decreases act(p(HGNC:MPO))
pmid:21799757	a(CHEBI:rivastigmine) increases bp(GO:"GO:0050435")
pmid:21799757	a(CHEBI:rivastigmine) increases a(HBP:"sAPP-alpha")
pmid:21799757	a(CHEBI:rivastigmine) increases a(HBP:"sAPP-alpha")
pmid:21799757	a(CHEBI:rivastigmine) decreases a(CHEBI:"amyloid-beta")
pmid:21799757	a(CHEBI:rivastigmine) increases bp(MESH:D000066829)
pmid:21799757	a(CHEBI:rivastigmine) increases act(p(HGNC:ADAM10))
pmid:15258105	a(CHEBI:tacrine) decreases path(MESHD:"Alzheimer Disease")
pmid:20533758	a(CHEBI:tacrine) increases bp(GOBP:"blood circulation")
pmid:20533758	a(CHEBI:tacrine) decreases path(MESHD:Inflammation)
pmid:8584603	a(CHEBI:vasopressin) increases bp(GOBP:"neuron-neuron synaptic transmission")
pmid:8584603	a(CHEBI:vasopressin) increases bp(GOBP:cognition)
pmid:23759148	act(a(MESH:D001253)) positiveCorrelation act(p(HGNC:BCHE))
pmid:19394434	act(a(MESH:D001253)) increases a(CHEBI:"amyloid-beta")
pmid:22047170	a(MESH:D001253) increases a(CHEBI:"amyloid-beta")
pmid:24694234	a(MESH:D001253) increases a(CHEBI:"amyloid-beta")
pmid:22047170	act(a(MESH:D001253)) increases a(CHEBI:"amyloid-beta")
pmid:11553277	a(MESH:D001253) association p(HGNC:APP)
pmid:24694234	a(MESH:D001253) increases p(HGNC:APP)
pmid:11553277	a(MESH:D001253) increases bp(PTS:"amyloidogenic pathway")
pmid:24694234	a(MESH:D001253) association path(MESHD:"Cognitive Dysfunction")
pmid:19885299	a(MESH:D001253) association path(MESHD:Inflammation)
pmid:21143158	a(MESH:D001253) increases bp(GOBP:"inflammatory response")
pmid:20413894	a(MESH:D001253) association bp(GOBP:"inflammatory response")
pmid:15474976	a(MESH:D001253) positiveCorrelation bp(HBP:neuroinflammation)
pmid:19885299	act(a(MESH:D001253)) negativeCorrelation p(HGNC:INS)
pmid:19885299	act(a(MESH:D001253)) negativeCorrelation p(HGNC:IGF1)
pmid:19885299	act(a(MESH:D001253)) negativeCorrelation p(HGNC:IGF2)
pmid:19885299	act(a(MESH:D001253)) increases bp(MESHPP:"Insulin Resistance")
pmid:22383525	a(MESH:D001253) increases deg(p(HGNC:APP, frag("672_713")))
pmid:24691121	a(MESH:D001253) increases p(HGNC:ICAM1)
pmid:12788508	a(MESH:D017628) increases bp(GOBP:"inflammatory response")
pmid:15232608	a(MESH:D017628) association bp(GOBP:"inflammatory response")
pmid:15232608	a(MESH:D017628) association bp(GOBP:"microglial cell activation involved in immune response")
pmid:15232608	a(MESH:D017628) association a(CHEBI:"amyloid-beta")
pmid:20205643	a(MESH:D017628) association a(CHEBI:"amyloid-beta")
pmid:11755016	a(MESH:D017628) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:19885299	a(MESH:D017628) association path(MESHD:Inflammation)
pmid:15474976	a(MESH:D017628) positiveCorrelation bp(HBP:neuroinflammation)
pmid:11755016	a(MESH:D017628) increases bp(GOBP:"neuron death")
pmid:23407992	a(MESH:D017628) increases bp(GOBP:"cytokine production")
pmid:23407992	a(MESH:D017628) increases bp(GOBP:"cytokine secretion")
pmid:19519303	act(a(MESH:D017628)) increases deg(p(HGNC:APP, frag("672_713")))
pmid:22383525	a(MESH:D017628) increases deg(p(HGNC:APP, frag("672_713")))
pmid:18835047	a(MESH:D017628) decreases p(HGNC:APP, frag("672_713"))
pmid:19885299	act(a(MESH:D017628)) negativeCorrelation p(HGNC:INS)
pmid:19885299	act(a(MESH:D017628)) negativeCorrelation p(HGNC:IGF1)
pmid:20701773	act(a(MESH:D017628)) increases tloc(p(HGNC:IGF1), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:19885299	act(a(MESH:D017628)) negativeCorrelation p(HGNC:IGF2)
pmid:19885299	act(a(MESH:D017628)) increases bp(MESHPP:"Insulin Resistance")
pmid:16399206	a(MESH:D017628) increases tloc(p(HGNC:IDE), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:20701773	act(a(MESH:D017628)) increases tloc(p(HGNC:TNF), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:11711029	a(MESHC:Acetylcholine) regulates act(complex(p(HGNC:CHRNA3), p(HGNC:CHRNB4)))
pmid:9336329	a(MESHC:pozanicline) decreases act(complex(p(HGNC:CHRNA1), p(HGNC:CHRNB1), p(HGNC:CHRND), p(HGNC:CHRNG)))
pmid:3484831	a(NIFT:"Cerebral atrophy") positiveCorrelation p(HGNC:ACHE)
pmid:25570489	a(NIFT:"Cerebral atrophy") association p(HGNC:APP)
pmid:19885299	bp(GOBP:"acetylcholine secretion") positiveCorrelation p(HGNC:INS)
pmid:19885299	bp(GOBP:"acetylcholine secretion") positiveCorrelation p(HGNC:IGF1)
pmid:19885299	bp(GOBP:"acetylcholine secretion") positiveCorrelation bp(GOBP:cognition)
pmid:9325095	bp(GOBP:"amyloid fibril formation") increases complex(p(HGNC:ACHE), p(HGNC:APP, frag("672_713")))
pmid:18297066	bp(GOBP:"amyloid fibril formation") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE))
pmid:7639323	bp(GOBP:"amyloid fibril formation") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE))
pmid:21352095	bp(GOBP:"amyloid precursor protein metabolic process") association a(CHEBI:glucose)
pmid:19419557	bp(GOBP:"calcium ion import") increases a(CHEBI:"amyloid-beta")
pmid:19383491	bp(GOBP:"calcium ion import") increases act(p(HGNC:CAMK2A))
pmid:19383491	bp(GOBP:"calcium ion import") association bp(GOBP:"chemical synaptic transmission")
pmid:22496686	bp(GOBP:"calcium ion import") association act(complex(GOCC:"NMDA selective glutamate receptor complex"))
pmid:17316694	bp(GOBP:"glucose metabolic process") negativeCorrelation bp(GOBP:"regulation of insulin receptor signaling pathway")
pmid:15232608	bp(GOBP:"inflammatory response") association a(MESH:D017628)
pmid:15232608	bp(GOBP:"inflammatory response") association path(MESHD:"Neurogenic Inflammation")
pmid:21903077	bp(GOBP:"inflammatory response") association path(MESHD:"Alzheimer Disease")
pmid:18715507	bp(GOBP:"inflammatory response") positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22209051	bp(GOBP:"inflammatory response") increases path(MESHD:"Alzheimer Disease")
pmid:22198949	bp(GOBP:"inflammatory response") increases path(MESHD:"Alzheimer Disease")
pmid:20413894	bp(GOBP:"inflammatory response") association path(MESHD:"Alzheimer Disease")
pmid:22441986	bp(GOBP:"inflammatory response") positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22279475	bp(GOBP:"inflammatory response") association g(HGNC:TNF, var("c.308G>A"))
pmid:20555131	bp(GOBP:"inflammatory response") association p(HGNC:GFAP)
pmid:20555131	bp(GOBP:"inflammatory response") association p(HGNC:TNF)
pmid:20555131	bp(GOBP:"inflammatory response") association p(HGNC:IL6)
pmid:22493750	bp(GOBP:"inflammatory response") association p(HGNC:IL6)
pmid:18715507	bp(GOBP:"inflammatory response") positiveCorrelation bp(GOBP:"microglial cell activation involved in immune response")
pmid:22493750	bp(GOBP:"inflammatory response") association p(HGNC:PPARA)
pmid:22493750	bp(GOBP:"inflammatory response") association p(HGNC:IL1A)
pmid:22493750	bp(GOBP:"inflammatory response") association p(HGNC:IL1B)
pmid:21515354	bp(GOBP:"inflammatory response") increases p(HGNC:IL1B)
pmid:22493750	bp(GOBP:"inflammatory response") association p(HGNC:IL10)
pmid:19801956	bp(GOBP:"inflammatory response") association m(HGNC:MIR146A)
pmid:22209051	bp(GOBP:"inflammatory response") positiveCorrelation m(HGNC:MIR146A)
pmid:20489155	bp(GOBP:"inflammatory response") association p(HGNC:GRN)
pmid:21036908	bp(GOBP:"inflammatory response") association m(HGNC:MIR155)
pmid:18615183	bp(GOBP:"inflammatory response") association p(HGNC:TLR2)
pmid:24262633	bp(GOBP:"inflammatory response") association act(p(HGNC:NFE2L2))
pmid:17572512	bp(GOBP:"inflammatory response") association complex(p(HGNC:CD36), p(HGNC:CD47), p(HGNC:THBS1))
pmid:18759972	bp(GOBP:"inflammatory response") increases a(CHEBI:"amyloid-beta")
pmid:18759972	bp(GOBP:"inflammatory response") decreases bp(GOBP:cognition)
pmid:18637012	bp(GOBP:"inflammatory response") negativeCorrelation bp(GOBP:cognition)
pmid:18637012	bp(GOBP:"inflammatory response") negativeCorrelation path(HP:"Brain atrophy")
pmid:18615183	bp(GOBP:"inflammatory response") association p(HGNC:CD14)
pmid:18615183	bp(GOBP:"inflammatory response") association p(HGNC:MYD88)
pmid:12675915	bp(GOBP:"inflammatory response") increases r(MGI:Il1b)
pmid:12675915	bp(GOBP:"inflammatory response") increases r(MGI:Nos2)
pmid:10417811	bp(GOBP:"inflammatory response") increases bp(GOBP:"neuron death")
pmid:20413894	bp(GOBP:"inflammatory response") association a(MESH:D001253)
pmid:23533697	bp(GOBP:"inflammatory response") association p(HGNC:TREM2)
pmid:23407992	bp(GOBP:"inflammatory response") association bp(GOBP:"cytokine production")
pmid:23407992	bp(GOBP:"inflammatory response") association bp(GOBP:"cytokine secretion")
pmid:21903077	bp(GOBP:"inflammatory response") increases p(HGNC:NOS2)
pmid:12769595	bp(GOBP:"learning or memory") association p(HGNC:GAL)
pmid:20385830	bp(GOBP:"learning or memory") association bp(MESHPP:"Long-Term Potentiation")
pmid:19885299	bp(GOBP:"learning or memory") positiveCorrelation p(HGNC:INS)
pmid:19519303	bp(GOBP:"learning or memory") association act(p(HGNC:INS))
pmid:19519303	bp(GOBP:"learning or memory") association act(p(HGNC:IGF1))
pmid: 22646481	bp(GOBP:"learning or memory") association act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits"))
pmid: 22646481	bp(GOBP:"learning or memory") association act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits"))
pmid:19885299	bp(GOBP:"long term synaptic depression") negativeCorrelation bp(GOBP:cognition)
pmid:19885299	bp(GOBP:"long term synaptic depression") negativeCorrelation p(HGNC:INS)
pmid:19885299	bp(GOBP:"long term synaptic depression") negativeCorrelation p(HGNC:IGF1)
pmid: 22646481	bp(GOBP:"long term synaptic depression") association act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits"))
pmid:12769595	bp(GOBP:"negative regulation of synaptic transmission, cholinergic") association p(HGNC:GAL)
pmid:15232608	bp(GOBP:"neuron apoptotic process") isA bp(GOBP:"apoptotic process")
pmid:22496686	bp(GOBP:"neuron apoptotic process") association bp(GOBP:"cell cycle")
pmid:22496686	bp(GOBP:"neuron apoptotic process") association act(p(SFAM:"MAPK Erk1/2 Family"))
pmid:20847424	bp(GOBP:"neuron apoptotic process") positiveCorrelation act(p(HGNC:GSK3B))
pmid:16687508	bp(GOBP:"neuron death") association path(MESHD:"Alzheimer Disease")
pmid:21666500	bp(GOBP:"neuron death") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:16914869	bp(GOBP:"neuron death") association p(HGNC:GSK3B)
pmid:22496686	bp(GOBP:"neuron death") association bp(GOBP:"Notch signaling pathway")
pmid:19625741	bp(GOBP:"neuron death") positiveCorrelation p(HGNC:GRN)
pmid:23557940	bp(GOBP:"neuron death") negativeCorrelation act(p(HGNC:IGF1))
pmid:23557940	bp(GOBP:"neuron death") positiveCorrelation bp(MESHPP:"Insulin Resistance")
pmid: 22646481	bp(GOBP:"neuron death") association p(HGNC:APP, frag("672_713"))
pmid:14970312	bp(GOBP:"neuron death") increases a(NIFT:"Hippocampal atrophy")
pmid:14970312	bp(GOBP:"neuron death") increases a(NIFT:"Hippocampal atrophy")
pmid:22426017	bp(GOBP:"neuron death") increases a(NIFT:"Cortical Thinning")
pmid:26235064	bp(GOBP:"neuron death") association p(HGNC:MAPT)
pmid:8584603	bp(GOBP:"neuron-neuron synaptic transmission") increases bp(GOBP:cognition)
pmid:8584603	bp(GOBP:"prolactin secretion") negativeCorrelation a(CHEBI:acetylcholine)
pmid:12675140	bp(GOBP:"regulation of synaptic transmission, cholinergic") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:12675140	bp(GOBP:"regulation of synaptic transmission, cholinergic") increases a(CHEBI:"amyloid-beta")
pmid:12675140	bp(GOBP:"regulation of synaptic transmission, cholinergic") increases bp(GOBP:cognition)
pmid:21821968	bp(GOBP:"regulation of synaptic transmission, cholinergic") increases bp(GOBP:cognition)
pmid:21821968	bp(GOBP:"regulation of synaptic transmission, cholinergic") increases bp(GOBP:learning)
pmid:21821968	bp(GOBP:"regulation of synaptic transmission, cholinergic") increases bp(GOBP:memory)
pmid:19885299	bp(GOBP:cognition) negativeCorrelation bp(GOBP:"long term synaptic depression")
pmid:19885299	bp(GOBP:cognition) positiveCorrelation bp(MESHPP:"Neuronal Plasticity")
pmid:19885299	bp(GOBP:cognition) positiveCorrelation bp(GOBP:"acetylcholine secretion")
pmid:20170836	bp(GOBP:cognition) positiveCorrelation a(CHEBI:"(R)-flurbiprofen")
pmid:18637012	bp(GOBP:cognition) negativeCorrelation bp(GOBP:"inflammatory response")
pmid:19885299	bp(GOBP:cognition) negativeCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:22236693	bp(GOBP:cognition) negativeCorrelation g(HGNC:NGFR)
pmid:24884485	bp(GOBP:cognition) negativeCorrelation p(HGNC:IL6)
pmid:24884485	bp(GOBP:cognition) negativeCorrelation p(HGNC:MAPT)
pmid:26235064	bp(GOBP:cognition) association p(HGNC:MAPT)
pmid:24884485	bp(GOBP:cognition) negativeCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:15084661	bp(GOBP:memory) negativeCorrelation a(CHEBI:"amyloid-beta")
pmid:19885299	bp(HBP:"neurite retraction") decreases bp(GOBP:cognition)
pmid:19885299	bp(HBP:"neurite retraction") negativeCorrelation p(HGNC:INS)
pmid:19885299	bp(HBP:"neurite retraction") negativeCorrelation p(HGNC:IGF1)
pmid:15474976	bp(HBP:neuroinflammation) positiveCorrelation p(HGNC:CHRNA5)
pmid:15474976	bp(HBP:neuroinflammation) positiveCorrelation p(HGNC:CHRNA3)
pmid:15474976	bp(HBP:neuroinflammation) positiveCorrelation p(HGNC:CHRNA7)
pmid:15474976	bp(HBP:neuroinflammation) positiveCorrelation p(HGNC:CHRNA4)
pmid:15474976	bp(HBP:neuroinflammation) positiveCorrelation p(HGNC:CHRNB2)
pmid:15474976	bp(HBP:neuroinflammation) positiveCorrelation p(HGNC:PPARG)
pmid:15474976	bp(HBP:neuroinflammation) positiveCorrelation a(MESH:D017628)
pmid:15474976	bp(HBP:neuroinflammation) positiveCorrelation a(MESH:D001253)
pmid:15474976	bp(HBP:neuroinflammation) positiveCorrelation p(HGNC:PTX3)
pmid:24694234	bp(HBP:neuroinflammation) association path(MESHD:"Alzheimer Disease")
pmid:24863743	bp(HBP:neuroinflammation) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:26836182	bp(HBP:neuroinflammation) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22566778	bp(HBP:neuroinflammation) positiveCorrelation p(HGNC:IL1A)
pmid:22566778	bp(HBP:neuroinflammation) positiveCorrelation p(HGNC:IL6)
pmid:22566778	bp(HBP:neuroinflammation) positiveCorrelation p(HGNC:TNF)
pmid:24586483	bp(HBP:neuroinflammation) association m(HGNC:MIR146A)
pmid:24694234	bp(HBP:neuroinflammation) increases bp(GOBP:"innate immune response")
pmid:24694234	bp(HBP:neuroinflammation) increases act(p(GFAM:"Toll like receptors"))
pmid:24863743	bp(HBP:neuroinflammation) positiveCorrelation path(MESHD:Stroke)
pmid:24863743	bp(HBP:neuroinflammation) positiveCorrelation path(MESHD:"Multiple Sclerosis")
pmid:24863743	bp(HBP:neuroinflammation) positiveCorrelation path(MESHD:"Brain Injuries, Traumatic")
pmid:24863743	bp(HBP:neuroinflammation) positiveCorrelation path(MESHD:"Parkinson Disease")
pmid:22890100	bp(HBP:neuroinflammation) positiveCorrelation p(HGNC:CHI3L1)
pmid:26836182	bp(HBP:neuroinflammation) positiveCorrelation p(HGNC:CHI3L1)
pmid:26836182	bp(HBP:neuroinflammation) positiveCorrelation bp(GOBP:"microglial cell activation")
pmid:26836182	bp(HBP:neuroinflammation) positiveCorrelation p(HGNC:CCL2)
pmid:19885299	bp(MESHPP:"Insulin Resistance") decreases bp(GOBP:"acetylcholine secretion")
pmid:17096857	bp(MESHPP:"Insulin Resistance") association p(HGNC:ACHE)
pmid:22829447	bp(MESHPP:"Insulin Resistance") positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22536436	bp(MESHPP:"Insulin Resistance") association path(MESHD:"Alzheimer Disease")
pmid:19519303	bp(MESHPP:"Insulin Resistance") association path(MESHD:"Alzheimer Disease")
pmid:23627755	bp(MESHPP:"Insulin Resistance") association path(MESHD:"Alzheimer Disease")
pmid:22829447	bp(MESHPP:"Insulin Resistance") increases a(CHEBI:"amyloid-beta")
pmid:22536436	bp(MESHPP:"Insulin Resistance") positiveCorrelation a(CHEBI:glucocorticoid)
pmid:22536436	bp(MESHPP:"Insulin Resistance") association p(HGNC:MAPT, pmod(Ph))
pmid:23627755	bp(MESHPP:"Insulin Resistance") association p(HGNC:MAPT, pmod(Ph))
pmid:22536436	bp(MESHPP:"Insulin Resistance") association act(p(HGNC:CAPN1))
pmid:19885299	bp(MESHPP:"Insulin Resistance") positiveCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:23627755	bp(MESHPP:"Insulin Resistance") association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:19885299	bp(MESHPP:"Insulin Resistance") negativeCorrelation p(HGNC:INSR)
pmid:19885299	bp(MESHPP:"Insulin Resistance") negativeCorrelation act(p(HGNC:INSR))
pmid:19885299	bp(MESHPP:"Insulin Resistance") negativeCorrelation p(HGNC:IRS1)
pmid:19885299	bp(MESHPP:"Insulin Resistance") negativeCorrelation bp(GOBP:"insulin receptor signaling pathway via phosphatidylinositol 3-kinase")
pmid:19885299	bp(MESHPP:"Insulin Resistance") negativeCorrelation a(GOCC:cytoskeleton)
pmid:19885299	bp(MESHPP:"Insulin Resistance") increases bp(HBP:"neurite retraction")
pmid:19885299	bp(MESHPP:"Insulin Resistance") increases bp(GOBP:"long term synaptic depression")
pmid:19885299	bp(MESHPP:"Insulin Resistance") decreases bp(MESHPP:"Neuronal Plasticity")
pmid:19885299	bp(MESHPP:"Insulin Resistance") association g(HGNC:APOE)
pmid:19519303	bp(MESHPP:"Insulin Resistance") decreases bp(GOBP:cognition)
pmid:19519303	bp(MESHPP:"Insulin Resistance") decreases bp(GOBP:memory)
pmid:19519303	bp(MESHPP:"Insulin Resistance") positiveCorrelation bp(MESHPP:Obesity)
pmid:19519303	bp(MESHPP:"Insulin Resistance") association p(HGNC:IRS1, var("p.Gly972Arg"))
pmid:19383491	bp(MESHPP:"Insulin Resistance") association a(CHEBI:cortisol)
pmid:23557940	bp(MESHPP:"Insulin Resistance") positiveCorrelation bp(GOBP:"neuron death")
pmid:23557940	bp(MESHPP:"Insulin Resistance") positiveCorrelation p(HGNC:APP, frag("672_713"))
pmid:23557940	bp(MESHPP:"Insulin Resistance") positiveCorrelation complex(GOCC:"neurofibrillary tangle")
pmid:19885299	bp(MESHPP:"Neuronal Plasticity") positiveCorrelation bp(GOBP:cognition)
pmid:19885299	bp(MESHPP:"Neuronal Plasticity") positiveCorrelation p(HGNC:INS)
pmid:19885299	bp(MESHPP:"Neuronal Plasticity") positiveCorrelation p(HGNC:IGF1)
pmid:19519303	bp(MESHPP:"Neuronal Plasticity") association bp(GOBP:"ERK1 and ERK2 cascade")
pmid:11523796	bp(PTS:"APP processing pathway") association complex(p(HGNC:APOE), p(HGNC:APP))
pmid:21821968	complex(SCOMP:"CAMK2 Complex") increases p(HGNC:GRIA1, pmod(Ph, Ser, 831))
pmid:15709485	complex(a(CHEBI:"amyloid-beta"), p(HGNC:ACHE)) increases bp(GOBP:"neuron death")
pmid:17681794	complex(a(CHEBI:"amyloid-beta"), p(HGNC:ACHE)) increases bp(GOBP:"neuron death")
pmid:22257528	act(p(HGNC:ACHE)) increases path(MESHD:"Alzheimer Disease")
pmid:22445674	p(HGNC:ACHE) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:17096857	p(HGNC:ACHE) association path(MESHD:"Alzheimer Disease")
pmid:17213958	act(p(HGNC:ACHE), ma(pep)) regulates bp(GOBP:"neuron apoptotic process")
pmid:17213958	act(p(HGNC:ACHE), ma(pep)) negativeCorrelation a(CHEBI:"hydrogen peroxide")
pmid:17096857	p(HGNC:ACHE) association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:17096857	p(HGNC:ACHE) association bp(MESHPP:"Insulin Resistance")
pmid:17096857	p(HGNC:ACHE) regulates bp(GOBP:"lipid metabolic process")
pmid:17553629	p(HGNC:ACHE) decreases a(CHEBI:acetylcholine)
pmid:9325095	act(p(HGNC:ACHE)) association a(CHEBI:acetylcholine)
pmid:15544503	p(HGNC:ACHE) association p(HGNC:APP, frag("672_713"))
pmid:18205831	p(HGNC:ACHE) increases p(HGNC:APP, frag("672_713"))
pmid:22431227	act(p(HGNC:ACHE)) association p(HGNC:APP, frag("672_713"))
pmid:22778810	p(HGNC:ACHE) increases a(CHEBI:"amyloid-beta")
pmid:17681794	p(HGNC:ACHE) increases a(CHEBI:"amyloid-beta")
pmid:9325095	p(HGNC:ACHE) increases a(CHEBI:"amyloid-beta")
pmid:18205831	p(HGNC:ACHE) increases p(HGNC:PRNP)
pmid:9325095	p(HGNC:ACHE) increases complex(p(HGNC:ACHE), p(HGNC:APP, frag("672_713")))
pmid:3484831	p(HGNC:ACHE) positiveCorrelation a(NIFT:"Cerebral atrophy")
pmid:20847424	complex(a(CHEBI:"amyloid-beta"), p(HGNC:GRIN1), p(SFAM:"Cholinesterase Family")) increases bp(GOBP:"positive regulation of calcium ion import")
pmid:19419557	act(p(HGNC:GRIN1)) increases a(CHEBI:"nitric oxide")
pmid:19419557	act(p(HGNC:GRIN1)) increases bp(GOBP:"negative regulation of calcium-mediated signaling")
pmid:11039729	complex(a(CHEBI:nefiracetam), p(HGNC:PRKCA)) increases act(p(HGNC:CHRNA2))
pmid:11039729	complex(a(CHEBI:nefiracetam), p(HGNC:PRKCA)) increases act(p(HGNC:CHRNA3))
pmid:11039729	complex(a(CHEBI:nefiracetam), p(HGNC:PRKCA)) increases act(p(HGNC:CHRNA4))
pmid:11039729	complex(a(CHEBI:nefiracetam), p(HGNC:PRKCA)) increases act(p(HGNC:CHRNA5))
pmid:11039729	complex(a(CHEBI:nefiracetam), p(HGNC:PRKCA)) increases act(p(HGNC:CHRNA6))
pmid:11039729	complex(a(CHEBI:nefiracetam), p(HGNC:PRKCA)) increases act(p(HGNC:CHRNA7))
pmid:11039729	complex(a(CHEBI:nefiracetam), p(HGNC:PRKCA)) increases act(p(HGNC:CHRNA9))
pmid:11039729	complex(a(CHEBI:nefiracetam), p(HGNC:PRKCA)) increases act(p(HGNC:CHRNA10))
pmid:11039729	complex(a(CHEBI:nefiracetam), p(HGNC:PRKCA)) increases act(p(HGNC:CHRNB2))
pmid:11039729	complex(a(CHEBI:nefiracetam), p(HGNC:PRKCA)) increases act(p(HGNC:CHRNB3))
pmid:11039729	complex(a(CHEBI:nefiracetam), p(HGNC:PRKCA)) increases act(p(HGNC:CHRNB4))
pmid:16303979	p(HGNC:PRKCA) increases bp(GOBP:"apoptotic process")
pmid:21192821	act(p(HGNC:PRKCA), ma(kin)) increases p(HGNC:SORL1, pmod(Ph))
pmid:9775403	p(HGNC:PRKCA) increases p(HGNC:APP)
pmid:8584603	act(complex(a(MESH:D007031), a(MESH:D010902))) increases a(CHEBI:corticotropin)
pmid:8584603	act(complex(a(MESH:D007031), a(MESH:D010902))) increases a(CHEBI:cortisol)
pmid:8584603	act(complex(a(MESH:D007031), a(MESH:D010902))) increases a(CHEBI:vasopressin)
pmid:8584603	act(complex(a(MESH:D007031), a(MESH:D010902))) increases a(CHEBI:"(R)-adrenaline")
pmid:8584603	act(complex(a(MESH:D007031), a(MESH:D010902))) increases bp(GOBP:cognition)
pmid:9325095	complex(p(HGNC:ACHE), p(HGNC:APP, frag("672_713"))) increases p(HGNC:APP, frag("672_713"))
pmid:15709485	complex(p(HGNC:ACHE), p(HGNC:APP, frag("672_713"))) increases bp(GOBP:"neuron death")
pmid:15544503	p(HGNC:APP, frag("672_713")) association p(HGNC:ACHE)
pmid:22431227	p(HGNC:APP, frag("672_713")) association act(p(HGNC:ACHE))
pmid:12788508	p(HGNC:APP, frag("672_713")) increases act(a(MESH:D017628))
pmid:15688347	p(HGNC:APP, frag("672_713")) increases act(a(MESH:D017628))
pmid:20847424	p(HGNC:APP, frag("672_713")) increases bp(GOBP:memory)
pmid:20847424	p(HGNC:APP, frag("672_713")) increases bp(GOBP:memory)
pmid:20847424	p(HGNC:APP, frag("672_713")) increases act(p(HGNC:CHRNA1))
pmid:20847424	p(HGNC:APP, frag("672_713")) increases bp(GOBP:"positive regulation of synaptic plasticity")
pmid:20847424	p(HGNC:APP, frag("672_713")) increases a(CHEBI:"glutamate(2-)")
pmid:12788508	p(HGNC:APP, frag("672_713")) decreases p(MGI:Chat)
pmid:12788508	p(HGNC:APP, frag("672_713")) decreases bp(GOBP:"positive regulation of synaptic transmission, cholinergic")
pmid:16696577	p(HGNC:APP, frag("672_713")) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:15177383	p(HGNC:APP, frag("672_713")) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:14699432	p(HGNC:APP, frag("672_713")) biomarkerFor path(MESHD:"Alzheimer Disease")
pmid:18584921	p(HGNC:APP, frag("672_713")) association path(MESHD:"Alzheimer Disease")
pmid:16216580	p(HGNC:APP, frag("672_713")) biomarkerFor path(MESHD:"Alzheimer Disease")
pmid:24332564	p(HGNC:APP, frag("672_713")) increases path(MESHD:"Alzheimer Disease")
pmid:23577068	p(HGNC:APP, frag("672_713")) association path(MESHD:"Alzheimer Disease")
pmid:15295589	p(HGNC:APP, frag("672_713")) decreases bp(GOBP:"mitochondrial calcium ion homeostasis")
pmid:15295589	p(HGNC:APP, frag("672_713")) decreases bp(GOBP:"electron transport chain")
pmid:15295589	p(HGNC:APP, frag("672_713")) increases a(CHEBI:superoxide)
pmid:15295589	p(HGNC:APP, frag("672_713")) decreases a(CHEBI:ATP)
pmid:22523685	p(HGNC:APP, frag("672_713")) decreases a(CHEBI:ATP)
pmid:15232608	p(HGNC:APP, frag("672_713")) increases a(CHEBI:"nitric oxide")
pmid:24948534	p(HGNC:APP, frag("672_713")) increases tloc(a(CHEBI:"nitric oxide"), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:10830966	p(HGNC:APP, frag("672_713")) increases rxn(reactants(p(HGNC:CDK5R1)), products(p(HBP:"CDK5R1 p25")))
pmid:20597865	p(HGNC:APP, frag("672_713")) positiveCorrelation g(HGNC:CTSD, var("c.224C>T"))
pmid:18675468	p(HGNC:APP, frag("672_713")) increases tloc(a(CHEBI:"phosphatidyl-L-serine"), fromLoc(MESHCS:"Cell Membrane"), toLoc(MESHCS:"Cell Surface Extensions"))
pmid:18675468	p(HGNC:APP, frag("672_713")) directlyDecreases act(p(HGNC:ADAM10), ma(pep))
pmid:18675468	p(HGNC:APP, frag("672_713")) directlyDecreases a(HBP:"sAPP-alpha")
pmid:15910549	p(HGNC:APP, frag("672_713")) decreases a(CHEBI:"copper(0)")
pmid:22500019	p(HGNC:APP, frag("672_713")) increases a(CHEBI:"calcium(2+)")
pmid:22500019	p(HGNC:APP, frag("672_713")) increases a(CHEBI:"3',5'-cyclic AMP")
pmid:22500019	p(HGNC:APP, frag("672_713")) increases act(p(SFAM:"AKT Family"))
pmid:22500019	p(HGNC:APP, frag("672_713")) increases bp(GOBP:"regulation of MAP kinase activity")
pmid:22500019	p(HGNC:APP, frag("672_713")) increases act(p(HGNC:FOS))
pmid:22107728	p(HGNC:APP, frag("672_713")) positiveCorrelation g(DBSNP:rs4646953)
pmid:20847424	p(HGNC:APP, frag("672_713")) increases bp(GOBP:"long-term synaptic potentiation")
pmid:23164821	p(HGNC:APP, frag("672_713")) increases bp(GOBP:"neuron apoptotic process")
pmid:18997293	p(HGNC:APP, frag("672_713")) increases bp(GOBP:"neuron apoptotic process")
pmid:21945540	p(HGNC:APP, frag("672_713")) increases bp(GOBP:"neuron apoptotic process")
pmid:24269024	p(HGNC:APP, frag("672_713")) increases p(HGNC:CYSLTR1)
pmid:24332564	p(HGNC:APP, frag("672_713")) association p(HGNC:NOS3)
pmid:22431227	p(HGNC:APP, frag("672_713")) decreases p(HGNC:NOS3)
pmid:24332564	p(HGNC:APP, frag("672_713")) decreases p(HGNC:NOS3)
pmid:24332564	p(HGNC:APP, frag("672_713")) association p(HGNC:PIN1)
pmid:21193044	p(HGNC:APP, frag("672_713")) increases p(HGNC:EDN1)
pmid:21193044	p(HGNC:APP, frag("672_713")) decreases bp(MESHPP:"Cerebrovascular Circulation")
pmid:21193044	p(HGNC:APP, frag("672_713")) increases p(HGNC:ECE2)
pmid:24879954	p(HGNC:APP, frag("672_713")) increases p(MGI:Cysltr1)
pmid:20052565	p(HGNC:APP, frag("672_713")) association a(CHEBI:"galactosylceramide sulfate")
pmid:15688347	p(HGNC:APP, frag("672_713")) association p(HGNC:"HLA-DQB1")
pmid:21177868	p(HGNC:APP, frag("672_713")) decreases p(HGNC:CDH2)
pmid:21177868	p(HGNC:APP, frag("672_713")) increases p(HGNC:MAPK14, pmod(Ph))
pmid:21177868	p(HGNC:APP, frag("672_713")) increases p(HGNC:MAPT, pmod(Ph))
pmid:19889624	p(HGNC:APP, frag("672_713")) increases p(HGNC:EIF2AK2, pmod(Ph))
pmid:19889624	p(HGNC:APP, frag("672_713")) increases p(HGNC:FADD, pmod(Ph))
pmid:18813209	p(HGNC:APP, frag("672_713")) decreases p(HGNC:STAT3)
pmid:2190106	p(HGNC:APP, frag("672_713")) association p(HGNC:SERPINA3)
pmid:20847424	p(HGNC:APP, frag("672_713")) association act(a(MESHC:"Ion Channels"))
pmid:20847424	p(HGNC:APP, frag("672_713")) decreases bp(HP:"chemical synaptic transmission")
pmid:20847424	p(HGNC:APP, frag("672_713")) increases p(HGNC:GSK3B, pmod(Ph, Ser, 9))
pmid:19245828	p(HGNC:APP, frag("672_713")) increases a(CHEBI:"reactive oxygen species")
pmid:16484331	p(HGNC:APP, frag("672_713")) increases a(CHEBI:"reactive oxygen species")
pmid:24357806	p(HGNC:APP, frag("672_713")) increases a(CHEBI:"reactive oxygen species")
pmid:19245828	p(HGNC:APP, frag("672_713")) increases a(CHEBI:"reactive oxygen species")
pmid:23164821	p(HGNC:APP, frag("672_713")) increases p(HGNC:DKK1)
pmid:23164821	p(HGNC:APP, frag("672_713")) increases p(HGNC:DKK1)
pmid:23164821	p(HGNC:APP, frag("672_713")) negativeCorrelation deg(p(HGNC:DKK1))
pmid:23164821	p(HGNC:APP, frag("672_713")) increases p(HGNC:DKK1)
pmid:23164821	p(HGNC:APP, frag("672_713")) increases p(HGNC:DKK1)
pmid:23164821	p(HGNC:APP, frag("672_713")) increases bp(GOBP:"Wnt signaling pathway, planar cell polarity pathway")
pmid:26402072	p(HGNC:APP, frag("672_713")) association p(HGNC:TIMP1)
pmid:26402072	p(HGNC:APP, frag("672_713")) association p(SFAM:"MMP Family")
pmid:23164821	p(HGNC:APP, frag("672_713")) increases bp(GOBP:"neuron death")
pmid: 22646481	p(HGNC:APP, frag("672_713")) association bp(GOBP:"neuron death")
pmid:18813209	act(p(HGNC:APP, frag("672_713"))) increases bp(GOBP:"neuron death")
pmid:23164821	p(HGNC:APP, frag("672_713")) positiveCorrelation p(HGNC:CLU)
pmid:23164821	p(HGNC:APP, frag("672_713")) increases p(HGNC:CLU, loc(MESHCS:Cytosol))
pmid:23164821	p(HGNC:APP, frag("672_713")) decreases tloc(p(HGNC:CLU), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:23164821	p(HGNC:APP, frag("672_713")) increases p(HGNC:CLU, loc(MESHCS:Cytosol))
pmid:23164821	p(HGNC:APP, frag("672_713")) decreases tloc(p(HGNC:CLU), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid: 21543606	p(HGNC:APP, frag("672_713")) association p(HGNC:CLU)
pmid:23164821	p(HGNC:APP, frag("672_713")) positiveCorrelation p(HGNC:EGR1)
pmid:23164821	p(HGNC:APP, frag("672_713")) positiveCorrelation p(HGNC:NAB2)
pmid:23164821	p(HGNC:APP, frag("672_713")) positiveCorrelation p(HGNC:KLF10)
pmid:20847424	p(HGNC:APP, frag("672_713")) directlyDecreases act(p(HGNC:HSD17B10), ma(cat))
pmid:20847424	p(HGNC:APP, frag("672_713")) decreases a(CHEBI:"iron(3+)")
pmid:20847424	p(HGNC:APP, frag("672_713")) decreases a(CHEBI:"copper(2+)")
pmid:20847424	p(HGNC:APP, frag("672_713")) decreases bp(GOBP:"regulation of glutathione peroxidase activity")
pmid:21945540	p(HGNC:APP, frag("672_713")) increases act(p(HGNC:GSK3B))
pmid:18615183	p(HGNC:APP, frag("672_713")) increases p(HGNC:IL12B)
pmid:18615183	p(HGNC:APP, frag("672_713")) increases p(HGNC:IL23A)
pmid:18615183	p(HGNC:APP, frag("672_713")) increases p(HGNC:CD14)
pmid:18615183	p(HGNC:APP, frag("672_713")) increases p(HGNC:MYD88)
pmid:18615183	p(HGNC:APP, frag("672_713")) increases p(HGNC:TLR2)
pmid:24512768	p(HGNC:APP, frag("672_713")) increases path(MESHD:Inflammation)
pmid:24512768	p(HGNC:APP, frag("672_713")) increases bp(HBP:neurotoxicity)
pmid:11755016	p(HGNC:APP, frag("672_713")) increases bp(GOBP:"microglial cell activation")
pmid:19519303	p(HGNC:APP, frag("672_713")) positiveCorrelation path(MESHD:"Glucose Intolerance")
pmid:19519303	p(HGNC:APP, frag("672_713")) association bp(GOBP:"regulation of insulin-like growth factor receptor signaling pathway")
pmid:16399206	p(HGNC:APP, frag("672_713")) negativeCorrelation act(p(HGNC:IDE))
pmid:18411275	deg(p(HGNC:APP, frag("672_713"))) association p(HGNC:IDE)
pmid:16399206	p(HGNC:APP, frag("672_713")) decreases complex(p(HGNC:INS), p(HGNC:INSR))
pmid:20061608	p(HGNC:APP, frag("672_713")) association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:23557940	p(HGNC:APP, frag("672_713")) negativeCorrelation act(p(HGNC:IGF1))
pmid:20847424	p(HGNC:APP, frag("672_713")) increases act(p(HGNC:IGF1))
pmid:23557940	p(HGNC:APP, frag("672_713")) positiveCorrelation bp(MESHPP:"Insulin Resistance")
pmid:20847424	p(HGNC:APP, frag("672_713")) increases act(p(HGNC:IRS1, pmod(Ph, Thr)))
pmid:20847424	p(HGNC:APP, frag("672_713")) increases act(p(HGNC:IRS2, pmod(Ph, Thr)))
pmid:20847424	p(HGNC:APP, frag("672_713")) increases act(p(HGNC:SHC1, pmod(Ph, Thr)))
pmid:20847424	p(HGNC:APP, frag("672_713")) increases act(p(HGNC:SHC2, pmod(Ph, Thr)))
pmid:20847424	p(HGNC:APP, frag("672_713")) increases act(p(HGNC:SHC3, pmod(Ph, Thr)))
pmid:20847424	p(HGNC:APP, frag("672_713")) increases act(p(HGNC:SHC4, pmod(Ph, Thr)))
pmid:20049331	p(HGNC:APP, frag("672_713")) directlyDecreases tloc(p(HGNC:LDLR), fromLoc(GOCC:intracellular), toLoc(MESHCS:"Cell Membrane"))
pmid:21676498	p(HGNC:APP, frag("672_713")) association p(HGNC:APOE)
pmid:18549781	p(HGNC:APP, frag("672_713")) association p(HGNC:APOE)
pmid:14970312	p(HGNC:APP, frag("672_713")) increases a(CHEBI:cholesterol)
pmid:20061608	p(HGNC:APP, frag("672_713")) positiveCorrelation a(MESHC:"Lipoproteins, LDL")
pmid:20061608	p(HGNC:APP, frag("672_713")) positiveCorrelation a(CHEBI:triglyceride)
pmid:17694066	deg(p(HGNC:APP, frag("672_713"))) association p(HGNC:LRP1)
pmid:22383525	tloc(p(HGNC:APP, frag("672_713")), fromLoc(MESHCS:"COP-Coated Vesicles"), toLoc(MESHCS:Lysosomes)) increases deg(p(HGNC:APP, frag("672_713")))
pmid: 22646481	p(HGNC:APP, frag("672_713")) decreases bp(GOBP:"maintenance of synapse structure")
pmid: 22646481	p(HGNC:APP, frag("672_713")) association act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits"))
pmid: 22646481	p(HGNC:APP, frag("672_713")) association bp(GOBP:"cholesterol homeostasis")
pmid:21244351	p(HGNC:APP, frag("672_713")) increases a(MESH:D005971)
pmid: 21543606	p(HGNC:APP, frag("672_713")) decreases a(MESH:D009836)
pmid:14970312	p(HGNC:APP, frag("672_713")) increases bp(MESHPP:"Oxidative Stress")
pmid:14970312	p(HGNC:APP, frag("672_713")) increases bp(MESHPP:"Oxidative Stress")
pmid:14970312	p(HGNC:APP, frag("672_713")) increases a(CHEBI:ceramide)
pmid:14970312	p(HGNC:APP, frag("672_713")) association bp(GOBP:"regulation of lipid metabolic process")
pmid:24332564	p(HGNC:APP, frag("672_713")) increases a(CHEBI:"amyloid-beta")
pmid:24948534	p(HGNC:APP, frag("672_713")) association tloc(p(HGNC:CASR), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:22431227	p(HGNC:APP, frag("672_713")) decreases a(CHEBI:nitrite)
pmid:22431227	p(HGNC:APP, frag("672_713")) decreases a(CHEBI:nitrate)
pmid:8879214	p(HGNC:APP, frag("672_713")) increases p(MGI:Nos2)
pmid:22227962	deg(p(HGNC:APP, frag("672_713"))) negativeCorrelation p(HGNC:NOS2)
pmid:22382662	p(HGNC:APP, frag("672_713")) negativeCorrelation p(HGNC:SYVN1)
pmid:23022416	p(HGNC:APP, frag("672_713")) negativeCorrelation g(DBSNP:rs3818361)
pmid:21994399	p(HGNC:APP, frag("672_713")) negativeCorrelation m(HGNC:MIR137)
pmid:21994399	p(HGNC:APP, frag("672_713")) negativeCorrelation m(HGNC:MIR181C)
pmid:21994399	p(HGNC:APP, frag("672_713")) negativeCorrelation m(HGNC:"MIR9-1")
pmid:21994399	p(HGNC:APP, frag("672_713")) negativeCorrelation m(HGNC:MIR29A)
pmid:12639958	p(HGNC:APP, frag("672_713")) positiveCorrelation p(HGNC:PSENEN)
pmid:21396986	deg(p(HGNC:APP, frag("672_713"))) association p(HGNC:DHCR24)
pmid:22013558	p(HGNC:APP, frag("672_713")) association a(MESHC:cerebrolysin)
pmid:20042680	p(HGNC:APP, frag("672_713")) decreases bp(MESHPP:"Long-Term Potentiation")
pmid:24918635	p(HGNC:APP, frag("672_713")) negativeCorrelation p(HGNC:MMP9)
pmid:21718295	p(HGNC:APP, frag("672_713")) negativeCorrelation p(HGNC:ABCB1)
pmid:21718295	p(HGNC:APP, frag("672_713")) negativeCorrelation p(HGNC:ABCB1)
pmid:10672313	deg(p(HGNC:APP, frag("672_713"))) association p(HGNC:MMP3)
pmid:24126163	p(HGNC:APP, frag("672_713")) negativeCorrelation p(HGNC:PLAT)
pmid:23181169	p(HGNC:APP, frag("672_713")) negativeCorrelation p(HGNC:ABCG2)
pmid:24987467	p(HGNC:APP, frag("672_713")) negativeCorrelation p(HGNC:ACE)
pmid:24879954	act(p(HGNC:APP, frag("672_713"))) decreases p(MGI:Bcl2)
pmid:24879954	act(p(HGNC:APP, frag("672_713"))) increases act(p(MGI:Casp3))
pmid:18549781	p(HGNC:APP, frag("672_713")) increases complex(p(HGNC:APOE), p(HGNC:APP, frag("672_713")))
pmid:20224908	deg(p(HGNC:APP, frag("672_713"))) association p(HGNC:PADI2)
pmid:19541956	p(HGNC:APP, frag("672_713")) increases act(a(MESH:D022142))
pmid:19541956	p(HGNC:APP, frag("672_713")) increases bp(GOBP:"hormone secretion")
pmid:20847424	p(HGNC:APP, frag("672_713")) association bp(GOBP:"cholesterol transport")
pmid:17182778	p(HGNC:APP, frag("672_713")) negativeCorrelation p(HGNC:RTN4)
pmid:16887805	p(HGNC:APP, frag("672_713")) decreases act(complex(GOCC:"respiratory chain complex IV"))
pmid:23237322	p(HGNC:APP, frag("672_713")) association p(HGNC:NOTCH1)
pmid:22523685	p(HGNC:APP, frag("672_713")) increases bp(GOBP:"response to oxidative stress")
pmid:22523685	p(HGNC:APP, frag("672_713")) increases bp(GOBP:"mitochondrial calcium ion transport")
pmid:24357806	p(HGNC:APP, frag("672_713")) increases p(HGNC:IL1B)
pmid:18675468	p(HGNC:APP, frag("672_713")) directlyDecreases bp(GOBP:"calcium ion import")
pmid:18675468	p(HGNC:APP, frag("672_713")) directlyDecreases bp(GOBP:"calcium ion homeostasis")
pmid:22078238	p(HGNC:APP, frag("672_713")) negativeCorrelation p(HGNC:GAL)
pmid:21156028	deg(p(HGNC:APP)) increases p(HGNC:APP, frag("672_713"))
pmid:10605825	deg(p(HGNC:APP)) increases p(HGNC:APP, frag("672_713"))
pmid:10605825	deg(p(HGNC:APP)) increases p(HGNC:APP, frag("672_713"))
pmid:20049331	p(HGNC:APP) increases p(HGNC:APP, frag("672_713"))
pmid:26996954	p(HGNC:APP) decreases p(HGNC:APP, frag("672_713"))
pmid:22156573	tloc(p(HGNC:APP)) decreases p(HGNC:APP, frag("672_713"))
pmid:17709753	p(HGNC:APP) increases act(p(HGNC:SLC5A7))
pmid:17709753	p(HGNC:APP) regulates act(p(HGNC:SLC5A7), ma(tport))
pmid:21156028	deg(p(HGNC:APP)) increases p(HGNC:APP, frag("672_711"))
pmid:22711829	tloc(p(HGNC:APP), fromLoc(MESHCS:Endosomes), toLoc(MESHCS:"trans-Golgi Network")) increases p(HGNC:APP, frag("672_711"))
pmid:22382662	deg(p(HGNC:APP)) positiveCorrelation p(HGNC:APP, pmod(Ub))
pmid:15364413	p(HGNC:APP) association p(HGNC:KLC1)
pmid:25394182	p(HGNC:APP) association p(HGNC:KLC1)
pmid:22434822	act(p(HGNC:APP), ma(tport)) association p(HGNC:KLC1)
pmid:15295589	p(HGNC:APP) decreases a(CHEBI:ATP)
pmid:22523685	p(HGNC:APP) decreases a(CHEBI:ATP)
pmid:7523115	deg(p(HGNC:APP)) association act(p(HGNC:CTSD), ma(pep))
pmid:22523685	p(HGNC:APP) decreases bp(GOBP:"electron transport chain")
pmid:22523685	p(HGNC:APP) decreases bp(GOBP:"mitochondrial calcium ion homeostasis")
pmid:22523685	p(HGNC:APP) decreases bp(GOBP:"mitochondria-nucleus signaling pathway")
pmid:19619643	p(HGNC:APP) decreases bp(GOBP:"mitochondria-nucleus signaling pathway")
pmid:19619643	p(HGNC:APP) increases bp(GOBP:"mitochondria-nucleus signaling pathway")
pmid:22523685	p(HGNC:APP) increases bp(GOBP:"apoptotic process")
pmid:11744168	p(HGNC:APP) increases bp(GOBP:"apoptotic process")
pmid:22496686	p(HGNC:APP) association bp(GOBP:"chromosome segregation")
pmid:22496686	p(HGNC:APP) association path(MESHD:"Down Syndrome")
pmid:22496686	p(HGNC:APP) association p(SFAM:"MAPK Erk1/2 Family")
pmid:22496686	p(HGNC:APP) association p(SFAM:"MAPK Erk1/2 Family", pmod(Ph))
pmid:22496686	tloc(p(HGNC:APP), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space")) increases a(CHEBI:"amyloid-beta")
pmid:22447723	deg(p(HGNC:APP)) increases a(CHEBI:"amyloid-beta")
pmid:17428983	tloc(p(HGNC:APP), fromLoc(MESHCS:"Cell Surface Extensions"), toLoc(MESHCS:Endosomes)) increases a(CHEBI:"amyloid-beta")
pmid:20847424	tloc(p(HGNC:APP), fromLoc(MESHCS:"Cell Membrane"), toLoc(MESHCS:Endosomes)) increases a(CHEBI:"amyloid-beta")
pmid:17185504	deg(p(HGNC:APP)) increases a(CHEBI:"amyloid-beta")
pmid:11744168	deg(p(HGNC:APP)) increases tloc(a(CHEBI:"amyloid-beta"), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:22434822	tloc(p(HGNC:APP), fromLoc(MESHCS:Axons), toLoc(MESHCS:"Cell Membrane")) decreases a(CHEBI:"amyloid-beta")
pmid:19090990	p(HGNC:APP) increases a(CHEBI:"amyloid-beta")
pmid:19245828	p(HGNC:APP) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:26027813	p(HGNC:APP) increases a(CHEBI:"amyloid-beta")
pmid:22447723	deg(p(HGNC:APP)) association p(HGNC:SLC39A1)
pmid:22429478	deg(p(HGNC:APP)) association complex(p(HGNC:APBB1), p(HGNC:APP), p(HGNC:LRP1))
pmid:22115042	p(HGNC:APP) increases bp(GOBP:"positive regulation of neuron apoptotic process")
pmid:22110360	p(HGNC:APP) association p(HGNC:DYRK1A)
pmid:15910549	p(HGNC:APP) increases a(CHEBI:"copper(1+)")
pmid:22787047	tloc(p(HGNC:APP), fromLoc(MESHCS:"trans-Golgi Network"), toLoc(MESHCS:Endosomes)) association p(HGNC:APBA2, pmod(Ph))
pmid:19885299	deg(p(HGNC:APP)) positiveCorrelation bp(MESHPP:"Oxidative Stress")
pmid:17314098	p(HGNC:APP) association act(p(HGNC:MAPK3))
pmid:17314098	p(HGNC:APP) association act(p(HGNC:MAPK1))
pmid:17314098	p(HGNC:APP) increases path(MESHD:"Alzheimer Disease")
pmid:23167255	p(HGNC:APP) increases path(MESHD:"Alzheimer Disease")
pmid:19462468	p(HGNC:APP) association path(MESHD:"Alzheimer Disease")
pmid:16797788	p(HGNC:APP) association path(MESHD:"Alzheimer Disease")
pmid:17314098	p(HGNC:APP) association path(MESHD:"Alzheimer Disease")
pmid:15686969	p(HGNC:APP) association path(MESHD:"Alzheimer Disease")
pmid:21785276	p(HGNC:APP) association m(HGNC:MIR106A)
pmid:21785276	p(HGNC:APP) association m(HGNC:MIR520C)
pmid:24919190	p(HGNC:APP) decreases p(HGNC:FOS)
pmid:17691220	p(HGNC:APP) association a(CHEBI:rivastigmine)
pmid:16624814	deg(p(HGNC:APP)) positiveCorrelation p(HGNC:ADAM10)
pmid:11523796	tloc(p(HGNC:APP), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space")) association complex(p(HGNC:APOE), p(HGNC:APP))
pmid:20052565	p(HGNC:APP) association a(CHEBI:"galactosylceramide sulfate")
pmid:11553277	p(HGNC:APP) association a(MESH:D001253)
pmid:11744168	p(HGNC:APP) increases p(HGNC:BACE1)
pmid:18410513	p(HGNC:APP) association path(MESHD:Hypercholesterolemia)
pmid:17047360	p(HGNC:APP) association p(HGNC:SPAG9)
pmid:18415033	p(HGNC:APP) association p(HGNC:APOE)
pmid:12425945	p(HGNC:APP) increases act(p(HGNC:CASP3))
pmid:12425945	p(HGNC:APP) increases a(CHEBI:"calcium(2+)")
pmid:12425945	p(HGNC:APP) increases act(p(HGNC:CAPN2))
pmid:14557245	p(HGNC:APP) increases p(HGNC:NAE1)
pmid:22156573	tloc(p(HGNC:APP)) decreases complex(p(HGNC:APBB1), p(HGNC:APP), p(HGNC:KLC1))
pmid:19515914	p(HGNC:APP) increases bp(GOBP:"cell adhesion")
pmid:18650430	p(HGNC:APP) increases bp(GOBP:"cell adhesion")
pmid:19515914	p(HGNC:APP) increases bp(GOBP:"cell migration")
pmid:19515914	p(HGNC:APP) increases bp(GOBP:"neuron projection development")
pmid:19515914	p(HGNC:APP) association bp(GOBP:"neuron projection development")
pmid:22349563	p(HGNC:APP) association bp(GOBP:"neuron projection development")
pmid:19515914	p(HGNC:APP) association p(HGNC:RELN)
pmid:19515914	p(HGNC:APP) association p(HGNC:DAB1)
pmid:19515914	p(HGNC:APP) association p(HGNC:ITGB1BP1)
pmid:22355794	p(HGNC:APP) association bp(GOBP:"neuron development")
pmid:22355794	p(HGNC:APP) association bp(GOBP:"cell-matrix adhesion")
pmid:22355794	p(HGNC:APP) association bp(GOBP:"cell-cell adhesion")
pmid:22355794	p(HGNC:APP) association bp(GOBP:"regulation of long-term synaptic potentiation")
pmid:22355794	p(HGNC:APP) association path(MESH:D065852)
pmid:22349563	p(HGNC:APP) association bp(GOBP:neurogenesis)
pmid:22349563	p(HGNC:APP) association bp(GOBP:"regulation of neuron migration")
pmid:22349563	p(HGNC:APP) association bp(GOBP:"neuron cell-cell adhesion")
pmid:18650430	p(HGNC:APP) association bp(GOBP:"cytokine metabolic process")
pmid:19090990	p(HGNC:APP) decreases bp(GOBP:"regulation of cellular response to oxidative stress")
pmid:24290604	p(HGNC:APP) association p(HGNC:TLR4)
pmid:24290604	p(HGNC:APP) association p(HGNC:NFKB1)
pmid:24919190	p(HGNC:APP) decreases p(HGNC:EGR1)
pmid:24919190	p(HGNC:APP) decreases p(HGNC:BDNF)
pmid:24919190	p(HGNC:APP) decreases p(HGNC:ARC)
pmid:25570489	p(HGNC:APP) association a(NIFT:"Cerebral atrophy")
pmid:25678559	p(HGNC:APP) increases a(NIFT:"Hippocampal Formation")
pmid:25678559	p(HGNC:APP) negativeCorrelation a(NIFT:"Hippocampus volume")
pmid:25678559	p(HGNC:APP) negativeCorrelation a(NIFT:"Mini mental state exam")
pmid:25678559	p(HGNC:APP) positiveCorrelation a(NIFT:"Clinical dementia rating")
pmid:20065247	p(HGNC:APP) positiveCorrelation a(NIFT:"Hippocampal atrophy")
pmid:24919190	p(HGNC:APP) decreases act(p(SFAM:"CREB Family"), ma(tscript))
pmid:22496686	p(HGNC:APP) increases p(HGNC:KAT5, pmod(Ph))
pmid:20100581	p(HGNC:APP) association bp(HP:Neurodegeneration)
pmid:17095583	p(HGNC:APP) increases p(HGNC:GRIN2B, pmod(Ph))
pmid:21034527	act(p(HGNC:APP)) increases act(p(HGNC:GSK3B))
pmid:22496686	deg(p(HGNC:APP)) association p(HGNC:LRP8)
pmid:10797543	deg(p(HGNC:APP)) association p(HGNC:LRP1)
pmid:15772078	p(HGNC:APP) association p(HGNC:LRP1)
pmid:26996954	p(HGNC:APP) association p(HGNC:SORL1)
pmid:22434822	act(p(HGNC:APP), ma(tport)) association p(HGNC:CLSTN1)
pmid:23312564	p(HGNC:APP) association a(CHEBI:mifepristone)
pmid:16452662	p(HGNC:APP) increases complex(p(HGNC:APP), p(HGNC:RTN4R))
pmid:16452662	p(HGNC:APP) association p(HGNC:RTN4R)
pmid:21214928	tloc(p(HGNC:APP), fromLoc(MESHCS:"trans-Golgi Network"), toLoc(MESHCS:"Cell Surface Extensions")) decreases rxn(reactants(p(HGNC:APP)), products(p(HGNC:APP, frag("672_713"))))
pmid:21214928	tloc(p(HGNC:APP), fromLoc(MESHCS:"trans-Golgi Network"), toLoc(MESHCS:"Cell Surface Extensions")) increases rxn(reactants(p(HGNC:APP)), products(a(HBP:"sAPP-alpha")))
pmid:20847424	act(p(HGNC:APP), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(a(HBP:"sAPP-alpha")))
pmid:19619643	p(HGNC:APP) increases bp(GOBP:"cell-cell adhesion involved in synapse maturation")
pmid:22496686	p(HGNC:APP) association p(HGNC:MAPK8IP2)
pmid:22122372	tloc(p(HGNC:APP)) association complex(p(HGNC:APBA1), p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site"))
pmid:18299393	complex(p(HGNC:ACHE), p(HGNC:PSEN1)) regulates bp(GOBP:glycosylation)
pmid:19276086	tloc(p(HGNC:PSEN1), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space")) increases act(complex(SCOMP:"gamma Secretase Complex"), ma(pep))
pmid:22496686	p(HGNC:PSEN1) association bp(GOBP:"chromosome segregation")
pmid:17314098	p(HGNC:PSEN1) association path(MESHD:"Alzheimer Disease")
pmid:22382662	p(HGNC:PSEN1) association path(MESHD:"Alzheimer Disease")
pmid:22115042	act(p(HGNC:PSEN1)) increases p(HGNC:APP)
pmid:16973241	act(p(HGNC:PSEN1)) directlyIncreases deg(p(HGNC:APP))
pmid:12684521	p(HGNC:PSEN1) increases deg(p(HGNC:APP))
pmid:22115042	act(p(HGNC:PSEN1)) increases bp(GOBP:"positive regulation of neuron apoptotic process")
pmid:12374741	act(p(HGNC:PSEN1), ma(kin)) increases a(CHEBI:"amyloid-beta")
pmid:11814648	p(HGNC:PSEN1) increases a(CHEBI:"amyloid-beta")
pmid:17115048	p(HGNC:PSEN1) increases a(CHEBI:"amyloid-beta")
pmid:10801777	p(HGNC:PSEN1) increases a(CHEBI:"amyloid-beta")
pmid:10670705	p(HGNC:PSEN1) increases a(CHEBI:"amyloid-beta")
pmid:9344855	p(HGNC:PSEN1) increases a(CHEBI:"amyloid-beta")
pmid:9843412	p(HGNC:PSEN1) increases a(CHEBI:"amyloid-beta")
pmid:10653282	p(HGNC:PSEN1) increases a(CHEBI:"amyloid-beta")
pmid:14980721	p(HGNC:PSEN1) increases a(CHEBI:"amyloid-beta")
pmid:14993906	p(HGNC:PSEN1) increases a(CHEBI:"amyloid-beta")
pmid:10037471	p(HGNC:PSEN1) increases a(CHEBI:"amyloid-beta")
pmid:12147673	p(HGNC:PSEN1) increases a(CHEBI:"amyloid-beta")
pmid:12603837	p(HGNC:PSEN1) increases a(CHEBI:"amyloid-beta")
pmid:16814287	p(HGNC:PSEN1) increases p(HGNC:GSK3B)
PubMed Central:PMC21391	p(HGNC:PSEN1) association p(HGNC:GSK3B)
pmid:17389597	p(HGNC:PSEN1) increases complex(p(HGNC:CDH2), p(HGNC:CTNNB1), p(HGNC:PSEN1))
pmid:17389597	tloc(p(HGNC:PSEN1), fromLoc(GOCC:intracellular), toLoc(GOCC:"cell surface")) positiveCorrelation complex(p(HGNC:CDH2), p(HGNC:PSEN1))
pmid:22496686	p(HGNC:PSEN1) increases deg(p(HGNC:CTNNB1))
pmid:22496686	p(HGNC:PSEN1) association p(HGNC:BCL2)
pmid:22496686	p(HGNC:PSEN1) increases tloc(p(HGNC:CDH2), fromLoc(MESHCS:"Endoplasmic Reticulum"), toLoc(MESHCS:"Cell Membrane"))
pmid:22496686	p(HGNC:PSEN1) association path(MESHD:"Down Syndrome")
pmid:22461631	p(HGNC:PSEN1) decreases act(p(HGNC:NOTCH1))
pmid:10967351	p(HGNC:PSEN1) association bp(GOBP:"Notch signaling pathway")
pmid:22426017	p(HGNC:PSEN1) increases bp(GOBP:"neuron death")
PubMed Central:PMC21391	p(HGNC:PSEN1) association p(HGNC:MAPT)
pmid:14976144	complex(p(HGNC:CDK5), p(HGNC:CDK5R1)) regulates act(p(HGNC:ACHE))
pmid:17160145	complex(p(HGNC:CDK5), p(HGNC:CDK5R1)) association p(HGNC:GSK3B)
pmid:17160145	complex(p(HGNC:CDK5), p(HGNC:CDK5R1)) association p(HGNC:JUN)
pmid:14976144	act(complex(p(HGNC:CDK5), p(HGNC:CDK5R1))) positiveCorrelation a(GOCC:cell)
pmid:14976144	act(complex(p(HGNC:CDK5), p(HGNC:CDK5R1))) increases r(HGNC:INS)
pmid:14976144	complex(p(HGNC:CDK5), p(HGNC:CDK5R1)) increases p(HGNC:IAPP)
pmid:14976144	act(complex(p(HGNC:CDK5), p(HGNC:CDK5R1))) increases p(HGNC:IAPP)
pmid:14976144	complex(p(HGNC:CDK5), p(HGNC:CDK5R1)) increases complex(GOCC:"plasma lipoprotein particle")
pmid:14976144	act(complex(p(HGNC:CDK5), p(HGNC:CDK5R1))) increases complex(GOCC:"plasma lipoprotein particle")
pmid:14976144	act(complex(p(HGNC:CDK5), p(HGNC:CDK5R1))) increases a(CHEBI:glucose)
pmid:14976144	act(complex(p(HGNC:CDK5), p(HGNC:CDK5R1))) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:15686969	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:11013232	act(p(HGNC:CDK5)) increases p(HGNC:MAPT, pmod(Ph))
pmid:17078951	act(p(HGNC:CDK5)) increases p(HGNC:MAPT, pmod(Ph))
pmid:11181841	act(p(HGNC:CDK5)) increases p(HGNC:MAPT, pmod(Ph))
pmid:19154537	act(p(HGNC:CDK5)) increases p(HGNC:MAPT, pmod(Ph))
pmid:10830966	act(p(HGNC:CDK5), ma(kin)) directlyIncreases p(HGNC:MAPT, pmod(Ph))
pmid:11578751	act(p(HGNC:CDK5), ma(kin)) directlyIncreases p(HGNC:MAPT, pmod(Ph))
pmid:19419557	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:8090222	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:14976144	act(p(HGNC:CDK5)) increases p(HGNC:MAPT, pmod(Ph))
pmid:19519303	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:12428805	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:14673212	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:17120162	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:11013232	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:7704571	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:17965932	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:7669983	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:11054815	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:17078951	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:11181841	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:8282104	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:9565682	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:9089387	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:11943163	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:22874667	p(HGNC:CDK5) association bp(GOBP:"peptidyl-cysteine S-trans-nitrosylation")
pmid:22874667	p(HGNC:CDK5) association bp(GOBP:"peptidyl-cysteine S-trans-nitrosylation")
pmid:21389115	act(p(HGNC:CDK5), ma(kin)) association bp(GOBP:"cell death")
pmid:22874667	act(p(HGNC:CDK5)) increases bp(GOBP:"cell death")
pmid:21389115	act(p(HGNC:CDK5), ma(kin)) association a(CHEBI:"amyloid-beta")
pmid:21389115	act(p(HGNC:CDK5), ma(kin)) association complex(GOCC:"neurofibrillary tangle")
pmid:15686969	act(p(HGNC:CDK5), ma(kin)) association complex(p(HGNC:APBB1), p(HGNC:MAPT))
pmid:10936190	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:APP, pmod(Ph))
pmid:22874667	act(p(HGNC:CDK5)) increases bp(HP:"Abnormality of mitochondrial metabolism")
pmid:15676027	act(p(HGNC:CDK5)) increases p(HGNC:DPYSL2, pmod(Ph))
pmid:12428805	act(p(HGNC:CDK5)) regulates bp(GOBP:"axonal transport")
pmid:10998059	act(p(HGNC:CDK5)) negativeCorrelation a(CHEBI:alsterpaullone)
pmid:10998059	act(p(HGNC:CDK5)) increases p(HGNC:PPP1R1B, pmod(Ph))
pmid:22874667	p(HGNC:CDK5) increases p(HGNC:NOS1, pmod(Ph))
pmid:22874667	p(HGNC:CDK5) decreases act(p(HGNC:NOS1))
pmid:10830966	act(p(HGNC:CDK5), ma(kin)) decreases bp(GOBP:"cytoskeleton organization")
pmid:10830966	act(p(HGNC:CDK5), ma(kin)) increases bp(GOBP:"neuron apoptotic process")
pmid:8090222	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:NEFL, pmod(Ph))
pmid:14976144	act(p(HGNC:CDK5)) association path(MESHD:"Nerve Degeneration")
pmid:23362255	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser))
pmid:23362255	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr))
pmid:21489990	p(HGNC:CDK5) increases p(HGNC:PPP1CA, pmod(Ph))
pmid:21489990	p(HGNC:CDK5) increases p(HGNC:MAPT, pmod(Ph, Ser, 262))
pmid:12387894	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 199))
pmid:12387894	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 202))
pmid:12387894	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 214))
pmid:12387894	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 235))
pmid:12387894	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:11181841	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:12387894	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 404))
pmid:11181841	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 404))
pmid:12387894	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 181))
pmid:11181841	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 181))
pmid:12387894	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 205))
pmid:11181841	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 205))
pmid:12387894	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 212))
pmid:11181841	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 212))
pmid:12387894	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 217))
pmid:11181841	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 217))
pmid:12387894	act(p(HGNC:CDK5), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 231))
pmid:14673212	act(p(HGNC:CDK5), ma(kin)) association path(MESHD:"Alzheimer Disease")
pmid:11181841	p(HGNC:CDK5) association path(MESHD:"Alzheimer Disease")
pmid:14673212	act(p(HGNC:CDK5), ma(kin)) association path(MESHD:"Amyotrophic Lateral Sclerosis")
pmid:14976144	act(p(HGNC:CDK5R1)) positiveCorrelation a(GOCC:cell)
pmid:14976144	act(p(HGNC:CDK5R1)) increases act(p(HGNC:CDK5))
pmid:17160145	act(p(HGNC:CDK5R1), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:19272425	act(p(HGNC:CHRNA3)) increases a(CHEBI:"gamma-aminobutyric acid")
pmid:19272425	act(p(HGNC:CHRNA3)) increases a(CHEBI:"glutamate(1-)")
pmid:16426583	p(HGNC:CHRNA3) association a(CHEBI:acetylcholine)
pmid:15474976	p(HGNC:CHRNA3) positiveCorrelation bp(HBP:neuroinflammation)
pmid:19272425	act(p(HGNC:CHRNB4)) increases a(CHEBI:"glutamate(1-)")
pmid:16426583	p(HGNC:CHRNB4) association a(CHEBI:acetylcholine)
pmid:19885299	g(HGNC:CHAT) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:26792551	m(HGNC:MIR132) increases bp(GOBP:"synaptic transmission, cholinergic")
pmid:26792551	m(HGNC:MIR132) positiveCorrelation p(HGNC:CHAT)
pmid:22720189	m(HGNC:MIR132) association p(HGNC:MAPT, pmod(Ph))
pmid:22720189	m(HGNC:MIR132) association bp(MESHPP:"Cell Survival")
pmid:22720189	m(HGNC:MIR132) association bp(MESHPP:"Cell Physiological Phenomena")
pmid:22445674	act(p(HGNC:BCHE)) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:17096857	p(HGNC:BCHE) association path(MESHD:"Alzheimer Disease")
pmid:17096857	p(HGNC:BCHE) association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:17096857	p(HGNC:BCHE) regulates bp(MESHPP:"Insulin Resistance")
pmid:17096857	p(HGNC:BCHE) regulates bp(GOBP:"lipid metabolic process")
pmid:17553629	p(HGNC:BCHE) decreases a(CHEBI:acetylcholine)
pmid:23759148	act(p(HGNC:BCHE)) positiveCorrelation act(a(MESH:D001253))
pmid:23759148	p(HGNC:BCHE) association p(HGNC:GFAP)
pmid:23759148	p(HGNC:BCHE) association p(HGNC:S100B)
pmid:23759148	p(HGNC:BCHE) association p(HGNC:IL1B)
pmid:23759148	p(HGNC:BCHE) association p(HGNC:TNF)
pmid:26792551	p(HGNC:CHAT) positiveCorrelation m(HGNC:MIR132)
pmid:26792551	p(HGNC:CHAT) positiveCorrelation p(HGNC:EGR1)
pmid:9775403	p(HGNC:CHRM3) increases bp(PTS:"APP processing pathway")
pmid:19272425	act(p(HGNC:CHRNA10)) increases a(CHEBI:"gamma-aminobutyric acid")
pmid:19272425	act(p(HGNC:CHRNA10)) increases a(CHEBI:"glutamate(1-)")
pmid:16426583	p(HGNC:CHRNA10) association a(CHEBI:acetylcholine)
pmid:19272425	act(p(HGNC:CHRNA2)) increases a(CHEBI:"gamma-aminobutyric acid")
pmid:19272425	act(p(HGNC:CHRNA2)) increases a(CHEBI:"glutamate(1-)")
pmid:16426583	p(HGNC:CHRNA2) association a(CHEBI:acetylcholine)
pmid:20847424	act(p(HGNC:CHRNA2)) regulates p(HGNC:APP, frag("672_713"))
pmid:20847424	p(HGNC:CHRNA2) increases bp(GOBP:"calcium ion import")
pmid:19272425	act(p(HGNC:CHRNA4)) increases a(CHEBI:"gamma-aminobutyric acid")
pmid:19272425	act(p(HGNC:CHRNA4)) increases a(CHEBI:"glutamate(1-)")
pmid:16426583	p(HGNC:CHRNA4) association a(CHEBI:acetylcholine)
pmid:20847424	p(HGNC:CHRNA4) increases bp(GOBP:"calcium ion import")
pmid:15474976	p(HGNC:CHRNA4) positiveCorrelation bp(HBP:neuroinflammation)
pmid:12214130	p(HGNC:CHRNA4, var("p.Ser413Leu")) association path(MESHD:"Alzheimer Disease")
pmid:19272425	act(p(HGNC:CHRNA5)) increases a(CHEBI:"gamma-aminobutyric acid")
pmid:19272425	act(p(HGNC:CHRNA5)) increases a(CHEBI:"glutamate(1-)")
pmid:16426583	p(HGNC:CHRNA5) association a(CHEBI:acetylcholine)
pmid:20847424	act(p(HGNC:CHRNA5)) regulates p(HGNC:APP, frag("672_713"))
pmid:20847424	p(HGNC:CHRNA5) increases bp(GOBP:"calcium ion import")
pmid:15474976	p(HGNC:CHRNA5) positiveCorrelation bp(HBP:neuroinflammation)
pmid:19272425	act(p(HGNC:CHRNA6)) increases a(CHEBI:"gamma-aminobutyric acid")
pmid:19272425	act(p(HGNC:CHRNA6)) increases a(CHEBI:"glutamate(1-)")
pmid:16426583	p(HGNC:CHRNA6) association a(CHEBI:acetylcholine)
pmid:20847424	p(HGNC:CHRNA6) increases bp(GOBP:"calcium ion import")
pmid:19272425	act(p(HGNC:CHRNA7)) increases a(CHEBI:"gamma-aminobutyric acid")
pmid:19272425	act(p(HGNC:CHRNA7)) increases a(CHEBI:"glutamate(1-)")
pmid:16426583	p(HGNC:CHRNA7) association a(CHEBI:acetylcholine)
pmid:20847424	p(HGNC:CHRNA7) increases bp(GOBP:"calcium ion import")
pmid:15474976	p(HGNC:CHRNA7) positiveCorrelation bp(HBP:neuroinflammation)
pmid:19272425	act(p(HGNC:CHRNA9)) increases a(CHEBI:"gamma-aminobutyric acid")
pmid:19272425	act(p(HGNC:CHRNA9)) increases a(CHEBI:"glutamate(1-)")
pmid:16426583	p(HGNC:CHRNA9) association a(CHEBI:acetylcholine)
pmid:20847424	act(p(HGNC:CHRNA9)) regulates p(HGNC:APP, frag("672_713"))
pmid:20847424	p(HGNC:CHRNA9) increases bp(GOBP:"calcium ion import")
pmid:19272425	act(p(HGNC:CHRNB2)) increases a(CHEBI:"glutamate(1-)")
pmid:16426583	p(HGNC:CHRNB2) association a(CHEBI:acetylcholine)
pmid:20847424	act(p(HGNC:CHRNB2)) regulates p(HGNC:APP, frag("672_713"))
pmid:20847424	p(HGNC:CHRNB2) increases bp(GOBP:"calcium ion import")
pmid:15474976	p(HGNC:CHRNB2) positiveCorrelation bp(HBP:neuroinflammation)
pmid:12214130	p(HGNC:CHRNB2, var("p.Gln397Pro")) association path(MESHD:"Alzheimer Disease")
pmid:19272425	act(p(HGNC:CHRNB3)) increases a(CHEBI:"glutamate(1-)")
pmid:16426583	p(HGNC:CHRNB3) association a(CHEBI:acetylcholine)
pmid:20847424	p(HGNC:CHRNB3) increases bp(GOBP:"calcium ion import")
pmid:17213958	tloc(p(HGNC:CYCS), fromLoc(MESH:D008928), toLoc(MESHCS:Cytosol)) directlyIncreases act(p(HGNC:ACHE), ma(pep))
pmid:19499146	tloc(p(HGNC:CYCS), fromLoc(MESH:D008928), toLoc(MESHCS:Cytosol)) increases act(p(HGNC:CASP1))
pmid:19499146	tloc(p(HGNC:CYCS), fromLoc(MESH:D008928), toLoc(MESHCS:Cytosol)) increases act(p(HGNC:SCAF11))
pmid:14744432	p(HGNC:CYCS) association p(HGNC:TP53)
pmid:19499146	tloc(p(HGNC:CYCS), fromLoc(MESH:D008928), toLoc(MESHCS:Cytosol)) increases complex(a(CHEBI:ATP), p(HGNC:APAF1), p(HGNC:CYCS))
pmid:26792551	p(HGNC:EGR1) increases bp(GOBP:"synaptic transmission, cholinergic")
pmid:26792551	p(HGNC:EGR1) positiveCorrelation p(HGNC:CHAT)
pmid:27050105	p(HGNC:EGR1) association g(HGNC:APLP2)
pmid:23164821	p(HGNC:EGR1) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:21969301	p(HGNC:EGR1) association path(MESHD:"Alzheimer Disease")
pmid:14585504	p(HGNC:EGR1) association path(MESHD:"Alzheimer Disease")
pmid:23164821	p(HGNC:EGR1) increases p(HGNC:MAPT, pmod(Ph))
pmid:21489990	p(HGNC:EGR1) association p(HGNC:MAPT, pmod(Ph))
pmid:23164821	p(HGNC:EGR1) increases p(HGNC:MAPT, pmod(Ph))
pmid:23164821	p(HGNC:EGR1) increases p(HGNC:MAPT, pmod(Ph))
pmid:23164821	p(HGNC:EGR1) positiveCorrelation p(HGNC:APP, frag("672_713"))
pmid:23164821	p(HGNC:EGR1) increases bp(GOBP:"neuron death")
pmid:19909279	p(HGNC:EGR1) association bp(GOBP:"regulation of neuronal synaptic plasticity")
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRA1)
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRA2)
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRA3)
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRA4)
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRA5)
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRA6)
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRB1)
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRB2)
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRB3)
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRG1)
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRG2)
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRG3)
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRD)
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRE)
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRP)
pmid:19909279	p(HGNC:EGR1) regulates p(HGNC:GABRQ)
pmid:19909279	p(HGNC:EGR1) regulates p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")
pmid:19909279	p(HGNC:EGR1) regulates complex(GOCC:"proteasome complex")
pmid:21969301	p(HGNC:EGR1) increases a(MESHC:"Glatiramer Acetate")
pmid:14585504	p(HGNC:EGR1) increases p(HGNC:PSEN2)
pmid:21969301	p(HGNC:EGR1) negativeCorrelation path(MESH:D058225)
pmid:21969301	p(HGNC:EGR1) association path(MESHD:Glaucoma)
pmid:21489990	p(HGNC:EGR1) increases p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:21489990	p(HGNC:EGR1) increases p(HGNC:MAPT, pmod(Ph, Ser, 404))
pmid:21489990	p(HGNC:EGR1) increases p(HGNC:MAPT, pmod(Ph, Ser, 262))
pmid:21489990	p(HGNC:EGR1) increases bp(GOBP:"microtubule depolymerization")
pmid:12769595	p(HGNC:GAL) decreases bp(GOBP:"acetylcholine secretion")
pmid:12769595	p(HGNC:GAL) association bp(GOBP:"negative regulation of synaptic transmission, cholinergic")
pmid:12769595	p(HGNC:GAL) association bp(GOBP:"learning or memory")
pmid:12769595	p(HGNC:GAL) decreases bp(GOBP:"negative regulation of insulin secretion involved in cellular response to glucose stimulus")
pmid:22078238	p(HGNC:GAL) negativeCorrelation p(HGNC:MAPT)
pmid:22078238	p(HGNC:GAL) negativeCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:22078238	p(HGNC:GAL) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:23759148	p(HGNC:GFAP) association p(HGNC:BCHE)
pmid:20555131	p(HGNC:GFAP) association bp(GOBP:"inflammatory response")
pmid:21821968	p(HGNC:GRIN2B) increases bp(GOBP:cognition)
pmid:21821968	p(HGNC:GRIN2B) increases bp(GOBP:learning)
pmid:21821968	p(HGNC:GRIN2B) increases bp(GOBP:memory)
pmid:20847424	act(p(HGNC:GRIN2B)) increases a(CHEBI:"amyloid-beta")
pmid:20847424	act(p(HGNC:GRIN2B)) increases a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:GRIN2B) decreases a(GOCC:"excitatory synapse")
pmid:22496686	p(HGNC:GRIN2B) association p(HGNC:LRP8)
pmid:22122372	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:16914869	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:15686969	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:11578751	act(p(HGNC:GSK3B)) directlyIncreases p(HGNC:MAPT, pmod(Ph))
pmid:21156028	p(HGNC:GSK3B) increases p(HGNC:MAPT, pmod(Ph))
pmid:20847424	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:19519303	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:21985244	act(p(HGNC:GSK3B)) directlyIncreases p(HGNC:MAPT, pmod(Ph))
pmid:22718609	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:19429119	p(HGNC:GSK3B) increases p(HGNC:MAPT, pmod(Ph))
pmid:15314261	p(HGNC:GSK3B) increases p(HGNC:MAPT, pmod(Ph))
pmid:7774712	p(HGNC:GSK3B) increases p(HGNC:MAPT, pmod(Ph))
pmid:16973241	act(p(HGNC:GSK3B)) directlyIncreases p(HGNC:MAPT, pmod(Ph))
pmid:17120162	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:11013232	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:7704571	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:17078951	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:10998059	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:21352912	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:20576277	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:20679343	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:7786411	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:8050597	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:11007782	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:10486203	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:8930358	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:11181841	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:15522877	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:12191990	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:19154537	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:18217188	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:19519303	act(p(HGNC:GSK3B)) association p(HGNC:MAPT, pmod(Ph))
pmid:11054815	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:9565682	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:11803455	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:21945540	act(p(HGNC:GSK3B)) increases bp(GOBP:"neuron apoptotic process")
pmid:22122372	act(p(HGNC:GSK3B)) increases bp(GOBP:"neuron apoptotic process")
pmid:20847424	act(p(HGNC:GSK3B)) positiveCorrelation bp(GOBP:"neuron apoptotic process")
pmid:21945540	act(p(HGNC:GSK3B)) decreases act(p(INTERPRO:"cAMP response element binding (CREB) protein"))
pmid:16914869	p(HGNC:GSK3B) decreases bp(GOBP:memory)
pmid:22122372	act(p(HGNC:GSK3B)) decreases bp(GOBP:memory)
pmid:16914869	p(HGNC:GSK3B) association bp(GOBP:"neuron death")
pmid:17389597	act(p(HGNC:GSK3B)) increases bp(GOBP:"neuron death")
pmid:16914869	p(HGNC:GSK3B) increases complex(GOCC:"neurofibrillary tangle")
pmid:16914869	p(HGNC:GSK3B) association bp(ADO:"loss_of_synapses")
pmid:8764598	act(p(HGNC:GSK3B)) increases p(HGNC:APP, pmod(Ph))
pmid:15686969	act(p(HGNC:GSK3B)) association complex(p(HGNC:APBB1), p(HGNC:MAPT))
pmid:20847424	act(p(HGNC:GSK3B), ma(kin)) increases bp(GOBP:"apoptotic process")
pmid:17360687	act(p(HGNC:GSK3B)) association bp(GOBP:"apoptotic process")
pmid:26420483	p(HGNC:GSK3B) association a(CHEBI:"(R)-ethosuximide")
pmid:22496686	act(p(HGNC:GSK3B)) increases p(HGNC:CTNNB1, pmod(Ph))
pmid:22496686	act(p(HGNC:GSK3B)) increases p(HGNC:CTNNB1, pmod(Ph))
pmid:10341227	act(p(HGNC:GSK3B)) increases p(HGNC:CTNNB1, pmod(Ph))
pmid:17360687	act(p(HGNC:GSK3B)) increases p(HGNC:CTNNB1, pmod(Ph))
pmid:21352912	act(p(HGNC:GSK3B)) increases p(HGNC:CTNNB1, pmod(Ph))
pmid:11527574	act(p(HGNC:GSK3B)) increases p(HGNC:CTNNB1, pmod(Ph))
pmid:19458225	p(HGNC:GSK3B) increases p(HGNC:CTNNB1, pmod(Ph))
pmid:11212302	act(p(HGNC:GSK3B)) increases p(HGNC:CTNNB1, pmod(Ph))
pmid:11504726	p(HGNC:GSK3B) increases p(HGNC:CTNNB1, pmod(Ph))
pmid:22496686	act(p(HGNC:GSK3B)) increases p(HGNC:CTNNB1, pmod(Ph))
pmid:22122372	act(p(HGNC:GSK3B)) decreases bp(GOBP:"generation of neurons")
pmid:22613765	act(p(HGNC:GSK3B)) increases complex(p(HGNC:APC), p(HGNC:CSNK1A1), p(HGNC:CTNNB1), p(HGNC:GSK3B), p(SFAM:"AXIN Family"))
pmid:10967351	p(HGNC:GSK3B) association path(MESHD:"Alzheimer Disease")
pmid:15314261	p(HGNC:GSK3B) association path(MESHD:"Alzheimer Disease")
pmid:17389597	act(p(HGNC:GSK3B)) association path(MESHD:"Alzheimer Disease")
pmid:20056834	act(p(HGNC:GSK3B)) increases bp(GOBP:"inflammatory response")
pmid:20056834	act(p(HGNC:GSK3B)) increases bp(GOBP:"inflammatory response")
pmid:20056834	act(p(HGNC:GSK3B)) increases p(HGNC:CXCL10)
pmid:20056834	act(p(HGNC:GSK3B)) increases p(HGNC:CCL2)
pmid:20056834	act(p(HGNC:GSK3B)) increases p(HGNC:CXCL8)
pmid:20056834	act(p(HGNC:GSK3B)) increases p(HGNC:CCL5)
pmid:20056834	act(p(HGNC:GSK3B)) increases p(HGNC:CXCL1)
pmid:20056834	act(p(HGNC:GSK3B)) decreases bp(GOBP:"maintenance of permeability of blood-brain barrier")
pmid:19885299	act(p(HGNC:GSK3B)) regulates bp(MESHPP:"Energy Metabolism")
pmid:19519303	p(HGNC:GSK3B) increases complex(p(HGNC:IGF1), p(HGNC:INSR))
pmid:19519303	act(p(HGNC:GSK3B)) association bp(GOBP:"TOR signaling")
pmid:19519303	act(p(HGNC:GSK3B)) negativeCorrelation p(HGNC:PIK3CA)
pmid:19519303	act(p(HGNC:GSK3B)) isA complex(p(HGNC:GSK3B), p(HGNC:PPP2CA))
pmid:23362255	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph, Ser))
pmid:23362255	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph, Thr))
pmid:21985244	act(p(HGNC:GSK3B)) positiveCorrelation p(HGNC:SNCA)
pmid:21598254	act(p(HGNC:GSK3B)) negativeCorrelation bp(GOBP:"insulin receptor signaling pathway via phosphatidylinositol 3-kinase")
pmid:21598254	act(p(HGNC:GSK3B)) increases bp(GOBP:"regulation of tau-protein kinase activity")
pmid:22718609	act(p(HGNC:GSK3B)) increases a(HBP:"amyloid-beta aggregates")
pmid:24262633	act(p(HGNC:GSK3B)) association path(MESHD:Inflammation)
pmid:24262633	act(p(HGNC:GSK3B)) association act(p(HGNC:NFE2L2))
pmid:24262633	p(HGNC:GSK3B) association p(HGNC:NFE2L2)
pmid:17160145	p(HGNC:GSK3B) association complex(p(HGNC:CDK5), p(HGNC:CDK5R1))
pmid:16316932	act(p(HGNC:GSK3B)) increases p(HGNC:BAX, pmod(Ph))
pmid:15525785	p(HGNC:GSK3B) increases p(HGNC:BAX, pmod(Ph))
pmid:15525785	p(HGNC:GSK3B) regulates act(p(HGNC:BAX))
pmid:17389597	act(p(HGNC:GSK3B)) increases p(HGNC:PSEN1, pmod(Ph, Ser, 353))
pmid:11104755	act(p(HGNC:GSK3B)) increases p(HGNC:PSEN1, pmod(Ph, Ser, 353))
pmid:17360711	act(p(HGNC:GSK3B)) increases p(HGNC:PSEN1, pmod(Ph, Ser, 353))
pmid:11104755	act(p(HGNC:GSK3B)) increases p(HGNC:PSEN1, pmod(Ph, Ser, 353))
pmid:17389597	act(p(HGNC:GSK3B)) increases p(HGNC:PSEN1, pmod(Ph, Ser, 357))
pmid:11104755	act(p(HGNC:GSK3B)) increases p(HGNC:PSEN1, pmod(Ph, Ser, 357))
pmid:17360711	act(p(HGNC:GSK3B)) increases p(HGNC:PSEN1, pmod(Ph, Ser, 357))
pmid:11104755	act(p(HGNC:GSK3B)) increases p(HGNC:PSEN1, pmod(Ph, Ser, 357))
pmid:17389597	act(p(HGNC:GSK3B)) decreases bp(GOBP:"regulation of synaptic plasticity")
pmid:17389597	act(p(HGNC:GSK3B)) regulates complex(p(HGNC:CDH2), p(HGNC:CTNNB1), p(HGNC:PSEN1))
pmid:16866215	act(p(HGNC:GSK3B)) increases p(HGNC:DPYSL2, pmod(Ph))
pmid:17683481	act(p(HGNC:GSK3B)) increases p(HGNC:DPYSL2, pmod(Ph))
pmid:17902168	p(HGNC:GSK3B) increases p(HGNC:DPYSL2, pmod(Ph))
pmid:15676027	act(p(HGNC:GSK3B)) positiveCorrelation p(HGNC:DPYSL2, pmod(Ph))
pmid:15676027	act(p(HGNC:GSK3B)) increases p(HGNC:DPYSL2, pmod(Ph))
pmid:9565682	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph, Ser, 199))
pmid:9565682	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph, Thr, 231))
pmid:9565682	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:9565682	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph, Ser, 413))
pmid:10998059	act(p(HGNC:GSK3B)) negativeCorrelation a(CHEBI:alsterpaullone)
pmid:21352912	act(p(HGNC:GSK3B)) association p(SFAM:"AXIN Family")
pmid:21352912	act(p(HGNC:GSK3B)) association p(HGNC:APC)
pmid:11527574	act(p(HGNC:GSK3B)) increases complex(SCOMP:"AP-1 Complex")
pmid:11527574	act(p(HGNC:GSK3B)) increases p(HGNC:CREB3L4, pmod(Ph))
pmid:11527574	act(p(HGNC:GSK3B)) increases p(HGNC:HSF1, pmod(Ph))
pmid:11527574	act(p(HGNC:GSK3B)) increases p(HGNC:MYC, pmod(Ph))
pmid:11527574	act(p(HGNC:GSK3B)) increases p(HGNC:NFATC2, pmod(Ph))
pmid:11527574	act(p(HGNC:GSK3B)) regulates complex(SCOMP:"Nfkb Complex")
pmid:11527574	p(HGNC:GSK3B) decreases p(HGNC:CTNNB1)
pmid:20847424	act(p(HGNC:GSK3B)) negativeCorrelation p(HGNC:CTNNB1)
pmid:16257959	act(p(HGNC:GSK3B)) increases p(HGNC:MARK2, pmod(Ph))
pmid:16257959	act(p(HGNC:GSK3B)) increases p(HGNC:MARK2, pmod(Ph))
pmid:16257959	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph, Ser, 262))
pmid:8769876	act(p(HGNC:GSK3B)) increases p(HGNC:MAPT, pmod(Ph, Ser, 262))
pmid:16814287	act(p(HGNC:GSK3B)) increases p(HGNC:PSEN1, pmod(Ph))
pmid:17389597	act(p(HGNC:GSK3B)) increases p(HGNC:PSEN1, pmod(Ph))
pmid:17389597	act(p(HGNC:GSK3B)) decreases complex(p(HGNC:CDH2), p(HGNC:PSEN1))
pmid:17389597	act(p(HGNC:GSK3B)) decreases tloc(p(HGNC:PSEN1), fromLoc(GOCC:intracellular), toLoc(GOCC:"cell surface"))
PubMed Central:PMC21391	p(HGNC:GSK3B) association p(HGNC:PSEN1)
pmid:21945540	act(p(HGNC:GSK3B)) decreases r(HGNC:BDNF)
pmid:17213958	p(HGNC:GSS) directlyDecreases bp(GOBP:"neuron apoptotic process")
pmid:17213958	p(HGNC:GSS) directlyDecreases act(p(HGNC:ACHE), ma(pep))
pmid:19885299	act(p(HGNC:IGF1)) regulates g(HGNC:CHAT)
pmid:19885299	p(HGNC:IGF1) positiveCorrelation bp(GOBP:"acetylcholine secretion")
pmid:16444902	p(HGNC:IGF1) increases p(HGNC:APP, frag("672_713"))
pmid:23557940	act(p(HGNC:IGF1)) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:19885299	p(HGNC:IGF1) directlyIncreases act(p(HGNC:IGF1R))
pmid:19885299	p(HGNC:IGF1) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19531281	p(HGNC:IGF1) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19885299	p(HGNC:IGF1) negativeCorrelation path(MESHD:Dementia)
pmid:19885299	p(HGNC:IGF1) negativeCorrelation act(a(MESH:D001253))
pmid:19885299	p(HGNC:IGF1) negativeCorrelation act(a(MESH:D017628))
pmid:19885299	act(p(HGNC:IGF1)) association r(HGNC:MAPT)
pmid:19885299	p(HGNC:IGF1) positiveCorrelation a(GOCC:cytoskeleton)
pmid:19885299	p(HGNC:IGF1) negativeCorrelation bp(HBP:"neurite retraction")
pmid:19885299	p(HGNC:IGF1) negativeCorrelation bp(GOBP:"long term synaptic depression")
pmid:19885299	p(HGNC:IGF1) positiveCorrelation bp(MESHPP:"Neuronal Plasticity")
pmid:19519303	act(p(HGNC:IGF1)) association bp(GOBP:"glucose import")
pmid:19519303	act(p(HGNC:IGF1)) association bp(GOBP:"cell proliferation")
pmid:19519303	act(p(HGNC:IGF1)) decreases bp(GOBP:"glucose metabolic process")
pmid:20847424	p(HGNC:IGF1) increases bp(GOBP:"glucose metabolic process")
pmid:19519303	act(p(HGNC:IGF1)) positiveCorrelation bp(GOBP:"energy homeostasis")
pmid:19519303	act(p(HGNC:IGF1)) positiveCorrelation bp(MESHPP:"Cell Survival")
pmid:19519303	act(p(HGNC:IGF1)) association bp(GOBP:"learning or memory")
pmid:19519303	act(p(HGNC:IGF1)) association bp(MESHPP:Longevity)
pmid:19519303	p(HGNC:IGF1) regulates bp(GOBP:"MAPK cascade")
pmid:19519303	act(p(HGNC:IGF1)) increases complex(p(HGNC:GRB2), p(SFAM:"IRS Family"))
pmid:19519303	act(p(HGNC:IGF1)) increases complex(p(HGNC:GAB1), p(HGNC:GRB2))
pmid:19519303	act(p(HGNC:IGF1)) increases act(g(HGNC:NGFR))
pmid:19519303	act(p(HGNC:IGF1)) association bp(GOBP:"maintenance of permeability of blood-brain barrier")
pmid:19519303	p(HGNC:IGF1) regulates p(HGNC:MAPT, pmod(Ph))
pmid:19519303	p(HGNC:IGF1) increases act(r(HGNC:NGFR), ma(tscript))
pmid:22524398	p(HGNC:IGF1) increases bp(MESH:D000066829)
pmid:22524398	p(HGNC:IGF1) increases bp(GOBP:"brain development")
pmid:22524398	p(HGNC:IGF1) increases p(HGNC:ADAM10)
pmid:22005929	p(HGNC:IGF1) negativeCorrelation act(p(HGNC:TNF))
pmid:23557940	act(p(HGNC:IGF1)) negativeCorrelation bp(GOBP:"neuron death")
pmid:23557940	act(p(HGNC:IGF1)) negativeCorrelation complex(GOCC:"neurofibrillary tangle")
pmid:23557940	p(HGNC:IGF1) increases act(p(HGNC:ALB))
pmid:23557940	p(HGNC:IGF1) increases act(p(HGNC:TTR))
pmid:23557940	act(p(HGNC:IGF1)) increases bp(GO:"GO:0097242")
pmid:20351102	p(HGNC:IGF1) directlyIncreases complex(p(HGNC:IGF1), p(HGNC:LRP2))
pmid:20351102	p(HGNC:IGF1) association p(HGNC:LRP2)
pmid:16444902	p(HGNC:IGF1) association bp(GOBP:"glucose homeostasis")
pmid:16444902	p(HGNC:IGF1) association bp(GOBP:"glucose catabolic process")
pmid:20847424	p(HGNC:IGF1) increases act(complex(p(HGNC:GSK3A), p(HGNC:PDPK1), p(HGNC:PIK3R5)))
pmid:20847424	p(HGNC:IGF1) increases act(complex(p(HGNC:GSK3B), p(HGNC:PDPK1), p(HGNC:PIK3R5)))
pmid:20847424	p(HGNC:IGF1) increases bp(GOBP:"energy reserve metabolic process")
pmid:20847424	p(HGNC:IGF1) increases bp(GOBP:"negative regulation of neuron apoptotic process")
pmid:20847424	act(p(HGNC:IGF1)) increases act(p(SFAM:"PIK3C Class IA Family"))
pmid:20847424	act(p(HGNC:IGF1)) increases p(HGNC:IRS1, pmod(Ph, Thr))
pmid:20847424	act(p(HGNC:IGF1)) increases p(HGNC:IRS2, pmod(Ph, Thr))
pmid:23759148	p(HGNC:IL1B) association p(HGNC:BCHE)
pmid:15232608	p(HGNC:IL1B) increases bp(GOBP:"neuron apoptotic process")
pmid:10850859	p(HGNC:IL1B) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:18021299	p(HGNC:IL1B) association path(MESHD:"Alzheimer Disease")
pmid:10850859	p(HGNC:IL1B) increases a(CHEBI:"amyloid-beta")
pmid:18021299	p(HGNC:IL1B) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:18021299	p(HGNC:IL1B) increases act(p(HGNC:ADAM10), ma(pep))
pmid:18021299	p(HGNC:IL1B) increases a(HBP:"sAPP-alpha")
pmid:18021299	p(HGNC:IL1B) decreases a(HBP:"sAPP-beta")
pmid:18021299	p(HGNC:IL1B) decreases p(HGNC:APP, frag("672_711"))
pmid:18021299	p(HGNC:IL1B) decreases p(HGNC:APP, frag("672_713"))
pmid:10037734	p(HGNC:IL1B) increases p(HGNC:APP)
pmid:18715507	p(HGNC:IL1B) association bp(GOBP:"microglial cell activation involved in immune response")
pmid:22493750	p(HGNC:IL1B) association bp(GOBP:"inflammatory response")
pmid:21143158	p(HGNC:IL1B) increases bp(GOBP:"inflammatory response")
pmid:20127816	tloc(p(HGNC:IL1B), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space")) increases bp(GOBP:"inflammatory response")
pmid:10037734	p(HGNC:IL1B) increases bp(HBP:neuroinflammation)
pmid:25681350	p(HGNC:IL1B) positiveCorrelation p(HGNC:CHI3L1)
pmid:25681350	p(HGNC:IL1B) positiveCorrelation p(HGNC:CHI3L1)
pmid:18021299	p(HGNC:IL1B) increases act(p(HGNC:ADAM17), ma(pep))
pmid:19885299	act(p(HGNC:INS)) increases r(HGNC:CHAT)
pmid:19885299	p(HGNC:INS) positiveCorrelation bp(GOBP:"acetylcholine secretion")
pmid:11956956	act(p(HGNC:INS)) regulates bp(GOBP:"acetylcholine metabolic process")
pmid:16444902	p(HGNC:INS) increases p(HGNC:APP, frag("672_713"))
pmid:19237574	p(HGNC:INS) regulates p(HGNC:APP, frag("672_713"))
pmid:16399206	p(HGNC:INS) increases tloc(p(HGNC:APP, frag("672_713")), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:11956956	act(p(HGNC:INS)) association a(CHEBI:"amyloid-beta")
pmid:11956956	p(HGNC:INS) negativeCorrelation a(CHEBI:"amyloid-beta")
pmid:19885299	p(HGNC:INS) directlyIncreases act(p(HGNC:INSR))
pmid:19188609	act(p(HGNC:INS)) positiveCorrelation tloc(p(HGNC:INSR), fromLoc(GOCC:intracellular), toLoc(GOCC:"cell surface"))
pmid:20847424	p(HGNC:INS) increases act(p(HGNC:INSR))
pmid:19519303	p(HGNC:INS) increases complex(p(HGNC:GSK3B), p(HGNC:PPP2CA))
pmid:19885299	p(HGNC:INS) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19885299	p(HGNC:INS) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19383491	p(HGNC:INS) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19383491	p(HGNC:INS) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:12185156	act(p(HGNC:INS)) association path(MESHD:"Alzheimer Disease")
pmid:19885299	p(HGNC:INS) increases r(HGNC:MAPT)
pmid:19885299	act(p(HGNC:INS)) regulates r(HGNC:MAPT)
pmid:19885299	p(HGNC:INS) increases p(HGNC:MAPT, pmod(Ph))
pmid:19519303	p(HGNC:INS) increases p(HGNC:MAPT, pmod(Ph))
pmid:19519303	p(HGNC:INS) regulates p(HGNC:MAPT, pmod(Ph))
pmid:16399206	p(HGNC:INS) increases p(HGNC:MAPT, pmod(Ph))
pmid:21598254	p(HGNC:INS) negativeCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:11956956	act(p(HGNC:INS)) association p(HGNC:MAPT, pmod(Ph))
pmid:19885299	p(HGNC:INS) negativeCorrelation path(MESHD:Dementia)
pmid:19885299	p(HGNC:INS) negativeCorrelation act(a(MESH:D001253))
pmid:19885299	p(HGNC:INS) negativeCorrelation act(a(MESH:D017628))
pmid:19885299	p(HGNC:INS) positiveCorrelation a(GOCC:cytoskeleton)
pmid:19885299	p(HGNC:INS) negativeCorrelation bp(HBP:"neurite retraction")
pmid:19885299	p(HGNC:INS) negativeCorrelation bp(GOBP:"long term synaptic depression")
pmid:19885299	p(HGNC:INS) positiveCorrelation bp(MESHPP:"Neuronal Plasticity")
pmid:19885299	p(HGNC:INS) causesNoChange bp(GOBP:"glucose transport")
pmid:19885299	p(HGNC:INS) positiveCorrelation bp(GOBP:"learning or memory")
pmid:19519303	act(p(HGNC:INS)) association bp(GOBP:"learning or memory")
pmid:19885299	p(HGNC:INS) regulates bp(GOBP:cognition)
pmid:19885299	p(HGNC:INS) increases bp(GOBP:cognition)
pmid:19519303	p(HGNC:INS) increases bp(GOBP:cognition)
pmid:19885299	p(HGNC:INS) increases bp(GOBP:memory)
pmid:19519303	p(HGNC:INS) increases bp(GOBP:memory)
pmid:19519303	act(p(HGNC:INS)) association bp(GOBP:"glucose import")
pmid:19519303	act(p(HGNC:INS)) association bp(GOBP:"cell proliferation")
pmid:19519303	act(p(HGNC:INS)) decreases bp(GOBP:"glucose metabolic process")
pmid:17316694	act(p(HGNC:INS)) increases bp(GOBP:"glucose metabolic process")
pmid:19519303	act(p(HGNC:INS)) positiveCorrelation bp(GOBP:"energy homeostasis")
pmid:19519303	act(p(HGNC:INS)) positiveCorrelation bp(MESHPP:"Cell Survival")
pmid:19519303	act(p(HGNC:INS)) association bp(MESHPP:Longevity)
pmid:19519303	p(HGNC:INS) regulates bp(GOBP:"MAPK cascade")
pmid:19519303	act(p(HGNC:INS)) increases complex(p(HGNC:GRB2), p(SFAM:"IRS Family"))
pmid:19519303	act(p(HGNC:INS)) increases complex(p(HGNC:GAB1), p(HGNC:GRB2))
pmid:19519303	act(p(HGNC:INS)) association bp(GOBP:"maintenance of permeability of blood-brain barrier")
pmid:19519303	p(HGNC:INS) association bp(GOBP:"maintenance of permeability of blood-brain barrier")
pmid:19519303	p(HGNC:INS) causesNoChange a(CHEBI:glucose)
pmid:16399206	p(HGNC:INS) decreases act(p(HGNC:IDE))
pmid:18411275	deg(p(HGNC:INS)) association p(HGNC:IDE)
pmid:18941241	p(HGNC:INS) decreases p(HGNC:IDE)
pmid:16399206	p(HGNC:INS) association bp(GOBP:"amyloid precursor protein catabolic process")
pmid:23627755	p(HGNC:INS) association bp(GOBP:"regulation of amyloid precursor protein catabolic process")
pmid:19383491	p(HGNC:INS) increases tloc(p(HGNC:SLC2A4), fromLoc(MESHCS:"Intracellular Space"), toLoc(MESHCS:"Cell Membrane"))
pmid:19383491	p(HGNC:INS) increases tloc(p(HGNC:SLC2A8), fromLoc(MESHCS:"Intracellular Space"), toLoc(MESHCS:"Cell Membrane"))
pmid:19383491	p(HGNC:INS) increases a(CHEBI:cortisol)
pmid:19383491	p(HGNC:INS) association bp(MESHPP:"Long-Term Potentiation")
pmid:19383491	p(HGNC:INS) increases p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")
pmid:19383491	p(HGNC:INS) decreases p(HGNC:APP)
pmid:19383491	p(HGNC:INS) increases p(HGNC:APP)
pmid:21598254	p(HGNC:INS) positiveCorrelation act(p(HGNC:OGT))
pmid:11956956	act(p(HGNC:INS)) regulates bp(GOBP:"glucose homeostasis")
pmid:11956956	act(p(HGNC:INS)) regulates a(CHEBI:cholesterol)
pmid:11956956	act(p(HGNC:INS)) association bp(GOBP:"regulation of ATPase activity")
pmid:19188609	act(p(HGNC:INS)) decreases act(a(HBP:"amyloid-beta derived diffusible ligands"))
pmid:18941241	p(HGNC:INS) decreases act(p(HGNC:IL4))
pmid:17213958	p(HGNC:NGF) directlyDecreases act(p(HGNC:ACHE), ma(pep))
pmid:17213958	p(HGNC:NGF) directlyDecreases bp(GOBP:"neuron apoptotic process")
pmid:17213958	p(HGNC:NGF) directlyDecreases tloc(p(HGNC:CYCS), fromLoc(MESH:D008928), toLoc(MESHCS:Cytosol))
pmid:22550546	p(HGNC:NGF) increases p(HGNC:APP)
pmid:21849536	p(HGNC:NGF) increases p(HGNC:APP, pmod(Ph, Tyr, 682))
pmid:21849536	p(HGNC:NGF) increases complex(p(HGNC:APP), p(HGNC:NTRK1))
pmid:15474976	p(HGNC:PPARG) positiveCorrelation bp(HBP:neuroinflammation)
pmid:23197723	p(HGNC:PPARG) increases bp(GOBP:"microglial cell activation")
pmid:11755002	act(p(HGNC:PPARG)) decreases bp(GOBP:"microglial cell activation involved in immune response")
pmid:11755002	act(p(HGNC:PPARG)) increases bp(GOBP:"production of molecular mediator involved in inflammatory response")
pmid:11755002	p(HGNC:PPARG) association bp(GOBP:"chronic inflammatory response")
pmid:21311715	p(HGNC:PPARG) directlyIncreases g(HGNC:LRP2)
pmid:16472958	p(HGNC:PPARG) regulates p(HGNC:NOS2)
pmid:19660836	p(HGNC:PPARG) decreases p(HGNC:APP, frag("672_713"))
pmid:16828233	p(HGNC:PPARG) decreases p(HGNC:APP, frag("672_713"))
pmid:19885299	p(HGNC:PPARG) decreases a(CHEBI:"amyloid-beta")
pmid:19885299	act(p(HGNC:PPARG)) decreases tloc(a(CHEBI:"amyloid-beta"), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:16828233	p(HGNC:PPARG) decreases a(CHEBI:"amyloid-beta")
pmid:19885299	p(HGNC:PPARG) increases deg(p(HGNC:APP, pmod(Ub)))
pmid:15946122	p(HGNC:PPARG) increases p(HGNC:APP, pmod(Ub))
pmid:19885299	act(p(HGNC:PPARG)) decreases bp(GOBP:"hydrogen peroxide-mediated programmed cell death")
pmid:15946122	p(HGNC:PPARG) directlyDecreases bp(GOBP:"necrotic cell death")
pmid:21800078	p(HGNC:PPARG) directlyDecreases p(HGNC:BACE1)
pmid:19887909	p(HGNC:PRNP) decreases act(p(HGNC:BACE1), ma(pep))
pmid:18479216	p(HGNC:PRNP) decreases act(p(HGNC:BACE1), ma(pep))
pmid:17573534	p(HGNC:PRNP) regulates act(p(HGNC:BACE1), ma(pep))
pmid:23577068	p(HGNC:PRNP) decreases act(p(HGNC:BACE1), ma(pep))
pmid:17573534	p(HGNC:PRNP) increases path(MESHD:"Creutzfeldt-Jakob Syndrome")
pmid:19887909	p(HGNC:PRNP) association path(MESHD:"Alzheimer Disease")
pmid:23577068	p(HGNC:PRNP) association path(MESHD:"Alzheimer Disease")
pmid:18479216	p(HGNC:PRNP) decreases a(CHEBI:"amyloid-beta")
pmid:19822779	p(HGNC:PRNP) increases a(CHEBI:"amyloid-beta")
pmid:17573534	p(HGNC:PRNP) decreases p(HGNC:APP, frag("672_713"))
pmid:17573534	p(HGNC:PRNP) regulates p(HGNC:APP, frag("672_713"))
pmid:23577068	p(HGNC:PRNP) decreases p(HGNC:APP, frag("672_713"))
pmid:23759148	p(HGNC:S100B) association p(HGNC:BCHE)
pmid:18494933	p(HGNC:S100B) increases p(HGNC:GSK3B, pmod(Ph))
pmid:18494933	p(HGNC:S100B) increases p(HGNC:DKK1)
pmid:21209080	p(HGNC:S100B) increases bp(GOBP:"telencephalon microglial cell migration")
pmid:21209080	p(HGNC:S100B) increases act(p(HGNC:MOK))
pmid:21143158	p(HGNC:S100B) increases bp(GOBP:"inflammatory response")
pmid:18494933	p(HGNC:S100B) increases complex(GOCC:"neurofibrillary tangle")
pmid:18494933	p(HGNC:S100B) increases p(HGNC:MAPT, pmod(Ph))
pmid:23759148	p(HGNC:TNF) association p(HGNC:BCHE)
pmid:15232608	p(HGNC:TNF) increases bp(GOBP:"neuron apoptotic process")
pmid:22277195	p(HGNC:TNF) increases bp(GOBP:"neuron apoptotic process")
pmid:24966471	p(HGNC:TNF) increases bp(GOBP:"cell death")
pmid:24966471	p(HGNC:TNF) increases p(MESHC:"NMDA receptor A1")
pmid:24966471	p(HGNC:TNF) increases p(MESHC:"NR1 NMDA receptor")
pmid:24966471	p(HGNC:TNF) increases p(MESHC:"NR2A NMDA receptor")
pmid:24966471	p(HGNC:TNF) increases p(MESHC:"NR2B NMDA receptor")
pmid:24966471	p(HGNC:TNF) increases p(MESHC:"NR2C NMDA receptor")
pmid:24966471	p(HGNC:TNF) increases p(MESHC:"NR2D NMDA receptor")
pmid:24966471	p(HGNC:TNF) increases p(MESHC:"NR3A NMDA receptor")
pmid:24966471	p(HGNC:TNF) increases p(MESHC:"NR3B NMDA receptor")
pmid:24966471	p(HGNC:TNF) decreases complex(GOCC:"GABA receptor complex")
pmid:24966471	p(HGNC:TNF) increases p(MESHC:"metabotropic quisqualate receptor")
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRA1)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRA2)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRA3)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRA4)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRA5)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRA6)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRB1)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRB2)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRB3)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRG1)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRG2)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRG3)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRD)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRE)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRP)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABRQ)
pmid:24966471	p(HGNC:TNF) decreases p(HGNC:GABBR1)
pmid:22277195	p(HGNC:TNF) increases bp(GOBP:"production of molecular mediator involved in inflammatory response")
pmid:22566778	p(HGNC:TNF) increases bp(GOBP:"production of molecular mediator involved in inflammatory response")
pmid:22277195	p(HGNC:TNF) increases path(MESHD:"Neurogenic Inflammation")
pmid:22441986	p(HGNC:TNF) increases bp(GOBP:"immune response")
pmid:22441986	p(HGNC:TNF) association p(SFAM:"TNFRSF Family")
pmid:20555131	p(HGNC:TNF) association bp(GOBP:"inflammatory response")
pmid:18715507	p(HGNC:TNF) association bp(GOBP:"microglial cell activation involved in immune response")
pmid:18554520	p(HGNC:TNF) association path(MESHD:Inflammation)
pmid:22566778	p(HGNC:TNF) positiveCorrelation bp(HBP:neuroinflammation)
pmid:19885299	act(p(HGNC:TNF)) negativeCorrelation bp(GOBP:"insulin receptor signaling pathway")
pmid:19885299	act(p(HGNC:TNF)) negativeCorrelation bp(GOBP:"insulin-like growth factor receptor signaling pathway")
pmid:22524398	p(HGNC:TNF) decreases p(HGNC:IGF1)
pmid:22005929	act(p(HGNC:TNF)) negativeCorrelation p(HGNC:IGF1)
pmid:23557940	p(HGNC:TNF) decreases act(p(HGNC:IGF1))
pmid:23557940	p(HGNC:TNF) decreases bp(GO:"GO:0097242")
pmid:18554520	p(HGNC:TNF) association p(HGNC:MPO)
pmid:19013138	p(MGI:Chat) association bp(GOBP:"insulin receptor signaling pathway")
pmid:20938992	p(MGI:Chrnb1) negativeCorrelation a(CHEBI:methionine)
pmid:20938992	p(MGI:Chrnb1) negativeCorrelation a(CHEBI:choline)
pmid:20938992	p(MGI:Chrnb1) negativeCorrelation a(CHEBI:"folic acid")
pmid:21158163	p(RGD:Ins2) increases bp(GOBP:learning)
pmid:21158163	p(RGD:Ins2) increases bp(GOBP:memory)
pmid:21158163	p(RGD:Ins2) increases p(RGD:Chrna2)
pmid:21158163	p(RGD:Ins2) increases p(RGD:Chrna3)
pmid:21158163	p(RGD:Ins2) increases p(RGD:Chrna4)
pmid:21158163	p(RGD:Ins2) increases p(RGD:Chrna5)
pmid:21158163	p(RGD:Ins2) increases p(RGD:Chrna6)
pmid:21158163	p(RGD:Ins2) increases p(RGD:Chrna7)
pmid:21158163	p(RGD:Ins2) increases p(RGD:Chrna9)
pmid:21158163	p(RGD:Ins2) increases p(RGD:Chrna10)
pmid:21158163	p(RGD:Ins2) increases p(RGD:Chrnb2)
pmid:21158163	p(RGD:Ins2) increases p(RGD:Chrnb3)
pmid:21158163	p(RGD:Ins2) increases p(RGD:Chrnb4)
pmid:17213958	deg(p(SFAM:"AKT Family")) directlyIncreases act(p(HGNC:ACHE), ma(pep))
pmid:19885299	act(p(SFAM:"AKT Family")) increases p(HGNC:GSK3B, pmod(Ph, Ser, 9))
pmid:20847424	act(p(SFAM:"AKT Family")) increases p(HGNC:GSK3B, pmod(Ph, Ser, 9))
pmid:19885299	act(p(SFAM:"AKT Family")) increases p(HGNC:GSK3A, pmod(Ph, Ser, 21))
pmid:20847424	act(p(SFAM:"AKT Family")) increases p(HGNC:GSK3A, pmod(Ph, Ser, 21))
pmid:19885299	act(p(SFAM:"AKT Family")) decreases act(p(HGNC:BAD))
pmid:16316932	act(p(SFAM:"AKT Family")) decreases p(HGNC:BAD)
pmid:19885299	act(p(SFAM:"AKT Family")) decreases bp(GOBP:"apoptotic process")
pmid:16316932	act(p(SFAM:"AKT Family")) decreases act(p(HGNC:GSK3B))
pmid:20847424	act(p(SFAM:"AKT Family")) decreases act(p(HGNC:GSK3B))
pmid:16316932	act(p(SFAM:"AKT Family")) decreases p(HGNC:BAX)
pmid:20847424	act(p(SFAM:"AKT Family")) decreases act(p(HGNC:GSK3A))
pmid:17213958	act(p(SFAM:"CASP Family"), ma(kin)) directlyIncreases act(p(HGNC:ACHE), ma(pep))
pmid:12675140	path(MESHD:"Alzheimer Disease") negativeCorrelation bp(GOBP:"regulation of synaptic transmission, cholinergic")
pmid:21821968	path(MESHD:"Alzheimer Disease") decreases bp(GOBP:"regulation of synaptic transmission, cholinergic")
pmid:22445674	path(MESHD:"Alzheimer Disease") negativeCorrelation act(p(HGNC:BCHE))
pmid:17096857	path(MESHD:"Alzheimer Disease") association p(HGNC:BCHE)
pmid:22445674	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:ACHE)
pmid:17096857	path(MESHD:"Alzheimer Disease") association p(HGNC:ACHE)
pmid:12214130	path(MESHD:"Alzheimer Disease") association p(HGNC:CHRNA4, var("p.Ser413Leu"))
pmid:12214130	path(MESHD:"Alzheimer Disease") association p(HGNC:CHRNB2, var("p.Gln397Pro"))
pmid:19885299	path(MESHD:"Alzheimer Disease") negativeCorrelation g(HGNC:CHAT)
pmid:18070217	path(MESHD:"Alzheimer Disease") decreases bp(GOBP:"synaptic transmission, cholinergic")
pmid:19272425	path(MESHD:"Alzheimer Disease") decreases bp(GOBP:"synaptic transmission, cholinergic")
pmid:8019853	path(MESHD:"Alzheimer Disease") decreases bp(GOBP:"glucose metabolic process")
pmid:8019853	path(MESHD:"Alzheimer Disease") decreases bp(GOBP:"blood circulation")
pmid:21821968	path(MESHD:"Alzheimer Disease") increases bp(GOBP:"negative regulation of synaptic transmission, glutamatergic")
pmid:22434822	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:CLSTN1)
pmid:16696577	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:APP, frag("672_713"))
pmid:15177383	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:APP, frag("672_713"))
pmid:18584921	path(MESHD:"Alzheimer Disease") association p(HGNC:APP, frag("672_713"))
pmid:26996954	path(MESHD:"Alzheimer Disease") increases p(HGNC:APP, frag("672_713"))
pmid:14970312	path(MESHD:"Alzheimer Disease") increases p(HGNC:APP, frag("672_713"))
pmid:23577068	path(MESHD:"Alzheimer Disease") association p(HGNC:APP, frag("672_713"))
pmid:16696577	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:APP, frag("672_711"))
pmid:23296004	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:ARRB2)
pmid:22702962	path(MESHD:"Alzheimer Disease") positiveCorrelation g(HGNC:APP, var("c.275341G>C"))
pmid:22702962	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:APP, var("p.Val717Leu"))
pmid:22710270	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:PSEN1, var("p.Glu280Ala"))
pmid:21769591	path(MESHD:"Alzheimer Disease") association p(HGNC:APOE)
pmid:22496686	path(MESHD:"Alzheimer Disease") association p(HGNC:APOE)
pmid:11070505	path(MESHD:"Alzheimer Disease") association p(HGNC:APOE)
pmid:12015813	path(MESHD:"Alzheimer Disease") association p(HGNC:APOE)
pmid:14501024	path(MESHD:"Alzheimer Disease") association p(HGNC:APOE)
pmid:7695621	path(MESHD:"Alzheimer Disease") association p(HGNC:APOE)
pmid:16687508	path(MESHD:"Alzheimer Disease") association bp(GOBP:"intrinsic apoptotic signaling pathway in response to oxidative stress")
pmid:20597865	path(MESHD:"Alzheimer Disease") association g(HGNC:CTSD)
pmid:22447723	path(MESHD:"Alzheimer Disease") decreases bp(GOBP:"zinc ion homeostasis")
pmid:22399757	path(MESHD:"Alzheimer Disease") association bp(GOBP:"regulation of ubiquitin-specific protease activity")
pmid:17314098	path(MESHD:"Alzheimer Disease") association p(HGNC:PSEN1)
pmid:22382662	path(MESHD:"Alzheimer Disease") association p(HGNC:PSEN1)
pmid:17314098	path(MESHD:"Alzheimer Disease") association p(HGNC:PSEN2)
pmid:14585504	path(MESHD:"Alzheimer Disease") association p(HGNC:PSEN2)
pmid:22382662	path(MESHD:"Alzheimer Disease") association p(HGNC:PSEN2)
pmid:22382662	path(MESHD:"Alzheimer Disease") positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:16687508	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:15331417	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:17495608	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:17185504	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:16027115	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:17205046	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:17360493	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:19199126	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:19355846	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:19462468	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:19698775	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:20138836	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:20157255	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:12473667	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:14622952	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:16306400	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:17541560	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:8626687	path(MESHD:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
pmid:22382662	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:18584921	path(MESHD:"Alzheimer Disease") association p(HGNC:MAPT, pmod(Ph))
pmid:23362255	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:21666500	path(MESHD:"Alzheimer Disease") association p(HGNC:MAPT, pmod(Ph))
pmid:20157255	path(MESHD:"Alzheimer Disease") association p(HGNC:MAPT, pmod(Ph))
pmid:17954934	path(MESHD:"Alzheimer Disease") association p(HGNC:MAPT, pmod(Ph))
pmid:14673212	path(MESHD:"Alzheimer Disease") association p(HGNC:MAPT, pmod(Ph))
pmid:17120162	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:9565682	path(MESHD:"Alzheimer Disease") association p(HGNC:MAPT, pmod(Ph))
pmid:7533559	path(MESHD:"Alzheimer Disease") association p(HGNC:MAPT, pmod(Ph))
pmid:8730715	path(MESHD:"Alzheimer Disease") association p(HGNC:MAPT, pmod(Ph))
pmid:15658002	path(MESHD:"Alzheimer Disease") association p(HGNC:MAPT, pmod(Ph))
pmid:22355143	path(MESHD:"Alzheimer Disease") association p(HGNC:APBA1)
pmid:15452128	path(MESHD:"Alzheimer Disease") association act(p(HGNC:BACE1), ma(pep))
pmid:15080893	path(MESHD:"Alzheimer Disease") association p(HGNC:BACE1)
pmid:22367557	path(MESHD:"Alzheimer Disease") negativeCorrelation act(p(SFAM:"PRKA Family"), ma(kin))
pmid:22367557	path(MESHD:"Alzheimer Disease") association p(SFAM:"PRKA Family")
pmid:9202294	path(MESHD:"Alzheimer Disease") association g(HGNC:APOE)
pmid:22430674	path(MESHD:"Alzheimer Disease") positiveCorrelation g(HGNC:FRMD4A)
pmid:18308724	path(MESHD:"Alzheimer Disease") association a(CHEBI:cholesterol)
pmid:22829447	path(MESHD:"Alzheimer Disease") positiveCorrelation bp(MESHPP:"Insulin Resistance")
pmid:22536436	path(MESHD:"Alzheimer Disease") association bp(MESHPP:"Insulin Resistance")
pmid:19519303	path(MESHD:"Alzheimer Disease") association bp(MESHPP:"Insulin Resistance")
pmid:23627755	path(MESHD:"Alzheimer Disease") association bp(MESHPP:"Insulin Resistance")
pmid:20704561	path(MESHD:"Alzheimer Disease") association p(HGNC:ABCA2)
pmid:10850859	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:IL1B)
pmid:18021299	path(MESHD:"Alzheimer Disease") association p(HGNC:IL1B)
pmid:20205643	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:CCL2)
pmid:16687508	path(MESHD:"Alzheimer Disease") association path(MESHD:Dementia)
pmid:21321400	path(MESHD:"Alzheimer Disease") association path(MESHD:Dementia)
pmid:16687508	path(MESHD:"Alzheimer Disease") decreases bp(GOBP:"mitochondria-nucleus signaling pathway")
pmid:16687508	path(MESHD:"Alzheimer Disease") association bp(GOBP:"neuron death")
pmid:14970312	path(MESHD:"Alzheimer Disease") increases bp(GOBP:"neuron death")
pmid:21666500	path(MESHD:"Alzheimer Disease") negativeCorrelation bp(GOBP:"neuron death")
pmid:20847424	path(MESHD:"Alzheimer Disease") decreases bp(GOBP:"cAMP-mediated signaling")
pmid:20385830	path(MESHD:"Alzheimer Disease") negativeCorrelation bp(GOBP:"chemical synaptic transmission")
Online Resource:hsa05010	path(MESHD:"Alzheimer Disease") association g(HGNC:APP)
pmid:9202294	path(MESHD:"Alzheimer Disease") association g(HGNC:APP)
Online Resource:REACT_75925.2	path(MESHD:"Alzheimer Disease") association path(MESHD:Amyloidosis)
pmid:18234899	path(MESHD:"Alzheimer Disease") negativeCorrelation m(HGNC:MIR107)
pmid:20489155	path(MESHD:"Alzheimer Disease") association m(HGNC:MIR107)
pmid:23546882	path(MESHD:"Alzheimer Disease") positiveCorrelation m(HGNC:MIR144)
pmid:21062284	path(MESHD:"Alzheimer Disease") decreases m(HGNC:"MIR124-1")
pmid:22733824	path(MESHD:"Alzheimer Disease") negativeCorrelation m(HGNC:"MIR153-1")
pmid:19734902	path(MESHD:"Alzheimer Disease") association g(HGNC:APBA1)
pmid:23713771	path(MESHD:"Alzheimer Disease") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:IAPP))
pmid:22107728	path(MESHD:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs4646953)
pmid:22844264	path(MESHD:"Alzheimer Disease") association complex(a(CHEBI:"copper(2+)"), p(HGNC:APP, frag("672_713")))
pmid:23040664	path(MESHD:"Alzheimer Disease") association path(MESHD:Inflammation)
pmid:20308780	path(MESHD:"Alzheimer Disease") association path(MESHD:Inflammation)
pmid:18554520	path(MESHD:"Alzheimer Disease") association path(MESHD:Inflammation)
pmid:24332564	path(MESHD:"Alzheimer Disease") association composite(a(CHEBI:"amyloid-beta"), p(HGNC:NOS3), p(HGNC:PIN1))
pmid:23181169	path(MESHD:"Alzheimer Disease") association p(HGNC:ABCB1)
pmid:12742739	path(MESHD:"Alzheimer Disease") increases p(HGNC:FASLG)
pmid:11194936	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:PTGS2)
pmid:10560656	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:PTGS1)
pmid:9489740	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:A2M)
pmid:11816788	path(MESHD:"Alzheimer Disease") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE))
pmid:16207708	path(MESHD:"Alzheimer Disease") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE))
pmid:8040342	path(MESHD:"Alzheimer Disease") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE))
pmid:9265639	path(MESHD:"Alzheimer Disease") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE))
pmid:11840304	path(MESHD:"Alzheimer Disease") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE))
pmid:15181252	path(MESHD:"Alzheimer Disease") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE))
pmid:8631862	path(MESHD:"Alzheimer Disease") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE))
pmid:8679539	path(MESHD:"Alzheimer Disease") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE))
pmid:21297948	path(MESHD:"Alzheimer Disease") association complex(p(HGNC:APOE), p(HGNC:APP))
pmid:20052565	path(MESHD:"Alzheimer Disease") association a(CHEBI:"galactosylceramide sulfate")
pmid:19462468	path(MESHD:"Alzheimer Disease") association p(HGNC:APP)
pmid:16797788	path(MESHD:"Alzheimer Disease") association p(HGNC:APP)
pmid:17314098	path(MESHD:"Alzheimer Disease") association p(HGNC:APP)
pmid:15686969	path(MESHD:"Alzheimer Disease") association p(HGNC:APP)
pmid:19887909	path(MESHD:"Alzheimer Disease") association p(HGNC:PRNP)
pmid:23577068	path(MESHD:"Alzheimer Disease") association p(HGNC:PRNP)
pmid:20127045	path(MESHD:"Alzheimer Disease") association bp(GOBP:endocytosis)
pmid:20097758	path(MESHD:"Alzheimer Disease") association p(HGNC:ATXN1)
pmid:21389115	path(MESHD:"Alzheimer Disease") increases act(p(HGNC:CDK5), ma(kin))
pmid:14673212	path(MESHD:"Alzheimer Disease") association act(p(HGNC:CDK5), ma(kin))
pmid:11181841	path(MESHD:"Alzheimer Disease") association p(HGNC:CDK5)
pmid:21393248	path(MESHD:"Alzheimer Disease") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:PRNP))
pmid:11489281	path(MESHD:"Alzheimer Disease") association complex(p(HGNC:APP), p(HGNC:PSEN1))
pmid:11337355	path(MESHD:"Alzheimer Disease") association p(HGNC:APBB1)
pmid:19038340	path(MESHD:"Alzheimer Disease") association p(SFAM:"GSK3 Family")
pmid:15975028	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:AGER)
PubMed Central:PMC3981768	path(MESHD:"Alzheimer Disease") association a(HBP:"amyloid-beta aggregates")
pmid:24586443	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:S100A9)
pmid:24874542	path(MESHD:"Alzheimer Disease") positiveCorrelation p(MGI:Il1b)
pmid:18628954	path(MESHD:"Alzheimer Disease") positiveCorrelation g(HGNC:APP, gmod(Me))
pmid:18628954	path(MESHD:"Alzheimer Disease") positiveCorrelation g(HGNC:BACE1, gmod(Me))
pmid:22223749	path(MESHD:"Alzheimer Disease") association bp(HBP:amyloidogenesis)
pmid:22223749	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:RANBP9)
pmid:24821282	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:PTPA)
pmid:12890786	path(MESHD:"Alzheimer Disease") positiveCorrelation bp(GOBP:"apoptotic process")
pmid:23164821	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:EGR1)
pmid:21969301	path(MESHD:"Alzheimer Disease") association p(HGNC:EGR1)
pmid:14585504	path(MESHD:"Alzheimer Disease") association p(HGNC:EGR1)
pmid:26880631	path(MESHD:"Alzheimer Disease") association p(HGNC:DKK1)
pmid:24883305	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:DKK1)
pmid:23261660	path(MESHD:"Alzheimer Disease") association p(HGNC:DKK1)
pmid:12094909	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:CAT)
pmid:24262633	path(MESHD:"Alzheimer Disease") association act(p(HGNC:NFE2L2))
pmid:24262633	path(MESHD:"Alzheimer Disease") negativeCorrelation act(p(HGNC:NFE2L2))
pmid:20064547	path(MESHD:"Alzheimer Disease") association p(HGNC:NFE2L2)
pmid:10967351	path(MESHD:"Alzheimer Disease") association p(HGNC:CTNNB1)
pmid:10967351	path(MESHD:"Alzheimer Disease") association p(HGNC:GSK3B)
pmid:15314261	path(MESHD:"Alzheimer Disease") association p(HGNC:GSK3B)
pmid:17389597	path(MESHD:"Alzheimer Disease") association act(p(HGNC:GSK3B))
pmid:17049785	path(MESHD:"Alzheimer Disease") decreases bp(PTS:"Insulin receptor signaling pathway")
pmid:15314261	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:GSK3B, pmod(Ph, Ser, 9))
pmid:15773910	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:GSK3B, pmod(Ph, Ser, 9))
pmid:15314261	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:CTNNB1, pmod(Ph))
pmid:15773910	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:MTOR, pmod(Ph, Ser, 2448))
pmid:21903077	path(MESHD:"Alzheimer Disease") association bp(GOBP:"inflammatory response")
pmid:18715507	path(MESHD:"Alzheimer Disease") positiveCorrelation bp(GOBP:"inflammatory response")
pmid:20413894	path(MESHD:"Alzheimer Disease") association bp(GOBP:"inflammatory response")
pmid:22441986	path(MESHD:"Alzheimer Disease") positiveCorrelation bp(GOBP:"inflammatory response")
pmid:11755016	path(MESHD:"Alzheimer Disease") positiveCorrelation a(MESH:D017628)
pmid:19801956	path(MESHD:"Alzheimer Disease") association m(HGNC:MIR146A)
pmid:21640790	path(MESHD:"Alzheimer Disease") increases m(HGNC:MIR590)
pmid:19734902	path(MESHD:"Alzheimer Disease") association g(HGNC:ANXA1)
pmid:23727898	path(MESHD:"Alzheimer Disease") increases p(HGNC:ALOX5)
pmid:18678882	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:ALOX5)
pmid:21246057	path(MESHD:"Alzheimer Disease") negativeCorrelation a(CHEBI:"protectin D1")
pmid:20413894	path(MESHD:"Alzheimer Disease") positiveCorrelation bp(GOBP:"astrocyte activation")
pmid:21143158	path(MESHD:"Alzheimer Disease") positiveCorrelation bp(GOBP:"cytokine production involved in inflammatory response")
pmid:22441986	path(MESHD:"Alzheimer Disease") increases bp(GOBP:"cytokine production involved in inflammatory response")
pmid:22441986	path(MESHD:"Alzheimer Disease") association bp(GOBP:"cytokine production involved in inflammatory response")
pmid:18938162	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:CD200)
pmid:18938162	path(MESHD:"Alzheimer Disease") negativeCorrelation r(HGNC:CD200)
pmid:18938162	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:CD200R1)
pmid:18938162	path(MESHD:"Alzheimer Disease") negativeCorrelation r(HGNC:CD200R1)
pmid:20413894	path(MESHD:"Alzheimer Disease") positiveCorrelation bp(GOBP:"microglial cell activation")
pmid: 26517285	path(MESHD:"Alzheimer Disease") negativeCorrelation bp(GOBP:"microglial cell activation")
pmid:24694234	path(MESHD:"Alzheimer Disease") association bp(HBP:neuroinflammation)
pmid:24863743	path(MESHD:"Alzheimer Disease") positiveCorrelation bp(HBP:neuroinflammation)
pmid:26836182	path(MESHD:"Alzheimer Disease") positiveCorrelation bp(HBP:neuroinflammation)
pmid:22441986	path(MESHD:"Alzheimer Disease") positiveCorrelation p(MGI:Lcn2)
pmid:22890100	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:CHI3L1)
pmid:21035623	path(MESHD:"Alzheimer Disease") increases p(HGNC:CHI3L1)
pmid:17005052	path(MESHD:"Alzheimer Disease") increases r(HGNC:ARG1)
pmid:17005052	path(MESHD:"Alzheimer Disease") increases r(HGNC:MRC1)
pmid:17005052	path(MESHD:"Alzheimer Disease") increases r(HGNC:TNF)
pmid:17005052	path(MESHD:"Alzheimer Disease") increases r(HGNC:CHI3L1)
pmid:17005052	path(MESHD:"Alzheimer Disease") increases r(HGNC:CHI3L2)
pmid:26783546	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:NRGN)
pmid:24663666	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:TREM2, var("p.Arg47His"))
pmid:24355566	path(MESHD:"Alzheimer Disease") association p(HGNC:TREM2)
pmid:23627755	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:IL6)
pmid:22536436	path(MESHD:"Alzheimer Disease") positiveCorrelation a(CHEBI:glucocorticoid)
pmid:22115781	path(MESHD:"Alzheimer Disease") positiveCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:15094078	path(MESHD:"Alzheimer Disease") association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:19885299	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:INS)
pmid:19885299	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:INS)
pmid:19519303	path(MESHD:"Alzheimer Disease") increases p(HGNC:INS)
pmid:19519303	path(MESHD:"Alzheimer Disease") decreases p(HGNC:INS)
pmid:19383491	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:INS)
pmid:19383491	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:INS)
pmid:12185156	path(MESHD:"Alzheimer Disease") association act(p(HGNC:INS))
pmid:22142155	path(MESHD:"Alzheimer Disease") decreases p(HGNC:INS)
pmid:19885299	path(MESHD:"Alzheimer Disease") association bp(GOBP:"negative regulation of insulin-like growth factor receptor signaling pathway")
pmid:19885299	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:IGF1)
pmid:19531281	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:IGF1)
pmid:19885299	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:IGF1R)
pmid:21916834	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:IGF1R)
pmid:19885299	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:MAPT)
pmid:12428805	path(MESHD:"Alzheimer Disease") association p(HGNC:MAPT)
pmid:15686969	path(MESHD:"Alzheimer Disease") association p(HGNC:MAPT)
pmid:3122646	path(MESHD:"Alzheimer Disease") increases tloc(p(HGNC:MAPT), fromLoc(GOCC:axon), toLoc(GOCC:"cell body"))
pmid:19885299	path(MESHD:"Alzheimer Disease") negativeCorrelation bp(MESHPP:"Energy Metabolism")
pmid:19885299	path(MESHD:"Alzheimer Disease") positiveCorrelation bp(HBP:"mitochondrial dysfunction")
pmid:19885299	path(MESHD:"Alzheimer Disease") association g(HGNC:ENPP1)
pmid:19885299	path(MESHD:"Alzheimer Disease") association g(HGNC:INSR)
pmid:14976144	path(MESHD:"Alzheimer Disease") negativeCorrelation act(complex(p(HGNC:CDK5), p(HGNC:CDK5R1)))
pmid:19519303	path(MESHD:"Alzheimer Disease") negativeCorrelation bp(GOBP:"insulin receptor signaling pathway")
pmid:19519303	path(MESHD:"Alzheimer Disease") negativeCorrelation bp(GOBP:"insulin-like growth factor receptor signaling pathway")
pmid:19519303	path(MESHD:"Alzheimer Disease") negativeCorrelation r(HGNC:INS)
pmid:19519303	path(MESHD:"Alzheimer Disease") negativeCorrelation r(HGNC:INSR)
pmid:19519303	path(MESHD:"Alzheimer Disease") decreases act(r(HGNC:INSR))
pmid:19519303	path(MESHD:"Alzheimer Disease") negativeCorrelation bp(GOBP:"regulation of protein tyrosine kinase activity")
pmid:19519303	path(MESHD:"Alzheimer Disease") negativeCorrelation r(HGNC:IGF1)
pmid:19519303	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:IRS1)
pmid:19519303	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:IRS2)
pmid:16399206	path(MESHD:"Alzheimer Disease") negativeCorrelation act(p(HGNC:IDE))
pmid:19383491	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:IDE)
pmid:21916834	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:INSR)
pmid:22142155	path(MESHD:"Alzheimer Disease") decreases p(HGNC:INSR)
pmid:12185156	path(MESHD:"Alzheimer Disease") association p(HGNC:PIK3R1, var("p.Met326Ile"))
pmid:21598254	path(MESHD:"Alzheimer Disease") negativeCorrelation bp(GOBP:"insulin receptor signaling pathway via phosphatidylinositol 3-kinase")
pmid:18411275	path(MESHD:"Alzheimer Disease") association complex(p(HGNC:APP, frag("672_713")), p(HGNC:IDE))
pmid:21537460	path(MESHD:"Alzheimer Disease") negativeCorrelation bp(GOBP:"type B pancreatic cell proliferation")
pmid:22115781	path(MESHD:"Alzheimer Disease") positiveCorrelation path(MESHD:Obesity)
pmid:21321400	path(MESHD:"Alzheimer Disease") association act(p(HGNC:HEXB))
pmid:23279143	path(MESHD:"Alzheimer Disease") association g(DBSNP:rs7907690)
pmid:21916834	path(MESHD:"Alzheimer Disease") negativeCorrelation p(SFAM:"IRS Family")
pmid:24324435	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:IGFBP2)
pmid:22142155	path(MESHD:"Alzheimer Disease") association path(MESHD:"Insulin Resistance")
pmid:24324435	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:IGF2)
pmid:18191876	path(MESHD:"Alzheimer Disease") association g(DBSNP:rs669)
pmid:18191876	path(MESHD:"Alzheimer Disease") association p(HGNC:OLR1)
pmid:18191876	path(MESHD:"Alzheimer Disease") association p(HGNC:OLR1)
pmid:22496686	path(MESHD:"Alzheimer Disease") association act(p(HGNC:LRP8))
pmid:21873229	path(MESHD:"Alzheimer Disease") association complex(p(HGNC:APOE), p(HGNC:APP, frag("672_713")))
pmid: 21543606	path(MESHD:"Alzheimer Disease") association g(DBSNP:rs11136000)
pmid:17975299	path(MESHD:"Alzheimer Disease") association g(HGNC:SORL1)
pmid:14970312	path(MESHD:"Alzheimer Disease") association bp(MESHPP:"Oxidative Stress")
pmid:17316694	path(MESHD:"Alzheimer Disease") association bp(MESHPP:"Oxidative Stress")
pmid:23653222	path(MESHD:"Alzheimer Disease") association bp(MESHPP:"Oxidative Stress")
pmid:14970312	path(MESHD:"Alzheimer Disease") association bp(GOBP:"cholesterol metabolic process")
pmid:21709374	path(MESHD:"Alzheimer Disease") association g(DBSNP:rs1050283)
pmid:18191876	path(MESHD:"Alzheimer Disease") association g(DBSNP:rs1050283)
pmid:18191876	path(MESHD:"Alzheimer Disease") association g(DBSNP:rs12316150)
pmid:21676498	path(MESHD:"Alzheimer Disease") positiveCorrelation r(HGNC:APOE)
pmid:21676498	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:LRP1)
pmid:23279143	path(MESHD:"Alzheimer Disease") association p(HGNC:SORCS1)
pmid: 21543606	path(MESHD:"Alzheimer Disease") decreases a(NIFT:"White matter")
pmid:14970312	path(MESHD:"Alzheimer Disease") association bp(GOBP:"sphingolipid metabolic process")
pmid:15255951	path(MESHD:"Alzheimer Disease") increases p(HGNC:MPO)
pmid:15255951	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:MPO)
pmid:24217274	path(MESHD:"Alzheimer Disease") increases p(HGNC:MPO)
pmid:19059911	path(MESHD:"Alzheimer Disease") increases p(HGNC:MPO)
pmid:12946561	path(MESHD:"Alzheimer Disease") association p(HGNC:MPO)
pmid:22710270	path(MESHD:"Alzheimer Disease") association g(HGNC:CADPS2)
pmid:22710270	path(MESHD:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs3757536)
pmid:21903077	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:NOS2)
pmid:21903077	path(MESHD:"Alzheimer Disease") increases p(HGNC:NOS2)
pmid:8879214	path(MESHD:"Alzheimer Disease") decreases p(HGNC:TGFB1)
pmid:19885299	path(MESHD:"Alzheimer Disease") association g(HGNC:NOS3)
pmid:17553629	path(MESHD:"Alzheimer Disease") negativeCorrelation a(CHEBI:"nitric oxide")
pmid:15016421	path(MESHD:"Alzheimer Disease") association a(CHEBI:"nitric oxide")
pmid:22512552	path(MESHD:"Alzheimer Disease") positiveCorrelation a(CHEBI:"nitric oxide")
pmid:16813604	path(MESHD:"Alzheimer Disease") association p(HGNC:NOS3)
pmid:16813604	path(MESHD:"Alzheimer Disease") association p(HGNC:NOS3, var("p.Glu298Asp"))
pmid:16813604	path(MESHD:"Alzheimer Disease") association p(HGNC:NOS3, var("p.Glu298Asp"))
pmid:11556547	path(MESHD:"Alzheimer Disease") positiveCorrelation g(HGNC:ASS1)
pmid:11556547	path(MESHD:"Alzheimer Disease") positiveCorrelation g(HGNC:NOS2)
pmid:11556547	path(MESHD:"Alzheimer Disease") positiveCorrelation g(HGNC:NOS2)
pmid:11556547	path(MESHD:"Alzheimer Disease") positiveCorrelation g(HGNC:GFAP)
pmid:15639314	path(MESHD:"Alzheimer Disease") negativeCorrelation a(CHEBI:probucol)
pmid:22382662	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:SYVN1)
pmid:23022416	path(MESHD:"Alzheimer Disease") association composite(g(DBSNP:rs3818361), g(DBSNP:rs429358))
pmid:21172309	path(MESHD:"Alzheimer Disease") negativeCorrelation m(HGNC:"MIR101-1")
pmid:21214928	path(MESHD:"Alzheimer Disease") decreases p(HGNC:ADAM10)
pmid:16364209	path(MESHD:"Alzheimer Disease") negativeCorrelation a(CHEBI:melatonin)
pmid:24987467	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:ACE)
pmid:17973905	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:ACE)
pmid:17973905	path(MESHD:"Alzheimer Disease") positiveCorrelation act(p(HGNC:ACE))
pmid:17112471	path(MESHD:"Alzheimer Disease") association p(HGNC:ADAM19)
pmid:12802175	path(MESHD:"Alzheimer Disease") association p(HGNC:NOTCH2)
pmid:21872584	path(MESHD:"Alzheimer Disease") association p(HGNC:NOTCH2)
pmid:20117143	path(MESHD:"Alzheimer Disease") association p(HGNC:NOTCH2)
pmid:19789989	path(MESHD:"Alzheimer Disease") association p(HGNC:NOTCH2)
pmid:17316694	path(MESHD:"Alzheimer Disease") association a(CHEBI:"reactive oxygen species")
pmid:17316694	path(MESHD:"Alzheimer Disease") association act(a(MESHCS:Mitochondria))
pmid:10363952	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:BLMH)
pmid:17426120	path(MESHD:"Alzheimer Disease") association p(HGNC:OGG1, var("p.Ala53Thr"))
pmid:17426120	path(MESHD:"Alzheimer Disease") association p(HGNC:OGG1, var("p.Ala288Val"))
pmid:19519303	path(MESHD:"Alzheimer Disease") negativeCorrelation act(p(HGNC:PPP2CA))
pmid:20660113	path(MESHD:"Alzheimer Disease") negativeCorrelation m(HGNC:MIR15A)
pmid:16504486	path(MESHD:"Alzheimer Disease") association complex(GOCC:"neurofibrillary tangle")
pmid:21666500	path(MESHD:"Alzheimer Disease") negativeCorrelation bp(GOBP:"regulation of cell cycle")
pmid:15773910	path(MESHD:"Alzheimer Disease") negativeCorrelation p(HGNC:CDKN1B)
pmid:15773910	path(MESHD:"Alzheimer Disease") positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 214))
pmid:22496686	path(MESHD:"Alzheimer Disease") increases complex(p(HGNC:APP), p(HGNC:GRB2), p(HGNC:SHC1))
pmid:24808823	path(MESHD:"Alzheimer Disease") positiveCorrelation p(MGI:Ttbk1)
pmid:24808823	path(MESHD:"Alzheimer Disease") positiveCorrelation p(MGI:Ttbk1)
pmid:17096857	path(MESHD:"Diabetes Mellitus, Type 2") association p(HGNC:BCHE)
pmid:17096857	path(MESHD:"Diabetes Mellitus, Type 2") association p(HGNC:ACHE)
pmid:23713771	path(MESHD:"Diabetes Mellitus, Type 2") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:IAPP))
pmid:22107728	path(MESHD:"Diabetes Mellitus, Type 2") association g(DBSNP:rs2251101)
pmid:22115781	path(MESHD:"Diabetes Mellitus, Type 2") positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:15094078	path(MESHD:"Diabetes Mellitus, Type 2") association path(MESHD:"Alzheimer Disease")
pmid:19885299	path(MESHD:"Diabetes Mellitus, Type 2") positiveCorrelation bp(MESHPP:"Insulin Resistance")
pmid:23627755	path(MESHD:"Diabetes Mellitus, Type 2") association bp(MESHPP:"Insulin Resistance")
pmid:19885299	path(MESHD:"Diabetes Mellitus, Type 2") positiveCorrelation bp(MESHPP:"Oxidative Stress")
pmid:17316694	path(MESHD:"Diabetes Mellitus, Type 2") association bp(MESHPP:"Oxidative Stress")
pmid:19885299	path(MESHD:"Diabetes Mellitus, Type 2") negativeCorrelation bp(GOBP:cognition)
pmid:19885299	path(MESHD:"Diabetes Mellitus, Type 2") increases p(SFAM:"IL1 Family")
pmid:19885299	path(MESHD:"Diabetes Mellitus, Type 2") increases p(HGNC:TNF)
pmid:19885299	path(MESHD:"Diabetes Mellitus, Type 2") positiveCorrelation path(MESHD:"Cerebrovascular Disorders")
pmid:22236693	path(MESHD:"Diabetes Mellitus, Type 2") association g(RGD:Ngfr)
pmid:19519303	path(MESHD:"Diabetes Mellitus, Type 2") association path(MESHD:"Glucose Intolerance")
pmid:19519303	path(MESHD:"Diabetes Mellitus, Type 2") association p(HGNC:IRS1, var("p.Gly972Arg"))
pmid:23627755	path(MESHD:"Diabetes Mellitus, Type 2") positiveCorrelation p(HGNC:IL6)
pmid:23627755	path(MESHD:"Diabetes Mellitus, Type 2") positiveCorrelation complex(GOCC:"neurofibrillary tangle")
pmid:19383491	path(MESHD:"Diabetes Mellitus, Type 2") positiveCorrelation p(RGD:Pomc)
pmid:19383491	path(MESHD:"Diabetes Mellitus, Type 2") positiveCorrelation a(CHEBI:cortisol)
pmid:20061608	path(MESHD:"Diabetes Mellitus, Type 2") association p(HGNC:APP, frag("672_713"))
pmid:21598254	path(MESHD:"Diabetes Mellitus, Type 2") negativeCorrelation bp(GOBP:"insulin receptor signaling pathway via phosphatidylinositol 3-kinase")
pmid:21537460	path(MESHD:"Diabetes Mellitus, Type 2") negativeCorrelation bp(GOBP:"type B pancreatic cell proliferation")
pmid:21321400	path(MESHD:"Diabetes Mellitus, Type 2") association act(p(HGNC:HEXB))
pmid:21321400	path(MESHD:"Diabetes Mellitus, Type 2") increases p(HGNC:HEXB)
pmid:21321400	path(MESHD:"Diabetes Mellitus, Type 2") association path(MESHD:Dementia)
pmid:21321400	path(MESHD:"Diabetes Mellitus, Type 2") increases p(HGNC:GLB1)
pmid:24652830	path(MESHD:"Diabetes Mellitus, Type 2") negativeCorrelation a(CHEBI:"2-deoxy-2-((18)F)fluoro-D-glucopyranose")
pmid:24652830	path(MESHD:"Diabetes Mellitus, Type 2") positiveCorrelation a(CHEBI:"2-deoxy-2-((18)F)fluoro-D-glucopyranose")
pmid:23279143	path(MESHD:"Diabetes Mellitus, Type 2") association g(DBSNP:rs7907690)
pmid:19659459	path(MESHD:"Diabetes Mellitus, Type 2") negativeCorrelation act(p(HGNC:OGT))
pmid:19659459	path(MESHD:"Diabetes Mellitus, Type 2") decreases act(p(HGNC:OGT))
pmid:19659459	path(MESHD:"Diabetes Mellitus, Type 2") negativeCorrelation p(HGNC:MAPT, pmod(OGlyco))
pmid:19659459	path(MESHD:"Diabetes Mellitus, Type 2") association p(HGNC:MAPT, pmod(Ph))
pmid:19659459	path(MESHD:"Diabetes Mellitus, Type 2") positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:19659459	path(MESHD:"Diabetes Mellitus, Type 2") decreases bp(GOBP:"glucose import")
pmid:19659459	path(MESHD:"Diabetes Mellitus, Type 2") decreases bp(GOBP:"glucose metabolic process")
pmid:19383491	path(MESHD:"Diabetes Mellitus, Type 2") negativeCorrelation p(HGNC:IDE)
pmid:23279143	path(MESHD:"Diabetes Mellitus, Type 2") association p(HGNC:SORCS1)
pmid:17553629	path(MESHD:"Diabetes Mellitus, Type 2") negativeCorrelation a(CHEBI:"nitric oxide")
pmid:17316694	path(MESHD:"Diabetes Mellitus, Type 2") association act(a(MESHCS:Mitochondria))
pmid:17553629	path(MESHD:Inflammation) negativeCorrelation a(CHEBI:acetylcholine)
pmid:23040664	path(MESHD:Inflammation) association path(MESHD:"Alzheimer Disease")
pmid:20308780	path(MESHD:Inflammation) association path(MESHD:"Alzheimer Disease")
pmid:18554520	path(MESHD:Inflammation) association path(MESHD:"Alzheimer Disease")
pmid:20157512	path(MESHD:Inflammation) association a(CHEBI:"amyloid-beta")
pmid:24262633	path(MESHD:Inflammation) association act(p(HGNC:NFE2L2))
pmid:24262633	path(MESHD:Inflammation) association act(p(HGNC:GSK3B))
pmid:19885299	path(MESHD:Inflammation) association a(MESH:D001253)
pmid:19885299	path(MESHD:Inflammation) association a(MESH:D017628)
pmid:19885299	path(MESHD:Inflammation) association r(HGNC:APP)
pmid:24529528	path(MESHD:Inflammation) negativeCorrelation bp(GOBP:"insulin receptor signaling pathway")
pmid:24529528	path(MESHD:Inflammation) decreases act(a(MESH:D009474))
pmid:24386594	path(MESHD:Inflammation) association p(HGNC:ADIPOQ)
pmid:22013558	path(MESHD:Inflammation) association a(MESHC:cerebrolysin)
pmid:21329555	path(MESHD:Inflammation) association complex(GOCC:"NF-kappaB complex")
pmid:23254638	path(MESHD:Inflammation) association a(CHEBI:"S-nitrosoglutathione")
pmid:15255951	path(MESHD:Inflammation) association p(HGNC:MPO)
pmid:17316167	path(MESHD:Inflammation) association p(HGNC:SPP1)
pmid:17316167	path(MESHD:Inflammation) association path(MESHD:"Neurodegenerative Diseases")
pmid:24262633	path(MESHD:Inflammation) association act(p(HGNC:MAPK14))
pmid:18554520	path(MESHD:Inflammation) association path(MESHD:"Multiple Sclerosis")
pmid:18554520	path(MESHD:Inflammation) association path(MESHD:"Parkinson Disease")
pmid:18554520	path(MESHD:Inflammation) association a(CHEBI:"reactive oxygen species")
pmid:18554520	path(MESHD:Inflammation) association p(HGNC:TNF)
pmid:20634595	path(MESHD:Inflammation) association p(HGNC:EDN1)
pmid:24960578	path(MESHD:Inflammation) decreases bp(GOBP:"synapse assembly")
pmid:24960578	path(MESHD:Inflammation) decreases bp(GOBP:cognition)
pmid:24960578	path(MESHD:Inflammation) increases bp(GOBP:"neuron death")
pmid:23468966	path(MESHD:Inflammation) association p(MGI:Il17a)
pmid:20937084	path(MESHD:Inflammation) association a(CHEBI:bradykinin)
pmid:20937084	path(MESHD:Inflammation) association a(CHEBI:somatostatin)
pmid:20937084	path(MESHD:Inflammation) association p(MGI:Sst)
pmid:20937084	path(MESHD:Inflammation) association p(SFAM:"EDN Family")
pmid:21035623	path(MESHD:Inflammation) positiveCorrelation p(HGNC:CHI3L1)
pmid:20092570	a(ADO:"presence_of_neuritic_plaque") positiveCorrelation p(MGI:Bace1)
pmid:7695621	a(ADO:"senile_plaque") association p(HGNC:APOE)
pmid:7695621	a(ADO:"senile_plaque") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE))
pmid:20849853	a(CHEBI:"(-)-epigallocatechin 3-gallate") increases p(HGNC:ADAM10)
pmid:20849853	a(CHEBI:"(-)-epigallocatechin 3-gallate") decreases a(CHEBI:"amyloid-beta")
pmid:20849853	a(CHEBI:"(-)-epigallocatechin 3-gallate") increases bp(GOBP:cognition)
pmid:24874542	a(CHEBI:"3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonic acid)") association p(SFAM:"IL1 Family")
pmid:24874542	a(CHEBI:"3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonic acid)") association path(MESHD:"Plaque, Amyloid")
pmid:19245828	a(CHEBI:"8-hydroxy-2'-deoxyguanosine") biomarkerFor bp(MESHPP:"Oxidative Stress")
pmid:16484331	a(CHEBI:"8-hydroxy-2'-deoxyguanosine") negativeCorrelation act(p(RGD:Ogg1))
pmid:20720123	a(CHEBI:"EC 3.4.23.46 (memapsin 2) inhibitor") decreases act(p(HGNC:BACE1), ma(pep))
pmid:25698445	a(CHEBI:"amyloid-beta polypeptide 42") increases act(p(HGNC:CFL1))
pmid:25698445	a(CHEBI:"amyloid-beta polypeptide 42") decreases p(HGNC:VCL)
pmid:25698445	a(CHEBI:"amyloid-beta polypeptide 42") increases bp(GOBP:"apoptotic process")
pmid:20847424	a(CHEBI:"amyloid-beta polypeptide 42") increases a(CHEBI:"reactive oxygen species")
pmid:25698445	a(CHEBI:"amyloid-beta polypeptide 42") increases a(CHEBI:"reactive oxygen species")
pmid:20847424	a(CHEBI:"amyloid-beta polypeptide 42") increases bp(MESHPP:"Oxidative Stress")
pmid:20847424	a(CHEBI:"amyloid-beta polypeptide 42") association bp(MESHPP:"Oxidative Stress")
pmid:20847424	a(CHEBI:"amyloid-beta polypeptide 42") association bp(GOBP:"calcium ion homeostasis")
pmid:19765582	a(CHEBI:"bis(7)-tacrine") decreases act(p(HGNC:BACE1), ma(pep))
pmid:19765582	a(CHEBI:"bis(7)-tacrine") decreases a(CHEBI:"amyloid-beta")
pmid:22844264	act(a(CHEBI:"copper(2+)")) increases p(HGNC:APP, frag("672_713"))
pmid:20052565	a(CHEBI:"galactosylceramide sulfate") association path(MESHD:"Alzheimer Disease")
pmid:20052565	a(CHEBI:"galactosylceramide sulfate") association p(HGNC:APP)
pmid:20052565	a(CHEBI:"galactosylceramide sulfate") increases complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE))
pmid:20052565	a(CHEBI:"galactosylceramide sulfate") association p(HGNC:APP, frag("672_713"))
pmid:14530380	a(CHEBI:"heparan sulfate") association act(p(HGNC:BACE1), ma(pep))
pmid:19090990	a(CHEBI:"iron(3+)") regulates r(HGNC:APP)
pmid:19090990	a(CHEBI:"iron(3+)") increases a(CHEBI:"amyloid-beta")
pmid:22764079	a(CHEBI:"lead atom") increases g(HGNC:APP, gmod(Me))
pmid:15673661	a(CHEBI:"lead atom") increases p(MGI:App)
pmid:16484331	a(CHEBI:"lead(0)") increases a(CHEBI:"8-hydroxy-2'-deoxyguanosine")
pmid:16484331	a(CHEBI:"lead(0)") increases a(CHEBI:"amyloid-beta")
pmid:16484331	a(CHEBI:"lead(0)") increases act(p(RGD:Ogg1))
pmid:21253550	a(CHEBI:"magnesium(2+)") increases act(complex(SCOMP:"gamma Secretase Complex"), ma(pep))
pmid:24769037	a(CHEBI:"monosodium glutamate") increases a(CHEBI:"amyloid-beta")
pmid:24769037	a(CHEBI:"monosodium glutamate") increases p(HGNC:APP, frag("672_713"))
pmid:15232608	a(CHEBI:"nitric oxide") increases bp(GOBP:"neuron apoptotic process")
pmid:21903077	a(CHEBI:"nitric oxide") association bp(GOBP:"neuronal signal transduction")
pmid:22550546	a(CHEBI:"nitric oxide") regulates p(HGNC:APP)
pmid:15126337	a(CHEBI:"nitric oxide") association p(HGNC:AIFM1)
pmid:13678430	a(CHEBI:"nitric oxide") decreases p(HGNC:CD86)
pmid:17553629	a(CHEBI:"nitric oxide") negativeCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:17553629	a(CHEBI:"nitric oxide") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:15016421	a(CHEBI:"nitric oxide") association path(MESHD:"Alzheimer Disease")
pmid:22512552	a(CHEBI:"nitric oxide") positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:24948534	a(CHEBI:"nitric oxide") association p(HGNC:CASR)
pmid:22512552	a(CHEBI:"nitric oxide") association bp(MESHPP:"Synaptic Transmission")
pmid:22512552	a(CHEBI:"nitric oxide") association bp(GOBP:"regulation of blood pressure")
pmid:22512552	a(CHEBI:"nitric oxide") positiveCorrelation path(MESHD:"Huntington Disease")
pmid:22512552	a(CHEBI:"nitric oxide") positiveCorrelation path(MESHD:"Amyotrophic Lateral Sclerosis")
pmid:24817841	a(CHEBI:"nitric oxide") increases bp(GOBP:"regulation of vasodilation")
pmid:24817841	a(CHEBI:"nitric oxide") increases bp(GOBP:"cell communication")
pmid:24817841	a(CHEBI:"nitric oxide") increases bp(GOBP:"cellular response to nitrosative stress")
pmid:16054114	a(CHEBI:"nitric oxide") increases path(GOBP:aging)
pmid:21903077	a(CHEBI:"nitrogen dioxide") increases p(HGNC:APP, var("p.Asn10Tyr"))
pmid:15232608	a(CHEBI:"reactive oxygen species") increases bp(GOBP:"neuron apoptotic process")
pmid:20847424	a(CHEBI:"reactive oxygen species") increases bp(GOBP:"neuron apoptotic process")
pmid:22523685	a(CHEBI:"reactive oxygen species") increases bp(GOBP:"neuron apoptotic process")
pmid:22523685	a(CHEBI:"reactive oxygen species") decreases bp(GOBP:"mitochondria-nucleus signaling pathway")
pmid:18554520	a(CHEBI:"reactive oxygen species") association path(MESHD:Inflammation)
pmid:18554520	a(CHEBI:"reactive oxygen species") association p(HGNC:MPO)
pmid:22523685	a(CHEBI:"reactive oxygen species") increases p(HGNC:APP, frag("672_713"))
pmid:22523685	a(CHEBI:"reactive oxygen species") increases bp(GOBP:"lipid oxidation")
pmid:22523685	a(CHEBI:"reactive oxygen species") increases bp(GOBP:"mitochondrion disassembly")
pmid:22523685	a(CHEBI:"reactive oxygen species") increases p(HGNC:MAPT, pmod(Ph))
pmid:20847424	a(CHEBI:"reactive oxygen species") decreases bp(GOBP:"long-term synaptic potentiation")
pmid:20847424	a(CHEBI:"reactive oxygen species") increases bp(GOBP:"apoptotic process")
pmid:19499146	a(CHEBI:"reactive oxygen species") increases tloc(p(HGNC:CYCS), fromLoc(MESH:D008928), toLoc(MESHCS:Cytosol))
pmid:17316694	a(CHEBI:"reactive oxygen species") association a(MESH:D008928)
pmid:17316694	a(CHEBI:"reactive oxygen species") association path(MESHD:"Alzheimer Disease")
pmid:21893081	a(CHEBI:"reactive oxygen species") increases bp(MESHPP:"Oxidative Stress")
pmid:23818595	a(CHEBI:"reactive oxygen species") increases act(p(MGI:Stk4))
pmid:17015226	a(CHEBI:"reactive oxygen species") decreases act(p(HGNC:SLC1A2))
pmid:23954639	a(CHEBI:"reactive oxygen species") increases p(HGNC:NOX4)
pmid:22055193	a(CHEBI:"reactive oxygen species") increases act(p(HGNC:ATM))
pmid:22055193	a(CHEBI:"reactive oxygen species") increases act(p(HGNC:TP53))
pmid:24619568	a(CHEBI:"reactive oxygen species") association a(CHEBI:"acetylsalicylic acid")
pmid:19245828	a(CHEBI:"reactive oxygen species") increases path(MESHPP:"DNA Damage")
pmid:19244175	a(CHEBI:"vitamin E") increases r(HGNC:APLP2)
pmid:12548636	a(CHEBI:"vitamin E") decreases p(MGI:Hspd1, pmod(GO:"GO:0018158"))
pmid:12548636	a(CHEBI:"vitamin E") decreases p(MGI:Vim, pmod(GO:"GO:0018158"))
pmid:12548636	a(CHEBI:"vitamin E") decreases bp(GOBP:"apoptotic process")
pmid:15566391	a(CHEBI:"vitamin E") increases r(HGNC:BIRC2)
pmid:19244175	a(CHEBI:"vitamin E") increases r(HGNC:LAMB2)
pmid:10658956	a(CHEBI:"vitamin E") decreases a(CHEBI:"reactive oxygen species")
pmid:10658956	a(CHEBI:"vitamin E") decreases bp(MESHPP:"Oxidative Stress")
pmid:10658956	a(CHEBI:"vitamin E") decreases bp(HBP:neurotoxicity)
pmid:23794448	a(CHEBI:Amylin) decreases deg(a(CHEBI:"amyloid-beta"))
pmid:24984171	a(CHEBI:Isorhynchophylline) decreases a(CHEBI:"amyloid-beta")
pmid:24984171	a(CHEBI:Isorhynchophylline) increases bp(GOBP:cognition)
pmid:24984171	a(CHEBI:Isorhynchophylline) increases bp(GOBP:"regulation of superoxide dismutase activity")
pmid:24984171	a(CHEBI:Isorhynchophylline) decreases a(CHEBI:"nitric oxide")
pmid:24984171	a(CHEBI:Isorhynchophylline) decreases p(HGNC:NOS2)
pmid:21994399	a(CHEBI:ceramide) increases a(CHEBI:"amyloid-beta")
pmid:21994399	a(CHEBI:ceramide) increases p(HGNC:APP, frag("672_713"))
pmid:14970312	a(CHEBI:ceramide) increases bp(GOBP:"neuron death")
pmid:18308724	a(CHEBI:cholesterol) association path(MESHD:"Alzheimer Disease")
pmid:12668899	a(CHEBI:cholesterol) association a(CHEBI:"amyloid-beta")
pmid:17495608	a(CHEBI:cholesterol) association a(CHEBI:"amyloid-beta")
pmid:17495608	a(CHEBI:cholesterol) association a(CHEBI:"amyloid-beta")
pmid:18308724	a(CHEBI:cholesterol) association a(CHEBI:"amyloid-beta")
pmid:20138836	a(CHEBI:cholesterol) association a(CHEBI:"amyloid-beta")
pmid:20580937	a(CHEBI:cholesterol) directlyIncreases g(HGNC:CLTC)
pmid:20580937	a(CHEBI:cholesterol) directlyIncreases bp(GOBP:"clathrin-dependent endocytosis")
pmid:20580937	a(CHEBI:cholesterol) directlyIncreases g(HGNC:DNM2)
pmid:20580937	a(CHEBI:cholesterol) directlyIncreases bp(GOBP:"positive regulation of endocytosis")
pmid:20580937	a(CHEBI:cholesterol) directlyIncreases g(HGNC:EPS15)
pmid:20580937	a(CHEBI:cholesterol) directlyIncreases g(HGNC:RAB5A)
pmid:21352095	a(CHEBI:cholesterol) increases a(HBP:"amyloid-beta aggregates")
pmid:21352095	a(CHEBI:cholesterol) association bp(HBP:amyloidogenesis)
pmid:22580286	a(CHEBI:cholesterol) association a(GOCC:endolysosome)
pmid:14970312	a(CHEBI:cholesterol) decreases a(CHEBI:"acyl-CoA")
pmid:20847424	a(CHEBI:cholesterol) increases deg(p(HGNC:APP))
pmid:20847424	a(CHEBI:cholesterol) increases r(HGNC:APP)
pmid:12668899	a(CHEBI:cholesterol) association p(HGNC:MAPT, pmod(Ph))
pmid:12668899	a(CHEBI:cholesterol) association bp(GOBP:"synapse maturation")
pmid:12668899	a(CHEBI:cholesterol) association path(MESHD:"Nerve Degeneration")
pmid:19237574	a(CHEBI:dorsomorphin) isA a(CHEBI:"EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitor")
pmid:19237574	a(CHEBI:dorsomorphin) decreases a(CHEBI:metformin)
pmid:19237574	a(CHEBI:dorsomorphin) decreases a(CHEBI:metformin)
pmid:19237574	a(CHEBI:dorsomorphin) decreases a(CHEBI:"amyloid-beta")
pmid:19237574	a(CHEBI:dorsomorphin) decreases a(CHEBI:"amyloid-beta")
pmid:19237574	a(CHEBI:dorsomorphin) decreases act(p(HGNC:BACE1), ma(tscript))
pmid:19237574	a(CHEBI:dorsomorphin) decreases r(HGNC:BACE1)
pmid:22402435	a(CHEBI:estrogen) increases act(p(HGNC:MMP2))
pmid:22402435	a(CHEBI:estrogen) increases act(p(HGNC:MMP9))
pmid:23261660	a(CHEBI:estrogen) decreases p(HGNC:DKK1)
pmid:23261660	a(CHEBI:estrogen) decreases path(MESHD:"Brain Ischemia")
pmid:23261660	a(CHEBI:estrogen) increases bp(GOBP:"Wnt signaling pathway")
pmid:19519303	a(CHEBI:estrogen) association bp(GOBP:"response to insulin")
pmid:21396986	act(a(CHEBI:estrogen)) increases bp(MESH:D000066829)
pmid:20067575	a(CHEBI:glycosaminoglycan) increases act(p(HGNC:BACE1), ma(pep))
pmid:16716081	a(CHEBI:heparin) increases act(p(HGNC:BACE1), ma(pep))
pmid:9152995	a(CHEBI:heparin) increases act(p(HGNC:BACE1), ma(pep))
pmid:9152995	a(CHEBI:heparin) increases a(CHEBI:"amyloid-beta")
pmid:15864339	a(CHEBI:isoprostane) increases a(CHEBI:"amyloid-beta")
pmid:19237574	a(CHEBI:metformin) increases act(p(SFAM:"PRKAA Family"))
pmid:19237574	a(CHEBI:metformin) increases a(CHEBI:"amyloid-beta")
pmid:19237574	a(CHEBI:metformin) increases a(CHEBI:"amyloid-beta")
pmid:19237574	a(CHEBI:metformin) causesNoChange deg(a(CHEBI:"amyloid-beta"))
pmid:19237574	a(CHEBI:metformin) increases a(CHEBI:"amyloid-beta")
pmid:19237574	a(CHEBI:metformin) increases act(p(HGNC:BACE1), ma(tscript))
pmid:19237574	a(CHEBI:metformin) increases act(p(HGNC:BACE1))
pmid:19237574	a(CHEBI:metformin) increases p(HGNC:BACE1)
pmid:19237574	a(CHEBI:metformin) increases act(p(HGNC:BACE1))
pmid:19237574	a(CHEBI:metformin) increases p(HGNC:APP, frag("672_713"))
pmid:19237574	a(CHEBI:metformin) increases p(HGNC:APP, frag("672_711"))
pmid:19237574	a(CHEBI:metformin) increases p(HGNC:APP)
pmid:19237574	a(CHEBI:metformin) decreases tloc(p(HGNC:APP), fromLoc(GOCC:intracellular), toLoc(GOCC:"cell surface"))
pmid:19237574	a(CHEBI:metformin) decreases p(HGNC:APP)
pmid:19237574	a(CHEBI:metformin) decreases tloc(p(HGNC:LRP1))
pmid:19237574	a(CHEBI:metformin) increases bp(GOBP:"response to insulin")
pmid:19237574	a(CHEBI:metformin) increases bp(GOBP:"glucose import")
pmid:19237574	a(CHEBI:metformin) decreases bp(GOBP:"glucose metabolic process")
pmid:19237574	a(CHEBI:metformin) causesNoChange bp(GOBP:"glucose metabolic process")
pmid:19237574	a(CHEBI:metformin) decreases act(a(MESH:D008928))
pmid:19237574	a(CHEBI:metformin) decreases act(p(HGNC:ADAM10))
pmid:19237574	a(CHEBI:metformin) causesNoChange p(HGNC:IDE)
pmid:19237574	a(CHEBI:metformin) causesNoChange p(HGNC:MME)
pmid:19237574	a(CHEBI:metformin) increases r(HGNC:BACE1)
pmid:19237574	a(CHEBI:metformin) causesNoChange bp(GOBP:"insulin receptor signaling pathway")
pmid:19237574	act(a(CHEBI:metformin)) increases p(SFAM:"PRKAA Family", pmod(Ph, Thr, 172))
pmid:19237574	act(a(CHEBI:metformin)) increases p(HGNC:ACACA, pmod(Ph))
pmid:21903077	a(CHEBI:peroxynitrite) increases p(HGNC:APP, var("p.Asn10Tyr"))
pmid:17869087	a(CHEBI:peroxynitrite) increases bp(GOBP:"apoptotic process")
pmid:22115781	a(CHEBI:quercetin) decreases bp(GOBP:"response to endoplasmic reticulum stress")
pmid:22523685	a(CHEBI:radical) positiveCorrelation p(HGNC:APP, frag("49_*"))
pmid:22523685	a(CHEBI:radical) negativeCorrelation p(HGNC:APP, frag("50_*"))
pmid:16179266	act(a(CHEBI:radical)) increases path(MESHD:"Brain Edema")
pmid:15295589	a(CHEBI:superoxide) directlyIncreases a(CHEBI:"hydrogen peroxide")
pmid:15864339	a(CHEBI:superoxide) increases a(CHEBI:isoprostane)
pmid:15325590	a(GOCC:autophagosome) increases a(CHEBI:"amyloid-beta")
PubMed Central:PMC3981768	a(HBP:"amyloid-beta aggregates") association path(MESHD:"Alzheimer Disease")
pmid:16624814	a(HBP:"sAPP-alpha") positiveCorrelation p(HGNC:ADAM10)
pmid:18397369	a(HBP:"sAPP-alpha") increases bp(MESHPP:Neuroprotection)
pmid:21214928	a(HBP:"sAPP-alpha") equivalentTo a(MESHC:"alpha-sAPP protein, human")
pmid:21799757	a(HBP:"sAPP-alpha") increases bp(MESH:D000066829)
pmid:21799757	a(HBP:"sAPP-alpha") increases bp(MESH:D000066829)
pmid:21214928	a(HBP:"sAPP-alpha") increases bp(GOBP:"regulation of neuronal synaptic plasticity")
pmid:21214928	a(HBP:"sAPP-alpha") increases bp(GOBP:"stem cell proliferation")
pmid:21214928	a(HBP:"sAPP-alpha") increases bp(GOBP:"central nervous system development")
pmid:21214928	a(HBP:"sAPP-alpha") decreases p(HGNC:CDK5)
pmid:21214928	a(HBP:"sAPP-alpha") increases a(MESH:D009474)
pmid:20883690	act(a(HBP:"sAPP-alpha")) increases bp(GOBP:"glial cell differentiation")
pmid:20883690	a(HBP:"sAPP-alpha") increases p(HGNC:STAT3, pmod(Ph))
pmid:20883690	a(HBP:"sAPP-alpha") increases act(p(FPLX:Notch))
pmid:20847424	a(MESH:D008928) association bp(MESHPP:"Oxidative Stress")
pmid:17316694	a(MESH:D008928) association a(CHEBI:"reactive oxygen species")
pmid:18297066	act(a(MESH:D009474)) positiveCorrelation p(HGNC:APOE)
pmid:9338779	act(a(MESH:D009474)) association complex(p(HGNC:APP, frag("672_713")), p(HGNC:HSD17B10))
pmid:20205643	a(MESH:D055017) association a(CHEBI:"amyloid-beta")
pmid:20847424	act(a(MESHC:"Ion Channels")) association p(HGNC:APP, frag("672_713"))
pmid:17424907	act(a(MESHCS:Mitochondria)) association a(CHEBI:"amyloid-beta")
pmid:17316694	act(a(MESHCS:Mitochondria)) association path(MESHD:"Alzheimer Disease")
pmid:17316694	act(a(MESHCS:Mitochondria)) association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:25678559	a(NIFT:"Clinical dementia rating") positiveCorrelation p(HGNC:APP)
pmid:26027813	a(NIFT:"Cortical Thickness") association a(CHEBI:"amyloid-beta")
pmid:25865441	a(NIFT:"Cortical Thickness") negativeCorrelation p(HGNC:CHI3L1)
pmid:25865441	a(NIFT:"Cortical Thickness") negativeCorrelation p(HGNC:CHI3L1)
pmid:26836182	a(NIFT:"Cortical Thickness") negativeCorrelation p(HGNC:CHI3L1)
pmid:26027813	a(NIFT:"Cortical Thinning") increases path(MESHD:"Alzheimer Disease")
pmid:20065247	a(NIFT:"Hippocampal atrophy") positiveCorrelation p(HGNC:APP)
pmid:25570489	a(NIFT:"Hippocampal atrophy") association p(HGNC:ESR1)
pmid:20100581	a(NIFT:"Hippocampal atrophy") association bp(GOBP:"apoptotic process")
pmid:25678559	a(NIFT:"Hippocampus volume") negativeCorrelation p(HGNC:APP)
pmid:25678559	a(NIFT:"Mini mental state exam") negativeCorrelation p(HGNC:APP)
pmid:16914869	bp(ADO:"loss_of_synapses") association p(HGNC:GSK3B)
pmid:19519303	bp(GOBP:"TOR signaling") association act(p(HGNC:GSK3B))
pmid:19519303	bp(GOBP:"TOR signaling") association act(p(HGNC:PPP2CA))
pmid:24270208	bp(GOBP:"Wnt signaling pathway") negativeCorrelation p(RGD:Dkk1)
pmid:18494933	bp(GOBP:"Wnt signaling pathway") positiveCorrelation p(HGNC:CTNNB1)
pmid:19885299	bp(GOBP:"Wnt signaling pathway") positiveCorrelation bp(MESH:D000066829)
pmid:10967351	bp(GOBP:"Wnt signaling pathway") association p(SFAM:"DVL Family")
pmid:10967351	bp(GOBP:"Wnt signaling pathway") association bp(GOBP:"brain development")
pmid:10967351	bp(GOBP:"Wnt signaling pathway") decreases path(MESHD:"Alzheimer Disease")
pmid:23164821	bp(GOBP:"Wnt signaling pathway, planar cell polarity pathway") positiveCorrelation path(MESHD:Tauopathies)
pmid:23164821	bp(GOBP:"Wnt signaling pathway, planar cell polarity pathway") increases p(HGNC:EGR1)
pmid:23164821	bp(GOBP:"Wnt signaling pathway, planar cell polarity pathway") increases p(HGNC:EGR1)
pmid:23164821	bp(GOBP:"Wnt signaling pathway, planar cell polarity pathway") increases p(HGNC:NAB2)
pmid:23164821	bp(GOBP:"Wnt signaling pathway, planar cell polarity pathway") increases p(HGNC:NAB2)
pmid:23164821	bp(GOBP:"Wnt signaling pathway, planar cell polarity pathway") increases p(HGNC:KLF10)
pmid:23164821	bp(GOBP:"Wnt signaling pathway, planar cell polarity pathway") increases p(HGNC:KLF10)
pmid:23164821	bp(GOBP:"Wnt signaling pathway, planar cell polarity pathway") isA bp(GOBP:"non-canonical Wnt signaling pathway")
pmid:22355794	bp(GOBP:"anterograde axonal transport") increases tloc(p(HGNC:APP))
pmid:22355794	bp(GOBP:"anterograde axonal transport") increases tloc(p(HGNC:APLP1))
pmid:22178568	bp(GOBP:"apoptotic process") positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:22178568	bp(GOBP:"apoptotic process") association m(HGNC:"MIR124-1")
pmid:11877420	bp(GOBP:"apoptotic process") association complex(p(HGNC:APBB1), p(HGNC:APP))
pmid:11877420	bp(GOBP:"apoptotic process") association complex(p(HGNC:APBA1), p(HGNC:APP))
pmid:11877420	bp(GOBP:"apoptotic process") association complex(p(HGNC:APP), p(HGNC:MAPK8IP1))
pmid:22496686	bp(GOBP:"apoptotic process") association bp(GOBP:"Notch signaling pathway")
pmid:22496686	bp(GOBP:"apoptotic process") association act(p(SFAM:"MAPK Erk1/2 Family"))
pmid:19499146	bp(GOBP:"apoptotic process") association a(MESHCS:Lysosomes)
pmid:22236693	bp(GOBP:"apoptotic process") negativeCorrelation p(HGNC:NTRK1)
pmid:17316167	bp(GOBP:"apoptotic process") association p(HGNC:SPP1)
pmid:17316167	bp(GOBP:"apoptotic process") association path(MESHD:"Neurodegenerative Diseases")
pmid:10371197	bp(GOBP:"apoptotic process") association p(HGNC:HSD17B10)
pmid:12890786	bp(GOBP:"apoptotic process") positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:20100581	bp(GOBP:"apoptotic process") association bp(GOBP:"microglial cell activation")
pmid:20100581	bp(GOBP:"apoptotic process") association a(NIFT:"Hippocampal atrophy")
pmid:10850726	bp(GOBP:"apoptotic process") increases act(p(HGNC:PRKCD, frag("?")))
pmid:17360687	bp(GOBP:"apoptotic process") association p(HGNC:CTNNB1, pmod(Ph))
pmid:17360687	bp(GOBP:"apoptotic process") association act(p(HGNC:GSK3B))
pmid:22496686	bp(GOBP:"apoptotic process") association composite(p(HGNC:PSEN1), p(HGNC:PSEN2))
pmid:22212405	bp(GOBP:"axonal transport") association a(CHEBI:"amyloid-beta")
pmid:22434822	bp(GOBP:"axonal transport") association a(CHEBI:"amyloid-beta")
pmid:22212405	bp(GOBP:"axonal transport") association act(p(HGNC:BDNF))
pmid:10967351	bp(GOBP:"brain development") association bp(GOBP:"Notch signaling pathway")
pmid:10967351	bp(GOBP:"brain development") association bp(GOBP:"Wnt signaling pathway")
pmid:10967351	bp(GOBP:"brain development") decreases bp(GOBP:"neuron apoptotic process")
pmid:22453989	bp(GOBP:"calcium ion homeostasis") association a(CHEBI:"amyloid-beta")
pmid:22122372	bp(GOBP:"calcium ion homeostasis") association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:18675468	bp(GOBP:"calcium ion homeostasis") negativeCorrelation bp(GOBP:"membrane lipid catabolic process")
pmid:20847424	bp(GOBP:"calcium ion homeostasis") association a(CHEBI:"amyloid-beta polypeptide 42")
pmid:19419557	bp(GOBP:"calcium-mediated signaling") association a(CHEBI:"amyloid-beta")
pmid:20847424	bp(GOBP:"calcium-mediated signaling") decreases bp(GOBP:"apoptotic process")
pmid:20847424	bp(GOBP:"calcium-mediated signaling") increases bp(GOBP:"negative regulation of neuron apoptotic process")
pmid:19419557	bp(GOBP:"calcium-mediated signaling") association p(HGNC:MAPT, pmod(Ph))
pmid:3691552	bp(GOBP:"canonical Wnt signaling pathway") decreases a(CHEBI:"amyloid-beta")
pmid:22496686	bp(GOBP:"cell cycle") association bp(GOBP:"neuron apoptotic process")
pmid:22496686	bp(GOBP:"cell cycle") increases p(HGNC:MAPT, pmod(Ph))
pmid:21389115	bp(GOBP:"cell death") association act(p(HGNC:CDK5), ma(kin))
pmid:16507903	bp(GOBP:"cell death") association p(HGNC:CDKN1A)
pmid:19918364	bp(GOBP:"cell death") association p(GFAM:"NF-kappa B complex subunits")
pmid:19918364	bp(GOBP:"cell death") association p(HGNC:WWOX)
pmid:19076431	bp(GOBP:"cell death") association path(MESHD:"Neurodegenerative Diseases")
pmid:19076431	bp(GOBP:"cell death") association path(MESHD:"Parkinson Disease")
pmid:19076431	bp(GOBP:"cell death") association path(MESHD:"Huntington Disease")
pmid:19076431	bp(GOBP:"cell death") association path(MESHD:"Amyotrophic Lateral Sclerosis")
pmid:19519303	bp(GOBP:"cell proliferation") association act(p(HGNC:INS))
pmid:19519303	bp(GOBP:"cell proliferation") association act(p(HGNC:IGF1))
pmid:22496686	bp(GOBP:"cell proliferation") association bp(GOBP:"Notch signaling pathway")
pmid:22355794	bp(GOBP:"cell-cell adhesion") association p(HGNC:APP)
pmid:22355794	bp(GOBP:"cell-matrix adhesion") association complex(p(HGNC:APP), p(HGNC:COL1A1))
pmid:22355794	bp(GOBP:"cell-matrix adhesion") association p(HGNC:APP)
pmid:22355794	bp(GOBP:"cell-matrix adhesion") association complex(p(HGNC:APP), p(HGNC:HDGF))
pmid:22355794	bp(GOBP:"cell-matrix adhesion") association complex(p(HGNC:APP), p(HGNC:LAMC1))
pmid:20385830	bp(GOBP:"chemical synaptic transmission") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:20385830	bp(GOBP:"chemical synaptic transmission") negativeCorrelation a(CHEBI:"amyloid-beta")
pmid:20847424	bp(GOBP:"chemical synaptic transmission") increases bp(GOBP:"neuron cellular homeostasis")
pmid:20847424	bp(GOBP:"chemical synaptic transmission") increases p(HGNC:BACE1)
pmid:20847424	bp(GOBP:"chemical synaptic transmission") increases p(HGNC:BACE2)
pmid:19383491	bp(GOBP:"chemical synaptic transmission") association bp(GOBP:"calcium ion import")
pmid:22496686	bp(GOBP:"chromosome segregation") association p(HGNC:APP)
pmid:22496686	bp(GOBP:"chromosome segregation") association p(HGNC:PSEN1)
pmid:22539346	bp(GOBP:"clathrin-dependent endocytosis") association p(HGNC:PICALM)
pmid:20580937	bp(GOBP:"clathrin-dependent endocytosis") directlyIncreases a(CHEBI:"amyloid-beta")
pmid:18650430	bp(GOBP:"cytokine metabolic process") association p(HGNC:APP)
pmid:26147761	bp(GOBP:"gamma-aminobutyric acid signaling pathway") increases a(CHEBI:"3',5'-cyclic AMP")
pmid:26147761	bp(GOBP:"gamma-aminobutyric acid signaling pathway") decreases bp(GOBP:"positive regulation of voltage-gated potassium channel activity")
pmid:22249458	bp(GOBP:"intrinsic apoptotic signaling pathway in response to oxidative stress") directlyIncreases p(HGNC:BACE1)
pmid:16687508	bp(GOBP:"intrinsic apoptotic signaling pathway in response to oxidative stress") association path(MESHD:"Alzheimer Disease")
pmid:19519303	bp(GOBP:"maintenance of permeability of blood-brain barrier") decreases p(HGNC:APP)
pmid:19519303	bp(GOBP:"maintenance of permeability of blood-brain barrier") decreases a(CHEBI:"amyloid-beta")
pmid:19519303	bp(GOBP:"maintenance of permeability of blood-brain barrier") association deg(a(CHEBI:"amyloid-beta"))
pmid:19519303	bp(GOBP:"maintenance of permeability of blood-brain barrier") association act(p(HGNC:INS))
pmid:19519303	bp(GOBP:"maintenance of permeability of blood-brain barrier") association p(HGNC:INS)
pmid:19519303	bp(GOBP:"maintenance of permeability of blood-brain barrier") association act(p(HGNC:IGF1))
pmid:15232608	bp(GOBP:"microglial cell activation involved in immune response") association a(MESH:D017628)
pmid:18715507	bp(GOBP:"microglial cell activation involved in immune response") association p(HGNC:IL1B)
pmid:18715507	bp(GOBP:"microglial cell activation involved in immune response") association p(HGNC:TNF)
pmid:22024597	bp(GOBP:"microglial cell activation involved in immune response") increases bp(GOBP:"chronic inflammatory response")
pmid:22024597	bp(GOBP:"microglial cell activation involved in immune response") increases path(MESHD:"Neurodegenerative Diseases")
pmid:18715507	bp(GOBP:"microglial cell activation involved in immune response") positiveCorrelation bp(GOBP:"inflammatory response")
pmid:18715507	bp(GOBP:"microglial cell activation involved in immune response") association p(HGNC:IL1A)
pmid:18715507	bp(GOBP:"microglial cell activation involved in immune response") increases bp(GOBP:"production of molecular mediator involved in inflammatory response")
pmid:18715507	bp(GOBP:"microglial cell activation involved in immune response") increases p(HGNC:DDX39B)
pmid:20205643	bp(GOBP:"microglial cell activation involved in immune response") decreases p(HGNC:APP, frag("672_713"))
pmid:19885299	bp(GOBP:"microglial cell activation") increases a(CHEBI:"amyloid-beta")
pmid:24369524	bp(GOBP:"microglial cell activation") association a(CHEBI:"amyloid-beta")
pmid:23197723	bp(GOBP:"microglial cell activation") decreases a(CHEBI:"amyloid-beta")
pmid:20100581	bp(GOBP:"microglial cell activation") association bp(GOBP:"apoptotic process")
pmid:15817521	bp(GOBP:"microglial cell activation") increases bp(GOBP:"chronic inflammatory response")
pmid:22277195	bp(GOBP:"microglial cell activation") increases path(MESHD:"Neurogenic Inflammation")
pmid:26836182	bp(GOBP:"microglial cell activation") positiveCorrelation bp(HBP:neuroinflammation)
pmid:20413894	bp(GOBP:"microglial cell activation") positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid: 26517285	bp(GOBP:"microglial cell activation") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:11755016	bp(GOBP:"microglial cell activation") increases bp(GOBP:"neuron death")
pmid:22890100	bp(GOBP:"microglial cell activation") positiveCorrelation p(HGNC:CHI3L1)
pmid:26836182	bp(GOBP:"microglial cell activation") increases p(HGNC:CHI3L1)
pmid:25681350	bp(GOBP:"microglial cell activation") association p(HGNC:TREM2)
pmid: 26517285	bp(GOBP:"microglial cell activation") association bp(GOBP:"immune response")
pmid:11556547	bp(GOBP:"microglial cell activation") association g(HGNC:ASS1)
pmid:11556547	bp(GOBP:"microglial cell activation") association g(HGNC:NOS2)
pmid:22367970	bp(GOBP:"mitochondrial fission") increases complex(a(CHEBI:"amyloid-beta"), p(HGNC:FIS1))
pmid:22453989	bp(GOBP:"negative regulation of calcium-mediated signaling") association a(CHEBI:"amyloid-beta")
pmid:22349563	bp(GOBP:"neuron cell-cell adhesion") association p(HGNC:APP)
pmid:22349563	bp(GOBP:"neuron cell-cell adhesion") association p(HGNC:APLP1)
pmid:22349563	bp(GOBP:"neuron cell-cell adhesion") association p(HGNC:APLP2)
pmid:20847424	bp(GOBP:"neuron cellular homeostasis") association a(CHEBI:"amyloid-beta")
pmid:22355794	bp(GOBP:"neuron development") association p(HGNC:APP)
pmid:22355794	bp(GOBP:"neuron development") association p(HGNC:APLP1)
pmid:23261660	bp(GOBP:"neuron development") positiveCorrelation p(HGNC:DKK1)
pmid:19515914	bp(GOBP:"neuron projection development") association p(HGNC:APP)
pmid:22349563	bp(GOBP:"neuron projection development") association p(HGNC:APP)
pmid:22349563	bp(GOBP:"neuron projection development") association p(HGNC:APLP1)
pmid:22349563	bp(GOBP:"neuron projection development") association p(HGNC:APLP2)
pmid:19515914	bp(GOBP:"neuron projection development") association p(FPLX:Integrins)
pmid:21903077	bp(GOBP:"neuronal signal transduction") association a(CHEBI:"nitric oxide")
pmid:22874667	bp(GOBP:"peptidyl-cysteine S-trans-nitrosylation") association p(HGNC:CDK5)
pmid:22874667	bp(GOBP:"peptidyl-cysteine S-trans-nitrosylation") association p(HGNC:CDK5)
pmid:22874667	bp(GOBP:"peptidyl-cysteine S-trans-nitrosylation") increases act(a(CHEBI:"amyloid-beta"))
pmid:20580937	bp(GOBP:"positive regulation of endocytosis") directlyIncreases a(CHEBI:"amyloid-beta")
pmid:15232608	bp(GOBP:"reactive oxygen species metabolic process") increases bp(GOBP:"neuron apoptotic process")
pmid:22496686	bp(GOBP:"reelin-mediated signaling pathway") association act(p(HGNC:RELN))
pmid:22512552	bp(GOBP:"regulation of blood pressure") association a(CHEBI:"nitric oxide")
pmid:7615568	bp(GOBP:"regulation of collagen fibril organization") association complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE))
pmid:1346802	bp(GOBP:"regulation of kainate selective glutamate receptor activity") association a(CHEBI:"amyloid-beta")
pmid:22355794	bp(GOBP:"regulation of long-term synaptic potentiation") association p(HGNC:APP)
pmid:22496686	bp(GOBP:"regulation of long-term synaptic potentiation") association p(HGNC:LRP8)
pmid:22349563	bp(GOBP:"regulation of neuron migration") association p(HGNC:APP)
pmid:22349563	bp(GOBP:"regulation of neuron migration") association p(HGNC:APLP1)
pmid:22349563	bp(GOBP:"regulation of neuron migration") association p(HGNC:APLP2)
pmid:19515914	bp(GOBP:"regulation of neuron migration") association p(FPLX:Integrins)
pmid:19515914	bp(GOBP:"regulation of neuron migration") association complex(p(HGNC:LRP8), p(HGNC:RELN))
pmid:19515914	bp(GOBP:"regulation of neuron migration") association complex(p(HGNC:RELN), p(HGNC:VLDLR))
pmid:19909279	bp(GOBP:"regulation of neuronal synaptic plasticity") association p(HGNC:EGR1)
pmid:19519303	bp(GOBP:"regulation of phosphatidylinositol 3-kinase activity") association a(CHEBI:"amyloid-beta")
pmid:20847424	bp(GOBP:"regulation of synaptic activity") increases bp(GOBP:endocytosis)
pmid:20847424	bp(GOBP:"regulation of synaptic activity") increases p(HGNC:APP, frag("672_713"))
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRA1)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRA2)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRA3)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRA4)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRA5)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRA6)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRB1)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRB2)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRB3)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRG1)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRG2)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRG3)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRD)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRE)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRP)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GABRQ)
pmid:19909279	bp(GOBP:"regulation of synaptic plasticity") association p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")
pmid: 22646481	bp(GOBP:"regulation of synaptic plasticity") association act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits"))
pmid:20035739	bp(GOBP:"regulation of synaptic plasticity") association p(HGNC:GCG)
pmid: 21543606	bp(GOBP:"regulation of synaptic plasticity") association bp(GOBP:"axonal defasciculation")
pmid: 21543606	bp(GOBP:"regulation of synaptic plasticity") association bp(GOBP:myelination)
pmid:18675468	bp(GOBP:"regulation of transcription, DNA-templated") association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22399757	bp(GOBP:"regulation of ubiquitin-specific protease activity") association path(MESHD:"Alzheimer Disease")
pmid:22523685	bp(GOBP:"respiratory chain complex IV assembly") decreases a(CHEBI:radical)
pmid:22115781	bp(GOBP:"response to endoplasmic reticulum stress") increases p(HGNC:PSEN1)
pmid:22115781	bp(GOBP:"response to endoplasmic reticulum stress") increases act(p(HGNC:ATF4))
pmid:22115781	bp(GOBP:"response to endoplasmic reticulum stress") increases act(complex(SCOMP:"gamma Secretase Complex"), ma(pep))
pmid:22115781	bp(GOBP:"response to endoplasmic reticulum stress") increases path(MESHD:Obesity)
pmid:22115781	bp(GOBP:"response to endoplasmic reticulum stress") increases path(MESHD:"Diabetes Mellitus, Type 2")
pmid:22249458	bp(GOBP:"response to oxidative stress") increases p(HGNC:BACE1)
pmid:22249458	bp(GOBP:"response to oxidative stress") increases act(p(HGNC:MAPK3))
pmid:21985244	bp(GOBP:"response to oxidative stress") increases p(HGNC:SNCA)
pmid:21985244	bp(GOBP:"response to oxidative stress") increases p(HGNC:MAPT, pmod(Ph))
pmid:22382662	bp(GOBP:"response to stress") increases a(CHEBI:"amyloid-beta")
pmid:22222439	bp(GOBP:"response to stress") increases p(HGNC:MAPT, pmod(Ph))
pmid:22222439	bp(GOBP:"response to stress") increases act(p(HGNC:CRH))
pmid:12084708	bp(GOBP:"signal transduction") association complex(p(HGNC:APP), p(HGNC:SHC1))
pmid:12084708	bp(GOBP:"signal transduction") association complex(p(HGNC:APP), p(HGNC:GRB2))
pmid:18675468	bp(GOBP:"sodium ion homeostasis") negativeCorrelation bp(GOBP:"membrane lipid catabolic process")
pmid:18509662	bp(GOBP:"water homeostasis") association p(HGNC:AQP1)
pmid:20651816	bp(GOBP:endocytosis) increases complex(complex(SCOMP:"gamma Secretase Complex"), p(HGNC:APP), p(HGNC:BACE1))
pmid:20847424	bp(GOBP:endocytosis) increases tloc(p(HGNC:APP), fromLoc(MESHCS:"Cell Membrane"), toLoc(MESHCS:Endosomes))
pmid:20127045	bp(GOBP:endocytosis) association p(HGNC:RAB5A)
pmid:20127045	bp(GOBP:endocytosis) association path(MESHD:"Alzheimer Disease")
pmid:22349563	bp(GOBP:neurogenesis) association p(HGNC:APP)
pmid:22349563	bp(GOBP:neurogenesis) association p(HGNC:APLP1)
pmid:22349563	bp(GOBP:neurogenesis) association p(HGNC:APLP2)
pmid:10366748	bp(GOBP:neurogenesis) association p(HGNC:NOTCH1)
pmid:21352095	bp(HBP:amyloidogenesis) association a(CHEBI:cholesterol)
pmid:22223749	bp(HBP:amyloidogenesis) association path(MESHD:"Alzheimer Disease")
pmid:12607822	bp(MESHPP:"Lipid Peroxidation") increases a(CHEBI:"4-hydroxynon-2-enal")
pmid:20385830	bp(MESHPP:"Long-Term Potentiation") association bp(GOBP:"learning or memory")
pmid:19519303	bp(MESHPP:"Long-Term Potentiation") association bp(GOBP:"ERK1 and ERK2 cascade")
pmid:19383491	bp(MESHPP:"Long-Term Potentiation") association p(HGNC:INS)
pmid:19383491	bp(MESHPP:"Long-Term Potentiation") increases bp(GOBP:"calcium ion import")
pmid:20042680	bp(MESHPP:"Long-Term Potentiation") positiveCorrelation a(CHEBI:memantine)
pmid:19885299	bp(MESHPP:"Oxidative Stress") positiveCorrelation g(HGNC:APP)
pmid:19885299	bp(MESHPP:"Oxidative Stress") increases g(HGNC:APP)
pmid:19885299	bp(MESHPP:"Oxidative Stress") positiveCorrelation deg(p(HGNC:APP))
pmid:19885299	bp(MESHPP:"Oxidative Stress") increases rxn(reactants(p(HGNC:APP)), products(p(HGNC:APP, frag("672_713"))))
pmid:12548636	bp(MESHPP:"Oxidative Stress") increases bp(GOBP:"apoptotic process")
pmid:12548636	bp(MESHPP:"Oxidative Stress") increases p(MGI:Hspd1, pmod(GO:"GO:0018158"))
pmid:12548636	bp(MESHPP:"Oxidative Stress") increases p(MGI:Vim, pmod(GO:"GO:0018158"))
pmid:24262633	bp(MESHPP:"Oxidative Stress") association act(p(HGNC:NFE2L2))
pmid:20064547	bp(MESHPP:"Oxidative Stress") association p(HGNC:NFE2L2)
pmid:24262633	bp(MESHPP:"Oxidative Stress") increases tloc(p(HGNC:NFE2L2), fromLoc(MESHCS:Cytoplasm), toLoc(MESHCS:"Cell Nucleus"))
pmid:20064547	bp(MESHPP:"Oxidative Stress") association p(HGNC:KEAP1)
pmid:11226677	bp(MESHPP:"Oxidative Stress") increases p(HGNC:BCL2L1)
pmid:19885299	bp(MESHPP:"Oxidative Stress") positiveCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:17316694	bp(MESHPP:"Oxidative Stress") association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:19885299	bp(MESHPP:"Oxidative Stress") negativeCorrelation bp(GOBP:"insulin receptor signaling pathway")
pmid:19885299	bp(MESHPP:"Oxidative Stress") negativeCorrelation bp(GOBP:"insulin-like growth factor receptor signaling pathway")
pmid:14970312	bp(MESHPP:"Oxidative Stress") association path(MESHD:"Alzheimer Disease")
pmid:17316694	bp(MESHPP:"Oxidative Stress") association path(MESHD:"Alzheimer Disease")
pmid:23653222	bp(MESHPP:"Oxidative Stress") association path(MESHD:"Alzheimer Disease")
pmid:14970312	bp(MESHPP:"Oxidative Stress") association bp(GOBP:"regulation of lipid metabolic process")
pmid:14970312	bp(MESHPP:"Oxidative Stress") increases a(CHEBI:ceramide)
pmid:15255951	bp(MESHPP:"Oxidative Stress") association path(MESHD:"Neurodegenerative Diseases")
pmid:23653222	bp(MESHPP:"Oxidative Stress") association path(MESHD:"Neurodegenerative Diseases")
pmid:17316167	bp(MESHPP:"Oxidative Stress") association path(MESHD:"Neurodegenerative Diseases")
pmid:15255951	bp(MESHPP:"Oxidative Stress") association p(HGNC:MPO)
pmid:20847424	bp(MESHPP:"Oxidative Stress") association a(MESH:D008928)
pmid:20847424	bp(MESHPP:"Oxidative Stress") association a(CHEBI:"amyloid-beta polypeptide 42")
pmid:22956607	bp(MESHPP:"Oxidative Stress") positiveCorrelation path(MESHD:"Fuchs' Endothelial Dystrophy")
pmid:17316167	bp(MESHPP:"Oxidative Stress") association p(HGNC:SPP1)
pmid:19076431	bp(MESHPP:"Oxidative Stress") increases bp(GOBP:"cell death")
pmid:21893081	bp(MESHPP:"Oxidative Stress") decreases bp(GOBP:memory)
pmid:18718604	bp(MESHPP:"Oxidative Stress") association p(HGNC:PLA2G4A)
pmid:7695621	complex(GOCC:"neurofibrillary tangle") association p(HGNC:APOE)
pmid:21389115	complex(GOCC:"neurofibrillary tangle") association act(p(HGNC:CDK5), ma(kin))
pmid:21156028	complex(GOCC:"neurofibrillary tangle") increases bp(GOBP:"neuron death")
pmid:23627755	complex(GOCC:"neurofibrillary tangle") positiveCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:23557940	complex(GOCC:"neurofibrillary tangle") negativeCorrelation act(p(HGNC:IGF1))
pmid:23557940	complex(GOCC:"neurofibrillary tangle") positiveCorrelation bp(MESHPP:"Insulin Resistance")
pmid:22718756	complex(GOCC:"neurofibrillary tangle") positiveCorrelation bp(GOBP:"neurofibrillary tangle assembly")
pmid:23362255	complex(GOCC:"neurofibrillary tangle") increases path(MESHD:"Alzheimer Disease")
pmid:16504486	complex(GOCC:"neurofibrillary tangle") association path(MESHD:"Alzheimer Disease")
pmid:16504486	complex(GOCC:"neurofibrillary tangle") association p(HGNC:MAPT, pmod(Ph))
pmid:8129042	complex(GOCC:"neurofibrillary tangle") negativeCorrelation r(HGNC:MAPK1)
pmid:7695621	complex(GOCC:"neurofibrillary tangle") association complex(p(HGNC:APOE), p(HGNC:MAPT))
pmid:18494933	complex(GOCC:"neurofibrillary tangle") increases bp(GOBP:"inflammatory response")
pmid:22523685	complex(GOCC:"respiratory chain complex IV") negativeCorrelation p(HGNC:APP, frag("49_*"))
pmid:22523685	complex(GOCC:"respiratory chain complex IV") negativeCorrelation p(HGNC:APP, frag("50_*"))
pmid:22523685	complex(GOCC:"respiratory chain complex IV") isA p(ECCODE:"1.9.3.1")
pmid:18782350	act(complex(SCOMP:"Calcineurin Complex")) decreases p(HGNC:BAD, pmod(Ph))
pmid:18782350	act(complex(SCOMP:"Calcineurin Complex")) increases bp(GOBP:"cell death")
pmid:18782350	act(complex(SCOMP:"Calcineurin Complex")) decreases p(SFAM:"CREB Family", pmod(Ph))
pmid:22434822	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:22702962	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:15232608	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:22434822	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) directlyIncreases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:21785276	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) directlyIncreases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:22434822	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:22710916	act(complex(SCOMP:"gamma Secretase Complex"), ma(cat)) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:16696577	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases p(HGNC:APP, frag("672_713"))
pmid:23296004	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) association complex(p(HGNC:APH1A), p(HGNC:ARRB2))
pmid:23296004	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19276086	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:22115781	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:18650430	act(complex(SCOMP:"gamma Secretase Complex")) increases deg(p(HGNC:APP))
pmid:22613765	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta"), p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")))
pmid:22434822	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) directlyIncreases rxn(reactants(p(MGI:App)), products(a(CHEBI:"amyloid-beta")))
pmid:22496686	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases deg(p(HGNC:LRP1))
pmid:22496686	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases deg(p(HGNC:LRP1))
pmid:22496686	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases deg(p(HGNC:LRP2))
pmid:22496686	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases deg(p(HGNC:LRP3))
pmid:22496686	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases deg(p(HGNC:LRP4))
pmid:22496686	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases deg(p(HGNC:LRP6))
pmid:22496686	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases deg(p(HGNC:LRP8))
pmid:22496686	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases deg(p(HGNC:LRP8))
pmid:22496686	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases deg(p(HGNC:LRP10))
pmid:22496686	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases deg(p(HGNC:LRP11))
pmid:22496686	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases deg(p(HGNC:LRP11))
pmid:22496686	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases act(p(SFAM:"NOTCH Family"))
pmid:22461631	act(complex(SCOMP:"gamma Secretase Complex")) increases p(HGNC:APP, frag("?"))
pmid:22461631	act(complex(SCOMP:"gamma Secretase Complex")) increases p(SFAM:"NOTCH Family", frag("?"))
pmid:12639958	complex(SCOMP:"gamma Secretase Complex") increases bp(GOBP:"Notch signaling pathway")
pmid:17599166	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases bp(GOBP:"Notch signaling pathway")
pmid:20883690	act(complex(SCOMP:"gamma Secretase Complex"), ma(pep)) increases rxn(reactants(p(FPLX:Notch)), products(a(HBP:"Notch intracellular domain")))
pmid:15160835	complex(a(CHEBI:"amyloid-beta"), a(CHEBI:lipid)) increases bp(GOBP:"amyloid fibril formation")
pmid:19519303	complex(a(CHEBI:"amyloid-beta"), p(HGNC:A2M), p(HGNC:LRP1)) association deg(a(CHEBI:"amyloid-beta"))
pmid:9489740	p(HGNC:A2M) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:9489740	p(HGNC:A2M) increases bp(GOBP:"amyloid fibril formation")
pmid:10797543	deg(p(HGNC:A2M)) association p(HGNC:LRP1)
pmid:14678766	p(HGNC:A2M) association bp(GO:"GO:0097242")
pmid:14678766	p(HGNC:A2M) decreases p(HGNC:APP, frag("672_713"))
pmid:14678766	p(HGNC:A2M) decreases a(CHEBI:"amyloid-beta")
pmid:23167255	p(HGNC:LRP1) increases path(MESHD:"Alzheimer Disease")
pmid:21676498	p(HGNC:LRP1) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:17012232	p(HGNC:LRP1) increases complex(p(HGNC:APP, frag("672_713")), p(HGNC:LRP1))
pmid:18288927	act(p(HGNC:LRP1), ma(tport)) directlyIncreases tloc(complex(p(HGNC:APP, frag("672_713")), p(HGNC:LRP1)), fromLoc(MESHCS:"Cell Membrane"), toLoc(MESHCS:Endosomes))
pmid:22429478	p(HGNC:LRP1) decreases complex(p(HGNC:APBB1), p(HGNC:APP), p(HGNC:LRP8))
pmid:21676498	p(HGNC:LRP1) association p(HGNC:APOE)
pmid:10797543	p(HGNC:LRP1) association deg(p(HGNC:APOE))
pmid:1632469	p(HGNC:LRP1) association bp(GOBP:"regulation of peptidase activity")
pmid:1632469	p(HGNC:LRP1) association act(a(MESHC:Cytokines))
pmid:1632469	p(HGNC:LRP1) association bp(GOBP:"cholesterol metabolic process")
pmid:10797543	p(HGNC:LRP1) association deg(p(HGNC:APP))
pmid:15772078	p(HGNC:LRP1) association p(HGNC:APP)
pmid:10797543	p(HGNC:LRP1) association deg(p(HGNC:A2M))
pmid:10806097	act(p(HGNC:LRP1), ma(tport)) increases tloc(p(HGNC:A2M))
pmid:17012232	p(HGNC:LRP1) increases complex(p(HGNC:APOE), p(HGNC:LRP1))
pmid:15772078	p(HGNC:LRP1) association a(CHEBI:"amyloid-beta")
pmid:15772078	p(HGNC:LRP1) regulates bp(GO:"GO:0097242")
pmid:18288927	act(p(HGNC:LRP1), ma(tport)) increases bp(GO:"GO:0097242")
pmid:17694066	p(HGNC:LRP1) association deg(p(HGNC:APP, frag("672_713")))
pmid:18288927	act(p(HGNC:LRP1), ma(tport)) decreases p(HGNC:APP, frag("672_713"))
pmid:10806097	p(HGNC:LRP1) increases complex(p(HGNC:APP), p(HGNC:LRP1))
pmid:10806097	act(p(HGNC:LRP1), ma(tport)) increases tloc(p(HGNC:SERPINE1))
pmid:17424907	complex(a(CHEBI:"amyloid-beta"), p(HGNC:ADH1B)) decreases bp(GOBP:"mitochondrial protein catabolic process")
pmid:17424907	complex(a(CHEBI:"amyloid-beta"), p(HGNC:ADH1B)) increases a(CHEBI:"reactive oxygen species")
pmid:11520119	complex(a(CHEBI:"amyloid-beta"), p(HGNC:AGER)) increases bp(GOBP:"positive regulation of cellular process")
pmid:9144231	complex(a(CHEBI:"amyloid-beta"), p(HGNC:AGER)) increases p(HGNC:CSF1)
pmid:19332646	p(HGNC:AGER) increases act(p(HGNC:NFATC1))
pmid:19332646	p(HGNC:AGER) increases p(HGNC:BACE1)
pmid:19332646	p(HGNC:AGER) association act(p(HGNC:BACE1), ma(pep))
pmid:19332646	p(HGNC:AGER) increases a(CHEBI:"amyloid-beta")
pmid:18657529	p(HGNC:AGER) increases path(MESHD:"Alzheimer Disease")
pmid:15975028	p(HGNC:AGER) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:18480271	p(HGNC:AGER) increases bp(GOBP:"cell death")
pmid:19388207	act(p(HGNC:AGER)) increases bp(GOBP:"inflammatory response")
pmid:18480271	p(HGNC:AGER) increases bp(MESHPP:"Oxidative Stress")
pmid:10673326	complex(a(CHEBI:"amyloid-beta"), p(HGNC:AGRN)) increases bp(GOBP:"amyloid fibril formation")
pmid:9265639	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE)) association a(CHEBI:"amyloid-beta")
pmid:11305869	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE)) increases complex(GOCC:"neurofibrillary tangle")
pmid:11816788	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE)) association path(MESHD:"Alzheimer Disease")
pmid:16207708	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE)) association path(MESHD:"Alzheimer Disease")
pmid:8040342	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE)) association path(MESHD:"Alzheimer Disease")
pmid:9265639	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE)) association path(MESHD:"Alzheimer Disease")
pmid:11840304	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE)) association path(MESHD:"Alzheimer Disease")
pmid:15181252	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE)) association path(MESHD:"Alzheimer Disease")
pmid:8631862	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE)) association path(MESHD:"Alzheimer Disease")
pmid:8679539	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE)) association path(MESHD:"Alzheimer Disease")
pmid:7615568	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE)) association bp(GOBP:"regulation of collagen fibril organization")
pmid:18297066	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE)) association bp(GOBP:"amyloid fibril formation")
pmid:7639323	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE)) association bp(GOBP:"amyloid fibril formation")
pmid:21239853	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE)) increases bp(PTS:"amyloid pathway")
pmid:7695621	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE)) association a(ADO:"senile_plaque")
pmid:21769591	p(HGNC:APOE) association path(MESHD:"Alzheimer Disease")
pmid:22496686	p(HGNC:APOE) association path(MESHD:"Alzheimer Disease")
pmid:11070505	p(HGNC:APOE) association path(MESHD:"Alzheimer Disease")
pmid:12015813	p(HGNC:APOE) association path(MESHD:"Alzheimer Disease")
pmid:14501024	p(HGNC:APOE) association path(MESHD:"Alzheimer Disease")
pmid:7695621	p(HGNC:APOE) association path(MESHD:"Alzheimer Disease")
pmid:22496686	p(HGNC:APOE) association a(CHEBI:"amyloid-beta")
pmid:20675880	p(HGNC:APOE) increases a(CHEBI:"amyloid-beta")
pmid:11070505	p(HGNC:APOE) increases a(CHEBI:"amyloid-beta")
pmid:11305869	p(HGNC:APOE) increases a(CHEBI:"amyloid-beta")
pmid:12590160	p(HGNC:APOE) increases a(CHEBI:"amyloid-beta")
pmid:16195918	p(HGNC:APOE) association a(CHEBI:"amyloid-beta")
pmid:18297066	p(HGNC:APOE) decreases a(CHEBI:"amyloid-beta")
pmid:22323736	p(HGNC:APOE) decreases deg(a(CHEBI:"amyloid-beta"))
pmid:17495608	p(HGNC:APOE) increases p(HGNC:APP, frag("672_713"))
pmid:21676498	p(HGNC:APOE) association p(HGNC:APP, frag("672_713"))
pmid:18549781	p(HGNC:APOE) association p(HGNC:APP, frag("672_713"))
pmid:18549781	p(HGNC:APOE) decreases p(HGNC:APP, frag("672_713"))
pmid:10852539	p(HGNC:APOE) increases a(ADO:"senile_plaque")
pmid:7695621	p(HGNC:APOE) association a(ADO:"senile_plaque")
pmid:18297066	p(HGNC:APOE) positiveCorrelation act(a(MESH:D009474))
pmid:20052565	p(HGNC:APOE) decreases a(CHEBI:"galactosylceramide sulfate")
pmid:7695621	p(HGNC:APOE) association complex(GOCC:"neurofibrillary tangle")
pmid:11553277	p(HGNC:APOE) increases bp(PTS:"amyloidogenic pathway")
pmid:18415033	p(HGNC:APOE) association p(HGNC:APP)
pmid:19058878	p(HGNC:APOE) decreases p(HGNC:APP)
pmid:19058878	p(HGNC:APOE) decreases p(HGNC:APP, pmod(Ph))
pmid:19058878	p(HGNC:APOE) decreases complex(p(HGNC:APP), p(HGNC:SRC))
pmid:19035514	p(HGNC:APOE) increases act(p(HGNC:CASR))
pmid:22496686	p(HGNC:APOE) association composite(p(HGNC:LRP1), p(HGNC:LRP10), p(HGNC:LRP11), p(HGNC:LRP2), p(HGNC:LRP3), p(HGNC:LRP4), p(HGNC:LRP5), p(HGNC:LRP6), p(HGNC:LRP8))
pmid:22496686	p(HGNC:APOE) association p(HGNC:VLDLR)
pmid:22496686	p(HGNC:APOE) association p(HGNC:HDLBP)
pmid:18675468	p(HGNC:APOE) decreases act(complex(p(HGNC:LRP8), p(HGNC:RELN)))
pmid:21676498	p(HGNC:APOE) association p(HGNC:LRP1)
pmid:10797543	deg(p(HGNC:APOE)) association p(HGNC:LRP1)
pmid:21676498	p(HGNC:APOE) association bp(GOBP:"cholesterol homeostasis")
pmid:12117549	p(HGNC:APOE) increases p(HGNC:LRP1B)
pmid:15181248	p(HGNC:APOE) decreases a(MESHC:"Nitric Oxide Synthase")
pmid:16054114	p(HGNC:APOE) increases a(CHEBI:"nitric oxide")
pmid:20847424	p(HGNC:APOE) association bp(GOBP:"cholesterol transport")
pmid:18549781	p(HGNC:APOE) increases complex(p(HGNC:APOE), p(HGNC:APP, frag("672_713")))
pmid:8823200	p(HGNC:APOE) decreases bp(GOBP:"amyloid fibril formation")
pmid:9512010	p(HGNC:APOE) association p(HGNC:MAPT, pmod(Ph))
pmid:19519303	complex(a(CHEBI:"amyloid-beta"), p(HGNC:APOE), p(HGNC:LRP1)) association deg(a(CHEBI:"amyloid-beta"))
pmid:22500019	complex(a(CHEBI:"amyloid-beta"), p(HGNC:CALCR)) increases act(p(HGNC:RAMP3))
pmid:22500019	p(HGNC:CALCR) association p(HGNC:RAMP1)
pmid:22500019	p(HGNC:CALCR) association p(HGNC:RAMP2)
pmid:22500019	p(HGNC:CALCR) association p(HGNC:RAMP3)
pmid:19651157	complex(a(CHEBI:"amyloid-beta"), p(HGNC:CLU)) decreases bp(GOBP:"amyloid fibril formation")
pmid:22232000	act(p(HGNC:CLU), ma(tport)) increases tloc(a(CHEBI:"amyloid-beta"), fromLoc(MESH:D001921), toLoc(MESH:D001769))
pmid:23164821	p(HGNC:CLU) positiveCorrelation p(HGNC:APP, frag("672_713"))
pmid: 21543606	p(HGNC:CLU) association p(HGNC:APP, frag("672_713"))
pmid:8892344	p(HGNC:CLU) decreases p(HGNC:APP, frag("672_713"))
pmid:19996109	act(p(HGNC:CLU), ma(chap)) decreases p(HGNC:APP, frag("672_713"))
pmid:23164821	p(HGNC:CLU) positiveCorrelation p(HGNC:DKK1)
pmid:23164821	p(HGNC:CLU) decreases p(HGNC:DKK1)
pmid:23164821	p(HGNC:CLU, loc(MESHCS:Cytosol)) increases bp(PTS:"p53 signaling pathway")
pmid:23164821	tloc(p(HGNC:CLU), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space")) increases bp(PTS:"p53 signaling pathway")
pmid:23164821	p(HGNC:CLU, loc(MESHCS:Cytosol)) increases bp(PTS:"p53 signaling pathway")
pmid:23164821	tloc(p(HGNC:CLU), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space")) increases bp(PTS:"p53 signaling pathway")
pmid: 21543606	p(HGNC:CLU) association g(DBSNP:rs11136000)
pmid: 21543606	p(HGNC:CLU) decreases a(NIFT:"Fractional anisotropy")
pmid:8892344	act(p(HGNC:CLU)) increases bp(GOBP:"response to misfolded protein")
pmid:19996109	act(p(HGNC:CLU), ma(chap)) directlyIncreases bp(GOBP:"receptor-mediated endocytosis")
pmid:22523685	complex(a(CHEBI:"amyloid-beta"), p(HGNC:HSD17B10)) decreases bp(GOBP:"mitochondrion organization")
pmid:10371197	p(HGNC:HSD17B10) association bp(GOBP:"apoptotic process")
pmid:23713771	complex(a(CHEBI:"amyloid-beta"), p(HGNC:IAPP)) association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:23713771	complex(a(CHEBI:"amyloid-beta"), p(HGNC:IAPP)) association path(MESHD:"Alzheimer Disease")
pmid:22500019	p(HGNC:IAPP) increases bp(GOBP:"cell death")
pmid:22321797	tloc(p(HGNC:IAPP), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space")) association deg(a(MESH:D050417))
pmid:15094078	complex(a(CHEBI:"amyloid-beta"), p(HGNC:INSR)) decreases act(p(HGNC:INSR))
pmid:15094078	act(p(HGNC:INSR)) negativeCorrelation a(CHEBI:"amyloid-beta")
pmid:19885299	act(p(HGNC:INSR)) positiveCorrelation bp(GOBP:"insulin receptor signaling pathway")
pmid:19885299	act(p(HGNC:INSR)) increases p(HGNC:IRS1, pmod(Ph))
pmid:19885299	act(p(HGNC:INSR)) increases p(HGNC:IRS2, pmod(Ph))
pmid:19885299	act(p(HGNC:INSR)) increases p(HGNC:IRS4, pmod(Ph))
pmid:19885299	p(HGNC:INSR) negativeCorrelation bp(MESHPP:"Insulin Resistance")
pmid:19885299	act(p(HGNC:INSR)) negativeCorrelation bp(MESHPP:"Insulin Resistance")
pmid:21916834	p(HGNC:INSR) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19188609	tloc(p(HGNC:INSR), fromLoc(GOCC:intracellular), toLoc(GOCC:"cell surface")) positiveCorrelation act(p(HGNC:INS))
pmid:19188609	tloc(p(HGNC:INSR), fromLoc(GOCC:intracellular), toLoc(GOCC:"cell surface")) negativeCorrelation complex(p(HGNC:ADD3), p(HGNC:INSR))
pmid:19188609	p(HGNC:INSR) association bp(GOBP:"regulation of protein tyrosine kinase activity")
pmid:19188609	p(HGNC:INSR) negativeCorrelation act(p(HGNC:ADD3))
pmid:21289241	p(HGNC:INSR) negativeCorrelation path(MESHD:"Diabetes, Gestational")
pmid:20847424	act(p(HGNC:INSR)) increases bp(GOBP:"positive regulation of synaptic plasticity")
pmid:19519303	complex(a(CHEBI:"amyloid-beta"), p(HGNC:LRP1)) association deg(a(CHEBI:"amyloid-beta"))
pmid:22236693	p(HGNC:NGFR) increases complex(a(CHEBI:"amyloid-beta"), p(HGNC:NGFR))
pmid:19334058	p(HGNC:NGFR) decreases act(p(HGNC:APBB1))
pmid:17385278	p(HGNC:NGFR) association a(CHEBI:"amyloid-beta")
pmid:17385278	act(p(HGNC:NGFR)) increases p(HGNC:NOS2)
pmid:24293250	complex(a(CHEBI:"amyloid-beta"), p(HGNC:NOS1)) increases bp(GOBP:"amyloid fibril formation")
pmid:24293250	p(HGNC:NOS1) association a(CHEBI:nanoparticle)
pmid:20100581	p(HGNC:NOS1) association p(HGNC:IFNG)
pmid:18806802	complex(a(CHEBI:"amyloid-beta"), p(HGNC:PPIF)) increases bp(MESHPP:"Stress, Physiological")
pmid:21393248	complex(a(CHEBI:"amyloid-beta"), p(HGNC:PRNP)) association path(MESHD:"Alzheimer Disease")
pmid:22500019	complex(a(CHEBI:"amyloid-beta"), p(HGNC:RAMP1)) increases act(a(CHEBI:"amyloid-beta"))
pmid:22500019	p(HGNC:RAMP1) association p(HGNC:CALCR)
pmid:22500019	complex(a(CHEBI:"amyloid-beta"), p(HGNC:RAMP2)) increases act(a(CHEBI:"amyloid-beta"))
pmid:22500019	p(HGNC:RAMP2) association p(HGNC:CALCR)
pmid:22500019	complex(a(CHEBI:"amyloid-beta"), p(HGNC:RAMP3)) increases act(a(CHEBI:"amyloid-beta"))
pmid:22500019	p(HGNC:RAMP3) association p(HGNC:CALCR)
pmid:22500019	act(p(HGNC:RAMP3)) increases bp(GOBP:"cell death")
pmid:20651816	complex(a(CHEBI:"calcium(2+)"), p(HGNC:MARCKS)) increases tloc(p(HGNC:MARCKS), fromLoc(MESHCS:"Cell Membrane"), toLoc(MESHCS:Cytoplasm))
pmid:16696577	p(HGNC:APP, frag("672_711")) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:11226677	p(HGNC:APP, frag("672_711")) increases r(HGNC:BCL2L1)
pmid:11226677	p(HGNC:APP, frag("672_711")) increases p(HGNC:BCL2L1)
pmid:21193044	p(HGNC:APP, frag("672_711")) decreases bp(MESHPP:"Cerebrovascular Circulation")
pmid:19035353	p(HGNC:APP, frag("672_711")) association p(HGNC:NECAB3)
pmid:17507561	p(HGNC:APP, frag("672_711")) increases act(p(HGNC:NFKB1))
pmid:17507561	p(HGNC:APP, frag("672_711")) increases act(p(HGNC:MAPK8))
pmid:17507561	p(HGNC:APP, frag("672_711")) increases p(HGNC:NOS2)
pmid:17507561	p(HGNC:APP, frag("672_711")) increases p(HGNC:TNF)
pmid:17385278	p(HGNC:APP, frag("672_711")) increases act(p(HGNC:NGFR))
pmid:26783546	p(HGNC:APP, frag("672_711")) positiveCorrelation p(HGNC:CHI3L1)
pmid:26783546	p(HGNC:APP, frag("672_711")) positiveCorrelation p(HGNC:NRGN)
pmid:20139999	p(HGNC:APP, frag("672_711")) negativeCorrelation p(HGNC:ATXN1)
pmid:18675468	p(HGNC:APP, frag("672_711")) directlyDecreases bp(GOBP:"calcium ion import")
pmid:18675468	p(HGNC:APP, frag("672_711")) directlyDecreases bp(GOBP:"calcium ion homeostasis")
pmid:22844264	complex(a(CHEBI:"copper(2+)"), p(HGNC:APP, frag("672_713"))) association path(MESHD:"Alzheimer Disease")
pmid:14530380	complex(a(CHEBI:"heparan sulfate"), p(HGNC:BACE1)) association a(CHEBI:"amyloid-beta")
pmid:22434822	act(p(HGNC:BACE1), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:22702962	act(p(HGNC:BACE1), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:15232608	act(p(HGNC:BACE1), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:22047170	act(p(HGNC:BACE1), ma(pep)) directlyIncreases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:20385830	act(p(HGNC:BACE1), ma(cat)) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:19237574	act(p(HGNC:BACE1), ma(pep)) directlyIncreases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:22434822	act(p(HGNC:BACE1), ma(pep)) directlyIncreases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:21785276	act(p(HGNC:BACE1), ma(pep)) directlyIncreases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:21785276	act(p(HGNC:BACE1), ma(pep)) directlyIncreases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:21329555	act(p(HGNC:BACE1), ma(pep)) directlyIncreases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:19765582	act(p(HGNC:BACE1), ma(pep)) directlyIncreases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:22249458	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:22267734	p(HGNC:BACE1) increases a(CHEBI:"amyloid-beta")
pmid:17428983	tloc(p(HGNC:BACE1), fromLoc(MESHCS:"Cell Surface Extensions"), toLoc(MESHCS:Endosomes)) increases a(CHEBI:"amyloid-beta")
pmid:22166376	p(HGNC:BACE1) increases a(CHEBI:"amyloid-beta")
pmid:22178568	p(HGNC:BACE1) increases a(CHEBI:"amyloid-beta")
pmid:22249458	p(HGNC:BACE1) increases a(CHEBI:"amyloid-beta")
pmid:10500121	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:10956649	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:15218540	act(p(HGNC:BACE1), ma(pep)) increases tloc(a(CHEBI:"amyloid-beta"), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:15452128	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:15465276	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:15663471	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:15824102	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:16027115	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:16290302	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:16888322	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17205046	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17255335	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17360493	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17536186	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17573534	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17586478	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17611486	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17908048	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:18162398	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:18308724	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:18410513	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:18570439	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:18675254	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19196431	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19199126	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19330459	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19405102	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19462468	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19464074	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19669607	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19698775	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19729516	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19885829	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19887909	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20067575	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20089133	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20157255	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20171164	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20303415	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20409323	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20451519	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20685197	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20727383	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:21034535	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:21433051	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:9623986	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:9775403	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:10096041	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:10591213	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:10677483	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:11114266	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:11737828	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:11839594	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:11953458	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:12112088	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:12470797	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:12473667	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:12515826	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:12603825	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:14501002	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:14530380	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:14557249	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:14600149	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:14622952	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:14715132	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:14973371	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:15057522	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:15080893	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:15211591	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:15314262	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:15467394	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:15473697	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:15642747	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:15857888	act(p(HGNC:BACE1), ma(pep)) increases act(a(CHEBI:"amyloid-beta"))
pmid:16306400	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:16716081	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:16768248	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:16979658	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17121991	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17156133	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17223266	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17409228	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17500040	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17541560	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17553422	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17616527	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:18068983	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:18263584	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:18295609	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:18479216	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:18979625	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19332646	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19366692	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19442147	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:19828790	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20092570	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20097758	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20139999	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20371462	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20374499	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20592218	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20704561	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20720123	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20726888	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20886088	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:21059265	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:21245145	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:7876155	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:8621560	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:9152995	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20731541	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:15466887	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:12473667	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17098871	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:15189355	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:11724784	act(p(HGNC:BACE1), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:BACE1) increases a(CHEBI:"amyloid-beta")
pmid:19245828	p(HGNC:BACE1) increases a(CHEBI:"amyloid-beta")
pmid:15452128	act(p(HGNC:BACE1), ma(pep)) association path(MESHD:"Alzheimer Disease")
pmid:15080893	p(HGNC:BACE1) association path(MESHD:"Alzheimer Disease")
pmid:15467394	act(p(HGNC:BACE1), ma(pep)) increases path(MESHD:"Alzheimer Disease")
pmid:22178568	p(HGNC:BACE1) positiveCorrelation p(HGNC:BACE1)
pmid:18650430	act(p(HGNC:BACE1), ma(pep)) increases deg(p(HGNC:APP))
pmid:15452128	act(p(HGNC:BACE1), ma(pep)) increases deg(p(HGNC:APP))
pmid:15465276	act(p(HGNC:BACE1), ma(pep)) increases deg(p(HGNC:APP))
pmid:15663471	act(p(HGNC:BACE1), ma(pep)) increases deg(p(HGNC:APP))
pmid:15824102	act(p(HGNC:BACE1), ma(pep)) directlyIncreases deg(p(HGNC:APP))
pmid:16027115	act(p(HGNC:BACE1), ma(pep)) directlyIncreases deg(p(HGNC:APP))
pmid:16290302	act(p(HGNC:BACE1), ma(pep)) directlyIncreases deg(p(HGNC:APP))
pmid:16888322	act(p(HGNC:BACE1), ma(pep)) directlyIncreases deg(p(HGNC:APP))
pmid:17205046	act(p(HGNC:BACE1), ma(pep)) directlyIncreases deg(p(HGNC:APP))
pmid:17573534	act(p(HGNC:BACE1), ma(pep)) directlyIncreases deg(p(HGNC:APP))
pmid:17611486	act(p(HGNC:BACE1), ma(pep)) directlyIncreases deg(p(HGNC:APP))
pmid:17908048	act(p(HGNC:BACE1), ma(pep)) directlyIncreases deg(p(HGNC:APP))
pmid:18162398	act(p(HGNC:BACE1), ma(pep)) directlyIncreases deg(p(HGNC:APP))
pmid:19729516	act(p(HGNC:BACE1), ma(pep)) directlyIncreases deg(p(HGNC:APP))
pmid:15467394	act(p(HGNC:BACE1), ma(pep)) directlyIncreases deg(p(HGNC:APP))
pmid:15473697	act(p(HGNC:BACE1), ma(pep)) directlyIncreases deg(p(HGNC:APP))
pmid:16979658	act(p(HGNC:BACE1), ma(pep)) directlyIncreases deg(p(HGNC:APP))
pmid:17121991	act(p(HGNC:BACE1), ma(pep)) directlyIncreases deg(p(HGNC:APP))
pmid:22613765	act(p(HGNC:BACE1), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta"), p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")))
pmid:19519303	act(p(HGNC:BACE1)) increases p(HGNC:APP, frag("672_713"))
pmid:17995932	act(p(HGNC:BACE1), ma(pep)) increases p(HGNC:APP, frag("672_713"))
pmid:21431475	act(p(HGNC:BACE1), ma(pep)) increases p(HGNC:APP, frag("672_713"))
pmid:11953452	act(p(HGNC:BACE1), ma(pep)) increases p(HGNC:APP, frag("672_713"))
pmid:15584903	act(p(HGNC:BACE1), ma(pep)) increases p(HGNC:APP, frag("672_713"))
pmid:15767460	act(p(HGNC:BACE1), ma(pep)) increases p(HGNC:APP, frag("672_713"))
pmid:16216580	act(p(HGNC:BACE1), ma(pep)) increases p(HGNC:APP, frag("672_713"))
pmid:17098871	act(p(HGNC:BACE1), ma(pep)) increases p(HGNC:APP, frag("672_713"))
pmid:21718295	p(HGNC:BACE1) decreases p(HGNC:APP, frag("672_713"))
pmid:21246057	act(p(HGNC:BACE1)) increases p(HGNC:APP, frag("672_713"))
pmid:21431475	p(HGNC:BACE1) increases p(HGNC:APP, frag("672_713"))
pmid:19519303	act(p(HGNC:BACE1)) increases p(HGNC:APP, frag("672_711"))
pmid:22178568	p(HGNC:BACE1) association m(HGNC:"MIR124-1")
pmid:18234899	p(HGNC:BACE1) negativeCorrelation m(HGNC:MIR107)
pmid:11813874	act(p(HGNC:BACE1), ma(pep)) increases a(HBP:"sAPP-alpha")
pmid:15671026	act(p(HGNC:BACE1), ma(pep)) association p(HGNC:PAWR)
pmid:18079026	act(p(HGNC:BACE1), ma(pep)) increases p(HGNC:APP, frag("672_770"))
pmid:12423249	act(p(HGNC:BACE1), ma(pep)) increases p(HGNC:APP, frag("672_770"))
pmid:14530380	act(p(HGNC:BACE1), ma(pep)) association a(CHEBI:"heparan sulfate")
pmid:17223266	act(p(HGNC:BACE1), ma(pep)) association p(HGNC:NFKB1)
pmid:19332646	act(p(HGNC:BACE1), ma(pep)) association p(HGNC:AGER)
pmid:20097758	act(p(HGNC:BACE1), ma(pep)) association p(HGNC:ATXN1)
pmid:20092570	p(HGNC:BACE1) orthologous p(MGI:Bace1)
pmid:11744168	act(p(HGNC:BACE1), ma(pep)) directlyIncreases bp(GOBP:"apoptotic process")
pmid:20595388	act(p(HGNC:BACE1)) increases rxn(reactants(p(HGNC:APP)), products(p(HGNC:APP, frag("672_713"))))
pmid:22580286	complex(a(MESHC:"Lipoproteins, LDL"), p(HGNC:APOB)) increases a(CHEBI:"amyloid-beta")
pmid:22580286	complex(a(MESHC:"Lipoproteins, LDL"), p(HGNC:APOB)) increases a(CHEBI:cholesterol)
pmid:22580286	complex(a(MESHC:"Lipoproteins, LDL"), p(HGNC:APOB)) increases p(HGNC:BACE1)
pmid:22580286	complex(a(MESHC:"Lipoproteins, LDL"), p(HGNC:APOB)) increases act(p(HGNC:BACE1))
pmid:22580286	complex(a(MESHC:"Lipoproteins, LDL"), p(HGNC:APOB)) increases p(HGNC:MAPT, pmod(Ph))
pmid:22580286	complex(a(MESHC:"Lipoproteins, LDL"), p(HGNC:APOB)) decreases p(HGNC:SYP)
pmid:20061608	a(MESHC:"Lipoproteins, LDL") positiveCorrelation p(HGNC:APP, frag("672_713"))
pmid:20651816	complex(complex(SCOMP:"gamma Secretase Complex"), p(HGNC:APP), p(HGNC:BACE1)) directlyIncreases a(CHEBI:"amyloid-beta")
pmid:11877420	complex(p(HGNC:APBA1), p(HGNC:APP)) association bp(GOBP:"apoptotic process")
pmid:14756819	complex(p(HGNC:APBA1), p(HGNC:APP)) decreases a(CHEBI:"amyloid-beta")
pmid:12849748	complex(p(HGNC:APBA1), p(HGNC:APP)) decreases p(HGNC:APP, frag("672_713"))
pmid:22496686	p(HGNC:APBA1) association composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP))
pmid:22355143	p(HGNC:APBA1) association path(MESHD:"Alzheimer Disease")
pmid:10806097	p(HGNC:APBA1) decreases rxn(reactants(p(HGNC:APP)), products(p(HGNC:APP, frag("672_713"))))
pmid:18650430	p(HGNC:APBA1) association a(HBP:"YENPTY endocytosis motif (APP)")
pmid:22496686	p(HGNC:APBA1) decreases act(complex(SCOMP:"gamma Secretase Complex"), ma(pep))
pmid:22496686	p(HGNC:APBA1) decreases p(HGNC:APP, frag("672_713"))
pmid:22122372	p(HGNC:APBA1) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:17428983	complex(p(HGNC:APBA1), p(HGNC:APP), p(HGNC:LRP8)) increases complex(p(HGNC:APOE), p(HGNC:LRP8))
pmid:22429478	deg(p(HGNC:LRP8)) association complex(p(HGNC:APBB1), p(HGNC:LRP8))
pmid:10936878	p(HGNC:LRP8) increases path(MESHD:"Alzheimer Disease")
pmid:22496686	act(p(HGNC:LRP8)) association path(MESHD:"Alzheimer Disease")
pmid:22496686	p(HGNC:LRP8) association deg(p(HGNC:APP))
pmid:22496686	p(HGNC:LRP8) association p(HGNC:RELN)
pmid:22496686	act(p(HGNC:LRP8)) decreases act(p(HGNC:RELN))
pmid:22496686	p(HGNC:LRP8) association p(HGNC:GRIN2B)
pmid:22496686	p(HGNC:LRP8) association p(HGNC:GRIN2A)
pmid:22496686	p(HGNC:LRP8) association bp(GOBP:"regulation of long-term synaptic potentiation")
pmid:22496686	act(p(HGNC:LRP8)) decreases bp(GOBP:"reelin-mediated signaling pathway")
pmid:22355143	complex(p(HGNC:APBA1, var("p.Tyr633X")), p(HGNC:APP)) increases a(CHEBI:"amyloid-beta")
pmid:22496686	p(HGNC:APBA2) association composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP))
pmid:18650430	p(HGNC:APBA2) association a(HBP:"YENPTY endocytosis motif (APP)")
pmid:22496686	p(HGNC:APBA2) decreases act(complex(SCOMP:"gamma Secretase Complex"), ma(pep))
pmid:22496686	p(HGNC:APBA2) decreases p(HGNC:APP, frag("672_713"))
pmid:22122372	p(HGNC:APBA2) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:17428983	complex(p(HGNC:APBA2), p(HGNC:APP), p(HGNC:LRP8)) increases complex(p(HGNC:APOE), p(HGNC:LRP8))
pmid:12780348	complex(p(HGNC:APBA2), p(HGNC:NECAB3)) decreases complex(p(HGNC:APBA2), p(HGNC:APP))
pmid:19035353	p(HGNC:NECAB3) association p(HGNC:APP, frag("672_711"))
pmid:17428983	complex(p(HGNC:APBA3), p(HGNC:APP), p(HGNC:LRP8)) increases complex(p(HGNC:APOE), p(HGNC:LRP8))
pmid:22496686	p(HGNC:APBA3) association composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP))
pmid:18650430	p(HGNC:APBA3) association a(HBP:"YENPTY endocytosis motif (APP)")
pmid:22496686	p(HGNC:APBA3) decreases act(complex(SCOMP:"gamma Secretase Complex"), ma(pep))
pmid:22496686	p(HGNC:APBA3) decreases p(HGNC:APP, frag("672_713"))
pmid:22122372	p(HGNC:APBA3) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22496686	complex(p(HGNC:APBB1), p(HGNC:APP)) increases bp(GOBP:"neuron apoptotic process")
pmid:11877420	complex(p(HGNC:APBB1), p(HGNC:APP)) association bp(GOBP:"apoptotic process")
pmid:18833287	complex(p(HGNC:APBB1), p(HGNC:APP)) increases a(CHEBI:"amyloid-beta")
pmid:22496686	complex(p(HGNC:APBB1), p(HGNC:APP)) association bp(GOBP:"cellular response to DNA damage stimulus")
pmid:22496686	p(HGNC:APBB1) association composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP))
pmid:19334058	act(p(HGNC:APBB1)) regulates p(HGNC:APP)
pmid:11337355	p(HGNC:APBB1) association path(MESHD:"Alzheimer Disease")
pmid:11517218	p(HGNC:APBB1) decreases a(CHEBI:"amyloid-beta")
pmid:10806097	p(HGNC:APBB1) increases rxn(reactants(p(HGNC:APP)), products(p(HGNC:APP, frag("672_713"))))
pmid:22429478	p(HGNC:APBB1) increases complex(p(HGNC:APP), p(HGNC:VLDLR))
pmid:22429478	p(HGNC:APBB1) association p(HGNC:VLDLR)
pmid:18650430	p(HGNC:APBB1) association a(HBP:"YENPTY endocytosis motif (APP)")
pmid:18650430	p(HGNC:APBB1) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22122372	p(HGNC:APBB1) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:20637285	p(HGNC:APBB1) increases complex(p(HGNC:APP), p(HGNC:LRP1))
pmid:22156573	complex(p(HGNC:APBB1), p(HGNC:APP), p(HGNC:KLC1)) increases act(p(HGNC:MAPK8), ma(kin))
pmid:15364413	p(HGNC:KLC1) association p(HGNC:APP)
pmid:25394182	p(HGNC:KLC1) association p(HGNC:APP)
pmid:22434822	p(HGNC:KLC1) association act(p(HGNC:APP), ma(tport))
pmid:22272245	act(p(HGNC:KLC1)) increases p(HGNC:MAPT)
pmid:18164103	p(HGNC:KLC1) association p(HGNC:MAPT)
pmid:22272245	p(HGNC:KLC1) increases p(HGNC:MAPT)
pmid:22272245	act(p(HGNC:KLC1)) increases tloc(a(CHEBI:"amyloid-beta"), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:25394182	p(HGNC:KLC1) increases a(CHEBI:"amyloid-beta")
pmid:22122372	p(HGNC:KLC1) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22429478	complex(p(HGNC:APBB1), p(HGNC:APP), p(HGNC:LRP1)) association deg(p(HGNC:APP))
pmid:23167255	complex(p(HGNC:APBB1), p(HGNC:APP), p(HGNC:LRP1)) increases act(p(HGNC:APP))
pmid:18650430	complex(p(HGNC:APBB1), p(HGNC:APP), p(HGNC:LRP1)) increases tloc(p(HGNC:APP))
pmid:21968187	complex(p(HGNC:APBB1), p(HGNC:APP), p(HGNC:LRP1)) increases a(CHEBI:"amyloid-beta")
pmid:21968187	complex(p(HGNC:APBB1), p(HGNC:APP), p(HGNC:LRP1)) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:22156573	act(complex(p(HGNC:APBB1), p(HGNC:KLC1)), ma(tport)) increases tloc(p(HGNC:APP))
pmid:22156573	act(complex(p(HGNC:APBB1), p(HGNC:KLC1)), ma(tport)) increases tloc(p(HGNC:APP))
pmid:22429478	complex(p(HGNC:APBB1), p(HGNC:LRP8)) association deg(p(HGNC:LRP8))
pmid:15686969	complex(p(HGNC:APBB1), p(HGNC:MAPT)) association act(p(HGNC:GSK3B))
pmid:15686969	complex(p(HGNC:APBB1), p(HGNC:MAPT)) association act(p(HGNC:CDK5), ma(kin))
pmid:15686969	complex(p(HGNC:APBB1), p(HGNC:MAPT)) association p(HGNC:MAPT, pmod(Ph))
pmid:17360687	p(HGNC:MAPT) decreases bp(GOBP:"apoptotic process")
pmid:25024322	p(HGNC:MAPT) positiveCorrelation p(HGNC:CHI3L1)
pmid:25865441	p(HGNC:MAPT) positiveCorrelation p(HGNC:CHI3L1)
pmid:25865441	p(HGNC:MAPT) positiveCorrelation p(HGNC:CHI3L1)
pmid:26836182	p(HGNC:MAPT) positiveCorrelation p(HGNC:CHI3L1)
pmid:26836182	p(HGNC:MAPT) positiveCorrelation p(HGNC:CHI3L1)
pmid:19885299	p(HGNC:MAPT) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:14699432	p(HGNC:MAPT) biomarkerFor path(MESHD:"Alzheimer Disease")
pmid:12428805	p(HGNC:MAPT) association path(MESHD:"Alzheimer Disease")
pmid:15686969	p(HGNC:MAPT) association path(MESHD:"Alzheimer Disease")
pmid:18675468	p(HGNC:MAPT) association bp(GOBP:"regulation of microtubule cytoskeleton organization")
pmid:22110360	p(HGNC:MAPT) association p(HGNC:DYRK1A)
pmid:22078238	p(HGNC:MAPT) negativeCorrelation p(HGNC:GAL)
pmid:24884485	p(HGNC:MAPT) negativeCorrelation path(MESH:D060825)
pmid:20157251	p(HGNC:MAPT) decreases complex(p(HGNC:BCL2), p(HGNC:PPP2CA))
pmid:21367866	p(HGNC:MAPT) association bp(PTS:"chaperone signaling pathway")
pmid:12428805	p(HGNC:MAPT) association path(MESHD:"Frontotemporal Dementia")
pmid:12428805	p(HGNC:MAPT) association path(MESHD:"Supranuclear Palsy, Progressive")
pmid:17154549	deg(p(HGNC:MAPT)) association p(HGNC:NPEPPS)
PubMed Central:PMC21391	p(HGNC:MAPT) association p(HGNC:PSEN1)
pmid:24884485	p(HGNC:MAPT) negativeCorrelation bp(GOBP:cognition)
pmid:26235064	p(HGNC:MAPT) association bp(GOBP:cognition)
pmid:26235064	p(HGNC:MAPT) association bp(GOBP:"neuron death")
pmid:3122646	p(HGNC:MAPT) association a(NIFT:"White matter")
pmid:18164103	p(HGNC:MAPT) association p(HGNC:KLC1)
pmid:26402072	p(HGNC:MAPT) association p(HGNC:TIMP1)
pmid:26402072	p(HGNC:MAPT) association p(SFAM:"MMP Family")
pmid:22122372	complex(p(HGNC:APBB2), p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")) increases bp(GOBP:"positive regulation of protein neddylation")
pmid:22122372	complex(p(HGNC:APBB2), p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")) decreases p(HGNC:CTNNB1)
pmid:22122372	complex(p(HGNC:APBB2), p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")) increases bp(GOBP:"apoptotic process")
pmid:22122372	p(HGNC:APBB2) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:18650430	p(HGNC:APBB2) association a(HBP:"YENPTY endocytosis motif (APP)")
pmid:21034527	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") increases act(p(HGNC:TAGLN))
pmid:21034527	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") increases act(p(HGNC:ACTA2))
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") increases act(p(HGNC:GSK3B))
pmid:22613765	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") directlyIncreases act(p(HGNC:GSK3B))
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:APBB2)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association bp(GOBP:"calcium ion homeostasis")
pmid:18675468	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") decreases bp(GOBP:"calcium ion homeostasis")
pmid:18675468	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association bp(GOBP:"regulation of transcription, DNA-templated")
pmid:19306298	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:MME)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") increases act(p(HGNC:TP53))
pmid:22613765	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") increases complex(p(HGNC:APC), p(HGNC:CSNK1A1), p(HGNC:CTNNB1), p(HGNC:GSK3B), p(SFAM:"AXIN Family"))
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") increases act(p(MGI:Gsk3b))
pmid:22122372	tloc(p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site"), fromLoc(MESHCS:Cytoplasm), toLoc(MESHCS:"Cell Nucleus")) positiveCorrelation act(p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site"))
pmid:22122372	act(p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")) positiveCorrelation tloc(p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site"), fromLoc(MESHCS:Cytoplasm), toLoc(MESHCS:"Cell Nucleus"))
pmid:22122372	act(p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")) regulates r(HGNC:GSK3B)
pmid:22122372	act(p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")) regulates p(SFAM:"EGFR/ERBB Family")
pmid:18650430	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:APBB1)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:APBB1)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:KLC1)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:KLC2)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:KLC3)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:KLC4)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:SHC1)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:SHC2)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:SHC3)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:SHC4)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:NUMB)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:APBA1)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:APBA2)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:APBA3)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:CLTA)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:CLTB)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:CLTC)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:DAB1)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:APPBP2)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:SUV39H1)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:SUV39H2)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:KMT5B)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:EZH1)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:EZH2)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association g(HGNC:EZH2P1)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:MLLT6)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association g(HGNC:MLLT10P1)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:MLLT1)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:MLLT3)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:AFDN)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association g(HGNC:MLLT10P2)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:MLLT11)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:MLLT10)
pmid:22122372	p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site") association p(HGNC:KMT2A)
pmid:22122372	tloc(p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site"), fromLoc(MESHCS:Cytoplasm), toLoc(MESHCS:"Cell Nucleus")) regulates g(HGNC:LRP1)
pmid:22122372	tloc(p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site"), fromLoc(MESHCS:Cytoplasm), toLoc(MESHCS:"Cell Nucleus")) regulates g(HGNC:TP53)
pmid:23296004	complex(p(HGNC:APH1A), p(HGNC:ARRB2)) association act(complex(SCOMP:"gamma Secretase Complex"), ma(pep))
pmid:12297508	p(HGNC:APH1A) increases p(HGNC:PSEN1)
pmid:12297508	p(HGNC:APH1A) increases p(HGNC:APP)
pmid:12297508	p(HGNC:APH1A) increases p(HGNC:NOTCH1)
pmid:12297508	p(HGNC:APH1A) increases a(CHEBI:"amyloid-beta")
pmid:12471034	p(HGNC:APH1A) association complex(p(HGNC:NOTCH1), p(HGNC:PSEN1))
pmid:23296004	p(HGNC:ARRB2) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:23296004	p(HGNC:ARRB2) increases p(HGNC:GPR3)
pmid:19885829	complex(p(HGNC:APH1A), p(HGNC:NCSTN), p(HGNC:PSEN1), p(HGNC:PSENEN)) increases a(CHEBI:"amyloid-beta")
pmid:16973241	act(p(HGNC:NCSTN)) directlyIncreases deg(p(HGNC:APP))
pmid:10993067	p(HGNC:NCSTN) association a(CHEBI:"amyloid-beta")
pmid:16423463	p(HGNC:NCSTN) association a(CHEBI:"amyloid-beta")
pmid:19394408	p(HGNC:NCSTN) association a(CHEBI:"amyloid-beta")
pmid:10993067	p(HGNC:NCSTN) increases a(CHEBI:"amyloid-beta")
pmid:12639958	p(HGNC:PSENEN) positiveCorrelation bp(GOBP:"Notch signaling pathway")
pmid:12639958	p(HGNC:PSENEN) positiveCorrelation p(HGNC:APP, frag("672_713"))
pmid:11523796	complex(p(HGNC:APOE), p(HGNC:APP)) association tloc(p(HGNC:APP), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:21297948	complex(p(HGNC:APOE), p(HGNC:APP)) association path(MESHD:"Alzheimer Disease")
pmid:11523796	complex(p(HGNC:APOE), p(HGNC:APP)) association bp(PTS:"APP processing pathway")
pmid:11523796	complex(p(HGNC:APOE), p(HGNC:APP)) association a(CHEBI:"amyloid-beta")
pmid:17077814	complex(p(HGNC:APOE), p(HGNC:APP, frag("672_711"))) decreases tloc(p(HGNC:APP, frag("672_711")), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:17077814	complex(p(HGNC:APOE), p(HGNC:APP, frag("672_713"))) increases tloc(p(HGNC:APP, frag("672_713")), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:8823200	complex(p(HGNC:APOE), p(HGNC:APP, frag("672_713"))) increases complex(GOCC:"neurofibrillary tangle")
pmid:21873229	complex(p(HGNC:APOE), p(HGNC:APP, frag("672_713"))) association path(MESHD:"Alzheimer Disease")
pmid:20847424	complex(p(HGNC:APOE), p(HGNC:APP, frag("672_713"))) increases bp(GOBP:"cholesterol transport")
pmid:20847424	complex(p(HGNC:APOE), p(HGNC:APP, frag("672_713"))) increases bp(GOBP:"synapse assembly")
pmid:17428983	complex(p(HGNC:APOE), p(HGNC:LRP8)) increases tloc(p(HGNC:LRP8), fromLoc(MESHCS:"Cell Surface Extensions"), toLoc(MESHCS:Endosomes))
pmid:17428983	complex(p(HGNC:APOE), p(HGNC:LRP8)) increases tloc(p(HGNC:APP), fromLoc(MESHCS:"Cell Surface Extensions"), toLoc(MESHCS:Endosomes))
pmid:17428983	complex(p(HGNC:APOE), p(HGNC:LRP8)) increases tloc(p(HGNC:BACE1), fromLoc(MESHCS:"Cell Surface Extensions"), toLoc(MESHCS:Endosomes))
pmid:17428983	complex(p(HGNC:APOE), p(HGNC:LRP8)) increases tloc(p(HGNC:BACE2), fromLoc(MESHCS:"Cell Surface Extensions"), toLoc(MESHCS:Endosomes))
pmid:10931940	complex(p(HGNC:APP), p(HGNC:BACE1)) increases a(CHEBI:"amyloid-beta")
pmid:19729516	complex(p(HGNC:APP), p(HGNC:BACE1), p(HGNC:LRP1), p(HGNC:RANBP9)) increases a(CHEBI:"amyloid-beta")
pmid:19251705	p(HGNC:RANBP9) increases complex(p(HGNC:APP), p(HGNC:BACE1))
pmid:22223749	p(HGNC:RANBP9) increases complex(p(HGNC:APP), p(HGNC:BACE1))
pmid:19251705	p(HGNC:RANBP9) increases complex(p(HGNC:APP), p(HGNC:LRP1))
pmid:22223749	p(HGNC:RANBP9) increases bp(HBP:amyloidogenesis)
pmid:22223749	p(HGNC:RANBP9) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:19251705	p(HGNC:RANBP9) decreases p(HGNC:APP, frag("672_713"))
pmid:16252002	complex(p(HGNC:APP), p(HGNC:CALR)) increases bp(GOBP:endocytosis)
pmid:16252002	complex(p(HGNC:APP), p(HGNC:CLTA)) increases bp(GOBP:endocytosis)
pmid:22122372	p(HGNC:CLTA) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:16252002	complex(p(HGNC:APP), p(HGNC:CLTB)) increases bp(GOBP:endocytosis)
pmid:22122372	p(HGNC:CLTB) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:16252002	complex(p(HGNC:APP), p(HGNC:CLTC)) increases bp(GOBP:endocytosis)
pmid:22122372	p(HGNC:CLTC) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22355794	complex(p(HGNC:APP), p(HGNC:COL1A1)) association bp(GOBP:"cell-matrix adhesion")
pmid:22355794	p(HGNC:COL1A1) increases bp(GOBP:"cell-matrix adhesion")
pmid:22496686	complex(p(HGNC:APP), p(HGNC:DAB2)) association p(HGNC:RELN)
pmid:22496686	complex(p(HGNC:APP), p(HGNC:DAB2)) increases p(HGNC:APP, frag("672_711"))
pmid:22496686	p(HGNC:DAB2) association composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP))
pmid:22496686	complex(p(HGNC:APP), p(HGNC:GRB2)) association p(HGNC:APP, pmod(Ph, Tyr))
pmid:12084708	complex(p(HGNC:APP), p(HGNC:GRB2)) association bp(GOBP:"signal transduction")
pmid:22496686	p(HGNC:GRB2) association p(HGNC:APP, pmod(Ph, Tyr, 682))
pmid:20847424	p(HGNC:GRB2) association act(p(HGNC:IRS1, pmod(Ph, Thr)))
pmid:20847424	p(HGNC:GRB2) increases act(p(HGNC:PDPK1))
pmid:20847424	p(HGNC:GRB2) association act(p(HGNC:IRS2, pmod(Ph, Thr)))
pmid:20847424	p(HGNC:GRB2) increases act(p(HGNC:GSK3B))
pmid:20847424	p(HGNC:GRB2) increases act(p(HGNC:GSK3A))
pmid:22496686	complex(p(HGNC:APP), p(HGNC:GRB2), p(HGNC:PSEN1)) increases act(p(SFAM:"MAPK Erk1/2 Family"))
pmid:22355794	complex(p(HGNC:APP), p(HGNC:HDGF)) association bp(GOBP:"cell-matrix adhesion")
pmid:22355794	p(HGNC:HDGF) increases bp(GOBP:"cell-matrix adhesion")
pmid:15974929	complex(p(HGNC:APP), p(HGNC:LMTK2)) increases a(CHEBI:"amyloid-beta")
pmid:12212791	complex(p(HGNC:APP), p(HGNC:LRP1)) regulates deg(p(HGNC:APP))
pmid:20637285	complex(p(HGNC:APP), p(HGNC:LRP1)) regulates tloc(p(HGNC:APP), fromLoc(GOCC:"cell surface"), toLoc(GOCC:intracellular))
pmid:11877420	complex(p(HGNC:APP), p(HGNC:MAPK8IP1)) association bp(GOBP:"apoptotic process")
pmid:22496686	p(HGNC:MAPK8IP1) association composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP))
pmid:12917434	p(HGNC:MAPK8IP1) increases p(HGNC:APP, pmod(Ph))
pmid:11489281	complex(p(HGNC:APP), p(HGNC:PSEN1)) association path(MESHD:"Alzheimer Disease")
pmid:9055862	complex(p(HGNC:APP), p(HGNC:PSEN2)) decreases tloc(p(HGNC:APP), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:17314098	p(HGNC:PSEN2) association path(MESHD:"Alzheimer Disease")
pmid:14585504	p(HGNC:PSEN2) association path(MESHD:"Alzheimer Disease")
pmid:22382662	p(HGNC:PSEN2) association path(MESHD:"Alzheimer Disease")
pmid:22115042	act(p(HGNC:PSEN2)) increases p(HGNC:APP)
pmid:16973241	act(p(HGNC:PSEN2)) directlyIncreases deg(p(HGNC:APP))
pmid:12684521	p(HGNC:PSEN2) increases deg(p(HGNC:APP))
pmid:22115042	act(p(HGNC:PSEN2)) increases bp(GOBP:"positive regulation of neuron apoptotic process")
pmid:10037471	p(HGNC:PSEN2) increases a(CHEBI:"amyloid-beta")
pmid:12147673	p(HGNC:PSEN2) increases a(CHEBI:"amyloid-beta")
pmid:12603837	p(HGNC:PSEN2) increases a(CHEBI:"amyloid-beta")
pmid:10967351	p(HGNC:PSEN2) association bp(GOBP:"Notch signaling pathway")
pmid:22496686	complex(p(HGNC:APP), p(HGNC:RELN)) increases tloc(p(HGNC:APP), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:22496686	p(HGNC:RELN) association complex(p(HGNC:APP), p(HGNC:DAB2))
pmid:22496686	act(p(HGNC:RELN)) decreases path(MESHD:"Alzheimer Disease")
pmid:22496686	act(p(HGNC:RELN)) increases p(HGNC:GRIN2A, pmod(Ph))
pmid:22496686	act(p(HGNC:RELN)) increases p(HGNC:GRIN2B, pmod(Ph))
pmid:19515914	p(HGNC:RELN) association p(HGNC:APP)
pmid:19515914	p(HGNC:RELN) increases bp(GOBP:"neuron projection development")
pmid:19515914	p(HGNC:RELN) increases p(HGNC:DAB1, pmod(Ph))
pmid:19515914	p(HGNC:RELN) increases p(HGNC:DAB1, pmod(Ph))
pmid:19515914	p(HGNC:RELN) increases bp(GOBP:"regulation of neuron migration")
pmid:19515914	p(HGNC:RELN) increases bp(GOBP:"regulation of neuron migration")
pmid:19515914	p(HGNC:RELN) association p(HGNC:ITGB1)
pmid:22496686	p(HGNC:RELN) association p(HGNC:LRP8)
pmid:22496686	p(HGNC:RELN) association bp(GOBP:"neural tube development")
pmid:22496686	act(p(HGNC:RELN)) association bp(GOBP:"reelin-mediated signaling pathway")
pmid:22496686	complex(p(HGNC:APP), p(HGNC:SHC1)) increases act(p(SFAM:"MAPK Erk1/2 Family"))
pmid:12084708	complex(p(HGNC:APP), p(HGNC:SHC1)) association bp(GOBP:"signal transduction")
pmid:22496686	p(HGNC:SHC1) association p(HGNC:APP, pmod(Ph, Tyr, 682))
pmid:22122372	p(HGNC:SHC1) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22122372	p(HGNC:SHC2) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22496686	complex(p(HGNC:APP), p(HGNC:SHC3)) increases act(p(SFAM:"MAPK Erk1/2 Family"))
pmid:22122372	p(HGNC:SHC3) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22787047	p(HGNC:SRC) increases p(HGNC:APBA2, pmod(Ph))
pmid:14766758	p(HGNC:SRC) increases deg(p(HGNC:APP))
pmid:22496686	p(HGNC:VLDLR) association p(HGNC:APOE)
pmid:22429478	p(HGNC:VLDLR) association p(HGNC:APBB1)
pmid:9338779	complex(p(HGNC:APP, frag("672_713")), p(HGNC:HSD17B10)) association act(a(MESH:D009474))
pmid:20847424	complex(p(HGNC:APP, frag("672_713")), p(HGNC:HSD17B10)) increases a(MESHC:"Free Radicals")
pmid:22523685	complex(p(HGNC:APP, frag("672_713")), p(HGNC:HSD17B10)) decreases act(a(MESH:D008928))
pmid:20847424	complex(p(HGNC:APP, frag("672_713")), p(HGNC:HSD17B10)) increases a(CHEBI:"reactive oxygen species")
pmid:20847424	complex(p(HGNC:APP, frag("672_713")), p(HGNC:HSD17B10)) increases bp(GOBP:"apoptotic process")
pmid:15294142	complex(p(HGNC:APP, frag("672_713")), p(HGNC:LRP1)) increases path(HBP:neurotoxicity)
pmid:11943163	complex(p(HGNC:APP, frag("672_713")), p(HGNC:MAPT)) increases p(HGNC:MAPT, pmod(Ph))
pmid:18650430	complex(p(HGNC:APP, frag("672_713")), p(HGNC:PRNP)) decreases bp(GOBP:"regulation of synaptic plasticity")
pmid:22036569	complex(p(HGNC:ARC), p(HGNC:PSEN1)) increases act(complex(SCOMP:"gamma Secretase Complex"))
pmid:22036569	p(HGNC:ARC) increases tloc(p(HGNC:APP), fromLoc(MESHCS:"Cell Membrane"), toLoc(MESHCS:Endosomes))
pmid:15466887	complex(p(HGNC:BACE1), p(HGNC:GGA1)) association p(HGNC:BACE1, pmod(Ph))
pmid:12402041	complex(p(HGNC:CD40), p(HGNC:CD40LG)) increases bp(GOBP:"microglial cell activation")
pmid:15688347	complex(p(HGNC:CD40), p(HGNC:CD40LG)) association bp(GOBP:"immune response")
pmid:15688347	complex(p(HGNC:CD40), p(HGNC:CD40LG)) increases bp(GOBP:"cytokine production involved in inflammatory response")
pmid:19499146	complex(p(HGNC:CTSD), p(HGNC:TP53)) increases bp(GOBP:"apoptotic process")
pmid:19499146	p(HGNC:CTSD) increases deg(p(HGNC:APP))
pmid:10605825	p(HGNC:CTSD) increases deg(p(HGNC:APP))
pmid:10605825	p(HGNC:CTSD) increases deg(p(HGNC:APP))
pmid:8943232	act(p(HGNC:CTSD), ma(pep)) increases deg(p(HGNC:APP))
pmid:7523115	act(p(HGNC:CTSD), ma(pep)) increases deg(p(HGNC:APP))
pmid:7523115	act(p(HGNC:CTSD), ma(pep)) association deg(p(HGNC:APP))
pmid:8930981	act(p(HGNC:CTSD), ma(pep)) increases deg(p(HGNC:APP))
pmid:19499146	p(HGNC:CTSD) increases bp(GOBP:"apoptotic process")
pmid:19499146	p(HGNC:CTSD) increases deg(p(HGNC:BID))
pmid:19499146	p(HGNC:CTSD) increases a(CHEBI:"amyloid-beta polypeptide 42")
pmid:19499146	act(p(HGNC:TP53), ma(tscript)) increases act(p(HGNC:CTSD))
pmid:22122372	act(p(HGNC:TP53)) increases bp(GOBP:"apoptotic process")
pmid:14744432	p(HGNC:TP53) association p(HGNC:CYCS)
pmid:14744432	p(HGNC:TP53) association p(HGNC:BAX)
pmid:14744432	p(HGNC:TP53) association p(HGNC:BAD)
pmid:23164821	p(HGNC:TP53) increases r(HGNC:DKK1)
pmid:22500019	complex(p(HGNC:IAPP), p(HGNC:RAMP1)) increases act(p(HGNC:IAPP))
pmid:22500019	complex(p(HGNC:IAPP), p(HGNC:RAMP2)) increases act(p(HGNC:IAPP))
pmid:22500019	complex(p(HGNC:IAPP), p(HGNC:RAMP3)) increases act(p(HGNC:RAMP3))
pmid:22122372	complex(p(HGNC:MAPK8IP1), p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")) increases p(HGNC:APP, pmod(Ph, Thr, 668))
pmid:22122372	complex(p(HGNC:MAPK8IP2), p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")) increases p(HGNC:APP, pmod(Ph, Thr, 668))
pmid:22496686	p(HGNC:MAPK8IP2) association p(HGNC:APP)
pmid:22496686	p(HGNC:MAPK8IP2) decreases p(HGNC:APP, frag("672_713"))
pmid:22122372	complex(p(HGNC:MAPK8IP3), p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")) increases p(HGNC:APP, pmod(Ph, Thr, 668))
pmid:12297508	complex(p(HGNC:NCSTN), p(HGNC:PSEN1)) increases deg(p(HGNC:APP))
pmid:12297508	complex(p(HGNC:NCSTN), p(HGNC:PSEN1)) increases deg(p(HGNC:NOTCH1))
pmid:11327298	complex(p(HGNC:PLAU), p(HGNC:PLAUR)) increases act(p(HGNC:MMP9), ma(pep))
pmid:21192821	complex(p(HGNC:ROCK2), p(HGNC:SORL1)) increases a(HBP:"sAPP-alpha")
pmid:21192821	p(HGNC:ROCK2) increases a(CHEBI:"amyloid-beta")
pmid:16930450	p(HGNC:SORL1) association a(CHEBI:"amyloid-beta")
pmid:22727043	act(p(HGNC:SORL1), ma(tport)) decreases tloc(p(HGNC:APP), fromLoc(MESHCS:"trans-Golgi Network"), toLoc(MESHCS:"Cell Membrane"))
pmid:22727043	act(p(HGNC:SORL1), ma(tport)) decreases tloc(p(HGNC:APP), fromLoc(MESHCS:"Cell Membrane"), toLoc(MESHCS:Endosomes))
pmid:26996954	p(HGNC:SORL1) association p(HGNC:APP)
pmid:26996954	p(HGNC:SORL1) decreases p(HGNC:APP)
pmid:22727043	act(p(HGNC:SORL1), ma(tport)) directlyDecreases p(HGNC:APP, frag("672_713"))
pmid:26996954	p(HGNC:SORL1) increases p(HGNC:APP, frag("672_713"))
pmid:22472873	p(HGNC:SORL1) decreases p(HGNC:APP, frag("672_713"))
pmid:26996954	p(HGNC:SORL1) association g(DBSNP:rs3824968)
pmid:26996954	p(HGNC:SORL1) association a(NIFT:"Grey matter volume")
pmid:10527810	composite(a(CHEBI:"amyloid-beta"), p(HGNC:CASP8), p(HGNC:FADD)) increases bp(GOBP:"neuron apoptotic process")
pmid:10409650	p(HGNC:CASP8) increases deg(p(HGNC:APP))
pmid:10911620	p(HGNC:CASP8) increases deg(p(HGNC:APP))
pmid:15178331	p(HGNC:CASP8) increases deg(p(HGNC:APP))
pmid:19499146	act(p(HGNC:CASP8)) increases bp(GOBP:"apoptotic process")
pmid:18957217	p(HGNC:CASP8) decreases p(HGNC:APP, frag("672_713"))
pmid:15882940	composite(a(CHEBI:"amyloid-beta"), p(HGNC:CSF1)) increases r(HGNC:AGER)
pmid:21942811	p(HGNC:CSF1) biomarkerFor path(MESHD:"Alzheimer Disease")
pmid:24332564	composite(a(CHEBI:"amyloid-beta"), p(HGNC:NOS3), p(HGNC:PIN1)) association path(MESHD:"Alzheimer Disease")
pmid:24332564	composite(a(CHEBI:"amyloid-beta"), p(HGNC:NOS3), p(HGNC:PIN1)) association path(MESHD:Hypertension)
pmid:24332564	composite(a(CHEBI:"amyloid-beta"), p(HGNC:NOS3), p(HGNC:PIN1)) association path(MESHD:"Cerebral Amyloid Angiopathy")
pmid:24332564	p(HGNC:NOS3) association p(HGNC:PIN1)
pmid:24332564	p(HGNC:NOS3) association p(HGNC:APP, frag("672_713"))
pmid:24332564	p(HGNC:NOS3) decreases p(HGNC:APP, frag("672_713"))
pmid:24332564	p(HGNC:NOS3) decreases p(HGNC:APP, frag("672_713"))
pmid:16813604	p(HGNC:NOS3) association path(MESHD:"Alzheimer Disease")
pmid:15016421	p(HGNC:NOS3) regulates a(CHEBI:"nitric oxide")
pmid:12218642	p(HGNC:NOS3) association path(MESHD:Stroke)
pmid:22431227	p(HGNC:NOS3) association act(a(MESHC:Acetylcholinesterase))
pmid:22184106	p(HGNC:PIN1) decreases act(p(HGNC:GSK3B))
pmid:22184106	p(HGNC:PIN1) increases deg(p(HGNC:APP))
pmid:22184106	p(HGNC:PIN1) increases a(CHEBI:"amyloid-beta")
pmid:24332564	p(HGNC:PIN1) decreases a(CHEBI:"amyloid-beta")
pmid:24332564	p(HGNC:PIN1) association p(HGNC:NOS3)
pmid:24332564	p(HGNC:PIN1) increases act(p(HGNC:NOS3))
pmid:24332564	p(HGNC:PIN1) association p(HGNC:APP, frag("672_713"))
pmid:24332564	p(HGNC:PIN1) decreases p(HGNC:APP, frag("672_713"))
pmid:11432833	p(HGNC:PIN1) decreases bp(GOBP:"apoptotic process")
pmid:11432833	p(HGNC:PIN1) decreases bp(GOBP:"neuron death")
pmid:23362255	p(HGNC:PIN1) decreases p(HGNC:MAPT, pmod(Ph, Ser))
pmid:23362255	p(HGNC:PIN1) decreases act(p(HGNC:CDK5), ma(kin))
pmid:23362255	p(HGNC:PIN1) decreases p(HGNC:MAPT, pmod(Ph, Thr))
pmid:23362255	p(HGNC:PIN1) increases act(p(HGNC:PPP2CA), ma(phos))
pmid:22787047	composite(p(HGNC:APBA1), p(HGNC:APBA2), p(HGNC:APBA3)) increases act(p(HGNC:APP))
pmid:22787047	composite(p(HGNC:APBA1), p(HGNC:APBA2), p(HGNC:APBA3), p(HGNC:APP)) increases a(CHEBI:"amyloid-beta")
pmid:21199446	composite(p(HGNC:APBB1), p(HGNC:APP)) decreases bp(GOBP:"neuron projection development")
pmid:21034527	composite(p(HGNC:APBB1), p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")) decreases bp(GOBP:"regulation of actin filament binding")
pmid:21034527	composite(p(HGNC:APBB1), p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")) decreases bp(GOBP:"regulation of mitochondrial membrane potential")
pmid:22496686	composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP)) association p(HGNC:APBA1)
pmid:22496686	composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP)) association p(HGNC:APBA2)
pmid:22496686	composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP)) association p(HGNC:APBA3)
pmid:22496686	composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP)) association p(HGNC:APBB1)
pmid:22496686	composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP)) association p(HGNC:DAB2)
pmid:22496686	composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP)) association p(HGNC:ABL1)
pmid:22496686	composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP)) association p(HGNC:MAPK8IP1)
pmid:22496686	composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP)) association p(HGNC:NUMB)
pmid:22355794	p(HGNC:APLP1) association bp(GOBP:"neuron development")
pmid:22349563	p(HGNC:APLP1) association bp(GOBP:neurogenesis)
pmid:22349563	p(HGNC:APLP1) association bp(GOBP:"regulation of neuron migration")
pmid:22349563	p(HGNC:APLP1) association bp(GOBP:"neuron projection development")
pmid:22349563	p(HGNC:APLP1) association bp(GOBP:"neuron cell-cell adhesion")
pmid:22349563	p(HGNC:APLP2) association bp(GOBP:neurogenesis)
pmid:22349563	p(HGNC:APLP2) association bp(GOBP:"regulation of neuron migration")
pmid:22349563	p(HGNC:APLP2) association bp(GOBP:"neuron projection development")
pmid:22349563	p(HGNC:APLP2) association bp(GOBP:"neuron cell-cell adhesion")
pmid:18650430	composite(p(HGNC:APP), p(HGNC:COL9A1)) increases bp(GOBP:"cell adhesion")
pmid:18650430	composite(p(HGNC:APP), p(HGNC:LAMB1)) increases bp(GOBP:"cell adhesion")
pmid:22496686	composite(p(HGNC:APP), p(HGNC:PSEN1)) regulates bp(GOBP:"cell cycle")
pmid:12536224	composite(p(HGNC:APP, frag("672_713")), p(HGNC:C1QBP)) increases p(HGNC:IL6)
pmid:12536224	composite(p(HGNC:APP, frag("672_713")), p(HGNC:C1QBP)) increases p(HGNC:TNF)
pmid:12536224	composite(p(HGNC:APP, frag("672_713")), p(HGNC:C1QBP)) increases p(HGNC:IL1B)
pmid:12536224	composite(p(HGNC:APP, frag("672_713")), p(HGNC:C1QBP)) increases p(HGNC:IL1A)
pmid:11114266	composite(p(HGNC:IFNG), p(HGNC:IL1B)) increases a(CHEBI:"amyloid-beta")
pmid:26113788	p(HGNC:IFNG) increases bp(HBP:neuroinflammation)
pmid:20100581	p(HGNC:IFNG) association p(HGNC:NOS1)
pmid:22047170	composite(p(HGNC:IFNG), p(HGNC:TNF)) increases p(HGNC:APP)
pmid:22047170	composite(p(HGNC:IFNG), p(HGNC:TNF)) increases tloc(p(HGNC:APP, frag("672_711")), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:11114266	composite(p(HGNC:IFNG), p(HGNC:TNF)) increases a(CHEBI:"amyloid-beta")
pmid:24332564	composite(p(HGNC:NOS3), p(HGNC:PIN1)) decreases a(CHEBI:"amyloid-beta")
pmid:24332564	composite(p(HGNC:NOS3), p(HGNC:PIN1)) decreases a(CHEBI:"amyloid-beta")
pmid:24332564	composite(p(HGNC:NOS3), p(HGNC:PIN1)) increases bp(GOBP:vasodilation)
pmid:24332564	composite(p(HGNC:NOS3), p(HGNC:PIN1)) increases bp(GOBP:"regulation of blood pressure")
pmid:24332564	composite(p(HGNC:NOS3), p(HGNC:PIN1)) decreases p(HGNC:APP, frag("672_713"))
pmid:24332564	composite(p(HGNC:NOS3), p(HGNC:PIN1)) decreases path(MESHD:"Alzheimer Disease")
pmid:24332564	composite(p(HGNC:NOS3), p(HGNC:PIN1)) decreases path(MESHD:Hypertension)
pmid:24332564	composite(p(HGNC:NOS3), p(HGNC:PIN1)) decreases path(MESHD:"Cerebral Amyloid Angiopathy")
pmid:21769591	g(DBSNP:rs11542041) transcribedTo r(DBSNP:rs11542041)
pmid:19734902	g(DBSNP:rs1217338) association g(HGNC:APBA1)
pmid:19734902	g(DBSNP:rs12212067) association g(HGNC:FOXO3)
pmid:22107728	g(DBSNP:rs1887922) causesNoChange path(MESHD:"Alzheimer Disease")
pmid:22107728	g(DBSNP:rs1887922) causesNoChange path(MESHD:"Diabetes Mellitus, Type 2")
pmid:22107728	g(DBSNP:rs2251101) association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:19419557	g(DBSNP:rs2986017) increases a(CHEBI:"amyloid-beta")
pmid:22107728	g(DBSNP:rs4646953) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22107728	g(DBSNP:rs4646953) positiveCorrelation p(HGNC:APP, frag("672_713"))
pmid:22262751	g(DBSNP:rs6656401) association a(CHEBI:"amyloid-beta")
pmid:19734902	g(DBSNP:rs7866199) association g(HGNC:APBA1)
pmid:19734902	g(HGNC:APBA1) association g(DBSNP:rs1217338)
pmid:19734902	g(HGNC:APBA1) association g(DBSNP:rs7866199)
pmid:19734902	g(HGNC:APBA1) association path(MESHD:"Alzheimer Disease")
pmid:27050105	g(HGNC:APLP2) association p(HGNC:NFE2L1)
pmid:27050105	g(HGNC:APLP2) association p(HGNC:EGR1)
pmid:27050105	g(HGNC:APLP2) association p(HGNC:USF2)
pmid:9202294	g(HGNC:APOE) association path(MESHD:"Alzheimer Disease")
pmid:22323736	g(HGNC:APOE) increases a(CHEBI:"amyloid-beta")
pmid:19885299	g(HGNC:APOE) association bp(MESHPP:"Insulin Resistance")
pmid:19885299	g(HGNC:APOE) association path(MESHD:Hyperinsulinism)
pmid:19885299	g(HGNC:APOE) association path(MESHD:"Diabetes Mellitus")
pmid:19885299	g(HGNC:APOE) association path(MESHD:Dementia)
pmid:19885299	g(HGNC:APP) positiveCorrelation bp(MESHPP:"Oxidative Stress")
Online Resource:hsa05010	g(HGNC:APP) association path(MESHD:"Alzheimer Disease")
pmid:9202294	g(HGNC:APP) association path(MESHD:"Alzheimer Disease")
Online Resource:hsa05010	g(HGNC:APP) increases a(CHEBI:"amyloid-beta")
pmid:21062284	g(HGNC:APP) positiveCorrelation r(HGNC:PTBP1)
pmid:21062284	g(HGNC:APP) increases p(HGNC:APP)
pmid:18684319	g(HGNC:APP) increases r(HGNC:APP)
pmid:19245828	g(HGNC:APP, gmod(Me)) decreases p(HGNC:APP)
pmid:19245828	g(HGNC:APP, gmod(Me)) decreases p(HGNC:APP)
pmid:18628954	g(HGNC:APP, gmod(Me)) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22702962	g(HGNC:APP, var("c.275341G>C")) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:15177383	g(HGNC:APP, var("c.275341G>C")) increases p(HGNC:APP, frag("672_713"))
pmid:15177383	g(HGNC:APP, var("c.275341G>C")) increases a(CHEBI:"amyloid-beta")
pmid:15177383	g(HGNC:APP, var("c.717G>C")) increases p(HGNC:APP, frag("672_713"))
pmid:15177383	g(HGNC:APP, var("c.717G>C")) increases a(CHEBI:"amyloid-beta")
pmid:19519303	act(g(HGNC:BACE1)) increases act(p(HGNC:BACE1))
pmid:19245828	g(HGNC:BACE1, gmod(Me)) decreases p(HGNC:BACE1)
pmid:18628954	g(HGNC:BACE1, gmod(Me)) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:20580937	g(HGNC:CLTC) directlyIncreases bp(GOBP:"clathrin-dependent endocytosis")
pmid:20597865	g(HGNC:CTSD) association path(MESHD:"Alzheimer Disease")
pmid:20597865	g(HGNC:CTSD, var("c.224C>T")) positiveCorrelation p(HGNC:APP, frag("672_713"))
pmid:20580937	g(HGNC:DNM2) directlyIncreases bp(GOBP:"positive regulation of endocytosis")
pmid:20580937	g(HGNC:EPS15) directlyIncreases bp(GOBP:"positive regulation of endocytosis")
pmid:19734902	g(HGNC:FOXO3) association g(DBSNP:rs12212067)
pmid:22430674	g(HGNC:FRMD4A) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:17098871	g(HGNC:LRRTM3) increases p(HGNC:APP, frag("672_713"))
pmid:17098871	g(HGNC:LRRTM3) increases act(p(HGNC:BACE1), ma(pep))
pmid:19519303	act(g(HGNC:NGFR)) increases act(g(HGNC:BACE1))
pmid:22236693	g(HGNC:NGFR) increases bp(GOBP:"apoptotic process")
pmid:22236693	g(HGNC:NGFR) negativeCorrelation bp(GOBP:cognition)
pmid:22236693	g(HGNC:NGFR) association path(MESHD:Dementia)
Online Resource:hsa05010	g(HGNC:PSEN1) increases a(CHEBI:"amyloid-beta")
pmid:17995932	g(HGNC:PSEN1) increases p(HGNC:APP, frag("672_713"))
Online Resource:hsa05010	g(HGNC:PSEN2) increases a(CHEBI:"amyloid-beta")
pmid:20580937	g(HGNC:RAB5A) directlyIncreases bp(GOBP:"positive regulation of endocytosis")
pmid:21785276	m(HGNC:"MIR101-1") increases rxn(reactants(p(HGNC:APP)), products(p(HGNC:APP, frag("672_713"))))
pmid:21172309	m(HGNC:"MIR101-1") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:21172309	m(HGNC:"MIR101-1") decreases p(HGNC:APP)
pmid:22178568	m(HGNC:"MIR124-1") association p(HGNC:BACE1)
pmid:22178568	m(HGNC:"MIR124-1") association a(CHEBI:"amyloid-beta")
pmid:22178568	m(HGNC:"MIR124-1") association bp(GOBP:"apoptotic process")
pmid:22733824	m(HGNC:"MIR153-1") negativeCorrelation r(HGNC:APP)
pmid:22733824	m(HGNC:"MIR153-1") negativeCorrelation r(HGNC:APLP2)
pmid:22733824	m(HGNC:"MIR153-1") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:21994399	m(HGNC:"MIR9-1") negativeCorrelation r(HGNC:SPTLC3)
pmid:21994399	m(HGNC:"MIR9-1") negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:21785276	m(HGNC:MIR106A) association p(HGNC:APP)
pmid:21785276	m(HGNC:MIR106A) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:18684319	m(HGNC:MIR106A) decreases r(HGNC:APP)
pmid:21785276	m(HGNC:MIR106B) negativeCorrelation path(ADO:"Late_Onset_Alzheimer_s_Disease")
pmid:18234899	m(HGNC:MIR107) negativeCorrelation p(HGNC:BACE1)
pmid:18234899	m(HGNC:MIR107) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:20489155	m(HGNC:MIR107) association path(MESHD:"Alzheimer Disease")
pmid:20489155	m(HGNC:MIR107) association r(HGNC:GRN)
pmid:23546882	m(HGNC:MIR144) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:21994399	m(HGNC:MIR181C) negativeCorrelation r(HGNC:SPTLC3)
pmid:21994399	m(HGNC:MIR181C) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:21785276	m(HGNC:MIR298) increases act(p(HGNC:BACE1), ma(pep))
pmid:21785276	m(HGNC:MIR328) increases act(p(HGNC:BACE1), ma(pep))
pmid:21785276	m(HGNC:MIR520C) association p(HGNC:APP)
pmid:18684319	m(HGNC:MIR520C) decreases r(HGNC:APP)
pmid:1346802	p(GFAM:"Glutamate ionotropic receptor NMDA type subunits") association a(CHEBI:"amyloid-beta")
pmid:21244351	p(GFAM:"Glutamate ionotropic receptor NMDA type subunits") increases a(CHEBI:"amyloid-beta")
pmid:21244351	act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")) association a(CHEBI:"amyloid-beta")
pmid:19909279	p(GFAM:"Glutamate ionotropic receptor NMDA type subunits") association bp(GOBP:"regulation of synaptic plasticity")
pmid: 22646481	act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")) association bp(GOBP:"regulation of synaptic plasticity")
pmid:18675468	act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")) directlyIncreases bp(GOBP:"calcium ion import")
pmid: 22646481	act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")) association p(HGNC:APP, frag("672_713"))
pmid: 22646481	act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")) association bp(GOBP:"learning or memory")
pmid: 22646481	act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")) association bp(GOBP:"learning or memory")
pmid: 22646481	act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")) association bp(GOBP:"long term synaptic depression")
pmid:20847424	act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")) increases a(CHEBI:"reactive oxygen species")
pmid:24587007	act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")) increases a(CHEBI:"reactive oxygen species")
pmid:20847424	act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")) decreases act(a(MESHCS:Mitochondria))
pmid:12372252	act(p(GFAM:"M10 matrix metallopeptidases")) regulates act(p(HGNC:APP, frag("672_713")))
pmid:15688347	p(HGNC:"HLA-DQB1") association p(HGNC:APP, frag("672_713"))
pmid:20704561	p(HGNC:ABCA2) increases deg(p(HGNC:APP))
pmid:20704561	p(HGNC:ABCA2) regulates p(HGNC:APP)
pmid:20704561	p(HGNC:ABCA2) association path(MESHD:"Alzheimer Disease")
pmid:23556446	p(HGNC:ABCB1) increases a(CHEBI:"amyloid-beta")
pmid:23181169	p(HGNC:ABCB1) decreases a(CHEBI:"amyloid-beta")
pmid:23181169	p(HGNC:ABCB1) association path(MESHD:"Alzheimer Disease")
pmid:21718295	p(HGNC:ABCB1) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:21718295	p(HGNC:ABCB1) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:23789959	p(HGNC:ABCB1) association bp(GO:"GO:0097242")
pmid:23067778	p(HGNC:ABCB1, var("p.Cys1236Thr")) increases a(CHEBI:"amyloid-beta")
pmid:23067778	p(HGNC:ABCB1, var("p.Cys3435Thr")) increases a(CHEBI:"amyloid-beta")
pmid:23067778	p(HGNC:ABCB1, var("p.Gly2677Thr")) increases a(CHEBI:"amyloid-beta")
pmid:22496686	p(HGNC:ABL1) association composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP))
pmid:19306298	act(p(HGNC:ABL1), ma(kin)) increases p(HGNC:APP, pmod(Ph))
pmid:19306298	act(p(HGNC:ABL1), ma(kin)) increases p(HGNC:APBB1, pmod(Ph))
pmid:16014719	act(p(HGNC:ABL1), ma(kin)) directlyIncreases p(HGNC:MAPT, pmod(Ph))
pmid:19519303	act(p(HGNC:ACE)) increases deg(a(CHEBI:"amyloid-beta"))
pmid:24987467	p(HGNC:ACE) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:17973905	p(HGNC:ACE) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:17973905	act(p(HGNC:ACE)) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:24987467	p(HGNC:ACE) increases deg(p(HGNC:APP, frag("672_713")))
pmid:24987467	p(HGNC:ACE) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:11604391	p(HGNC:ACE) increases deg(p(HGNC:APP, frag("672_713")))
pmid:11604391	p(HGNC:ACE) increases deg(p(HGNC:APP, frag("672_711")))
pmid:11604391	p(HGNC:ACE) decreases a(HBP:"amyloid-beta aggregates")
pmid:21034527	act(p(HGNC:ACTA2)) decreases bp(GOBP:"regulation of actin filament binding")
pmid:18675468	act(p(HGNC:ADAM10), ma(pep)) increases deg(p(HGNC:APP))
pmid:20847424	act(p(HGNC:ADAM10)) increases deg(p(HGNC:APP))
pmid:16624814	p(HGNC:ADAM10) positiveCorrelation deg(p(HGNC:APP))
pmid:20849853	p(HGNC:ADAM10) increases deg(p(HGNC:APP))
pmid:18675468	act(p(HGNC:ADAM10), ma(pep)) increases a(HBP:"sAPP-alpha")
pmid:16624814	p(HGNC:ADAM10) positiveCorrelation a(HBP:"sAPP-alpha")
pmid:22524398	p(HGNC:ADAM10) increases a(HBP:"sAPP-alpha")
pmid:21799757	act(p(HGNC:ADAM10)) increases a(HBP:"sAPP-alpha")
pmid:21246057	act(p(HGNC:ADAM10)) increases a(HBP:"sAPP-alpha")
pmid:21431475	p(HGNC:ADAM10) increases a(HBP:"sAPP-alpha")
pmid:20847424	act(p(HGNC:ADAM10)) increases a(CHEBI:"amyloid-beta")
pmid:20849853	p(HGNC:ADAM10) decreases a(CHEBI:"amyloid-beta")
pmid:19237574	act(p(HGNC:ADAM10), ma(pep)) directlyIncreases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:23546882	p(HGNC:ADAM10) decreases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:22434822	act(p(HGNC:ADAM10), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:20849853	p(HGNC:ADAM10) increases bp(GOBP:cognition)
pmid:21214928	act(p(HGNC:ADAM10), ma(pep)) decreases rxn(reactants(p(HGNC:APP)), products(p(HGNC:APP, frag("672_713"))))
pmid:21214928	act(p(HGNC:ADAM10), ma(pep)) decreases rxn(reactants(p(HGNC:APP)), products(p(HGNC:APP, frag("672_713"))))
pmid:21214928	act(p(HGNC:ADAM10), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(a(HBP:"sAPP-alpha")))
pmid:21214928	act(p(HGNC:ADAM10), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(a(HBP:"sAPP-alpha")))
pmid:21214928	act(p(HGNC:ADAM10), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(a(HBP:"sAPP-alpha")))
pmid:20655472	act(p(HGNC:ADAM10)) increases act(p(SFAM:"NOTCH Family"))
pmid:20655472	act(p(HGNC:ADAM10)) increases p(SFAM:"NOTCH Family")
pmid:20847424	act(p(HGNC:ADAM17)) increases deg(p(HGNC:APP))
pmid:20847424	act(p(HGNC:ADAM17)) increases a(CHEBI:"amyloid-beta")
pmid:18021299	act(p(HGNC:ADAM17), ma(pep)) decreases rxn(reactants(p(HGNC:APP)), products(p(HGNC:APP, frag("672_713"))))
pmid:20847424	act(p(HGNC:ADAM9)) increases deg(p(HGNC:APP))
pmid:20847424	act(p(HGNC:ADAM9)) increases a(CHEBI:"amyloid-beta")
pmid:22844264	act(p(HGNC:ALB)) decreases complex(a(CHEBI:"copper(2+)"), p(HGNC:APP, frag("672_713")))
pmid:22844264	act(p(HGNC:ALB)) decreases bp(GOBP:"stress response to copper ion")
pmid:16153637	p(HGNC:ALB) decreases bp(GOBP:"mitochondrial depolarization")
pmid:16153637	p(HGNC:ALB) decreases bp(GOBP:"apoptotic process")
pmid:16153637	p(HGNC:ALB) decreases a(CHEBI:"cyclopiazonic acid")
pmid:16153637	p(HGNC:ALB) decreases a(CHEBI:dotarizine)
pmid:16153637	p(HGNC:ALB) decreases a(CHEBI:"Flunarizine hydrochloride")
pmid:22718756	act(p(HGNC:ALB)) decreases bp(GOBP:"neurofibrillary tangle assembly")
pmid:24094411	p(HGNC:ALB) decreases a(CHEBI:"amyloid-beta")
pmid:22718756	p(HGNC:ALB) regulates a(CHEBI:"amyloid-beta")
pmid:21280074	p(HGNC:ALOX5) increases a(CHEBI:"amyloid-beta")
pmid:21280074	p(HGNC:ALOX5) association a(CHEBI:"amyloid-beta")
pmid:23727898	p(HGNC:ALOX5) increases complex(GOCC:"5-lipoxygenase complex")
pmid:23727898	p(HGNC:ALOX5) increases a(CHEBI:"leukotriene B4")
pmid:18678882	p(HGNC:ALOX5) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22787047	p(HGNC:APBA2, pmod(Ph)) association tloc(p(HGNC:APP), fromLoc(MESHCS:"trans-Golgi Network"), toLoc(MESHCS:Endosomes))
pmid:11070505	p(HGNC:APOA2) increases complex(p(HGNC:APOE), p(HGNC:APP, frag("672_713")))
pmid:15177383	p(HGNC:APOE, var("p.Arg132Ser")) increases p(HGNC:APP, frag("672_713"))
pmid:15177383	p(HGNC:APOE, var("p.Arg132Ser")) increases a(CHEBI:"amyloid-beta")
pmid:21769591	p(HGNC:APOE, var("p.Arg132Ser")) directlyDecreases act(p(HGNC:APOE))
pmid:19038340	act(p(HGNC:APP, frag("17_42"))) association path(MESHD:"Neurotoxicity Syndromes")
pmid:18781964	p(HGNC:APP, frag("1_16")) increases path(MESHD:"Alzheimer Disease")
pmid:18781964	p(HGNC:APP, frag("1_8")) increases path(MESHD:"Alzheimer Disease")
pmid:20363024	p(HGNC:APP, frag("20_29")) decreases complex(p(HGNC:APOE), p(HGNC:APP, frag("672_713")))
pmid:23164821	p(HGNC:APP, frag("25_35")) increases p(HGNC:DKK1)
pmid:26809093	p(HGNC:APP, frag("25_35")) increases p(HGNC:NEFH)
pmid:26809093	p(HGNC:APP, frag("25_35")) increases p(HGNC:MAP2)
pmid:24290604	p(HGNC:APP, frag("25_35")) increases p(HGNC:TLR4)
pmid:22523685	p(HGNC:APP, frag("49_*")) directlyDecreases tloc(p(HGNC:COX4I1), fromLoc(MESHCS:Cytoplasm), toLoc(GOCC:mitochondrion))
pmid:22523685	p(HGNC:APP, frag("49_*")) directlyDecreases tloc(p(HGNC:COX4I2), fromLoc(MESHCS:Cytoplasm), toLoc(GOCC:mitochondrion))
pmid:22523685	p(HGNC:APP, frag("49_*")) directlyDecreases tloc(p(HGNC:COX5B), fromLoc(MESHCS:Cytoplasm), toLoc(GOCC:mitochondrion))
pmid:22523685	p(HGNC:APP, frag("49_*")) negativeCorrelation complex(GOCC:"respiratory chain complex IV")
pmid:22523685	p(HGNC:APP, frag("49_*")) positiveCorrelation a(CHEBI:radical)
pmid:22523685	p(HGNC:APP, frag("50_*")) directlyDecreases tloc(p(HGNC:COX4I1), fromLoc(MESHCS:Cytoplasm), toLoc(GOCC:mitochondrion))
pmid:22523685	p(HGNC:APP, frag("50_*")) directlyDecreases tloc(p(HGNC:COX4I2), fromLoc(MESHCS:Cytoplasm), toLoc(GOCC:mitochondrion))
pmid:22523685	p(HGNC:APP, frag("50_*")) directlyDecreases tloc(p(HGNC:COX5B), fromLoc(MESHCS:Cytoplasm), toLoc(GOCC:mitochondrion))
pmid:22523685	p(HGNC:APP, frag("50_*")) negativeCorrelation complex(GOCC:"respiratory chain complex IV")
pmid:22523685	p(HGNC:APP, frag("50_*")) negativeCorrelation a(CHEBI:radical)
pmid:18781964	p(HGNC:APP, frag("9_16")) increases path(MESHD:"Alzheimer Disease")
pmid:22764079	p(HGNC:APP, pmod(Me)) increases path(MESHD:"Alzheimer Disease")
pmid:22110360	p(HGNC:APP, pmod(Ph)) increases a(CHEBI:"amyloid-beta")
pmid:18650430	p(HGNC:APP, pmod(Ph, Thr, 668)) decreases complex(p(HGNC:APBB1), p(HGNC:APP))
pmid:11517218	p(HGNC:APP, pmod(Ph, Thr, 668)) decreases complex(p(HGNC:APBB1), p(HGNC:APP))
pmid:18650430	p(HGNC:APP, pmod(Ph, Thr, 668)) increases act(p(HGNC:BACE1), ma(pep))
pmid:14557249	p(HGNC:APP, pmod(Ph, Thr, 668)) increases act(p(HGNC:BACE1), ma(pep))
pmid:18650430	p(HGNC:APP, pmod(Ph, Thr, 668)) increases act(complex(SCOMP:"gamma Secretase Complex"))
pmid:14557249	p(HGNC:APP, pmod(Ph, Thr, 668)) increases a(CHEBI:"amyloid-beta")
pmid:22156573	p(HGNC:APP, pmod(Ph, Thr, 668)) increases a(CHEBI:"amyloid-beta")
pmid:15178331	p(HGNC:APP, pmod(Ph, Thr, 668)) decreases deg(p(HGNC:APP))
pmid:21156028	p(HGNC:APP, pmod(Ph, Thr, 688)) increases deg(p(HGNC:APP))
pmid:22496686	p(HGNC:APP, pmod(Ph, Tyr)) increases complex(p(HGNC:APP), p(HGNC:SHC2))
pmid:22496686	p(HGNC:APP, pmod(Ph, Tyr)) association complex(p(HGNC:APP), p(HGNC:GRB2))
pmid:11877420	p(HGNC:APP, pmod(Ph, Tyr)) increases complex(p(HGNC:APP), p(HGNC:SHC1))
pmid:22496686	p(HGNC:APP, pmod(Ph, Tyr, 682)) increases complex(p(HGNC:APP), p(HGNC:SHC1))
pmid:22496686	p(HGNC:APP, pmod(Ph, Tyr, 682)) increases complex(p(HGNC:APP), p(HGNC:GRB2))
pmid:22496686	p(HGNC:APP, pmod(Ph, Tyr, 682)) association p(HGNC:SHC1)
pmid:22496686	p(HGNC:APP, pmod(Ph, Tyr, 682)) increases bp(GOBP:"neuron development")
pmid:22496686	p(HGNC:APP, pmod(Ph, Tyr, 682)) association p(HGNC:GRB2)
pmid:21849536	p(HGNC:APP, pmod(Ph, Tyr, 682)) increases complex(p(HGNC:APP), p(HGNC:NTRK1))
pmid:21849536	p(HGNC:APP, pmod(Ph, Tyr, 682)) regulates act(p(HGNC:NTRK1))
pmid:22399757	p(HGNC:APP, pmod(Ub)) increases deg(p(HGNC:APP))
pmid:22382662	p(HGNC:APP, pmod(Ub)) positiveCorrelation deg(p(HGNC:APP))
pmid:22382662	p(HGNC:APP, pmod(Ub)) decreases p(HGNC:APP, frag("672_713"))
pmid:15946122	p(HGNC:APP, pmod(Ub)) decreases p(HGNC:APP, frag("672_713"))
pmid:22382662	p(HGNC:APP, pmod(Ub)) increases deg(a(CHEBI:"amyloid-beta"))
pmid:25948718	p(HGNC:APP, var("p.Ala713Thr")) increases path(MESHD:"Alzheimer Disease")
pmid:21903077	p(HGNC:APP, var("p.Asn10Tyr")) increases p(HGNC:APP, frag("672_713"))
pmid:21903077	p(HGNC:APP, var("p.Asn10Tyr")) increases path(MESHD:"Alzheimer Disease")
pmid:18570439	p(HGNC:APP, var("p.Asn596Leu")) increases a(CHEBI:"amyloid-beta")
pmid:22558227	p(HGNC:APP, var("p.Asp7His")) increases complex(a(CHEBI:"copper(2+)"), a(CHEBI:"zinc(2+)"), p(HGNC:APP, frag("672_711")))
pmid:21034535	p(HGNC:APP, var("p.Lys595Asn")) increases act(p(HGNC:BACE1), ma(pep))
pmid:21034535	p(HGNC:APP, var("p.Lys595Asn")) increases a(CHEBI:"amyloid-beta")
pmid:18570439	p(HGNC:APP, var("p.Lys595Met")) increases a(CHEBI:"amyloid-beta")
pmid:22514144	p(HGNC:APP, var("p.Lys687Asn")) association tloc(a(CHEBI:"amyloid-beta"), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:22514144	p(HGNC:APP, var("p.Lys687Asn")) increases a(CHEBI:"amyloid-beta")
pmid:21034535	p(HGNC:APP, var("p.Met596Leu")) increases act(p(HGNC:BACE1), ma(pep))
pmid:14557245	p(HGNC:APP, var("p.Val642Ile")) increases p(HGNC:NAE1)
pmid:22702962	p(HGNC:APP, var("p.Val717Leu")) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:17050537	p(HGNC:APPBP2) increases a(CHEBI:"amyloid-beta")
pmid:17050537	p(HGNC:APPBP2) increases deg(p(HGNC:APP))
pmid:22122372	p(HGNC:APPBP2) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:18509662	p(HGNC:AQP1) association bp(GOBP:"water homeostasis")
pmid:22115781	act(p(HGNC:ATF4)) increases p(HGNC:PSEN1)
pmid:20097758	p(HGNC:ATXN1) association act(p(HGNC:BACE1), ma(pep))
pmid:20097758	p(HGNC:ATXN1) association path(MESHD:"Alzheimer Disease")
pmid:20139999	p(HGNC:ATXN1) decreases p(HGNC:APP, frag("672_713"))
pmid:20139999	p(HGNC:ATXN1) negativeCorrelation p(HGNC:APP, frag("672_711"))
pmid:15466887	p(HGNC:BACE1, pmod(Ph)) association complex(p(HGNC:BACE1), p(HGNC:GGA1))
pmid:15232608	act(p(HGNC:BACE2), ma(pep)) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:20385830	act(p(HGNC:BACE2), ma(cat)) increases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:17428983	tloc(p(HGNC:BACE2), fromLoc(MESHCS:"Cell Surface Extensions"), toLoc(MESHCS:Endosomes)) increases a(CHEBI:"amyloid-beta")
pmid:10931940	act(p(HGNC:BACE2), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:12052539	act(p(HGNC:BACE2), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:15473697	act(p(HGNC:BACE2), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:BACE2) increases a(CHEBI:"amyloid-beta")
pmid:12052539	p(HGNC:BACE2) association path(MESHD:"Down Syndrome")
pmid:15473697	act(p(HGNC:BACE2), ma(pep)) directlyIncreases deg(p(HGNC:APP))
pmid:14744432	p(HGNC:BAD) association p(HGNC:TP53)
pmid:19885299	act(p(HGNC:BAD)) increases bp(GOBP:"apoptotic process")
pmid:11226677	p(HGNC:BCL2L1) decreases a(CHEBI:"amyloid-beta")
pmid:11226677	p(HGNC:BCL2L1) decreases bp(GOBP:"apoptotic process")
pmid:11592846	p(HGNC:BCL2L1) decreases bp(GOBP:"apoptotic process")
pmid:11226677	p(HGNC:BCL2L1) decreases bp(MESHPP:"Oxidative Stress")
pmid:17251431	p(HGNC:BCL2L11) association a(CHEBI:"amyloid-beta")
pmid:22212405	act(p(HGNC:BDNF)) association bp(GOBP:"axonal transport")
pmid:19499146	deg(p(HGNC:BID)) increases tloc(p(HGNC:CYCS), fromLoc(MESH:D008928), toLoc(MESHCS:Cytosol))
pmid:19499146	deg(p(HGNC:BID)) increases act(p(HGNC:BID))
pmid:10973933	p(HGNC:BLMH) increases a(CHEBI:"amyloid-beta")
pmid:10363952	p(HGNC:BLMH) increases bp(MESHPP:"Oxidative Stress")
pmid:10363952	p(HGNC:BLMH) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:20847424	p(HGNC:CACNG1) association a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:CACNG1) increases bp(GOBP:"positive regulation of synaptic plasticity")
pmid:20847424	p(HGNC:CACNG2) association a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:CACNG2) increases bp(GOBP:"positive regulation of synaptic plasticity")
pmid:20847424	p(HGNC:CACNG3) association a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:CACNG3) increases bp(GOBP:"positive regulation of synaptic plasticity")
pmid:20847424	p(HGNC:CACNG4) association a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:CACNG4) increases bp(GOBP:"positive regulation of synaptic plasticity")
pmid:20847424	p(HGNC:CACNG5) association a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:CACNG5) increases bp(GOBP:"positive regulation of synaptic plasticity")
pmid:20847424	p(HGNC:CACNG6) association a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:CACNG6) increases bp(GOBP:"positive regulation of synaptic plasticity")
pmid:20847424	p(HGNC:CACNG7) association a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:CACNG7) increases bp(GOBP:"positive regulation of synaptic plasticity")
pmid:20847424	p(HGNC:CACNG8) association a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:CACNG8) increases bp(GOBP:"positive regulation of synaptic plasticity")
pmid:19419557	p(HGNC:CALHM1, var("p.Pro86Leu")) increases a(CHEBI:"amyloid-beta")
pmid:25999473	p(HGNC:CALHM1) increases tloc(p(HGNC:IDE), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:20595388	p(HGNC:CAPN2) association path(DO:neuropathy)
pmid:20595388	p(HGNC:CAPN2) increases p(HGNC:BACE1)
pmid:20595388	p(HGNC:CAPN2) increases a(CHEBI:"amyloid-beta")
pmid:19499146	p(HGNC:CASP1) increases bp(GOBP:"inflammatory response")
pmid:24357806	p(HGNC:CASP1) increases p(HGNC:IL1B)
pmid:24357806	p(HGNC:CASP1) increases a(CHEBI:"reactive oxygen species")
pmid:10662829	act(p(HGNC:CASP2), ma(pep)) increases bp(GOBP:"neuron apoptotic process")
pmid:10911620	p(HGNC:CASP3) increases deg(p(HGNC:APP))
pmid:15178331	p(HGNC:CASP3) increases deg(p(HGNC:APP))
pmid:16496165	p(HGNC:CASP3) increases p(HGNC:MAPT, frag("?"))
pmid:19001528	act(p(HGNC:CASP3), ma(pep)) increases p(HGNC:MAPT, frag("?"))
pmid:11162250	act(p(HGNC:CASP3), ma(pep)) increases p(HGNC:MAPT, frag("?"))
pmid:10899937	act(p(HGNC:CASP3), ma(pep)) increases p(HGNC:MAPT, frag("?"))
pmid:15232608	act(p(HGNC:CASP4), ma(pep)) increases p(HGNC:MAPT, frag("?"))
pmid:10409650	p(HGNC:CASP6) increases deg(p(HGNC:APP))
pmid:10438520	p(HGNC:CASP6) increases deg(p(HGNC:APP))
pmid:15356202	act(p(HGNC:CASP6), ma(pep)) increases p(HGNC:MAPT, frag("?"))
pmid:16887805	act(p(HGNC:CASP9)) increases a(CHEBI:"amyloid-beta")
pmid:19499146	act(p(HGNC:CASP9)) increases bp(GOBP:"apoptotic process")
pmid:24948534	tloc(p(HGNC:CASR), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space")) association p(HGNC:APP, frag("672_713"))
pmid:24948534	p(HGNC:CASR) association a(CHEBI:"nitric oxide")
pmid:20595388	p(HGNC:CAST) decreases a(CHEBI:"amyloid-beta")
pmid:20595388	p(HGNC:CAST) decreases p(HGNC:APP, frag("672_713"))
pmid:20595388	p(HGNC:CAST) decreases act(p(HGNC:BACE1))
pmid:20595388	p(HGNC:CAST) decreases p(HGNC:MAPT, pmod(Ph))
pmid:21755121	p(HGNC:CCL2) biomarkerFor path(MESHD:"Alzheimer Disease")
pmid:20205643	p(HGNC:CCL2) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:26836182	p(HGNC:CCL2) positiveCorrelation bp(HBP:neuroinflammation)
pmid:21755121	p(HGNC:CCL2) positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:19394434	p(HGNC:CCR2) increases a(CHEBI:"amyloid-beta")
pmid:19394434	p(HGNC:CCR2) decreases bp(GOBP:memory)
pmid:19394434	act(p(HGNC:CCR2)) increases act(a(MESH:D001253))
pmid:18835047	p(HGNC:CCR2) increases a(MESH:D017628)
pmid:19394434	p(HGNC:CCR5) decreases act(p(HGNC:CCR2))
pmid:19394434	p(HGNC:CCR5) decreases path(MESHD:"Alzheimer Disease")
pmid:12607822	act(p(HGNC:CKB), ma(kin)) increases bp(MESHPP:"Lipid Peroxidation")
pmid:22434822	p(HGNC:CLSTN1) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:22434822	p(HGNC:CLSTN1) decreases a(CHEBI:"amyloid-beta")
pmid:22434822	deg(p(HGNC:CLSTN1)) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:22434822	p(HGNC:CLSTN1) decreases a(CHEBI:"amyloid-beta")
pmid:22434822	p(HGNC:CLSTN1) association act(p(HGNC:APP), ma(tport))
pmid:19192245	act(p(HGNC:CLSTN1), ma(tport)) increases tloc(p(HGNC:APP), fromLoc(MESHCS:"trans-Golgi Network"), toLoc(MESHCS:Endosomes))
pmid:22523685	p(HGNC:COX4I1) increases complex(GOCC:"respiratory chain complex IV")
pmid:22523685	p(HGNC:COX4I2) increases complex(GOCC:"respiratory chain complex IV")
pmid:22523685	p(HGNC:COX5B) increases complex(GOCC:"respiratory chain complex IV")
pmid:17046756	p(HGNC:CRYAB) increases path(MESHD:"Neurotoxicity Syndromes")
pmid:22058016	p(HGNC:CTNNB1) decreases p(HGNC:BGLAP)
pmid:10967351	p(HGNC:CTNNB1) association path(MESHD:"Alzheimer Disease")
pmid:18494933	p(HGNC:CTNNB1) positiveCorrelation bp(GOBP:"Wnt signaling pathway")
pmid:20847424	p(HGNC:CTNNB1) negativeCorrelation act(p(HGNC:GSK3B))
pmid:18494933	p(HGNC:CTNNB1) negativeCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:19499146	p(HGNC:CTSB) increases bp(GOBP:"apoptotic process")
pmid:19499146	p(HGNC:CTSB) increases deg(p(HGNC:BID))
pmid:19499146	p(HGNC:CTSB) increases deg(p(HGNC:BID))
pmid:19499146	p(HGNC:CTSB) increases deg(a(CHEBI:"amyloid-beta polypeptide 42"))
pmid:21613740	act(p(HGNC:CTSB), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:18957217	p(HGNC:CTSB) decreases p(HGNC:APP, frag("672_713"))
pmid:19499146	p(HGNC:CTSE) increases deg(p(HGNC:APP))
pmid:19499146	p(HGNC:CTSE) increases a(CHEBI:"amyloid-beta polypeptide 42")
pmid:19499146	p(HGNC:CTSL) increases bp(GOBP:"apoptotic process")
pmid:21755121	p(HGNC:CXCL10) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:21755121	p(HGNC:CXCL8) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:20568118	p(HGNC:DAB1) decreases complex(p(HGNC:APP), p(HGNC:LRP1))
pmid:19515914	p(HGNC:DAB1) association p(HGNC:APP)
pmid:18650430	p(HGNC:DAB1) association a(HBP:"YENPTY endocytosis motif (APP)")
pmid:22122372	p(HGNC:DAB1) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:19515914	p(HGNC:DAB1, pmod(Ph)) increases bp(GOBP:"regulation of neuron migration")
pmid:19515914	p(HGNC:DAB1, pmod(Ph)) increases bp(GOBP:"regulation of neuron migration")
pmid:22046282	p(HGNC:DDIT3) increases a(CHEBI:"amyloid-beta")
pmid:22046282	p(HGNC:DDIT3) decreases bp(GOBP:"iron ion homeostasis")
pmid:22046282	p(HGNC:DDIT3) increases bp(GOBP:"cell death")
pmid:22046282	p(HGNC:DDIT3) increases path(MESHD:Inflammation)
pmid:22046282	act(p(HGNC:DDIT3)) increases a(CHEBI:"reactive oxygen species")
pmid:23164821	p(HGNC:DKK1) decreases bp(GOBP:"Wnt signaling pathway")
pmid:23164821	p(HGNC:DKK1) decreases bp(GOBP:"Wnt signaling pathway")
pmid:26973255	p(HGNC:DKK1) decreases bp(GOBP:"Wnt signaling pathway")
pmid:24883305	p(HGNC:DKK1) decreases bp(GOBP:"Wnt signaling pathway")
pmid:23261660	p(HGNC:DKK1) decreases bp(GOBP:"Wnt signaling pathway")
pmid:23164821	p(HGNC:DKK1) decreases bp(GOBP:"Wnt signaling pathway")
pmid:23164821	p(HGNC:DKK1) increases bp(GOBP:"neuron apoptotic process")
pmid:23164821	p(HGNC:DKK1) increases bp(GOBP:"neuron death")
pmid:25384422	p(HGNC:DKK1) increases a(CHEBI:"amyloid-beta")
pmid:23164821	deg(p(HGNC:DKK1)) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:24883305	p(HGNC:DKK1) increases act(p(HGNC:APP, frag("672_713")))
pmid:18494933	p(HGNC:DKK1) positiveCorrelation p(HGNC:GSK3B, pmod(Ph))
pmid:23164821	p(HGNC:DKK1) positiveCorrelation p(HGNC:CLU)
pmid:23164821	p(HGNC:DKK1) increases p(HGNC:EGR1)
pmid:23164821	p(HGNC:DKK1) increases p(HGNC:FOS)
pmid:26880631	p(HGNC:DKK1) association path(MESHD:"Alzheimer Disease")
pmid:24883305	p(HGNC:DKK1) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:23261660	p(HGNC:DKK1) association path(MESHD:"Alzheimer Disease")
pmid:26880631	p(HGNC:DKK1) association path(MESHD:Osteoporosis)
pmid:26880631	p(HGNC:DKK1) association path(MESHD:Osteoporosis)
pmid:26809093	p(HGNC:DKK1) increases act(p(HGNC:MAP2), ma(GOBP:"protein polymerization"))
pmid:26809093	p(HGNC:DKK1) increases act(p(HGNC:NEFH), ma(GOBP:"protein polymerization"))
pmid:26809093	p(HGNC:DKK1) increases p(HGNC:MAPT, pmod(Ph))
pmid:26420483	p(HGNC:DKK1) association a(CHEBI:"(R)-ethosuximide")
pmid:25384422	p(HGNC:DKK1) increases p(HGNC:BACE1)
pmid:25384422	p(HGNC:DKK1) increases act(p(HGNC:BACE1))
pmid:23261660	p(HGNC:DKK1) increases path(MESHD:"Brain Ischemia")
pmid:23261660	p(HGNC:DKK1) positiveCorrelation bp(GOBP:"neuron development")
pmid:23261660	p(HGNC:DKK1) positiveCorrelation path(MESHD:"Neurodegenerative Diseases")
pmid:23261660	p(HGNC:DKK1) association path(MESHD:Stroke)
pmid:23261660	p(HGNC:DKK1) association path(MESHD:"Parkinson Disease")
pmid:23261660	p(HGNC:DKK1) association path(MESHD:"Epilepsy, Temporal Lobe")
pmid:19245828	p(HGNC:DNMT1) increases g(HGNC:BACE1, gmod(Me))
pmid:19245828	p(HGNC:DNMT1) increases g(HGNC:APP, gmod(Me))
pmid:19245828	p(HGNC:DNMT1) increases p(HGNC:SP1)
pmid:21156028	p(HGNC:DYRK1A) increases p(HGNC:APP, pmod(Ph, Thr, 688))
pmid:22110360	p(HGNC:DYRK1A) increases p(HGNC:APP, pmod(Ph))
pmid:22110360	p(HGNC:DYRK1A) increases p(HGNC:APP, pmod(Ph))
pmid:22110360	p(HGNC:DYRK1A) association p(HGNC:APP)
pmid:22110360	act(p(HGNC:DYRK1A)) increases bp(GOBP:"apoptotic process")
pmid:21156028	p(HGNC:DYRK1A) increases p(HGNC:MAPT, pmod(Ph, Thr, 212))
pmid:16242644	act(p(HGNC:DYRK1A), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 212))
pmid:22110360	p(HGNC:DYRK1A) increases p(HGNC:MAPT, pmod(Ph))
pmid:22110360	p(HGNC:DYRK1A) increases p(HGNC:MAPT, pmod(Ph))
pmid:18696092	act(p(HGNC:DYRK1A), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:22110360	p(HGNC:DYRK1A) association p(HGNC:MAPT)
pmid:21573099	act(p(HGNC:DYRK1A), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:20067632	p(HGNC:DYRK1A) increases p(HGNC:MAPT, pmod(Ph, Ser, 262))
pmid:20067632	p(HGNC:DYRK1A) increases p(HGNC:MAPT, pmod(Ph, Ser, 356))
pmid:21193044	p(HGNC:ECE2) increases act(p(HGNC:EDN1))
pmid:20634595	p(HGNC:EDN1) association path(MESHD:Inflammation)
pmid:16532272	act(p(HGNC:EIF2AK2)) increases bp(GOBP:"apoptotic process")
pmid:23092889	p(HGNC:EIF2AK2) regulates bp(GOBP:"neuron apoptotic process")
pmid:23092889	p(HGNC:EIF2AK2) increases bp(GOBP:"inflammatory response")
pmid:23092889	p(HGNC:EIF2AK2) association p(HGNC:MAPK1)
pmid:20067632	p(HGNC:EIF2AK2) increases p(HGNC:MAPT, pmod(Ph, Ser, 262))
pmid:20067632	p(HGNC:EIF2AK2) increases p(HGNC:MAPT, pmod(Ph, Ser, 356))
pmid:19499146	act(p(HGNC:FAS)) increases p(HGNC:CTSD)
pmid:22399757	p(HGNC:FBXL2) increases p(HGNC:APP, pmod(Ub))
pmid:10956649	p(HGNC:FURIN) increases p(HGNC:BACE1)
pmid:26147761	p(HGNC:GABRB2) increases bp(GOBP:"gamma-aminobutyric acid signaling pathway")
pmid:19909279	p(HGNC:GABRB2) association bp(GOBP:"regulation of synaptic plasticity")
pmid:23603201	p(HGNC:GCG) decreases p(HGNC:MAPT, pmod(Ph))
pmid:23603201	p(HGNC:GCG) decreases a(CHEBI:"amyloid-beta")
pmid:22718609	act(p(HGNC:GCG)) association p(SFAM:"GSK3 Family")
pmid:19573562	p(HGNC:GCG) decreases path(MESHD:"Neurodegenerative Diseases")
pmid:19573562	p(HGNC:GCG) increases bp(GOBP:"insulin secretion involved in cellular response to glucose stimulus")
pmid:19573562	p(HGNC:GCG) decreases a(CHEBI:glucose)
pmid:20035739	p(HGNC:GCG) regulates bp(GOBP:"insulin secretion")
pmid:20035739	p(HGNC:GCG) association bp(GOBP:"regulation of synaptic plasticity")
pmid:23603201	p(HGNC:GCG) negativeCorrelation p(HGNC:DPP4)
pmid:23603201	p(HGNC:GCG) decreases path(MESHD:"Diabetes Mellitus, Type 2")
pmid:17592527	act(p(HGNC:GCG)) decreases p(HGNC:APP)
pmid:17553422	p(HGNC:GGA3) decreases a(CHEBI:"amyloid-beta")
pmid:23296004	p(HGNC:GPR3) increases a(CHEBI:"amyloid-beta")
pmid:23296004	p(HGNC:GPR3) increases act(complex(SCOMP:"gamma Secretase Complex"), ma(pep))
pmid:20847424	p(HGNC:GRIA1) decreases a(GOCC:"excitatory synapse")
pmid:20847424	p(HGNC:GRIA2) decreases a(GOCC:"excitatory synapse")
pmid:20847424	p(HGNC:GRIA3) decreases a(GOCC:"excitatory synapse")
pmid:20847424	p(HGNC:GRIA4) decreases a(GOCC:"excitatory synapse")
pmid:20847424	act(p(HGNC:GRIN2A)) increases a(CHEBI:"amyloid-beta")
pmid:20847424	act(p(HGNC:GRIN2A)) increases a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:GRIN2A) decreases a(GOCC:"excitatory synapse")
pmid:22496686	p(HGNC:GRIN2A) association p(HGNC:LRP8)
pmid:20847424	act(p(HGNC:GRIN2C)) increases a(CHEBI:"amyloid-beta")
pmid:20847424	act(p(HGNC:GRIN2C)) increases a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:GRIN2C) decreases a(GOCC:"excitatory synapse")
pmid:20847424	act(p(HGNC:GRIN2D)) increases a(CHEBI:"amyloid-beta")
pmid:20847424	act(p(HGNC:GRIN2D)) increases a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:GRIN2D) decreases a(GOCC:"excitatory synapse")
pmid:20847424	act(p(HGNC:GRIN3A)) increases a(CHEBI:"amyloid-beta")
pmid:20847424	act(p(HGNC:GRIN3A)) increases a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:GRIN3A) decreases a(GOCC:"excitatory synapse")
pmid:20847424	act(p(HGNC:GRIN3B)) increases a(CHEBI:"amyloid-beta")
pmid:20847424	act(p(HGNC:GRIN3B)) increases a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:GRIN3B) decreases a(GOCC:"excitatory synapse")
pmid:20811458	p(HGNC:GSAP) increases a(CHEBI:"amyloid-beta")
pmid:20847424	act(p(HGNC:GSK3A)) increases a(CHEBI:"amyloid-beta")
pmid:16914869	p(HGNC:GSK3A) increases a(CHEBI:"amyloid-beta")
pmid:17902168	p(HGNC:GSK3A) increases p(HGNC:DPYSL2, pmod(Ph))
pmid:17902168	act(p(HGNC:GSK3A)) increases p(HGNC:DPYSL2, pmod(Ph))
pmid:17902168	act(p(HGNC:GSK3A)) positiveCorrelation p(HGNC:DPYSL2, pmod(Ph, Ser, 522))
pmid:7505567	act(p(HGNC:GSK3A)) increases p(HGNC:MAPT, frag("226_240"), pmod(Ph, Ser, 10))
pmid:7931292	act(p(HGNC:GSK3A)) increases p(HGNC:MAPT, pmod(Ph, Ser, 235))
pmid:7931292	act(p(HGNC:GSK3A)) increases p(HGNC:MAPT, pmod(Ph, Ser, 404))
pmid:19885299	p(HGNC:GSK3B, pmod(Ph, Ser, 9)) decreases act(p(HGNC:GSK3B))
pmid:19519303	p(HGNC:GSK3B, pmod(Ph, Ser, 9)) decreases act(p(HGNC:GSK3B))
pmid:15314261	p(HGNC:GSK3B, pmod(Ph, Ser, 9)) decreases act(p(HGNC:GSK3B))
pmid:18217188	p(HGNC:GSK3B, pmod(Ph, Ser, 9)) decreases act(p(HGNC:GSK3B))
pmid:20847424	p(HGNC:GSK3B, pmod(Ph, Ser, 9)) decreases act(p(HGNC:GSK3B))
pmid:15314261	p(HGNC:GSK3B, pmod(Ph, Ser, 9)) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:15773910	p(HGNC:GSK3B, pmod(Ph, Ser, 9)) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:20847424	p(HGNC:GSK3B, pmod(Ph, Ser, 9)) decreases p(HGNC:MAPT, pmod(Ph))
pmid:20847424	p(HGNC:GSK3B, pmod(Ph, Ser, 9)) decreases bp(GOBP:"neuron apoptotic process")
pmid:22184106	p(HGNC:GSK3B, pmod(Ph, Thr, 668)) increases deg(p(HGNC:APP))
pmid:19196431	p(HGNC:HIF1A) increases p(HGNC:BACE1)
pmid:10037734	p(HGNC:IL1A) increases p(HGNC:APP)
pmid:18715507	p(HGNC:IL1A) association bp(GOBP:"microglial cell activation involved in immune response")
pmid:22493750	p(HGNC:IL1A) association bp(GOBP:"inflammatory response")
pmid:10037734	p(HGNC:IL1A) increases bp(HBP:neuroinflammation)
pmid:22566778	p(HGNC:IL1A) positiveCorrelation bp(HBP:neuroinflammation)
pmid:22566778	p(HGNC:IL1A) increases bp(GOBP:"production of molecular mediator involved in inflammatory response")
pmid:20555131	p(HGNC:IL6) association bp(GOBP:"inflammatory response")
pmid:22493750	p(HGNC:IL6) association bp(GOBP:"inflammatory response")
pmid:22566778	p(HGNC:IL6) increases bp(GOBP:"production of molecular mediator involved in inflammatory response")
pmid:22566778	p(HGNC:IL6) positiveCorrelation bp(HBP:neuroinflammation)
pmid:25681350	p(HGNC:IL6) positiveCorrelation p(HGNC:CHI3L1)
pmid:25681350	p(HGNC:IL6) increases p(HGNC:CHI3L1)
pmid:23627755	p(HGNC:IL6) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:23627755	p(HGNC:IL6) positiveCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:20883690	act(p(HGNC:IL6)) increases bp(GOBP:gliogenesis)
pmid:24884485	p(HGNC:IL6) negativeCorrelation bp(GOBP:cognition)
pmid:19515914	p(HGNC:ITGB1) association p(HGNC:RELN)
pmid:19515914	p(HGNC:ITGB1) increases bp(GOBP:"regulation of neuron migration")
pmid:25698445	p(HGNC:ITGB1) decreases a(CHEBI:"amyloid-beta")
pmid:19515914	p(HGNC:ITGB1BP1) association p(HGNC:APP)
pmid:19515914	p(HGNC:ITGB1BP1) increases bp(GOBP:"neuron projection development")
pmid:17185504	p(HGNC:LDLR) increases a(CHEBI:"amyloid-beta")
pmid:22383525	p(HGNC:LDLR) increases deg(a(CHEBI:"amyloid-beta"))
pmid:22496686	p(HGNC:LDLR) association bp(GOBP:"cholesterol import")
pmid:22496686	p(HGNC:LDLR) association bp(GOBP:"neuron migration")
pmid:22496686	p(HGNC:LDLR) association bp(GOBP:"embryo development")
pmid:20049331	p(HGNC:LDLR) association bp(GOBP:"cholesterol metabolic process")
pmid:20232416	p(HGNC:LDLR) association bp(GOBP:"cholesterol homeostasis")
pmid:20005821	p(HGNC:LDLR) increases complex(p(HGNC:APOE), p(HGNC:LDLR))
pmid:20005821	p(HGNC:LDLR) decreases a(HBP:"amyloid-beta aggregates")
pmid:20005821	p(HGNC:LDLR) increases bp(GO:"GO:0097242")
pmid:22383525	p(HGNC:LDLR) regulates p(HGNC:APOE)
pmid:22383525	p(HGNC:LDLR) increases tloc(p(HGNC:APP, frag("672_713")), fromLoc(MESHCS:"COP-Coated Vesicles"), toLoc(MESHCS:Lysosomes))
pmid:20157255	p(HGNC:LEP) association a(CHEBI:"amyloid-beta")
pmid:20157255	p(HGNC:LEP) decreases a(CHEBI:"amyloid-beta")
pmid:19429119	p(HGNC:LEP) decreases a(CHEBI:"amyloid-beta")
pmid:19429119	p(HGNC:LEP) decreases act(p(HGNC:GSK3B))
pmid:20157255	p(HGNC:LEP) decreases p(HGNC:GSK3B)
pmid:19429119	p(HGNC:LEP) association bp(GOBP:"regulation of cAMP-dependent protein kinase activity")
pmid:19429119	p(HGNC:LEP) decreases p(HGNC:MAPT, pmod(Ph))
pmid:20157255	p(HGNC:LEP) association p(HGNC:MAPT, pmod(Ph))
pmid:20157255	p(HGNC:LEP) decreases p(HGNC:MAPT, pmod(Ph))
pmid:20157255	p(HGNC:LEP) association bp(MESHPP:"Cell Survival")
pmid:17314098	act(p(HGNC:MAPK1)) association p(HGNC:APP)
pmid:22156573	act(p(HGNC:MAPK1), ma(kin)) increases p(HGNC:APP, pmod(Ph, Thr, 668))
pmid:23092889	p(HGNC:MAPK1) association p(HGNC:EIF2AK2)
pmid:9202310	act(p(HGNC:MAPK1), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 181))
pmid:9202310	act(p(HGNC:MAPK1), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 205))
pmid:9202310	act(p(HGNC:MAPK1), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 202))
pmid:9202310	act(p(HGNC:MAPK1), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:9202310	act(p(HGNC:MAPK1), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 422))
pmid:24262633	act(p(HGNC:MAPK14)) association act(p(HGNC:NFE2L2))
pmid:24262633	act(p(HGNC:MAPK14)) association path(MESHD:Inflammation)
pmid:15658002	act(p(HGNC:MAPK14)) positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:11079778	act(p(HGNC:MAPK14), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:9202310	act(p(HGNC:MAPK14), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:15658002	act(p(HGNC:MAPK14), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:15977985	act(p(HGNC:MAPK14), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:11810404	p(HGNC:MAPK14) increases p(HGNC:MAPT, pmod(Ph))
pmid:15658002	act(p(HGNC:MAPK14)) positiveCorrelation path(MESHD:Tauopathies)
pmid:9202310	act(p(HGNC:MAPK14), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 181))
pmid:9202310	act(p(HGNC:MAPK14), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 205))
pmid:9202310	act(p(HGNC:MAPK14), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 202))
pmid:9202310	act(p(HGNC:MAPK14), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:9202310	act(p(HGNC:MAPK14), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 422))
pmid:15658002	act(p(HGNC:MAPK14), ma(kin)) increases p(HGNC:JUN, pmod(Ph))
pmid:15658002	act(p(HGNC:MAPK14), ma(kin)) increases p(HGNC:ATF2, pmod(Ph))
pmid:17314098	act(p(HGNC:MAPK3)) association p(HGNC:APP)
pmid:22249458	act(p(HGNC:MAPK3)) increases bp(GOBP:"response to oxidative stress")
pmid:22249458	act(p(HGNC:MAPK3)) increases p(HGNC:BACE1)
pmid:20660113	act(p(HGNC:MAPK3), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:12917434	act(p(HGNC:MAPK8), ma(kin)) increases p(HGNC:APP, pmod(Ph))
pmid:11803455	act(p(HGNC:MAPK8)) increases p(HGNC:MAPT, pmod(Ph))
pmid:15658002	act(p(HGNC:MAPK8)) positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:11803455	act(p(HGNC:MAPK8), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:17089132	act(p(HGNC:MAPK8), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:15977985	act(p(HGNC:MAPK8), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:11810404	p(HGNC:MAPK8) increases p(HGNC:MAPT, pmod(Ph))
pmid:19605645	act(p(HGNC:MAPK8), ma(kin)) increases p(HGNC:IRS1, pmod(Ph, Ser, 312))
pmid:19605645	act(p(HGNC:MAPK8), ma(kin)) increases deg(p(HGNC:IRS1))
pmid:18650430	p(HGNC:MAPK8) association a(HBP:"YENPTY endocytosis motif (APP)")
pmid:15658002	act(p(HGNC:MAPK8)) positiveCorrelation path(MESHD:Tauopathies)
pmid:22382662	p(HGNC:MAPT, pmod(Ph)) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22536436	p(HGNC:MAPT, pmod(Ph)) increases path(MESHD:"Alzheimer Disease")
pmid:22496686	p(HGNC:MAPT, pmod(Ph)) increases path(MESHD:"Alzheimer Disease")
pmid:18584921	p(HGNC:MAPT, pmod(Ph)) association path(MESHD:"Alzheimer Disease")
pmid:18675468	p(HGNC:MAPT, pmod(Ph)) increases path(MESHD:"Alzheimer Disease")
pmid:23362255	p(HGNC:MAPT, pmod(Ph)) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22720189	p(HGNC:MAPT, pmod(Ph)) increases path(MESHD:"Alzheimer Disease")
pmid:21666500	p(HGNC:MAPT, pmod(Ph)) association path(MESHD:"Alzheimer Disease")
pmid:20157255	p(HGNC:MAPT, pmod(Ph)) association path(MESHD:"Alzheimer Disease")
pmid:17954934	p(HGNC:MAPT, pmod(Ph)) association path(MESHD:"Alzheimer Disease")
pmid:14673212	p(HGNC:MAPT, pmod(Ph)) association path(MESHD:"Alzheimer Disease")
pmid:17120162	p(HGNC:MAPT, pmod(Ph)) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:9565682	p(HGNC:MAPT, pmod(Ph)) association path(MESHD:"Alzheimer Disease")
pmid:7533559	p(HGNC:MAPT, pmod(Ph)) association path(MESHD:"Alzheimer Disease")
pmid:8730715	p(HGNC:MAPT, pmod(Ph)) association path(MESHD:"Alzheimer Disease")
pmid:15658002	p(HGNC:MAPT, pmod(Ph)) association path(MESHD:"Alzheimer Disease")
pmid:18675468	p(HGNC:MAPT, pmod(Ph)) increases p(HGNC:APP, frag("672_713"))
pmid:18675468	p(HGNC:MAPT, pmod(Ph)) increases p(HGNC:APP, frag("672_711"))
pmid:12402041	p(HGNC:MAPT, pmod(Ph)) association a(CHEBI:"amyloid-beta")
pmid:19038340	p(HGNC:MAPT, pmod(Ph)) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:22122372	p(HGNC:MAPT, pmod(Ph)) increases bp(GOBP:"neuron apoptotic process")
pmid:21156028	p(HGNC:MAPT, pmod(Ph)) increases complex(GOCC:"neurofibrillary tangle")
pmid:19154537	p(HGNC:MAPT, pmod(Ph)) increases complex(GOCC:"neurofibrillary tangle")
pmid:16399206	p(HGNC:MAPT, pmod(Ph)) increases complex(GOCC:"neurofibrillary tangle")
pmid:18675468	p(HGNC:MAPT, pmod(Ph)) increases complex(GOCC:"neurofibrillary tangle")
pmid:14976144	p(HGNC:MAPT, pmod(Ph)) increases complex(GOCC:"neurofibrillary tangle")
pmid:23362255	p(HGNC:MAPT, pmod(Ph)) increases complex(GOCC:"neurofibrillary tangle")
pmid:16504486	p(HGNC:MAPT, pmod(Ph)) association complex(GOCC:"neurofibrillary tangle")
pmid:18494933	p(HGNC:MAPT, pmod(Ph)) increases complex(GOCC:"neurofibrillary tangle")
pmid:19519303	p(HGNC:MAPT, pmod(Ph)) association complex(p(HGNC:GSK3B), p(HGNC:PPP2CA))
pmid:21598254	p(HGNC:MAPT, pmod(Ph)) association bp(GOBP:"regulation of tau-protein kinase activity")
pmid:18494933	p(HGNC:MAPT, pmod(Ph)) negativeCorrelation p(HGNC:CTNNB1)
pmid:25024322	p(HGNC:MAPT, pmod(Ph)) positiveCorrelation p(HGNC:CHI3L1)
pmid:25865441	p(HGNC:MAPT, pmod(Ph)) positiveCorrelation p(HGNC:CHI3L1)
pmid:25865441	p(HGNC:MAPT, pmod(Ph)) positiveCorrelation p(HGNC:CHI3L1)
pmid:22536436	p(HGNC:MAPT, pmod(Ph)) association bp(MESHPP:"Insulin Resistance")
pmid:23627755	p(HGNC:MAPT, pmod(Ph)) association bp(MESHPP:"Insulin Resistance")
pmid:22536436	p(HGNC:MAPT, pmod(Ph)) association a(CHEBI:glucocorticoid)
pmid:22536436	p(HGNC:MAPT, pmod(Ph)) increases act(p(HGNC:CAPN1))
pmid:19519303	p(HGNC:MAPT, pmod(Ph)) association act(complex(p(HGNC:IGF1), p(HGNC:INSR)))
pmid:16399206	p(HGNC:MAPT, pmod(Ph)) association bp(GOBP:"negative regulation of insulin receptor signaling pathway")
pmid:23627755	p(HGNC:MAPT, pmod(Ph)) association path(MESHD:Hyperinsulinism)
pmid:21598254	p(HGNC:MAPT, pmod(Ph)) negativeCorrelation p(HGNC:AKT1)
pmid:21598254	p(HGNC:MAPT, pmod(Ph)) negativeCorrelation complex(GOCC:"phosphatidylinositol 3-kinase complex")
pmid:21598254	p(HGNC:MAPT, pmod(Ph)) negativeCorrelation p(HGNC:INS)
pmid:11956956	p(HGNC:MAPT, pmod(Ph)) association act(p(HGNC:INS))
pmid:19659459	p(HGNC:MAPT, pmod(Ph)) association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:19659459	p(HGNC:MAPT, pmod(Ph)) positiveCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:15658002	p(HGNC:MAPT, pmod(Ph)) positiveCorrelation act(p(HGNC:MAPK9))
pmid:15658002	p(HGNC:MAPT, pmod(Ph)) positiveCorrelation act(p(HGNC:MAPK8))
pmid:15658002	p(HGNC:MAPT, pmod(Ph)) positiveCorrelation act(p(HGNC:MAPK14))
pmid:21755121	p(HGNC:MAPT, pmod(Ph)) positiveCorrelation p(HGNC:CCL2)
pmid:20660113	p(HGNC:MAPT, pmod(Ph)) association path(MESHD:"Nerve Degeneration")
pmid:22222439	p(HGNC:MAPT, pmod(Ph)) association act(p(HGNC:CRH))
pmid:22496686	p(HGNC:MAPT, pmod(Ph)) decreases complex(a(GOCC:microtubule), p(HGNC:MAPT))
pmid:12668899	p(HGNC:MAPT, pmod(Ph)) association a(CHEBI:cholesterol)
pmid:18675468	p(HGNC:MAPT, pmod(Ph)) directlyDecreases bp(GOBP:"regulation of microtubule cytoskeleton organization")
pmid:19419557	p(HGNC:MAPT, pmod(Ph)) association bp(GOBP:"calcium-mediated signaling")
pmid:22536436	p(HGNC:MAPT, pmod(Ph)) regulates p(SFAM:"AKT Family", pmod(Ph))
pmid:19519303	p(HGNC:MAPT, pmod(Ph)) association act(p(HGNC:PPP2CA))
pmid:19519303	p(HGNC:MAPT, pmod(Ph)) association act(p(HGNC:GSK3B))
pmid:9089387	p(HGNC:MAPT, pmod(Ph)) increases act(p(HGNC:GSK3B))
pmid:22720189	p(HGNC:MAPT, pmod(Ph)) association m(HGNC:"MIR16-1")
pmid:22720189	p(HGNC:MAPT, pmod(Ph)) association m(HGNC:MIR132)
pmid:16504486	p(HGNC:MAPT, pmod(Ph)) decreases bp(GOBP:learning)
pmid:16504486	p(HGNC:MAPT, pmod(Ph)) decreases bp(GOBP:"regulation of synaptic plasticity")
pmid:16504486	p(HGNC:MAPT, pmod(Ph)) increases bp(GOBP:"negative regulation of microtubule depolymerization")
pmid:22078238	p(HGNC:MAPT, pmod(Ph)) negativeCorrelation p(HGNC:GAL)
pmid:16507903	p(HGNC:MAPT, pmod(Ph)) association p(HGNC:CDKN1A)
pmid:16507903	p(HGNC:MAPT, pmod(Ph)) association p(HGNC:CDKN1B)
pmid:21489990	p(HGNC:MAPT, pmod(Ph)) association p(HGNC:EGR1)
pmid:21666500	p(HGNC:MAPT, pmod(Ph)) association p(HGNC:RB1, pmod(Ph))
pmid:21707856	p(HGNC:MAPT, pmod(Ph)) association act(a(MESHC:"Protein Kinase C"))
pmid:24884485	p(HGNC:MAPT, pmod(Ph)) negativeCorrelation path(MESH:D060825)
pmid:17146290	p(HGNC:MAPT, pmod(Ph)) association p(HGNC:GRK2)
pmid:17146290	p(HGNC:MAPT, pmod(Ph)) association p(HGNC:GRK2)
pmid:20157255	p(HGNC:MAPT, pmod(Ph)) association p(HGNC:LEP)
pmid:14673212	p(HGNC:MAPT, pmod(Ph)) association path(MESHD:"Amyotrophic Lateral Sclerosis")
pmid:17360687	p(HGNC:MAPT, pmod(Ph)) decreases bp(GOBP:"apoptotic process")
pmid:17360687	p(HGNC:MAPT, pmod(Ph)) decreases p(HGNC:CTNNB1, pmod(Ph))
pmid:16410745	p(HGNC:MAPT, pmod(Ph)) decreases act(p(HGNC:F2), ma(pep))
pmid:15658002	p(HGNC:MAPT, pmod(Ph)) association path(MESHD:"Niemann-Pick Diseases")
pmid:15658002	p(HGNC:MAPT, pmod(Ph)) association path(DO:"progressive supranuclear palsy")
pmid:15658002	p(HGNC:MAPT, pmod(Ph)) association path(HBP:"Argyrophilic Grain Disease")
pmid:15658002	p(HGNC:MAPT, pmod(Ph)) association path(MESHD:"Parkinson Disease")
pmid:15686969	p(HGNC:MAPT, pmod(Ph)) association complex(p(HGNC:APBB1), p(HGNC:MAPT))
pmid:9512010	p(HGNC:MAPT, pmod(Ph)) association p(HGNC:APOE)
pmid:11264299	p(HGNC:MAPT, pmod(Ph)) decreases complex(p(HGNC:MAPT), p(HGNC:S100B))
pmid:22122372	p(HGNC:MAPT, pmod(Ph)) decreases bp(GOBP:memory)
pmid:8129042	p(HGNC:MAPT, pmod(Ph)) negativeCorrelation r(HGNC:MAPK1)
pmid:26402072	p(HGNC:MAPT, pmod(Ph)) association p(HGNC:TIMP1)
pmid:26402072	p(HGNC:MAPT, pmod(Ph)) association p(SFAM:"MMP Family")
pmid:19306298	p(HGNC:MME) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:18941241	p(HGNC:MME) positiveCorrelation act(p(HGNC:IL4))
pmid:19355846	p(HGNC:MME) decreases p(HGNC:APP, frag("672_713"))
pmid:7811262	act(p(HGNC:MMP2), ma(pep)) increases deg(p(HGNC:APP, frag("672_713")))
pmid:7811262	act(p(HGNC:MMP2), ma(pep)) increases deg(p(HGNC:APP, frag("672_711")))
pmid:22402435	act(p(HGNC:MMP2)) increases deg(a(CHEBI:"amyloid-beta"))
pmid:7811262	p(HGNC:MMP2) decreases a(CHEBI:"amyloid-beta")
pmid:7538720	p(HGNC:MMP2) increases path(MESHD:"Alzheimer Disease")
pmid:24519975	act(p(HGNC:MMP9)) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:22402435	act(p(HGNC:MMP9)) increases deg(a(CHEBI:"amyloid-beta"))
pmid:11327298	act(p(HGNC:MMP9), ma(pep)) increases a(CHEBI:"amyloid-beta")
pmid:17761425	p(HGNC:MMP9) increases a(HBP:"sAPP-alpha")
pmid:24918635	p(HGNC:MMP9) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:24918635	p(HGNC:MMP9) positiveCorrelation a(HBP:"amyloid-beta oligomers")
pmid:15882940	p(HGNC:MOK) increases p(HGNC:CSF1)
pmid:21209080	act(p(HGNC:MOK)) increases composite(p(HGNC:MAPK1), p(HGNC:MAPK8), p(HGNC:PIK3R2), p(HGNC:PIK3R5), p(HGNC:RAC1), p(HGNC:RASGRF1), p(HGNC:RHOA), p(HGNC:SKAP2))
pmid:14557245	p(HGNC:NAE1) increases bp(GOBP:"apoptotic process")
pmid:22267734	act(p(HGNC:NAT8)) increases p(HGNC:BACE1)
pmid:22267734	act(p(HGNC:NAT8B)) increases p(HGNC:BACE1)
pmid:22267734	act(p(HGNC:NAT8B)) increases a(CHEBI:"amyloid-beta")
pmid:19332646	act(p(HGNC:NFATC1)) increases p(HGNC:BACE1)
pmid:27050105	p(HGNC:NFE2L1) association g(HGNC:APLP2)
pmid:17223266	p(HGNC:NFKB1) increases a(CHEBI:"amyloid-beta")
pmid:17223266	p(HGNC:NFKB1) association act(p(HGNC:BACE1), ma(pep))
pmid:24290604	p(HGNC:NFKB1) association p(HGNC:APP)
pmid:18564425	act(p(HGNC:NFKB1), ma(tscript)) increases p(HGNC:APP)
pmid:24262633	p(HGNC:NFKB1) association act(p(HGNC:NFE2L2))
pmid:22654105	p(HGNC:NFKB1) decreases p(HGNC:APP, frag("672_713"))
pmid:21903077	p(HGNC:NOS2) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:21903077	p(HGNC:NOS2) increases a(CHEBI:"nitric oxide")
pmid:16472958	p(HGNC:NOS2) increases a(CHEBI:"nitric oxide")
pmid:16054114	p(HGNC:NOS2) increases a(CHEBI:"nitric oxide")
pmid:22227962	p(HGNC:NOS2) negativeCorrelation act(p(HGNC:IDE))
pmid:22227962	p(HGNC:NOS2) decreases p(HGNC:IDE)
pmid:22227962	p(HGNC:NOS2) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:22227962	p(HGNC:NOS2) negativeCorrelation deg(a(CHEBI:"amyloid-beta"))
pmid:9782132	p(HGNC:NOS2) decreases bp(GOBP:"regulation of viral process")
pmid:9782132	p(HGNC:NOS2) decreases bp(GOBP:"immune system process")
pmid:22227962	p(HGNC:NOS2) increases deg(p(HGNC:APP, frag("672_713")))
pmid:22227962	p(HGNC:NOS2) negativeCorrelation deg(p(HGNC:APP, frag("672_713")))
pmid:23237322	p(HGNC:NOTCH1) association p(HGNC:APP, frag("672_713"))
pmid:10366748	p(HGNC:NOTCH1) association bp(GOBP:neurogenesis)
pmid:22496686	p(HGNC:NUMB) association composite(p(HGNC:APLP1), p(HGNC:APLP2), p(HGNC:APP))
pmid:22122372	p(HGNC:NUMB) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:15671026	p(HGNC:PAWR) association act(p(HGNC:BACE1), ma(pep))
pmid:15671026	p(HGNC:PAWR) increases a(CHEBI:"amyloid-beta")
pmid:22539346	p(HGNC:PICALM) association bp(GOBP:"clathrin-dependent endocytosis")
pmid:22539346	p(HGNC:PICALM) regulates deg(p(HGNC:APP))
pmid:22539346	p(HGNC:PICALM) increases a(CHEBI:"amyloid-beta")
pmid:19276086	p(HGNC:PLD1) increases tloc(p(HGNC:PSEN1), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:10471309	p(HGNC:PLG) increases deg(p(HGNC:APP, frag("672_711")))
pmid:12754271	p(HGNC:PLG) increases deg(p(HGNC:APP, frag("672_713")))
pmid:15177383	p(HGNC:PSEN1, var("p.Glu280Ala")) increases p(HGNC:APP, frag("672_713"))
pmid:15177383	p(HGNC:PSEN1, var("p.Glu280Ala")) increases a(CHEBI:"amyloid-beta")
pmid:22710270	p(HGNC:PSEN1, var("p.Glu280Ala")) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22461631	p(HGNC:PSEN1, var("p.Glu280Ala")) decreases act(complex(SCOMP:"gamma Secretase Complex"))
pmid:15177383	p(HGNC:PSEN2, var("p.Asn141Ile")) increases p(HGNC:APP, frag("672_713"))
pmid:15177383	p(HGNC:PSEN2, var("p.Asn141Ile")) increases a(CHEBI:"amyloid-beta")
pmid:20157512	p(HGNC:PTGS1) increases path(MESHD:Inflammation)
pmid:20157512	act(p(HGNC:PTGS1)) increases path(MESHD:Inflammation)
pmid:10560656	p(HGNC:PTGS1) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:11194936	p(HGNC:PTGS1) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:10560656	p(HGNC:PTGS1) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:20157512	act(p(HGNC:PTGS1)) increases path(MESHD:"Nerve Degeneration")
pmid:11194936	p(HGNC:PTGS2) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:24455696	p(HGNC:PTGS2) increases bp(GOBP:"inflammatory response")
pmid:18570439	act(p(HGNC:QPCT), ma(pep)) increases p(HGNC:APP, frag("672_713"))
pmid:18570439	act(p(HGNC:QPCT), ma(pep)) increases p(HGNC:APP, frag("672_711"))
pmid:18570439	p(HGNC:QPCT) increases a(CHEBI:"amyloid-beta")
pmid:20127045	p(HGNC:RAB5A) association bp(GOBP:endocytosis)
pmid:21329555	p(HGNC:RELA) increases a(CHEBI:"amyloid-beta")
pmid:18688088	act(p(HGNC:RPS6KB1)) decreases bp(GOBP:"apoptotic process")
pmid:21289241	p(HGNC:RPS6KB1) association act(p(HGNC:IRS1))
pmid:16364302	act(p(HGNC:RPS6KB1), ma(kin)) directlyIncreases p(HGNC:MAPT, pmod(Ph, Ser, 262))
pmid:16364302	act(p(HGNC:RPS6KB1), ma(kin)) directlyIncreases p(HGNC:MAPT, pmod(Ph, Ser, 214))
pmid:16364302	act(p(HGNC:RPS6KB1), ma(kin)) directlyIncreases p(HGNC:MAPT, pmod(Ph, Thr, 212))
pmid:18852562	act(p(HGNC:RPS6KB1), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:24586443	p(HGNC:S100A9) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:23721320	p(HGNC:S100A9) increases path(MESHD:"Alzheimer Disease")
pmid:24240735	p(HGNC:S100A9) increases a(CHEBI:"amyloid-beta")
pmid:23223301	p(HGNC:S100A9) increases a(CHEBI:"amyloid-beta")
pmid:24262203	p(HGNC:S100A9) increases bp(HBP:neuroinflammation)
pmid:24262203	p(HGNC:S100A9) increases bp(GOBP:"microglial cell activation")
pmid:19499146	p(HGNC:SCAF11) increases bp(GOBP:"inflammatory response")
pmid:7670501	p(HGNC:SERPINA3) increases bp(GOBP:"amyloid fibril formation")
pmid:2190106	p(HGNC:SERPINA3) association p(HGNC:APP, frag("672_713"))
pmid:19222708	p(HGNC:SERPINI1) decreases act(p(HGNC:PLG))
pmid:19222708	p(HGNC:SERPINI1) increases a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:SLC25A31) association a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:SLC25A4) association a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:SLC25A5) association a(CHEBI:"amyloid-beta")
pmid:20847424	p(HGNC:SLC25A6) association a(CHEBI:"amyloid-beta")
pmid:22447723	p(HGNC:SLC39A1) association deg(p(HGNC:APP))
Online Resource:REACT_75925.2	p(HGNC:SNCA) association a(CHEBI:"amyloid-beta")
pmid:18297066	p(HGNC:SNCA) decreases act(a(MESH:D009474))
pmid:21985244	p(HGNC:SNCA) positiveCorrelation act(p(HGNC:GSK3B))
pmid:21985244	p(HGNC:SNCA) directlyIncreases p(HGNC:MAPT, pmod(Ph))
pmid:15910549	p(HGNC:SOD1) increases bp(GOBP:"response to oxidative stress")
pmid:15910549	p(HGNC:SOD1) increases bp(GOBP:"cellular response to oxidative stress")
pmid:20570967	p(HGNC:SOD1) increases p(HGNC:APP, frag("672_713"))
pmid:19519303	p(HGNC:SOD1) positiveCorrelation bp(MESHPP:Longevity)
pmid:16687508	act(p(HGNC:SOD2)) directlyDecreases path(MESHD:"Alzheimer Disease")
pmid:19245828	p(HGNC:SP1) increases a(CHEBI:"amyloid-beta")
pmid:17047360	p(HGNC:SPAG9) association p(HGNC:APP)
pmid:25681350	p(HGNC:STAT3) increases p(HGNC:CHI3L1)
pmid:21034527	act(p(HGNC:TAGLN)) decreases bp(GOBP:"regulation of actin filament binding")
pmid:21034527	act(p(HGNC:TAGLN)) decreases bp(GOBP:"regulation of mitochondrial membrane potential")
pmid:26402072	p(HGNC:TIMP1) association p(HGNC:APP, frag("672_713"))
pmid:26402072	p(HGNC:TIMP1) association p(HGNC:MAPT)
pmid:26402072	p(HGNC:TIMP1) association p(HGNC:MAPT, pmod(Ph))
pmid:26402072	p(HGNC:TIMP1) positiveCorrelation p(SFAM:"MMP Family")
pmid:24290604	p(HGNC:TLR4) association p(HGNC:APP)
pmid:19388207	act(p(HGNC:TLR4)) increases bp(GOBP:"inflammatory response")
pmid:24290604	p(HGNC:TLR4) association a(CHEBI:genistein)
pmid:18675254	p(HGNC:UBE2I) increases a(CHEBI:"amyloid-beta")
pmid:27050105	p(HGNC:USF2) association g(HGNC:APLP2)
pmid:23774792	p(MGI:Acat1) increases p(HGNC:APP)
pmid:23774792	p(MGI:Acat1) increases a(CHEBI:"amyloid-beta")
pmid:15673661	p(MGI:App) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:22434822	act(p(MGI:Bace1), ma(pep)) directlyIncreases rxn(reactants(p(MGI:App)), products(a(CHEBI:"amyloid-beta")))
pmid:21725719	p(MGI:Bace1) increases path(MESHD:"Alzheimer Disease")
pmid:20092570	p(MGI:Bace1) increases path(MESHD:"Alzheimer Disease")
pmid:21725719	p(MGI:Bace1) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:20092570	p(MGI:Bace1) positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:20092570	p(MGI:Bace1) increases a(CHEBI:"amyloid-beta")
pmid:20092570	p(MGI:Bace1) positiveCorrelation a(ADO:"presence_of_neuritic_plaque")
pmid:20092570	p(MGI:Bace1) orthologous p(HGNC:BACE1)
pmid:23040664	p(MGI:Ccl2) association path(MESHD:Amyloidosis)
pmid:24879954	act(p(MGI:Cysltr1)) increases a(CHEBI:"amyloid-beta")
pmid:24879954	p(MGI:Cysltr1) decreases p(MGI:Bcl2)
pmid:22047170	p(MGI:Ifng) increases p(MGI:Bace1)
pmid:22047170	p(MGI:Ifng) increases p(MGI:App)
pmid:22047170	p(MGI:Ifng) increases a(CHEBI:"amyloid-beta")
pmid:24587007	p(MGI:Ifng) increases a(CHEBI:"reactive oxygen species")
pmid:24874542	p(MGI:Il1b) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:24874542	p(MGI:Il1b) increases path(MESHD:"Plaque, Amyloid")
pmid:24874542	p(MGI:Il1b) increases path(MESHD:"Plaque, Amyloid")
pmid:23650073	p(MGI:Il1b) increases bp(GOBP:"inflammatory response")
pmid:24586443	p(MGI:S100a9) increases path(MESHD:"Plaque, Amyloid")
pmid:20098622	p(MGI:S100a9) increases bp(HBP:neuroinflammation)
pmid:15673661	p(MGI:Sp1) increases r(MGI:App)
pmid:22047170	p(MGI:Tnf) increases p(MGI:Bace1)
pmid:22047170	p(MGI:Tnf) increases p(MGI:App)
pmid:22047170	p(MGI:Tnf) increases a(CHEBI:"amyloid-beta")
pmid:22441986	p(MGI:Tnf) association bp(GOBP:"cytokine production involved in inflammatory response")
pmid:22441986	p(MGI:Tnf) increases bp(GOBP:"cytokine production involved in inflammatory response")
pmid:23650073	p(MGI:Tnf) increases bp(GOBP:"inflammatory response")
pmid:19918364	p(SFAM:"CREB Family") association p(HGNC:WWOX)
pmid:21945540	act(p(SFAM:"CREB Family")) positiveCorrelation r(HGNC:BDNF)
pmid:21945540	act(p(SFAM:"CREB Family")) negativeCorrelation act(p(MGI:Gsk3b))
pmid:19782073	act(p(SFAM:"GSK3 Family")) directlyIncreases p(HGNC:MAPT, pmod(Ph))
pmid:18852562	act(p(SFAM:"GSK3 Family")) increases p(HGNC:MAPT, pmod(Ph))
pmid:12428805	act(p(SFAM:"GSK3 Family")) increases p(HGNC:MAPT, pmod(Ph))
pmid:19038340	p(SFAM:"GSK3 Family") association path(MESHD:"Alzheimer Disease")
pmid:19038340	p(SFAM:"GSK3 Family") increases act(p(HGNC:APP, frag("17_42")))
pmid:21720686	p(SFAM:"GSK3 Family") regulates p(HGNC:LRP2, pmod(Ph))
pmid:22718609	act(p(SFAM:"GSK3 Family")) increases p(HGNC:GYS1, pmod(Ph))
pmid:22718609	p(SFAM:"GSK3 Family") association act(p(HGNC:GCG))
pmid:12428805	act(p(SFAM:"GSK3 Family")) regulates bp(GOBP:"axonal transport")
pmid:24874542	p(SFAM:"IL1 Family") association path(MESHD:"Plaque, Amyloid")
pmid:24874542	p(SFAM:"IL1 Family") association a(CHEBI:"3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonic acid)")
pmid:22496686	act(p(SFAM:"MAPK Erk1/2 Family")) association bp(GOBP:"neuron apoptotic process")
pmid:22496686	act(p(SFAM:"MAPK Erk1/2 Family")) increases bp(GOBP:"cell proliferation")
pmid:22496686	act(p(SFAM:"MAPK Erk1/2 Family")) increases bp(GOBP:"apoptotic process")
pmid:22496686	act(p(SFAM:"MAPK Erk1/2 Family")) association bp(GOBP:"apoptotic process")
pmid:22496686	act(p(SFAM:"MAPK Erk1/2 Family")) increases bp(GOBP:"apoptotic process")
pmid:22496686	p(SFAM:"MAPK Erk1/2 Family") association p(HGNC:APP)
pmid:19519303	act(p(SFAM:"MAPK Erk1/2 Family")) association a(CHEBI:"amyloid-beta")
pmid:22496686	act(p(SFAM:"MAPK Erk1/2 Family")) increases p(HGNC:MAPT, pmod(Ph))
pmid:22496686	act(p(SFAM:"MAPK Erk1/2 Family")) increases p(HGNC:MAPT, pmod(Ph))
pmid:11810404	p(SFAM:"MAPK Erk1/2 Family") increases p(HGNC:MAPT, pmod(Ph))
pmid:22496686	act(p(SFAM:"MAPK Erk1/2 Family")) increases p(HGNC:MAPT, pmod(Ph))
pmid:22496686	act(p(SFAM:"MAPK Erk1/2 Family")) increases p(HGNC:MAPT, pmod(Ph))
pmid:22496686	p(SFAM:"MAPK Erk1/2 Family", pmod(Ph)) association p(HGNC:APP)
pmid:17956317	act(p(SFAM:"MAPK JNK Family"), ma(kin)) decreases bp(GOBP:memory)
pmid:11567045	act(p(SFAM:"MAPK JNK Family")) increases a(CHEBI:"amyloid-beta")
pmid:26402072	p(SFAM:"MMP Family") association p(HGNC:APP, frag("672_713"))
pmid:23792694	p(SFAM:"MMP Family") increases deg(a(CHEBI:"amyloid-beta"))
pmid:24455696	p(SFAM:"MMP Family") increases bp(GOBP:"inflammatory response")
pmid:16822591	p(SFAM:"MMP Family") association path(MESHD:Dementia)
pmid:26402072	p(SFAM:"MMP Family") positiveCorrelation p(HGNC:TIMP1)
pmid:26402072	p(SFAM:"MMP Family") association p(HGNC:MAPT)
pmid:26402072	p(SFAM:"MMP Family") association p(HGNC:MAPT, pmod(Ph))
pmid:22367557	act(p(SFAM:"PRKA Family"), ma(kin)) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:22367557	p(SFAM:"PRKA Family") association path(MESHD:"Alzheimer Disease")
pmid:22367557	act(p(SFAM:"PRKA Family"), ma(kin)) increases a(CHEBI:"amyloid-beta")
pmid:22367557	act(p(SFAM:"PRKA Family"), ma(kin)) increases a(CHEBI:"amyloid-beta")
pmid:22367557	act(p(SFAM:"PRKA Family"), ma(kin)) decreases bp(GOBP:"TOR signaling")
pmid:22367557	act(p(SFAM:"PRKA Family"), ma(kin)) increases act(a(MESHCS:Lysosomes))
pmid:22367557	p(SFAM:"PRKA Family") regulates bp(GOBP:"regulation of energy homeostasis")
pmid:22367557	p(SFAM:"PRKA Family") regulates bp(GOBP:"glucose metabolic process")
pmid:22367557	p(SFAM:"PRKA Family") regulates bp(GOBP:"lipid metabolic process")
pmid:22367557	act(p(SFAM:"PRKA Family"), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:22367557	act(p(SFAM:"PRKA Family"), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:19237574	act(p(SFAM:"PRKAA Family")) increases a(CHEBI:"amyloid-beta")
pmid:21785276	path(ADO:"Late_Onset_Alzheimer_s_Disease") negativeCorrelation m(HGNC:MIR106B)
pmid:21156028	path(DO:amyloidosis) increases bp(GOBP:"neuron death")
pmid:20595388	path(DO:neuropathy) association p(HGNC:CAPN2)
pmid:22355794	path(MESH:D065852) association p(HGNC:APP)
pmid:26996954	path(MESHD:"Amyloid Neuropathies") association g(DBSNP:rs3824968)
pmid:24332564	path(MESHD:"Cerebral Amyloid Angiopathy") association composite(a(CHEBI:"amyloid-beta"), p(HGNC:NOS3), p(HGNC:PIN1))
pmid:24694234	path(MESHD:"Cognitive Dysfunction") association a(MESH:D001253)
pmid:22890100	path(MESHD:"Cognitive Dysfunction") positiveCorrelation p(HGNC:CHI3L1)
pmid:22890100	path(MESHD:"Cognitive Dysfunction") positiveCorrelation p(HGNC:CHI3L1)
pmid:24694234	path(MESHD:"Cognitive Dysfunction") association p(HGNC:RARRES3)
pmid:22496686	path(MESHD:"Down Syndrome") association p(HGNC:APP)
pmid:12052539	path(MESHD:"Down Syndrome") association p(HGNC:BACE2)
pmid:22496686	path(MESHD:"Down Syndrome") association p(HGNC:PSEN1)
Online Resource:REACT_75925.2	path(MESHD:"Huntington Disease") association path(MESHD:Amyloidosis)
pmid:22512552	path(MESHD:"Huntington Disease") positiveCorrelation a(CHEBI:"nitric oxide")
pmid:19076431	path(MESHD:"Huntington Disease") association bp(GOBP:"cell death")
pmid:17121991	path(MESHD:"Hypoxia, Brain") increases a(CHEBI:"amyloid-beta")
pmid:15232608	path(MESHD:"Neurogenic Inflammation") association bp(GOBP:"inflammatory response")
pmid:22493750	path(MESHD:"Neurogenic Inflammation") isA bp(GOBP:"inflammatory response")
pmid:22277195	path(MESHD:"Neurogenic Inflammation") decreases bp(GOBP:cognition)
pmid:22493750	path(MESHD:"Neurogenic Inflammation") increases path(MESHD:"Alzheimer Disease")
pmid:19038340	path(MESHD:"Neurotoxicity Syndromes") association act(p(HGNC:APP, frag("17_42")))
Online Resource:REACT_75925.2	path(MESHD:"Parkinson Disease") association path(MESHD:Amyloidosis)
pmid:23261660	path(MESHD:"Parkinson Disease") association p(HGNC:DKK1)
pmid:24262633	path(MESHD:"Parkinson Disease") association act(p(HGNC:NFE2L2))
pmid:24262633	path(MESHD:"Parkinson Disease") negativeCorrelation act(p(HGNC:NFE2L2))
pmid:18554520	path(MESHD:"Parkinson Disease") association path(MESHD:Inflammation)
pmid:24863743	path(MESHD:"Parkinson Disease") positiveCorrelation bp(HBP:neuroinflammation)
pmid:19076431	path(MESHD:"Parkinson Disease") association bp(GOBP:"cell death")
pmid:15658002	path(MESHD:"Parkinson Disease") association p(HGNC:MAPT, pmod(Ph))
pmid:24874542	path(MESHD:"Plaque, Amyloid") association p(SFAM:"IL1 Family")
pmid:24874542	path(MESHD:"Plaque, Amyloid") association a(CHEBI:"3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonic acid)")
Online Resource:REACT_75925.2	path(MESHD:Amyloidosis) association path(MESHD:"Alzheimer Disease")
Online Resource:REACT_75925.2	path(MESHD:Amyloidosis) association path(MESHD:"Parkinson Disease")
Online Resource:REACT_75925.2	path(MESHD:Amyloidosis) association path(MESHD:"Huntington Disease")
pmid:23040664	path(MESHD:Amyloidosis) association p(MGI:Ccl2)
pmid:16687508	path(MESHD:Dementia) association path(MESHD:"Alzheimer Disease")
pmid:21321400	path(MESHD:Dementia) association path(MESHD:"Alzheimer Disease")
pmid:19885299	path(MESHD:Dementia) negativeCorrelation p(HGNC:INS)
pmid:19885299	path(MESHD:Dementia) negativeCorrelation p(HGNC:IGF1)
pmid:19885299	path(MESHD:Dementia) negativeCorrelation p(HGNC:IGF2)
pmid:19885299	path(MESHD:Dementia) association path(MESHD:"Diabetes Mellitus")
pmid:19885299	path(MESHD:Dementia) association g(HGNC:APOE)
pmid:22236693	path(MESHD:Dementia) association g(HGNC:NGFR)
pmid:21321400	path(MESHD:Dementia) association act(p(HGNC:HEXB))
pmid:21321400	path(MESHD:Dementia) association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:16822591	path(MESHD:Dementia) association p(SFAM:"MMP Family")
pmid:8287928	path(MESHD:Gliosis) decreases bp(GOBP:axonogenesis)
pmid:21143158	path(MESHD:Gliosis) association bp(GOBP:"cytokine production involved in inflammatory response")
pmid:21143158	path(MESHD:Gliosis) increases act(p(HGNC:TNFSF10))
pmid:18410513	path(MESHD:Hypercholesterolemia) association p(HGNC:APP)
pmid:12218642	path(MESHD:Hypercholesterolemia) increases path(MESHD:"Alzheimer Disease")
pmid:19519303	path(MESHD:Hyperinsulinism) association a(CHEBI:"amyloid-beta")
pmid:19885299	path(MESHD:Hyperinsulinism) association g(HGNC:APOE)
pmid:19519303	path(MESHD:Hyperinsulinism) association path(DO:"post-surgical hypoinsulinemia")
pmid:23627755	path(MESHD:Hyperinsulinism) association p(HGNC:MAPT, pmod(Ph))
pmid:24332564	path(MESHD:Hypertension) association composite(a(CHEBI:"amyloid-beta"), p(HGNC:NOS3), p(HGNC:PIN1))
pmid:12218642	path(MESHD:Hypertension) increases path(MESHD:"Alzheimer Disease")
pmid:23164821	path(MESHD:Tauopathies) positiveCorrelation bp(GOBP:"Wnt signaling pathway, planar cell polarity pathway")
pmid:15658002	path(MESHD:Tauopathies) positiveCorrelation act(p(HGNC:MAPK9))
pmid:15658002	path(MESHD:Tauopathies) positiveCorrelation act(p(HGNC:MAPK8))
pmid:15658002	path(MESHD:Tauopathies) positiveCorrelation act(p(HGNC:MAPK14))
pmid:24808823	path(MESHD:Tauopathies) positiveCorrelation p(MGI:Ttbk1)
pmid:21769591	r(DBSNP:rs11542041) translatedTo p(HGNC:APOE, var("p.Arg132Ser"))
pmid:22733824	r(HGNC:APLP2) negativeCorrelation m(HGNC:"MIR153-1")
pmid:22733824	r(HGNC:APP) negativeCorrelation m(HGNC:"MIR153-1")
pmid:22733824	r(HGNC:APP) increases p(HGNC:APP)
pmid:18684319	r(HGNC:APP) increases p(HGNC:APP)
pmid:19885299	r(HGNC:APP) association path(MESHD:Inflammation)
pmid:19885299	r(HGNC:APP) negativeCorrelation bp(GOBP:"insulin receptor signaling pathway")
pmid:19885299	r(HGNC:APP) negativeCorrelation bp(GOBP:"insulin-like growth factor receptor signaling pathway")
pmid:23167255	r(HGNC:LRP1) increases p(HGNC:LRP1)
pmid:21676498	r(HGNC:LRP1) positiveCorrelation r(HGNC:APOE)
pmid:19665999	r(HGNC:LRP1) association m(HGNC:MIR205)
pmid:21062284	r(HGNC:PTBP1) positiveCorrelation g(HGNC:APP)
pmid:21062284	r(HGNC:PTBP1) increases p(HGNC:PTBP1)
pmid:15673661	r(MGI:App) positiveCorrelation r(MGI:Sp1)
pmid:15673661	r(MGI:Sp1) positiveCorrelation r(MGI:App)
pmid:23546882	rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta"))) increases path(MESHD:"Alzheimer Disease")
pmid:10830966	rxn(reactants(p(HGNC:CDK5R1)), products(p(HBP:"CDK5R1 p25"))) increases act(p(HGNC:CDK5), ma(kin))
pmid:19419557	p(HBP:"CDK5R1 p25") increases act(p(HGNC:CDK5), ma(kin))
pmid:18997293	a(CHEBI:"(R)-flurbiprofen") decreases a(CHEBI:"hydrogen peroxide")
pmid:18997293	a(CHEBI:"(R)-flurbiprofen") decreases bp(GOBP:"neuron apoptotic process")
pmid:18450518	a(CHEBI:"(R)-flurbiprofen") decreases a(CHEBI:"amyloid-beta")
pmid:20170836	a(CHEBI:"(R)-flurbiprofen") decreases a(CHEBI:"amyloid-beta")
pmid:18450518	a(CHEBI:"(R)-flurbiprofen") causesNoChange bp(GOBP:"regulation of prostaglandin-endoperoxide synthase activity")
pmid:18450518	a(CHEBI:"(R)-flurbiprofen") causesNoChange path(MESHD:"Alzheimer Disease")
pmid:20170836	a(CHEBI:"(R)-flurbiprofen") causesNoChange path(MESHD:"Alzheimer Disease")
pmid:20009055	a(CHEBI:"(R)-flurbiprofen") causesNoChange path(MESHD:"Alzheimer Disease")
pmid:18450517	a(CHEBI:"(R)-flurbiprofen") causesNoChange path(MESHD:"Alzheimer Disease")
pmid:20170836	a(CHEBI:"(R)-flurbiprofen") decreases complex(SCOMP:"gamma Secretase Complex")
pmid:20170836	a(CHEBI:"(R)-flurbiprofen") positiveCorrelation bp(GOBP:cognition)
pmid:19542625	a(CHEBI:"(R)-flurbiprofen") causesNoChange p(HGNC:APP, frag("672_713"))
pmid:18997293	a(CHEBI:"(R)-flurbiprofen") decreases act(p(HGNC:APP, frag("672_713")))
pmid:17599166	a(CHEBI:"(R)-flurbiprofen") decreases p(HGNC:APP, frag("672_713"))
pmid:19542625	a(CHEBI:"(R)-flurbiprofen") causesNoChange a(MESH:D001812)
pmid:20009055	a(CHEBI:"(R)-flurbiprofen") increases path(MESHD:Dizziness)
pmid:18450517	a(CHEBI:"(R)-flurbiprofen") increases path(MESHD:Dizziness)
pmid:20009055	a(CHEBI:"(R)-flurbiprofen") increases path(MESHD:Anemia)
pmid:17599166	a(CHEBI:"(R)-flurbiprofen") increases path(MESHD:Anemia)
pmid:20009055	a(CHEBI:"(R)-flurbiprofen") increases path(MESHD:Infection)
pmid:22710916	a(CHEBI:"(R)-flurbiprofen") decreases rxn(reactants(p(HGNC:APP)), products(a(CHEBI:"amyloid-beta")))
pmid:22710916	a(CHEBI:"(R)-flurbiprofen") isA a(CHEBI:"gamma-secretase modulator")
pmid:18450517	a(CHEBI:"(R)-flurbiprofen") increases path(MESHD:Diarrhea)
pmid:18450517	a(CHEBI:"(R)-flurbiprofen") increases path(MESHD:Nausea)
pmid:18997293	a(CHEBI:"(R)-flurbiprofen") increases bp(GOBP:"nerve growth factor production")
pmid:18997293	a(CHEBI:"(R)-flurbiprofen") increases p(HGNC:NGF)
pmid:18997293	a(CHEBI:"(R)-flurbiprofen") increases p(HGNC:BDNF)
pmid:17599166	a(CHEBI:"(R)-flurbiprofen") increases a(MESHC:"amyloid beta-protein (1-38)")
pmid:17599166	a(CHEBI:"(R)-flurbiprofen") increases path(MESHD:Eosinophilia)
pmid:17599166	a(CHEBI:"(R)-flurbiprofen") increases path(MESHD:"Respiratory Tract Infections")
pmid:16153637	a(CHEBI:"Flunarizine hydrochloride") increases bp(GOBP:"apoptotic process")
pmid:16153637	a(CHEBI:"cyclopiazonic acid") increases bp(GOBP:"apoptotic process")
pmid:16469440	a(CHEBI:"kainic acid") increases p(MGI:Aifm1)
pmid:15314261	a(CHEBI:"lithium chloride") decreases bp(GOBP:"neuron death")
pmid:15314261	a(CHEBI:"lithium chloride") decreases p(HGNC:GSK3B)
pmid:22536436	a(CHEBI:"lithium chloride") increases p(SFAM:"AKT Family", pmod(Ph))
pmid:15314261	a(CHEBI:"lithium chloride") decreases p(HGNC:MAPT, pmod(Ph))
pmid:21246057	a(CHEBI:"protectin D1") decreases bp(GOBP:"apoptotic process")
pmid:21246057	a(CHEBI:"protectin D1") decreases tloc(p(HGNC:APP, frag("672_713")), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:21246057	a(CHEBI:"protectin D1") decreases p(HGNC:APP, frag("672_713"))
pmid:21431475	a(CHEBI:"protectin D1") decreases p(HGNC:APP, frag("672_713"))
pmid:21246057	a(CHEBI:"protectin D1") isA a(CHEBI:"docosahexaenoic acid")
pmid:21246057	a(CHEBI:"protectin D1") increases bp(MESHPP:Neuroprotection)
pmid:21246057	a(CHEBI:"protectin D1") decreases bp(GOBP:"inflammatory response")
pmid:21246057	a(CHEBI:"protectin D1") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:21246057	a(CHEBI:"protectin D1") decreases act(p(HGNC:BACE1))
pmid:21431475	a(CHEBI:"protectin D1") decreases p(HGNC:BACE1)
pmid:21246057	a(CHEBI:"protectin D1") increases act(p(HGNC:ADAM10))
pmid:21431475	a(CHEBI:"protectin D1") increases act(p(HGNC:ADAM10))
pmid:21246057	a(CHEBI:"protectin D1") increases a(HBP:"sAPP-alpha")
pmid:21246057	a(CHEBI:"protectin D1") increases a(HBP:"sAPP-alpha")
pmid:21431475	a(CHEBI:"protectin D1") increases a(HBP:"sAPP-alpha")
pmid:21978835	a(CHEBI:"quercetin 3-O-beta-D-galactopyranoside") decreases complex(p(HGNC:BAD), p(HGNC:BCL2L1))
pmid:21400612	a(CHEBI:"sulindac sulfide") increases p(HGNC:PARP1)
pmid:19596284	a(CHEBI:LY294002) decreases p(HGNC:BIRC3)
pmid:19596284	a(CHEBI:LY294002) decreases p(HGNC:BIRC2)
pmid:20885006	a(CHEBI:Riluzole) decreases bp(GOBP:"apoptotic process")
pmid:10067977	a(CHEBI:Riluzole) decreases bp(GOBP:"apoptotic process")
pmid:21857080	a(CHEBI:Riluzole) decreases bp(GOBP:"apoptotic process")
pmid:16303979	a(CHEBI:Riluzole) decreases act(p(HGNC:PRKCA))
pmid:18718604	a(CHEBI:Riluzole) decreases bp(GOBP:"lipid oxidation")
pmid:20885006	a(CHEBI:Riluzole) decreases bp(MESHPP:"Oxidative Stress")
pmid:18718604	a(CHEBI:Riluzole) decreases act(p(SFAM:"PRKC Family"))
pmid:18718604	a(CHEBI:Riluzole) decreases a(CHEBI:"arachidonic acid")
pmid:22235318	a(CHEBI:Salidroside) decreases a(CHEBI:"reactive oxygen species")
pmid:22235318	a(CHEBI:Salidroside) decreases bp(GOBP:"cell death")
pmid:18624760	a(CHEBI:acitretin) increases p(HGNC:PARP1)
pmid:19596284	a(CHEBI:acrolein) increases p(HGNC:BIRC3)
pmid:19596284	a(CHEBI:acrolein) increases p(HGNC:BIRC2)
pmid:19596284	a(CHEBI:acrolein) association p(HGNC:AIFM1)
pmid:16219905	a(CHEBI:curcumin) decreases r(HGNC:BIRC2)
pmid:26113788	a(CHEBI:curcumin) increases act(p(HGNC:PTPN11))
pmid:18340409	a(CHEBI:curcumin) increases p(RGD:Il2ra)
pmid:16153637	a(CHEBI:dotarizine) increases bp(GOBP:"apoptotic process")
pmid:19343037	a(CHEBI:homocysteine) decreases r(HGNC:BIRC2)
pmid:20436886	a(CHEBI:isotretinoin) decreases r(HGNC:AIFM1)
pmid:20436886	a(CHEBI:isotretinoin) decreases r(HGNC:CHI3L1)
pmid:20436886	a(CHEBI:isotretinoin) increases r(HGNC:LCK)
pmid:17486130	a(CHEBI:isotretinoin) decreases r(HGNC:MYCN)
pmid:12930891	a(CHEBI:minocycline) decreases p(HGNC:AIFM1)
pmid:20555131	a(CHEBI:minocycline) decreases bp(GOBP:"production of molecular mediator involved in inflammatory response")
pmid:20555131	a(CHEBI:minocycline) decreases p(HGNC:GFAP)
pmid:20555131	a(CHEBI:minocycline) decreases p(HGNC:TNF)
pmid:20555131	a(CHEBI:minocycline) decreases p(HGNC:IL6)
pmid:20555131	a(CHEBI:minocycline) increases p(HGNC:CXCL1)
pmid:20555131	a(CHEBI:minocycline) increases p(HGNC:CCL3)
pmid:20555131	a(CHEBI:minocycline) decreases a(CHEBI:"amyloid-beta")
pmid:19001528	a(CHEBI:minocycline) decreases p(HGNC:MAPT, frag("?"))
pmid:17869087	a(CHEBI:piceatannol) decreases a(CHEBI:"hydrogen peroxide")
pmid:17869087	a(CHEBI:piceatannol) decreases a(CHEBI:peroxynitrite)
pmid:17869087	a(CHEBI:piceatannol) increases p(HGNC:BCL2L1)
pmid:17869087	a(CHEBI:piceatannol) decreases act(p(HGNC:MAPK8))
pmid:17869087	a(CHEBI:piceatannol) decreases p(HGNC:MAPK8, pmod(Ph))
pmid:17869087	a(CHEBI:piceatannol) decreases a(CHEBI:"reactive oxygen species")
pmid:17869087	a(CHEBI:piceatannol) decreases a(CHEBI:"reactive nitrogen species")
pmid:19343037	a(CHEBI:simvastatin) increases r(HGNC:BIRC2)
pmid:22058016	a(CHEBI:simvastatin) increases p(HGNC:BGLAP)
pmid:16274305	a(CHEBI:simvastatin) increases r(HGNC:COL3A1)
pmid:16387846	a(CHEBI:simvastatin) association p(HGNC:IL2RA)
pmid:16387846	a(CHEBI:simvastatin) decreases p(HGNC:CD86)
pmid:22235318	a(CHEBI:streptozocin) increases a(CHEBI:"reactive oxygen species")
pmid:22235318	a(CHEBI:streptozocin) increases bp(GOBP:"cell death")
pmid:19634143	a(CHEBI:streptozocin) increases p(RGD:Aifm1)
pmid:19885299	a(CHEBI:streptozocin) increases path(MESHD:"Diabetes Mellitus, Experimental")
pmid:15566391	a(MESHC:"cinnamic aldehyde") decreases r(HGNC:BIRC2)
pmid:22235318	a(MESHC:Catalase) decreases a(CHEBI:"reactive oxygen species")
pmid:22235318	a(MESHC:Catalase) decreases bp(GOBP:"cell death")
pmid:19499146	a(MESHCS:Lysosomes) association bp(GOBP:"apoptotic process")
pmid:19499146	a(MESHCS:Lysosomes) association bp(GOBP:phagocytosis)
pmid:22367557	act(a(MESHCS:Lysosomes)) increases deg(p(HGNC:APP, frag("672_713")))
pmid:25570489	a(NIFT:"Ventricular expansion") association p(HGNC:ESR1)
pmid:25570489	a(NIFT:"Ventricular expansion") association p(HGNC:SORCS1)
pmid:19519303	bp(GOBP:"ERK1 and ERK2 cascade") increases bp(GOBP:"intrinsic apoptotic signaling pathway in response to oxidative stress")
pmid:19519303	bp(GOBP:"ERK1 and ERK2 cascade") association bp(MESHPP:"Neuronal Plasticity")
pmid:19519303	bp(GOBP:"ERK1 and ERK2 cascade") association bp(MESHPP:"Long-Term Potentiation")
pmid:19519303	bp(GOBP:"ERK1 and ERK2 cascade") increases p(HGNC:MAPT, pmod(Ph))
pmid:22496686	bp(GOBP:"Notch signaling pathway") association bp(GOBP:"apoptotic process")
pmid:22496686	bp(GOBP:"Notch signaling pathway") association bp(GOBP:"neuron death")
pmid:12639958	bp(GOBP:"Notch signaling pathway") positiveCorrelation p(HGNC:PSENEN)
pmid:22496686	bp(GOBP:"Notch signaling pathway") association bp(GOBP:"regulation of cell fate commitment")
pmid:22496686	bp(GOBP:"Notch signaling pathway") association bp(GOBP:"cell proliferation")
pmid:22496686	bp(GOBP:"Notch signaling pathway") association bp(GOBP:"cell differentiation")
pmid:10967351	bp(GOBP:"Notch signaling pathway") association p(HGNC:PSEN2)
pmid:10967351	bp(GOBP:"Notch signaling pathway") association p(HGNC:PSEN1)
pmid:10967351	bp(GOBP:"Notch signaling pathway") association bp(GOBP:"brain development")
PubMed Central:PMC3892805	bp(GOBP:"Notch signaling pathway") increases r(HGNC:HES2)
pmid:22496686	bp(GOBP:"cellular response to DNA damage stimulus") association complex(p(HGNC:APBB1), p(HGNC:APP))
pmid:16153637	bp(GOBP:"endoplasmic reticulum calcium ion homeostasis") decreases bp(GOBP:"mitochondrial depolarization")
pmid:16153637	bp(GOBP:"endoplasmic reticulum calcium ion homeostasis") decreases bp(GOBP:"apoptotic process")
pmid:22223749	bp(GOBP:"focal adhesion assembly") regulates bp(GOBP:"cell death")
pmid:19499146	bp(GOBP:"positive regulation of lysosomal membrane permeability") increases bp(GOBP:"apoptotic process")
pmid:19499146	bp(GOBP:"positive regulation of lysosomal membrane permeability") increases tloc(p(GFAM:Cathepsins), fromLoc(MESHCS:Lysosomes), toLoc(MESHCS:Cytosol))
pmid:19499146	bp(GOBP:"positive regulation of lysosomal membrane permeability") increases act(p(HGNC:BID))
pmid:20100581	bp(HP:Neurodegeneration) association p(HGNC:APP)
pmid:23791873	bp(MESH:D000066829) association deg(p(HGNC:CDKN1B))
pmid:19885299	bp(MESH:D000066829) positiveCorrelation bp(GOBP:"Wnt signaling pathway")
pmid:17308104	complex(a(CHEBI:"5-chloro-7-iodoquinolin-8-ol"), a(CHEBI:"copper(2+)")) decreases p(HGNC:AR)
pmid:17308104	complex(a(CHEBI:"5-chloro-7-iodoquinolin-8-ol"), a(CHEBI:"copper(2+)")) increases bp(GOBP:"apoptotic process")
pmid:21400612	complex(a(CHEBI:"GW 0742"), a(CHEBI:"sulindac sulfide")) increases p(HGNC:PARP1)
pmid:16243823	complex(a(CHEBI:curcumin), a(CHEBI:doxorubicin)) association r(HGNC:BIRC3)
pmid:19372569	complex(a(CHEBI:curcumin), a(CHEBI:thalidomide)) increases p(HGNC:PARP1)
pmid:22236693	complex(p(HGNC:APP, frag("672_713")), p(HGNC:NGFR)) increases bp(GOBP:"apoptotic process")
pmid:19499146	complex(p(HGNC:CASP8), p(HGNC:FADD), p(HGNC:PTPN13)) increases act(p(HGNC:CASP8))
pmid:19499146	complex(p(HGNC:CASP8), p(HGNC:FADD), p(HGNC:TRADD)) increases act(p(HGNC:CASP8))
pmid:26808775	complex(p(HGNC:TNFRSF12A), p(HGNC:TNFRSF25)) increases bp(GOBP:"apoptotic process")
pmid:19918364	p(GFAM:"NF-kappa B complex subunits") association bp(GOBP:"cell death")
pmid:19596284	p(HGNC:AIFM1) association a(CHEBI:acrolein)
pmid:21179406	p(HGNC:AIFM1) association a(CHEBI:"hydrogen peroxide")
pmid:15126337	p(HGNC:AIFM1) association a(CHEBI:"nitric oxide")
pmid:16617056	p(HGNC:BAK1) increases p(HGNC:AIFM1)
pmid:14744432	p(HGNC:BAX) association p(HGNC:TP53)
pmid:15525785	act(p(HGNC:BAX)) increases bp(GOBP:"apoptotic process")
pmid:22496686	p(HGNC:BCL2) decreases bp(GOBP:"apoptotic process")
pmid:11592846	p(HGNC:BCL2) decreases bp(GOBP:"apoptotic process")
pmid:11577002	p(HGNC:BCL2) increases p(HGNC:BIRC2)
pmid:22496686	p(HGNC:BCL2) association p(HGNC:PSEN1)
pmid:16507903	p(HGNC:CDKN1A) decreases bp(GOBP:"apoptotic process")
pmid:16507903	p(HGNC:CDKN1A) association bp(GOBP:"cell death")
pmid:16507903	p(HGNC:CDKN1A) association p(HGNC:MAPT, pmod(Ph))
pmid:23791873	deg(p(HGNC:CDKN1B)) association bp(MESH:D000066829)
pmid:16507903	p(HGNC:CDKN1B) association p(HGNC:MAPT, pmod(Ph))
pmid:15773910	p(HGNC:CDKN1B) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:21396986	act(p(HGNC:DHCR24)) decreases bp(GOBP:"apoptotic process")
pmid:21396986	p(HGNC:DHCR24) increases a(CHEBI:cholesterol)
pmid:21396986	p(HGNC:DHCR24) decreases p(HGNC:APP, frag("672_713"))
pmid:21396986	p(HGNC:DHCR24) association deg(p(HGNC:APP, frag("672_713")))
pmid:21396986	p(HGNC:DHCR24) increases act(a(CHEBI:estrogen))
pmid:22122372	p(HGNC:DPYSL2, pmod(Ph)) increases bp(GOBP:"neuron apoptotic process")
pmid:15676027	p(HGNC:DPYSL2, pmod(Ph)) positiveCorrelation act(p(HGNC:GSK3B))
pmid:25570489	p(HGNC:ESR1) association a(NIFT:"Ventricular expansion")
pmid:25570489	p(HGNC:ESR1) association a(NIFT:"Hippocampal atrophy")
pmid:11592846	p(HGNC:GDNF) increases p(HGNC:BCL2)
pmid:11592846	p(HGNC:GDNF) increases p(HGNC:BCL2L1)
pmid:11592846	p(HGNC:GDNF) decreases tloc(p(HGNC:BAX), fromLoc(MESHCS:Cytosol), toLoc(MESH:D008928))
pmid:11592846	p(HGNC:GDNF) decreases bp(GOBP:"apoptotic process")
pmid:11400916	p(HGNC:NDUFS1) decreases bp(GOBP:"apoptotic process")
pmid:11400916	p(HGNC:NDUFV2) decreases bp(GOBP:"apoptotic process")
pmid:22236693	p(HGNC:NTRK1) negativeCorrelation bp(GOBP:"apoptotic process")
pmid:22433871	p(HGNC:PAFAH2) increases deg(a(CHEBI:phospholipid))
pmid:22433871	p(HGNC:PAFAH2) decreases p(HGNC:TNF)
pmid:14580317	p(HGNC:PRKCD) increases bp(GOBP:"apoptotic signaling pathway")
pmid:24821282	p(HGNC:PTPA) decreases bp(GOBP:"apoptotic process")
pmid:24821282	p(HGNC:PTPA) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:22299660	act(p(HGNC:PTPA), ma(phos)) decreases p(HGNC:MAPT, pmod(Ph))
pmid:12435421	act(p(HGNC:PTPA), ma(phos)) decreases p(HGNC:MAPT, pmod(Ph))
pmid:17316167	p(HGNC:SPP1) association bp(GOBP:"apoptotic process")
pmid:17316167	p(HGNC:SPP1) association path(MESHD:Inflammation)
pmid:17316167	p(HGNC:SPP1) association bp(MESHPP:"Oxidative Stress")
pmid:24454492	p(HGNC:TRPV1) decreases bp(GOBP:"apoptotic process")
pmid:19918364	p(HGNC:WWOX) association p(SFAM:"CREB Family")
pmid:19918364	p(HGNC:WWOX) decreases p(SFAM:"CREB Family")
pmid:19918364	p(HGNC:WWOX) association bp(GOBP:"cell death")
pmid:19918364	p(HGNC:WWOX) increases bp(GOBP:"cell death")
pmid:19918364	p(HGNC:WWOX) association path(MESHD:"Wounds and Injuries")
pmid:21699726	p(MGI:Eif2ak2) increases bp(GOBP:"neuron death")
pmid:12548636	p(MGI:Hspd1) decreases bp(GOBP:"apoptotic process")
pmid:12065618	p(MGI:Pparg) increases bp(GOBP:"apoptotic process")
pmid:12065618	p(MGI:Pparg) increases p(MGI:Cdh2)
pmid:12548636	p(MGI:Vim) decreases bp(GOBP:"apoptotic process")
pmid:12548636	p(MGI:Vim, pmod(GO:"GO:0018158")) increases bp(GOBP:"apoptotic process")
pmid:18718604	p(RGD:Tnf) increases bp(GOBP:"apoptotic process")
pmid:23153928	p(SFAM:"CALM Family") decreases bp(GOBP:"apoptotic process")
pmid:18782350	p(SFAM:"CREB Family", pmod(Ph)) decreases bp(GOBP:"cell death")
pmid:22496686	tloc(p(SFAM:"NOTCH Family"), fromLoc(MESHCS:Cytoplasm), toLoc(MESHCS:"Cell Nucleus")) increases act(p(HGNC:RBPJL))
pmid:22496686	p(SFAM:"NOTCH Family") association composite(p(HGNC:PSEN1), p(HGNC:PSEN2))
pmid:20089128	p(SFAM:"NOTCH Family") association composite(p(HGNC:PSEN1), p(HGNC:PSEN2))
pmid:22496686	act(p(SFAM:"NOTCH Family")) increases bp(GOBP:"Notch signaling pathway")
pmid:20089128	act(p(SFAM:"NOTCH Family")) increases bp(GOBP:"Notch signaling pathway")
pmid:17316167	path(MESHD:"Neurodegenerative Diseases") association bp(GOBP:"apoptotic process")
pmid:23261660	path(MESHD:"Neurodegenerative Diseases") positiveCorrelation p(HGNC:DKK1)
pmid:17316167	path(MESHD:"Neurodegenerative Diseases") association path(MESHD:Inflammation)
pmid:15255951	path(MESHD:"Neurodegenerative Diseases") association bp(MESHPP:"Oxidative Stress")
pmid:23653222	path(MESHD:"Neurodegenerative Diseases") association bp(MESHPP:"Oxidative Stress")
pmid:17316167	path(MESHD:"Neurodegenerative Diseases") association bp(MESHPP:"Oxidative Stress")
pmid:16515557	path(MESHD:"Neurodegenerative Diseases") association p(HGNC:NOTCH2)
pmid:19076431	path(MESHD:"Neurodegenerative Diseases") association bp(GOBP:"cell death")
pmid:19918364	path(MESHD:"Wounds and Injuries") increases p(HGNC:WWOX)
pmid:19918364	path(MESHD:"Wounds and Injuries") association p(HGNC:WWOX)
pmid:24262633	path(MESHD:"Wounds and Injuries") association act(p(HGNC:NFE2L2))
pmid:21826169	r(HGNC:AIFM1) association a(CHEBI:estradiol)
pmid:16243823	r(HGNC:BIRC3) association complex(a(CHEBI:curcumin), a(CHEBI:doxorubicin))
pmid:22433871	r(HGNC:PAFAH2) increases p(HGNC:PAFAH2)
pmid:26420483	a(CHEBI:"(R)-ethosuximide") association p(HGNC:DKK1)
pmid:26420483	a(CHEBI:"(R)-ethosuximide") association p(HGNC:AKT1)
pmid:26420483	a(CHEBI:"(R)-ethosuximide") association p(HGNC:GSK3B)
pmid:23164821	bp(GOBP:"non-canonical Wnt signaling pathway") isA bp(GOBP:"Wnt signaling pathway")
pmid:23164821	bp(PTS:"p53 signaling pathway") increases p(HGNC:DKK1)
pmid:23164821	bp(PTS:"p53 signaling pathway") increases p(HGNC:DKK1)
pmid:23164821	g(HGNC:DKK1) increases bp(GOBP:"Wnt signaling pathway, planar cell polarity pathway")
pmid:26420483	p(HGNC:AKT1) association a(CHEBI:"(R)-ethosuximide")
pmid:19519303	act(p(HGNC:AKT1)) increases p(HGNC:GSK3B, pmod(Ph, Ser, 9))
pmid:21598254	p(HGNC:AKT1) association bp(GOBP:"insulin receptor signaling pathway via phosphatidylinositol 3-kinase")
pmid:21598254	p(HGNC:AKT1) negativeCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:14636947	act(p(HGNC:AKT1), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:15283963	act(p(HGNC:AKT1), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:21598254	p(HGNC:AKT1) positiveCorrelation act(p(HGNC:OGT))
pmid:15283963	act(p(HGNC:AKT1), ma(kin)) association a(CHEBI:"insulin (human)")
pmid:23164821	p(HGNC:DKK4) increases p(HGNC:EGR1)
pmid:23164821	p(HGNC:DKK4) increases p(HGNC:FOS)
pmid:18494933	p(HGNC:GSK3B, pmod(Ph)) positiveCorrelation p(HGNC:DKK1)
pmid:19519303	p(HGNC:GSK3B, pmod(Ph)) decreases act(p(HGNC:GSK3B))
pmid:19519303	p(HGNC:GSK3B, pmod(Ph)) increases bp(GOBP:"apoptotic process")
pmid:18494933	p(HGNC:GSK3B, pmod(Ph)) increases p(HGNC:MAPT, pmod(Ph))
pmid:23164821	p(HGNC:KLF10) positiveCorrelation p(HGNC:APP, frag("672_713"))
pmid:23164821	p(HGNC:KLF10) increases p(HGNC:MAPT, pmod(Ph))
pmid:23164821	p(HGNC:KLF10) increases p(HGNC:MAPT, pmod(Ph))
pmid:23164821	p(HGNC:KLF10) increases bp(GOBP:"neuron death")
pmid:23164821	p(HGNC:NAB2) positiveCorrelation p(HGNC:APP, frag("672_713"))
pmid:23164821	p(HGNC:NAB2) increases p(HGNC:MAPT, pmod(Ph))
pmid:23164821	p(HGNC:NAB2) increases p(HGNC:MAPT, pmod(Ph))
pmid:23164821	p(HGNC:NAB2) increases bp(GOBP:"neuron death")
pmid:26809093	p(HGNC:WNT3A) decreases act(p(HGNC:NEFH), ma(GOBP:"protein polymerization"))
pmid:26809093	p(HGNC:WNT3A) decreases act(p(HGNC:MAP2), ma(GOBP:"protein polymerization"))
pmid:26809093	p(HGNC:WNT3A) decreases p(HGNC:MAPT, pmod(Ph))
pmid:24270208	p(RGD:Dkk1) negativeCorrelation bp(GOBP:"Wnt signaling pathway")
pmid:24270208	p(RGD:Dkk1) increases p(RGD:Mapt, pmod(Ph, Ser, 199))
pmid:24270208	p(RGD:Dkk1) increases p(RGD:Mapt, pmod(Ph, Ser, 202))
pmid:24270208	p(RGD:Dkk1) increases p(RGD:Mapt, pmod(Ph, Ser, 214))
pmid:24270208	p(RGD:Dkk1) increases p(RGD:Mapt, pmod(Ph, Ser, 396))
pmid:24270208	p(RGD:Dkk1) increases p(RGD:Mapt, pmod(Ph, Ser, 404))
pmid:23261660	path(MESHD:"Epilepsy, Temporal Lobe") association p(HGNC:DKK1)
pmid:26880631	path(MESHD:Osteoporosis) association p(HGNC:DKK1)
pmid:26880631	path(MESHD:Osteoporosis) association p(HGNC:DKK1)
pmid:23261660	path(MESHD:Stroke) association p(HGNC:DKK1)
pmid:24262633	path(MESHD:Stroke) association p(HGNC:NFE2L2)
pmid:24262633	path(MESHD:Stroke) negativeCorrelation p(HGNC:NFE2L2)
pmid:24863743	path(MESHD:Stroke) positiveCorrelation bp(HBP:neuroinflammation)
pmid:12218642	path(MESHD:Stroke) association p(HGNC:NOS3)
pmid:21297267	a(CHEBI:berberine) increases act(p(HGNC:SOD1))
pmid:21297267	a(CHEBI:berberine) decreases act(p(HGNC:GSK3B))
pmid:21297267	a(CHEBI:berberine) decreases a(CHEBI:malonaldehyde)
pmid:21297267	a(CHEBI:berberine) decreases a(MESHC:"calyculin A")
pmid:21297267	a(CHEBI:berberine) association bp(GOBP:"positive regulation of protein phosphatase type 2A activity")
pmid:16179266	a(CHEBI:melatonin) increases a(CHEBI:glutathione)
pmid:16179266	a(CHEBI:melatonin) decreases act(a(CHEBI:radical))
pmid:16364209	a(CHEBI:melatonin) decreases bp(GOBP:"inflammatory response")
pmid:16364209	a(CHEBI:melatonin) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:16364209	a(CHEBI:melatonin) decreases p(HGNC:APP, frag("672_713"))
pmid:16364209	a(CHEBI:melatonin) decreases p(HGNC:MAPT, pmod(Ph))
pmid:24512768	a(CHEBI:rutin) increases act(p(MGI:Sod1))
pmid:24512768	a(CHEBI:rutin) decreases path(MESHD:Inflammation)
pmid:24512768	a(CHEBI:rutin) decreases a(CHEBI:"nitric oxide")
pmid:24512768	a(CHEBI:rutin) decreases path(MESHD:"Alzheimer Disease")
pmid:24512768	a(CHEBI:rutin) decreases p(HGNC:APP, frag("672_713"))
pmid:24512768	a(CHEBI:rutin) decreases p(HGNC:APP, frag("672_713"))
pmid:24262633	bp(GOBP:"regulation of histone deacetylase activity") association act(p(HGNC:NFE2L2))
pmid:24586690	bp(GOBP:"regulation of histone deacetylase activity") association p(MGI:Runx1)
pmid:15295589	complex(a(CHEBI:"copper(1+)"), a(CHEBI:"hydrogen peroxide")) directlyIncreases a(CHEBI:"hydroxy group")
pmid:15295589	complex(a(CHEBI:"hydrogen peroxide"), a(CHEBI:"iron(2+)")) directlyIncreases a(CHEBI:"hydroxy group")
pmid:16179266	p(ECCODE:"1.15.1.1") equivalentTo p(FPLX:SOD)
pmid:16179266	p(FPLX:SOD) equivalentTo p(ECCODE:"1.15.1.1")
pmid:12094909	p(HGNC:CAT) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19519303	p(HGNC:CAT) positiveCorrelation bp(MESHPP:Longevity)
pmid:20064547	p(HGNC:KEAP1) association bp(MESHPP:"Oxidative Stress")
pmid:24262633	act(p(HGNC:NFE2L2)) association path(MESHD:"Amyotrophic Lateral Sclerosis")
pmid:24262633	act(p(HGNC:NFE2L2)) negativeCorrelation path(MESHD:"Amyotrophic Lateral Sclerosis")
pmid:24262633	act(p(HGNC:NFE2L2)) association path(MESHD:"Alzheimer Disease")
pmid:24262633	act(p(HGNC:NFE2L2)) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:20064547	p(HGNC:NFE2L2) association path(MESHD:"Alzheimer Disease")
pmid:24262633	act(p(HGNC:NFE2L2)) association path(MESHD:"Parkinson Disease")
pmid:24262633	act(p(HGNC:NFE2L2)) negativeCorrelation path(MESHD:"Parkinson Disease")
pmid:24262633	act(p(HGNC:NFE2L2)) association path(MESHD:Inflammation)
pmid:24262633	act(p(HGNC:NFE2L2)) association act(p(HGNC:MAPK14))
pmid:24262633	act(p(HGNC:NFE2L2)) association bp(GOBP:"regulation of histone deacetylase activity")
pmid:24262633	act(p(HGNC:NFE2L2)) association bp(MESHPP:"Oxidative Stress")
pmid:20064547	p(HGNC:NFE2L2) association bp(MESHPP:"Oxidative Stress")
pmid:24262633	act(p(HGNC:NFE2L2)) association path(MESHD:"Wounds and Injuries")
pmid:24262633	p(HGNC:NFE2L2) increases bp(GOBP:"response to oxidative stress")
pmid:24262633	p(HGNC:NFE2L2) increases bp(GOBP:"response to oxidative stress")
pmid:24262633	act(p(HGNC:NFE2L2)) association act(p(HGNC:GSK3B))
pmid:24262633	p(HGNC:NFE2L2) association p(HGNC:GSK3B)
pmid:24262633	p(HGNC:NFE2L2) association path(MESHD:"Brain Injuries, Traumatic")
pmid:24262633	p(HGNC:NFE2L2) negativeCorrelation path(MESHD:"Brain Injuries, Traumatic")
pmid:24262633	p(HGNC:NFE2L2) association path(MESHD:Stroke)
pmid:24262633	p(HGNC:NFE2L2) negativeCorrelation path(MESHD:Stroke)
pmid:24262633	act(p(HGNC:NFE2L2)) association p(HGNC:NFKB1)
pmid:24262633	act(p(HGNC:NFE2L2)) association p(HGNC:NFKB2)
pmid:24262633	act(p(HGNC:NFE2L2)) association bp(GOBP:"inflammatory response")
pmid:19805328	p(MGI:Nfe2l2) increases bp(GOBP:learning)
pmid:24262633	path(MESHD:"Amyotrophic Lateral Sclerosis") association act(p(HGNC:NFE2L2))
pmid:24262633	path(MESHD:"Amyotrophic Lateral Sclerosis") negativeCorrelation act(p(HGNC:NFE2L2))
pmid:22512552	path(MESHD:"Amyotrophic Lateral Sclerosis") positiveCorrelation a(CHEBI:"nitric oxide")
pmid:19076431	path(MESHD:"Amyotrophic Lateral Sclerosis") association bp(GOBP:"cell death")
pmid:14673212	path(MESHD:"Amyotrophic Lateral Sclerosis") association act(p(HGNC:CDK5), ma(kin))
pmid:14673212	path(MESHD:"Amyotrophic Lateral Sclerosis") association p(HGNC:MAPT, pmod(Ph))
pmid:21729720	a(CHEBI:"1-(3-chlorophenyl)piperazine") regulates p(HGNC:GABRA1)
pmid:12031754	a(CHEBI:Midazolam) decreases p(HGNC:GABRA6)
pmid:9523823	a(CHEBI:Midazolam) increases p(MGI:Gabrb3)
pmid:21222604	a(CHEBI:etazolate) isA a(CHEBI:"GABA modulator")
pmid:18397369	act(a(CHEBI:etazolate)) increases a(HBP:"sAPP-alpha")
pmid:20223232	a(CHEBI:etazolate) increases a(HBP:"sAPP-alpha")
pmid:21222604	a(CHEBI:etazolate) increases tloc(a(HBP:"sAPP-alpha"), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:18397369	act(a(CHEBI:etazolate)) increases bp(MESHPP:Neuroprotection)
pmid:20223232	a(CHEBI:etazolate) isA a(CHEBI:"EC 3.1.4.* (phosphoric diester hydrolase) inhibitor")
pmid:21222604	a(CHEBI:etazolate) isA a(CHEBI:"EC 3.1.4.* (phosphoric diester hydrolase) inhibitor")
pmid:20223232	a(CHEBI:etazolate) increases act(p(HGNC:ADAM10), ma(pep))
pmid:21222604	a(CHEBI:etazolate) increases act(p(HGNC:ADAM10), ma(pep))
pmid:20223232	act(a(CHEBI:etazolate)) increases bp(GOBP:"learning or memory")
pmid:21969301	a(MESHC:"Glatiramer Acetate") increases p(MGI:Egr1)
pmid:21969301	a(MESHC:"Glatiramer Acetate") increases p(HGNC:EGR1)
pmid:21969301	a(MESHC:"Glatiramer Acetate") increases bp(MESH:D000066829)
pmid:18397369	act(a(MESHC:Etazolate)) isA a(CHEBI:"GABA modulator")
pmid:18397369	act(a(MESHC:Etazolate)) increases a(HBP:"sAPP-alpha")
pmid:20223232	act(a(MESHC:Etazolate)) increases a(HBP:"sAPP-alpha")
pmid:18397369	act(a(MESHC:Etazolate)) increases bp(MESHPP:Neuroprotection)
pmid:24966471	a(MESHC:Glutamates) increases bp(GOBP:"cell death")
pmid:20888417	p(HGNC:GABBR2) increases bp(GOBP:"cAMP catabolic process")
pmid:20888417	p(HGNC:GABBR2) increases complex(GOCC:"potassium channel complex")
pmid:19909279	p(HGNC:GABRA1) association bp(GOBP:"regulation of synaptic plasticity")
pmid:19909279	p(HGNC:GABRA2) association bp(GOBP:"regulation of synaptic plasticity")
pmid:19909279	p(HGNC:GABRA3) association bp(GOBP:"regulation of synaptic plasticity")
pmid:19909279	p(HGNC:GABRA4) association bp(GOBP:"regulation of synaptic plasticity")
pmid:19909279	p(HGNC:GABRA5) association bp(GOBP:"regulation of synaptic plasticity")
pmid:19909279	p(HGNC:GABRA6) association bp(GOBP:"regulation of synaptic plasticity")
pmid:19909279	p(HGNC:GABRB1) association bp(GOBP:"regulation of synaptic plasticity")
pmid:19909279	p(HGNC:GABRB3) association bp(GOBP:"regulation of synaptic plasticity")
pmid:19909279	p(HGNC:GABRD) association bp(GOBP:"regulation of synaptic plasticity")
pmid:19909279	p(HGNC:GABRE) association bp(GOBP:"regulation of synaptic plasticity")
pmid:19909279	p(HGNC:GABRG1) association bp(GOBP:"regulation of synaptic plasticity")
pmid:19909279	p(HGNC:GABRG2) association bp(GOBP:"regulation of synaptic plasticity")
pmid:19909279	p(HGNC:GABRG3) association bp(GOBP:"regulation of synaptic plasticity")
pmid:19909279	p(HGNC:GABRP) association bp(GOBP:"regulation of synaptic plasticity")
pmid:19909279	p(HGNC:GABRQ) association bp(GOBP:"regulation of synaptic plasticity")
pmid:20938992	r(MGI:Gabrb3) association a(CHEBI:choline)
pmid:19519303	a(CHEBI:"1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate") increases act(p(HGNC:RPS6KB1))
pmid:19519303	a(CHEBI:"1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate") increases act(p(HGNC:GSK3B))
pmid:18217188	a(CHEBI:"17beta-estradiol") decreases p(HGNC:MAPT, pmod(Ph, Thr, 231))
pmid:18217188	a(CHEBI:"17beta-estradiol") decreases p(HGNC:MAPT, pmod(Ph, Thr, 205))
pmid:18217188	a(CHEBI:"17beta-estradiol") decreases p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:18217188	a(CHEBI:"17beta-estradiol") decreases p(HGNC:MAPT, pmod(Ph, Ser, 404))
pmid:18217188	a(CHEBI:"17beta-estradiol") decreases p(HGNC:MAPT, pmod(Ph, Ser, 199))
pmid:18217188	a(CHEBI:"17beta-estradiol") decreases p(HGNC:MAPT, pmod(Ph, Ser, 202))
pmid:18217188	a(CHEBI:"17beta-estradiol") increases p(HGNC:GSK3B, pmod(Ph, Ser, 9))
pmid:10850726	a(CHEBI:"Z-DEVD-FMK") decreases act(p(HGNC:CASP3))
pmid:10850726	a(CHEBI:"Z-DEVD-FMK") decreases p(HGNC:PRKCD)
pmid:10850726	a(CHEBI:"Z-DEVD-FMK") increases act(p(SFAM:"GSK3 Family"))
pmid:22496686	a(CHEBI:"copper atom") decreases act(p(HGNC:GSK3B))
pmid:22496686	a(CHEBI:"copper atom") directlyDecreases p(HGNC:APP, frag("672_713"))
pmid:11527574	a(CHEBI:"lithium(1+)") decreases act(p(HGNC:GSK3B))
pmid:15314261	a(CHEBI:"okadaic acid") increases p(HGNC:GSK3B, pmod(Ph, Ser, 9))
pmid:21893081	a(CHEBI:"okadaic acid") increases a(CHEBI:"reactive oxygen species")
pmid:21893081	a(CHEBI:"okadaic acid") increases a(CHEBI:"reactive oxygen species")
pmid:15314261	a(CHEBI:"okadaic acid") decreases complex(SCOMP:"PP2A Complex")
pmid:15314261	a(CHEBI:"okadaic acid") increases p(HGNC:MAPT, pmod(Ph))
pmid:15314261	a(CHEBI:"okadaic acid") increases bp(GOBP:"cell death")
pmid:10998059	a(CHEBI:alsterpaullone) decreases p(HGNC:MAPT, pmod(Ph))
pmid:10998059	a(CHEBI:alsterpaullone) decreases p(HGNC:MAPT, pmod(Ph))
pmid:10998059	a(CHEBI:alsterpaullone) negativeCorrelation act(p(HGNC:GSK3B))
pmid:10998059	a(CHEBI:alsterpaullone) negativeCorrelation act(p(HGNC:CDK5))
pmid:10998059	a(CHEBI:paullone) decreases act(p(HGNC:GSK3B))
pmid:19885299	a(CHEBI:rosiglitazone) decreases p(HGNC:GSK3B)
pmid:26113788	a(CHEBI:rosiglitazone) increases p(HGNC:SOCS1)
pmid:26113788	a(CHEBI:rosiglitazone) increases p(HGNC:SOCS3)
pmid:16982809	a(CHEBI:rosiglitazone) increases r(HGNC:THBS3)
pmid:17475839	a(CHEBI:rosiglitazone) increases p(HGNC:CD86)
pmid:19556978	a(CHEBI:rosiglitazone) association p(HGNC:LAMB2)
pmid:20003221	a(CHEBI:rosiglitazone) increases r(HGNC:STAR)
pmid:10850726	a(CHEBI:wortmannin) increases act(p(HGNC:PRKCD))
pmid:17120162	a(CHEBI:wortmannin) increases act(p(HGNC:GSK3B))
pmid:16511867	a(MESHC:cerebrolysin) decreases p(MGI:Cdk5)
pmid:16511867	a(MESHC:cerebrolysin) decreases p(MGI:Gsk3b)
pmid:16511867	a(MESHC:cerebrolysin) decreases p(MGI:App, pmod(Ph))
pmid:16511867	a(MESHC:cerebrolysin) decreases tloc(p(MGI:App), fromLoc(MESHCS:"Cell Surface Extensions"), toLoc(MESHCS:Endosomes))
pmid:16511867	a(MESHC:cerebrolysin) decreases a(MESHC:"Amyloid beta-Peptides")
pmid:22013558	a(MESHC:cerebrolysin) association path(MESHD:Inflammation)
pmid:19531281	a(MESHC:cerebrolysin) decreases p(HGNC:TNF)
pmid:19531281	a(MESHC:cerebrolysin) increases p(HGNC:IGF1)
pmid:22013558	a(MESHC:cerebrolysin) association p(HGNC:APP, frag("672_713"))
pmid:14628195	a(MESHC:cerebrolysin) decreases p(HGNC:APP, frag("672_713"))
pmid:16511867	a(MESHC:cerebrolysin) decreases path(MESHD:"Alzheimer Disease")
pmid:16511867	a(MESHC:cerebrolysin) decreases p(MGI:App, frag("672_713"))
pmid:16511867	a(MESHC:cerebrolysin) decreases r(MGI:App)
pmid:14628195	a(MESHC:cerebrolysin) increases bp(GOBP:"positive regulation of synaptic plasticity")
pmid:16511867	a(MESHC:cerebrolysin) causesNoChange p(MGI:Notch1)
pmid:16511867	a(MESHC:cerebrolysin) causesNoChange p(MGI:Mme)
pmid:16511867	a(MESHC:cerebrolysin) causesNoChange p(MGI:Ide)
pmid:21598254	bp(GOBP:"insulin receptor signaling pathway via phosphatidylinositol 3-kinase") negativeCorrelation act(p(HGNC:GSK3B))
pmid:19885299	bp(GOBP:"insulin receptor signaling pathway via phosphatidylinositol 3-kinase") negativeCorrelation bp(MESHPP:"Insulin Resistance")
pmid:21598254	bp(GOBP:"insulin receptor signaling pathway via phosphatidylinositol 3-kinase") negativeCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:21598254	bp(GOBP:"insulin receptor signaling pathway via phosphatidylinositol 3-kinase") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:21598254	bp(GOBP:"insulin receptor signaling pathway via phosphatidylinositol 3-kinase") association p(HGNC:AKT1)
pmid:21598254	bp(GOBP:"insulin receptor signaling pathway via phosphatidylinositol 3-kinase") association complex(GOCC:"phosphatidylinositol 3-kinase complex")
pmid:21598254	bp(GOBP:"insulin receptor signaling pathway via phosphatidylinositol 3-kinase") negativeCorrelation act(p(HGNC:CAPN1))
pmid:19885299	bp(GOBP:"insulin receptor signaling pathway") positiveCorrelation act(p(HGNC:INSR))
pmid:19519303	bp(GOBP:"insulin receptor signaling pathway") decreases act(p(HGNC:GSK3B))
pmid:24529528	bp(GOBP:"insulin receptor signaling pathway") negativeCorrelation path(MESHD:Inflammation)
pmid:19885299	bp(GOBP:"insulin receptor signaling pathway") positiveCorrelation bp(MESHPP:"Cell Survival")
pmid:19885299	bp(GOBP:"insulin receptor signaling pathway") association bp(MESHPP:"Energy Metabolism")
pmid:19885299	bp(GOBP:"insulin receptor signaling pathway") negativeCorrelation bp(MESHPP:"Oxidative Stress")
pmid:19885299	bp(GOBP:"insulin receptor signaling pathway") negativeCorrelation act(p(HGNC:TNF))
pmid:19885299	bp(GOBP:"insulin receptor signaling pathway") negativeCorrelation act(a(MESHC:Cytokines))
pmid:19885299	bp(GOBP:"insulin receptor signaling pathway") negativeCorrelation r(HGNC:APP)
pmid:19885299	bp(GOBP:"insulin receptor signaling pathway") decreases bp(HBP:"mitochondrial dysfunction")
pmid:19885299	bp(GOBP:"insulin receptor signaling pathway") association p(HGNC:SOS2)
pmid:19519303	bp(GOBP:"insulin receptor signaling pathway") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19519303	bp(GOBP:"insulin receptor signaling pathway") positiveCorrelation act(p(HGNC:IRS1))
pmid:19519303	bp(GOBP:"insulin receptor signaling pathway") negativeCorrelation p(HGNC:IRS1, pmod(Ph, Ser, 312))
pmid:19519303	bp(GOBP:"insulin receptor signaling pathway") increases act(p(HGNC:AKT1))
pmid:19519303	bp(GOBP:"insulin receptor signaling pathway") increases p(HGNC:MAPT, pmod(Ph))
pmid:15094078	bp(GOBP:"insulin receptor signaling pathway") increases p(HGNC:MAPT, pmod(Ph))
pmid:19519303	bp(GOBP:"insulin receptor signaling pathway") increases complex(GOCC:"neurofibrillary tangle")
pmid:19519303	bp(GOBP:"insulin receptor signaling pathway") decreases act(p(HGNC:APP, frag("672_713")))
pmid:19519303	bp(GOBP:"insulin receptor signaling pathway") negativeCorrelation bp(MESHPP:Longevity)
pmid:19519303	bp(GOBP:"insulin receptor signaling pathway") association act(r(HGNC:IDE), ma(tscript))
pmid:19013138	bp(GOBP:"insulin receptor signaling pathway") association p(MGI:Chat)
pmid:17440948	bp(GOBP:"insulin receptor signaling pathway") association g(HGNC:PPARG)
pmid:17440948	bp(GOBP:"insulin receptor signaling pathway") association g(HGNC:SOS2)
pmid:17440948	bp(GOBP:"insulin receptor signaling pathway") association g(HGNC:PCK1)
pmid:15094078	bp(GOBP:"insulin receptor signaling pathway") positiveCorrelation bp(GOBP:"energy homeostasis")
pmid:19885299	bp(GOBP:"insulin-like growth factor receptor signaling pathway") positiveCorrelation act(p(HGNC:IGF1R))
pmid:19519303	bp(GOBP:"insulin-like growth factor receptor signaling pathway") decreases act(p(HGNC:GSK3B))
pmid:19885299	bp(GOBP:"insulin-like growth factor receptor signaling pathway") regulates r(HGNC:MAPT)
pmid:19885299	bp(GOBP:"insulin-like growth factor receptor signaling pathway") regulates p(HGNC:MAPT, pmod(Ph))
pmid:19519303	bp(GOBP:"insulin-like growth factor receptor signaling pathway") increases p(HGNC:MAPT, pmod(Ph))
pmid:19885299	bp(GOBP:"insulin-like growth factor receptor signaling pathway") positiveCorrelation bp(MESHPP:"Cell Survival")
pmid:19885299	bp(GOBP:"insulin-like growth factor receptor signaling pathway") association bp(MESHPP:"Energy Metabolism")
pmid:19885299	bp(GOBP:"insulin-like growth factor receptor signaling pathway") negativeCorrelation bp(MESHPP:"Oxidative Stress")
pmid:19885299	bp(GOBP:"insulin-like growth factor receptor signaling pathway") negativeCorrelation act(p(HGNC:TNF))
pmid:19885299	bp(GOBP:"insulin-like growth factor receptor signaling pathway") negativeCorrelation act(a(MESHC:Cytokines))
pmid:19885299	bp(GOBP:"insulin-like growth factor receptor signaling pathway") negativeCorrelation r(HGNC:APP)
pmid:19885299	bp(GOBP:"insulin-like growth factor receptor signaling pathway") negativeCorrelation bp(HBP:"mitochondrial dysfunction")
pmid:19519303	bp(GOBP:"insulin-like growth factor receptor signaling pathway") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19519303	bp(GOBP:"insulin-like growth factor receptor signaling pathway") negativeCorrelation p(HGNC:IRS1, pmod(Ph, Ser, 312))
pmid:19519303	bp(GOBP:"insulin-like growth factor receptor signaling pathway") negativeCorrelation p(HGNC:IRS1, pmod(Ph, Ser, 616))
pmid:19519303	bp(GOBP:"insulin-like growth factor receptor signaling pathway") increases complex(GOCC:"neurofibrillary tangle")
pmid:19519303	bp(GOBP:"insulin-like growth factor receptor signaling pathway") increases p(HGNC:FOXO1, pmod(Ph))
pmid:19519303	bp(GOBP:"insulin-like growth factor receptor signaling pathway") association tloc(p(HGNC:FOXO1, pmod(Ph)), fromLoc(GOCC:intracellular), toLoc(GOCC:nucleus))
pmid:19429119	bp(GOBP:"regulation of cAMP-dependent protein kinase activity") association p(HGNC:LEP)
pmid:19429119	bp(GOBP:"regulation of cAMP-dependent protein kinase activity") decreases p(HGNC:MAPT, pmod(Ph))
pmid:19429119	bp(GOBP:"regulation of cAMP-dependent protein kinase activity") decreases p(HGNC:APP, frag("672_713"))
pmid:19429119	bp(GOBP:"regulation of cAMP-dependent protein kinase activity") decreases p(HGNC:APP, frag("672_711"))
pmid:21598254	bp(GOBP:"regulation of tau-protein kinase activity") association p(HGNC:MAPT, pmod(Ph))
pmid:19885299	bp(MESHPP:"Cell Survival") positiveCorrelation bp(GOBP:"insulin receptor signaling pathway")
pmid:19885299	bp(MESHPP:"Cell Survival") positiveCorrelation bp(GOBP:"insulin-like growth factor receptor signaling pathway")
pmid:19519303	bp(MESHPP:"Cell Survival") positiveCorrelation act(p(HGNC:INS))
pmid:19519303	bp(MESHPP:"Cell Survival") positiveCorrelation act(p(HGNC:IGF1))
pmid:22720189	bp(MESHPP:"Cell Survival") association m(HGNC:"MIR16-1")
pmid:22720189	bp(MESHPP:"Cell Survival") association m(HGNC:MIR132)
pmid:20157255	bp(MESHPP:"Cell Survival") association p(HGNC:LEP)
pmid:19885299	bp(MESHPP:"Energy Metabolism") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19885299	bp(MESHPP:"Energy Metabolism") association bp(GOBP:"insulin receptor signaling pathway")
pmid:19885299	bp(MESHPP:"Energy Metabolism") association bp(GOBP:"insulin-like growth factor receptor signaling pathway")
pmid:17049785	bp(PTS:"Insulin receptor signaling pathway") increases p(HGNC:GSK3B, pmod(Ph))
pmid:17049785	bp(PTS:"Insulin receptor signaling pathway") association p(HGNC:AKT1, pmod(Ph))
pmid:17049785	bp(PTS:"Insulin receptor signaling pathway") association p(SFAM:"PAK Family", pmod(Ph))
pmid:19885299	bp(PTS:"PI3K/AKT signaling") increases act(p(SFAM:"AKT Family"))
pmid:19885299	bp(PTS:"Ras/MEK/ERK pathway") increases bp(GOBP:"cell growth")
pmid:19885299	bp(PTS:"Ras/MEK/ERK pathway") increases bp(MESHPP:"Cell Survival")
pmid:23181169	act(complex(SCOMP:"Nfkb Complex")) increases p(HGNC:APP, frag("672_713"))
pmid:22122372	complex(p(HGNC:APBB1), p(HGNC:TFCP2), p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")) association act(g(HGNC:GSK3B))
pmid:22496686	complex(p(HGNC:APC), p(HGNC:CSNK1A1), p(HGNC:CTNNB1), p(HGNC:GSK3B), p(SFAM:"AXIN Family")) increases act(p(HGNC:GSK3B))
pmid:11212302	complex(p(HGNC:APC), p(HGNC:CSNK1A1), p(HGNC:CTNNB1), p(HGNC:GSK3B), p(SFAM:"AXIN Family")) increases act(p(HGNC:GSK3B))
pmid:22613765	complex(p(HGNC:APC), p(HGNC:CSNK1A1), p(HGNC:CTNNB1), p(HGNC:GSK3B), p(SFAM:"AXIN Family")) increases p(HGNC:CTNNB1, pmod(Ub))
pmid:21352912	p(HGNC:APC) association act(p(HGNC:GSK3B))
pmid:11212302	p(HGNC:CSNK1A1) increases p(HGNC:CTNNB1, pmod(Ph))
pmid:11212302	p(SFAM:"AXIN Family") increases complex(p(HGNC:APC), p(HGNC:CSNK1A1), p(HGNC:CTNNB1), p(HGNC:GSK3B), p(SFAM:"AXIN Family"))
pmid:10341227	p(SFAM:"AXIN Family") decreases p(HGNC:CTNNB1)
pmid:10341227	p(SFAM:"AXIN Family") increases complex(p(HGNC:CTNNB1), p(HGNC:GSK3B))
pmid:10341227	p(SFAM:"AXIN Family") increases act(p(HGNC:GSK3B))
pmid:21352912	p(SFAM:"AXIN Family") association act(p(HGNC:GSK3B))
pmid:17389597	complex(p(HGNC:CDH2), p(HGNC:PSEN1)) positiveCorrelation tloc(p(HGNC:PSEN1), fromLoc(GOCC:intracellular), toLoc(GOCC:"cell surface"))
pmid:17389597	complex(p(HGNC:CDH2), p(HGNC:PSEN1)) negativeCorrelation p(HGNC:PSEN1, pmod(Ph))
pmid:17360711	complex(p(HGNC:CTNNB1), p(HGNC:PSEN1)) positiveCorrelation p(HGNC:CTNNB1, pmod(Ph))
pmid:17360711	complex(p(HGNC:CTNNB1), p(HGNC:PSEN1)) positiveCorrelation p(HGNC:CTNNB1, pmod(Ub))
pmid:21985244	complex(p(HGNC:GSK3B), p(HGNC:MAPT), p(HGNC:SNCA)) increases act(p(HGNC:GSK3B))
pmid:21985244	complex(p(HGNC:GSK3B), p(HGNC:MAPT), p(HGNC:SNCA)) directlyIncreases p(HGNC:MAPT, pmod(Ph))
pmid:19519303	complex(p(HGNC:GSK3B), p(HGNC:PPP2CA)) association p(HGNC:MAPT, pmod(Ph))
pmid:19519303	p(HGNC:PPP2CA) increases complex(p(HGNC:IGF1), p(HGNC:INSR))
pmid:19519303	act(p(HGNC:PPP2CA)) negativeCorrelation p(HGNC:PIK3CA)
pmid:19519303	act(p(HGNC:PPP2CA)) isA complex(p(HGNC:GSK3B), p(HGNC:PPP2CA))
pmid:19519303	act(p(HGNC:PPP2CA)) association bp(GOBP:"TOR signaling")
pmid:19519303	act(p(HGNC:PPP2CA)) association p(HGNC:MAPT, pmod(Ph))
pmid:19519303	p(HGNC:PPP2CA) decreases p(HGNC:MAPT, pmod(Ph))
pmid:8529836	act(p(HGNC:PPP2CA), ma(phos)) decreases p(HGNC:MAPT, pmod(Ph))
pmid:19519303	act(p(HGNC:PPP2CA)) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:23362255	act(p(HGNC:PPP2CA), ma(phos)) decreases p(HGNC:MAPT, pmod(Ph, Thr, 205))
pmid:23362255	act(p(HGNC:PPP2CA), ma(phos)) decreases p(HGNC:MAPT, pmod(Ph, Ser, 202))
pmid:23362255	act(p(HGNC:PPP2CA), ma(phos)) decreases p(HGNC:MAPT, pmod(Ph, Ser, 235))
pmid:23362255	act(p(HGNC:PPP2CA), ma(phos)) decreases p(HGNC:MAPT, pmod(Ph, Ser, 404))
pmid:19519303	act(complex(p(HGNC:IGF1), p(HGNC:INSR))) association p(HGNC:MAPT, pmod(Ph))
pmid:20847424	complex(p(HGNC:IGF1), p(HGNC:INSR)) increases p(HGNC:IRS1, pmod(Ph, Thr))
pmid:20847424	complex(p(HGNC:IGF1), p(HGNC:INSR)) increases p(HGNC:IRS2, pmod(Ph, Thr))
pmid:20847424	complex(p(HGNC:IGF1), p(HGNC:INSR)) increases p(HGNC:SHC1, pmod(Ph, Thr))
pmid:20847424	complex(p(HGNC:IGF1), p(HGNC:INSR)) increases p(HGNC:SHC2, pmod(Ph, Thr))
pmid:20847424	complex(p(HGNC:IGF1), p(HGNC:INSR)) increases p(HGNC:SHC3, pmod(Ph, Thr))
pmid:20847424	complex(p(HGNC:IGF1), p(HGNC:INSR)) increases p(HGNC:SHC4, pmod(Ph, Thr))
pmid:22122372	act(g(HGNC:GSK3B)) association complex(p(HGNC:APBB1), p(HGNC:TFCP2), p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site"))
pmid:21985244	p(FPLX:HSPA) decreases p(HGNC:MAPT, pmod(Ph))
pmid:21985244	p(FPLX:HSPA) directlyDecreases p(HGNC:SNCA)
pmid:17954934	p(FPLX:HSPA) increases deg(p(HGNC:MAPT))
pmid:17954934	p(FPLX:HSPA) increases deg(p(HGNC:MAPT))
pmid:16316932	p(HGNC:BAX, pmod(Ph)) increases act(p(HGNC:BAX))
pmid:22496686	act(p(HGNC:BTRC)) decreases p(HGNC:CTNNB1)
pmid:11212302	act(p(HGNC:BTRC)) decreases p(HGNC:CTNNB1)
pmid:22496686	p(HGNC:CTNNB1, pmod(Ph)) increases act(p(HGNC:BTRC))
pmid:11212302	p(HGNC:CTNNB1, pmod(Ph)) increases act(p(HGNC:BTRC))
pmid:10341227	p(HGNC:CTNNB1, pmod(Ph)) decreases p(HGNC:CTNNB1)
pmid:11504726	p(HGNC:CTNNB1, pmod(Ph)) decreases p(HGNC:CTNNB1)
pmid:22496686	p(HGNC:CTNNB1, pmod(Ph)) increases deg(p(HGNC:CTNNB1))
pmid:15314261	p(HGNC:CTNNB1, pmod(Ph)) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:17360687	p(HGNC:CTNNB1, pmod(Ph)) association bp(GOBP:"apoptotic process")
pmid:17360711	p(HGNC:CTNNB1, pmod(Ph)) positiveCorrelation complex(p(HGNC:CTNNB1), p(HGNC:PSEN1))
pmid:17360711	p(HGNC:CTNNB1, pmod(Ub)) positiveCorrelation complex(p(HGNC:CTNNB1), p(HGNC:PSEN1))
pmid:17902168	p(HGNC:DPYSL2, pmod(Ph, Ser, 522)) positiveCorrelation act(p(HGNC:GSK3A))
pmid:15522877	p(HGNC:FRAT2) increases act(p(HGNC:GSK3B))
pmid:20847424	p(HGNC:GSK3A, pmod(Ph, Ser, 21)) decreases act(p(HGNC:GSK3A))
pmid:19519303	p(HGNC:HSF1) increases bp(GOBP:"insulin receptor signaling pathway")
pmid:19885299	act(p(HGNC:IGF1R)) increases p(HGNC:IRS4, pmod(Ph))
pmid:19885299	act(p(HGNC:IGF1R)) positiveCorrelation bp(GOBP:"insulin-like growth factor receptor signaling pathway")
pmid:19885299	p(HGNC:IGF1R) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:21916834	p(HGNC:IGF1R) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19885299	act(p(HGNC:IRS1)) increases bp(PTS:"PI3K/AKT signaling")
pmid:19885299	act(p(HGNC:IRS1)) decreases bp(MESHPP:"Oxidative Stress")
pmid:19885299	act(p(HGNC:IRS1)) increases bp(PTS:"Ras/MEK/ERK pathway")
pmid:19605645	deg(p(HGNC:IRS1)) positiveCorrelation p(HGNC:IRS1, pmod(Ph, Ser, 312))
pmid:19885299	p(HGNC:IRS1) negativeCorrelation bp(MESHPP:"Insulin Resistance")
pmid:19519303	p(HGNC:IRS1) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19519303	act(p(HGNC:IRS1)) positiveCorrelation bp(GOBP:"insulin receptor signaling pathway")
pmid:19519303	p(HGNC:IRS1) association bp(MESHPP:Longevity)
pmid:21289241	act(p(HGNC:IRS1)) association p(HGNC:RPS6KB1)
pmid:19885299	p(HGNC:IRS1, pmod(Ph)) increases act(p(HGNC:IRS1))
pmid:19885299	act(p(HGNC:IRS2)) increases bp(PTS:"PI3K/AKT signaling")
pmid:19885299	act(p(HGNC:IRS2)) decreases bp(MESHPP:"Oxidative Stress")
pmid:19885299	act(p(HGNC:IRS2)) increases bp(PTS:"Ras/MEK/ERK pathway")
pmid:19519303	p(HGNC:IRS2) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19885299	p(HGNC:IRS2, pmod(Ph)) increases act(p(HGNC:IRS2))
pmid:19885299	act(p(HGNC:IRS4)) decreases bp(MESHPP:"Oxidative Stress")
pmid:19885299	act(p(HGNC:IRS4)) increases p(HGNC:GRB2)
pmid:19885299	act(p(HGNC:IRS4)) increases bp(PTS:"Ras/MEK/ERK pathway")
pmid:19885299	p(HGNC:IRS4, pmod(Ph)) increases act(p(HGNC:IRS4))
pmid:17160145	p(HGNC:JUN) association complex(p(HGNC:CDK5), p(HGNC:CDK5R1))
pmid:20351102	p(HGNC:LRP2) association p(HGNC:IGF1)
pmid:20637285	p(HGNC:LRP2) increases deg(a(CHEBI:"amyloid-beta"))
pmid:17077814	p(HGNC:LRP2) increases p(HGNC:CLU)
pmid:12191990	act(p(HGNC:MAPK10)) increases p(HGNC:MAPT, pmod(Ph))
pmid:18650430	p(HGNC:MAPK10) association a(HBP:"YENPTY endocytosis motif (APP)")
pmid:9202310	act(p(HGNC:MAPK10), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 422))
pmid:9202310	act(p(HGNC:MAPK10), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 181))
pmid:9202310	act(p(HGNC:MAPK10), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Thr, 205))
pmid:9202310	act(p(HGNC:MAPK10), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 202))
pmid:9202310	act(p(HGNC:MAPK10), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:12387894	p(HGNC:MAPT, pmod(Glyco)) increases act(p(HGNC:GSK3B))
pmid:12387894	p(HGNC:MAPT, pmod(Glyco)) association path(HBP:Neurodegeneration)
pmid:12387894	p(HGNC:MAPT, pmod(Glyco)) increases p(HGNC:MAPT, pmod(Ph, Thr, 181))
pmid:12387894	p(HGNC:MAPT, pmod(Glyco)) increases p(HGNC:MAPT, pmod(Ph, Ser, 202))
pmid:12387894	p(HGNC:MAPT, pmod(Glyco)) increases p(HGNC:MAPT, pmod(Ph, Thr, 205))
pmid:12387894	p(HGNC:MAPT, pmod(Glyco)) increases p(HGNC:MAPT, pmod(Ph, Ser, 404))
pmid:12387894	p(HGNC:MAPT, pmod(Glyco)) increases p(HGNC:MAPT, pmod(Ph, Thr, 217))
pmid:12387894	p(HGNC:MAPT, pmod(Glyco)) increases act(p(HGNC:CDK5), ma(kin))
pmid:12435421	p(HGNC:MAPT, pmod(Glyco)) regulates p(HGNC:MAPT, pmod(Ph))
pmid:16257959	p(HGNC:MAPT, pmod(Ph, Ser, 262)) positiveCorrelation act(p(HGNC:MARK2))
pmid:24884485	p(HGNC:MAPT, pmod(Ph, Ser, 396)) negativeCorrelation bp(GOBP:cognition)
pmid:16257959	act(p(HGNC:MARK2)) positiveCorrelation p(HGNC:MAPT, pmod(Ph, Ser, 262))
pmid:16257959	p(HGNC:MARK2, pmod(Ph)) increases act(p(HGNC:MARK2))
pmid:15773910	p(HGNC:MTOR, pmod(Ph, Ser, 2448)) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:19519303	p(HGNC:PIK3CA) negativeCorrelation act(p(HGNC:GSK3B))
pmid:19519303	p(HGNC:PIK3CA) negativeCorrelation act(p(HGNC:PPP2CA))
pmid:17120162	act(p(HGNC:PRKACA), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:17078951	act(p(HGNC:PRKACA)) increases p(HGNC:MAPT, pmod(Ph))
pmid:12435421	act(p(HGNC:PRKACA), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:10850726	act(p(HGNC:PRKCD, frag("?"))) increases p(SFAM:"GSK3 Family", pmod(Ph))
pmid:10850726	act(p(HGNC:PRKCD, frag("?"))) decreases act(p(SFAM:"GSK3 Family"))
pmid:17389597	p(HGNC:PSEN1, pmod(Ph)) negativeCorrelation complex(p(HGNC:CDH2), p(HGNC:PSEN1))
pmid:17360711	p(HGNC:PSEN1, pmod(Ph, Ser, 353)) decreases complex(p(HGNC:CTNNB1), p(HGNC:PSEN1))
pmid:17360711	p(HGNC:PSEN1, pmod(Ph, Ser, 357)) decreases complex(p(HGNC:CTNNB1), p(HGNC:PSEN1))
pmid:16511867	p(MGI:Cdk5) increases p(MGI:App, pmod(Ph))
pmid:16511867	p(MGI:Gsk3b) increases p(MGI:App, pmod(Ph))
pmid:21945540	act(p(MGI:Gsk3b)) negativeCorrelation act(p(SFAM:"CREB Family"))
pmid:22122372	act(p(MGI:Gsk3b)) increases p(MGI:Mapt, pmod(Ph))
pmid:24808823	p(MGI:Mapt) association p(MGI:Ttbk1)
pmid:12387894	path(HBP:Neurodegeneration) association p(HGNC:MAPT, pmod(Glyco))
pmid:21945540	r(HGNC:BDNF) positiveCorrelation act(p(SFAM:"CREB Family"))
pmid:18675468	bp(GOBP:"membrane lipid catabolic process") negativeCorrelation bp(GOBP:"sodium ion homeostasis")
pmid:18675468	bp(GOBP:"membrane lipid catabolic process") negativeCorrelation bp(GOBP:"calcium ion homeostasis")
pmid:26113788	a(CHEBI:"15-deoxy-Delta(12,14)-prostaglandin J2") increases p(HGNC:SOCS3)
pmid:20715097	a(CHEBI:"2,3,7,8-tetrachlorodibenzodioxine") increases p(MGI:Il2ra)
pmid:17475839	a(CHEBI:"GW 9662") decreases p(HGNC:CD86)
pmid:19885299	a(CHEBI:"PPARgamma agonist") decreases path(MESHD:Inflammation)
pmid:19885299	a(CHEBI:"PPARgamma agonist") decreases act(a(MESH:D017628))
pmid:11755002	a(CHEBI:"PPARgamma agonist") decreases bp(GOBP:"chronic inflammatory response")
pmid:23254638	a(CHEBI:"S-nitrosoglutathione") association path(MESHD:Inflammation)
pmid:23254638	a(CHEBI:"S-nitrosoglutathione") regulates path(MESHD:Inflammation)
pmid:23254638	a(CHEBI:"S-nitrosoglutathione") decreases p(RGD:Icam1)
pmid:23254638	a(CHEBI:"S-nitrosoglutathione") increases bp(GOBP:memory)
pmid:23254638	a(CHEBI:"S-nitrosoglutathione") increases bp(GOBP:learning)
pmid:23254638	a(CHEBI:"S-nitrosoglutathione") decreases p(RGD:Vcam1)
pmid:23254638	a(CHEBI:"S-nitrosoglutathione") decreases p(HGNC:APP, frag("672_713"))
pmid:23254638	a(CHEBI:"S-nitrosoglutathione") decreases act(complex(SCOMP:"Nfkb Complex"))
pmid:23254638	a(CHEBI:"S-nitrosoglutathione") decreases act(p(HGNC:STAT3))
pmid:23254638	a(CHEBI:"S-nitrosoglutathione") decreases p(HGNC:VCAM1)
pmid:23254638	a(CHEBI:"S-nitrosoglutathione") decreases p(HGNC:ICAM1)
pmid:22710916	a(CHEBI:"gamma-secretase modulator") decreases act(complex(SCOMP:"gamma Secretase Complex"), ma(cat))
Other:123	a(CHEBI:"gamma-secretase modulator") decreases act(complex(SCOMP:"gamma Secretase Complex"))
pmid:22087836	a(CHEBI:"gamma-secretase modulator") decreases act(complex(SCOMP:"gamma Secretase Complex"), ma(pep))
pmid:22710916	a(CHEBI:"gamma-secretase modulator") decreases p(HGNC:APP, frag("672_713"))
pmid:22710916	a(CHEBI:"gamma-secretase modulator") increases a(MESHC:"amyloid beta-protein (1-38)")
pmid:22087836	a(CHEBI:"gamma-secretase modulator") decreases rxn(reactants(p(HGNC:NOTCH1)), products(p(HGNC:NOTCH1, frag("?"))))
pmid:20539903	a(CHEBI:"nicotinic acid") increases p(HGNC:VTN)
pmid:19383491	a(CHEBI:"non-steroidal anti-inflammatory drug") decreases path(MESHD:"Alzheimer Disease")
pmid:20003262	a(CHEBI:"quinolinic acid") increases bp(HBP:neuroinflammation)
pmid:20003262	a(CHEBI:"quinolinic acid") increases p(HGNC:IL1B)
pmid:24621589	a(CHEBI:Nicardipine) decreases bp(GOBP:"inflammatory response")
pmid:24621589	a(CHEBI:Nicardipine) decreases p(MGI:Nos2)
pmid:24621589	a(CHEBI:Nicardipine) decreases p(MGI:Ptgs2)
pmid:26113788	a(CHEBI:Thrombin) increases bp(HBP:neuroinflammation)
pmid:20937084	a(CHEBI:bradykinin) association path(MESHD:Inflammation)
pmid:24262203	a(CHEBI:corticosteroid) decreases p(HGNC:APP, frag("672_713"))
pmid:24262203	a(CHEBI:corticosteroid) decreases act(p(HGNC:S100A9))
pmid:24262203	a(CHEBI:corticosteroid) decreases bp(HBP:neuroinflammation)
pmid:10222124	a(CHEBI:dipyridamole) decreases path(MESHD:Inflammation)
pmid:10222124	a(CHEBI:dipyridamole) increases a(CHEBI:"3',5'-cyclic GMP")
pmid:21399480	a(CHEBI:fluoxetine) increases p(HGNC:GRN)
pmid:21399480	a(CHEBI:fluoxetine) increases p(HGNC:SORCS1)
pmid:26113788	a(CHEBI:ganglioside) increases bp(HBP:neuroinflammation)
pmid:24290604	a(CHEBI:genistein) association p(HGNC:TLR4)
pmid:24290604	a(CHEBI:genistein) decreases p(HGNC:APP, frag("25_35"))
pmid:24290604	a(CHEBI:genistein) increases path(MESHD:Inflammation)
pmid:18759972	a(CHEBI:lipopolysaccharide) increases bp(GOBP:"inflammatory response")
pmid:26113788	a(CHEBI:lipopolysaccharide) increases bp(HBP:neuroinflammation)
pmid:25681350	a(CHEBI:lipopolysaccharide) increases p(HGNC:TLR4)
pmid:24587007	a(CHEBI:lipopolysaccharide) increases a(CHEBI:"nitric oxide")
pmid:24587007	a(CHEBI:lipopolysaccharide) increases a(CHEBI:"reactive oxygen species")
pmid:20363256	a(CHEBI:mifepristone) decreases r(HGNC:NFKBIA)
pmid:17584828	a(CHEBI:mifepristone) increases r(HGNC:LAMC2)
pmid:17584828	a(CHEBI:mifepristone) decreases r(HGNC:STAR)
pmid:23312564	a(CHEBI:mifepristone) association p(HGNC:APP)
pmid:23312564	a(CHEBI:mifepristone) decreases p(HGNC:APP, frag("672_713"))
pmid:23312564	a(CHEBI:mifepristone) decreases path(MESHD:Tauopathies)
pmid:14699072	a(CHEBI:raloxifene) association r(HGNC:IL4R)
pmid:20937084	a(CHEBI:somatostatin) association path(MESHD:Inflammation)
pmid:18340409	a(CHEBI:tetrachloromethane) decreases p(RGD:Il2ra)
pmid:25024322	a(CTO:"Clinical_Dementia_Rating_Scale-sum_of_boxes") positiveCorrelation p(HGNC:CHI3L1)
pmid:25024322	a(CTO:"Mini_Mental_State_Examination") positiveCorrelation p(HGNC:CHI3L1)
pmid:20454929	a(MESH:D001792) increases p(HGNC:PLA2G7)
pmid:20454929	a(MESH:D001792) increases p(HGNC:"MT-CO2")
pmid:23407992	a(MESH:D006624) association p(HGNC:TREM2)
pmid:23407992	a(MESH:D019579) association p(HGNC:TREM2)
pmid:23407992	a(MESH:D066127) association p(HGNC:TREM2)
pmid:20454929	a(MESHC:Chemokines) increases bp(GOBP:"inflammatory response")
pmid:23231993	act(a(MESHC:Cytokines)) association p(HGNC:ANXA1)
pmid:19885299	act(a(MESHC:Cytokines)) negativeCorrelation bp(GOBP:"insulin receptor signaling pathway")
pmid:19885299	act(a(MESHC:Cytokines)) negativeCorrelation bp(GOBP:"insulin-like growth factor receptor signaling pathway")
pmid:20847424	act(a(MESHC:Cytokines)) association p(HGNC:IRS1, pmod(Ph, Thr))
pmid:20847424	act(a(MESHC:Cytokines)) association p(HGNC:IRS2, pmod(Ph, Thr))
pmid:20847424	act(a(MESHC:Cytokines)) association p(HGNC:SHC1, pmod(Ph, Thr))
pmid:20847424	act(a(MESHC:Cytokines)) association p(HGNC:SHC2, pmod(Ph, Thr))
pmid:20847424	act(a(MESHC:Cytokines)) association p(HGNC:SHC3, pmod(Ph, Thr))
pmid:20847424	act(a(MESHC:Cytokines)) association p(HGNC:SHC4, pmod(Ph, Thr))
pmid:1632469	act(a(MESHC:Cytokines)) association p(HGNC:LRP1)
pmid:20454929	a(MESHC:Interleukins) increases bp(GOBP:"inflammatory response")
pmid:25024322	a(NIFT:"Free and Cued Selective Reminding Test") positiveCorrelation p(HGNC:CHI3L1)
pmid:26996954	a(NIFT:"Grey matter volume") association p(HGNC:SORL1)
pmid:26996954	a(NIFT:"Grey matter volume") negativeCorrelation g(DBSNP:rs3824968)
pmid:26113788	bp(GOBP:"JAK-STAT cascade") increases bp(HBP:neuroinflammation)
pmid:26113788	bp(GOBP:"JAK-STAT cascade") increases a(CHEBI:lipopolysaccharide)
pmid:26113788	bp(GOBP:"JAK-STAT cascade") increases p(HGNC:IFNG)
pmid:26113788	bp(GOBP:"JAK-STAT cascade") increases a(CHEBI:ganglioside)
pmid:26113788	bp(GOBP:"JAK-STAT cascade") increases a(CHEBI:Thrombin)
pmid:20413894	bp(GOBP:"astrocyte activation") positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22024597	bp(GOBP:"chronic inflammatory response") increases bp(GOBP:"neuron apoptotic process")
pmid:22441986	bp(GOBP:"chronic inflammatory response") increases bp(GOBP:"production of molecular mediator involved in inflammatory response")
pmid:22441986	bp(GOBP:"chronic inflammatory response") increases p(HGNC:TNF)
pmid:11755002	bp(GOBP:"chronic inflammatory response") association p(HGNC:PPARG)
pmid:21143158	bp(GOBP:"cytokine production involved in inflammatory response") association path(MESHD:Gliosis)
pmid:21143158	bp(GOBP:"cytokine production involved in inflammatory response") positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22441986	bp(GOBP:"cytokine production involved in inflammatory response") association path(MESHD:"Alzheimer Disease")
pmid:22441986	bp(GOBP:"cytokine production involved in inflammatory response") association p(MGI:Tnf)
pmid:23407992	bp(GOBP:"cytokine production") association bp(GOBP:"inflammatory response")
pmid:23407992	bp(GOBP:"cytokine secretion") association bp(GOBP:"inflammatory response")
pmid:23231993	bp(GOBP:"cytoskeleton organization") association p(HGNC:ANXA1)
pmid:22496686	bp(GOBP:"immune response to tumor cell") association p(HGNC:CD44)
pmid:22441986	bp(GOBP:"immune response") increases bp(GOBP:"chronic inflammatory response")
pmid:15688347	bp(GOBP:"immune response") association complex(p(HGNC:CD40), p(HGNC:CD40LG))
pmid: 26517285	bp(GOBP:"immune response") association bp(GOBP:"microglial cell activation")
pmid:25681350	bp(GOBP:"macrophage activation") increases bp(GOBP:"inflammatory response")
pmid:25681350	bp(GOBP:"myeloid dendritic cell activation") increases bp(GOBP:"inflammatory response")
pmid:18997293	bp(GOBP:"nerve growth factor production") increases p(HGNC:NGF)
pmid:22277195	bp(GOBP:"production of molecular mediator involved in inflammatory response") increases bp(GOBP:"neuron apoptotic process")
pmid:22277195	bp(GOBP:"production of molecular mediator involved in inflammatory response") increases path(MESHD:"Neurogenic Inflammation")
pmid:20555131	bp(GOBP:"production of molecular mediator involved in inflammatory response") decreases bp(GOBP:cognition)
pmid:19149696	bp(GOBP:"regulation of dendritic cell antigen processing and presentation") association p(HGNC:CCR7)
pmid:20489155	bp(GOBP:"wound healing") association p(HGNC:GRN)
pmid:19499146	bp(GOBP:phagocytosis) association a(MESHCS:Lysosomes)
pmid:25681350	bp(GOBP:phagocytosis) decreases p(HGNC:APP, frag("672_713"))
pmid:21329555	complex(GOCC:"NF-kappaB complex") association path(MESHD:Inflammation)
pmid:21329555	complex(GOCC:"NF-kappaB complex") equivalentTo complex(p(HGNC:NFKB1), p(HGNC:NFKB1))
pmid:20127816	complex(GOCC:"inflammasome complex") increases act(p(HGNC:IL1B))
pmid:25681350	complex(GOCC:"inflammasome complex") increases act(p(HGNC:IL1B))
pmid:20127816	complex(GOCC:"inflammasome complex") increases act(p(HGNC:IL18))
pmid:20127816	complex(GOCC:"inflammasome complex") increases act(p(HGNC:CASP1))
pmid:20127816	complex(GOCC:"inflammasome complex") increases act(p(HGNC:IL33))
pmid:12675915	complex(a(CHEBI:noradrenaline), p(HGNC:ADRB1)) decreases path(MESHD:Inflammation)
pmid:12675915	complex(a(CHEBI:noradrenaline), p(HGNC:ADRB2)) decreases path(MESHD:Inflammation)
pmid:12675915	complex(a(CHEBI:noradrenaline), p(HGNC:ADRB3)) decreases path(MESHD:Inflammation)
pmid:22355794	complex(p(HGNC:APP), p(HGNC:LAMC1)) association bp(GOBP:"cell-matrix adhesion")
pmid:22355794	p(HGNC:LAMC1) increases bp(GOBP:"cell-matrix adhesion")
pmid:22198949	complex(p(HGNC:APP, frag("672_713")), p(MGI:Tlr2)) increases bp(GOBP:"inflammatory response")
pmid:22198949	complex(p(HGNC:APP, frag("672_713")), p(MGI:Tlr2)) increases bp(GOBP:"inflammatory response")
pmid:22198949	p(MGI:Tlr2) increases bp(GOBP:"inflammatory response")
pmid:22198949	p(MGI:Tlr2) increases complex(p(HGNC:APP, frag("672_713")), p(MGI:Tlr2))
pmid:18938162	complex(p(HGNC:CD200), p(HGNC:CD200R1)) decreases path(MESHD:Inflammation)
pmid:18938162	p(HGNC:CD200) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:18938162	p(HGNC:CD200) decreases bp(HBP:neuroinflammation)
pmid:18938162	p(HGNC:CD200R1) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:18938162	p(HGNC:CD200R1) decreases bp(HBP:neuroinflammation)
pmid:17572512	complex(p(HGNC:CD36), p(HGNC:CD47), p(HGNC:THBS1)) association bp(GOBP:"inflammatory response")
pmid:21209080	act(complex(p(HGNC:DIAPH1), p(HGNC:MOK), p(HGNC:S100B))) increases bp(GOBP:"telencephalon microglial cell migration")
pmid:19457124	complex(p(HGNC:HSPD1), p(HGNC:TREM2)) increases act(p(HGNC:TREM2))
pmid:16887805	p(HGNC:HSPD1) increases act(complex(GOCC:"respiratory chain complex IV"))
pmid:16887805	p(HGNC:HSPD1) increases bp(GOBP:"oxidative phosphorylation")
pmid:23533697	p(HGNC:TREM2) decreases bp(GOBP:"response to oxidative stress")
pmid:23533697	p(HGNC:TREM2) decreases bp(GOBP:"response to oxidative stress")
pmid:23533697	p(HGNC:TREM2) decreases path(MESHD:Inflammation)
pmid:23533697	p(HGNC:TREM2) association bp(GOBP:"inflammatory response")
pmid:23533697	p(HGNC:TREM2) decreases bp(GOBP:"inflammatory response")
pmid:23150934	p(HGNC:TREM2) decreases bp(GOBP:"inflammatory response")
pmid:25681350	p(HGNC:TREM2) decreases bp(GOBP:"inflammatory response")
pmid:23533697	p(HGNC:TREM2) increases bp(GOBP:phagocytosis)
pmid:23150934	p(HGNC:TREM2) increases bp(GOBP:phagocytosis)
pmid:25681350	p(HGNC:TREM2) increases bp(GOBP:phagocytosis)
pmid:23533697	p(HGNC:TREM2) decreases bp(GOBP:"cytokine production")
pmid:23150934	p(HGNC:TREM2) decreases bp(GOBP:"cytokine production")
pmid:23407992	p(HGNC:TREM2) decreases bp(GOBP:"cytokine production")
pmid:23533697	p(HGNC:TREM2) increases path(MESHD:"Alzheimer Disease")
pmid:24355566	p(HGNC:TREM2) association path(MESHD:"Alzheimer Disease")
pmid:25681350	p(HGNC:TREM2) increases act(p(HGNC:CCR7))
pmid:19149696	p(HGNC:TREM2) increases p(HGNC:CCR7)
pmid:25681350	p(HGNC:TREM2) association bp(GOBP:"microglial cell activation")
pmid:25681350	p(HGNC:TREM2) decreases p(HGNC:TNF)
pmid:25681350	p(HGNC:TREM2) decreases p(HGNC:IL6)
pmid:25681350	p(HGNC:TREM2) decreases p(HGNC:IFNG)
pmid:24355566	p(HGNC:TREM2) increases bp(GOBP:"regulation of inflammatory response")
pmid:24355566	p(HGNC:TREM2) increases bp(GOBP:"regulation of phagocytosis")
pmid:23407992	p(HGNC:TREM2) association a(MESH:D006624)
pmid:23407992	p(HGNC:TREM2) association a(MESH:D066127)
pmid:23407992	p(HGNC:TREM2) association a(MESH:D019579)
pmid:23407992	p(HGNC:TREM2) decreases bp(GOBP:"cytokine secretion")
pmid:19149696	p(HGNC:TREM2) increases bp(GOBP:"regulation of dendritic cell antigen processing and presentation")
pmid:21329555	complex(p(HGNC:NFKB1), p(HGNC:NFKB1)) equivalentTo complex(GOCC:"NF-kappaB complex")
pmid:25681350	complex(p(HGNC:NFKB1), p(HGNC:RELB)) increases p(HGNC:CHI3L1)
pmid:21143158	p(HGNC:TNFSF10) increases complex(p(HGNC:TNFRSF10B), p(HGNC:TNFSF10))
pmid:25681350	complex(p(HGNC:TREM2), p(HGNC:TYROBP)) increases bp(GOBP:"macrophage activation")
pmid:25681350	complex(p(HGNC:TREM2), p(HGNC:TYROBP)) increases bp(GOBP:"myeloid dendritic cell activation")
pmid:12080485	complex(p(HGNC:TREM2), p(HGNC:TYROBP)) increases bp(GOBP:"immune response")
pmid:22441986	complex(p(MGI:Tnf), p(MGI:Tnfrsf1a)) increases bp(GOBP:"positive regulation of apoptotic process")
pmid:22441986	complex(p(MGI:Tnf), p(MGI:Tnfrsf1a)) increases p(MGI:Lcn2)
pmid:22441986	complex(p(MGI:Tnf), p(MGI:Tnfrsf1a)) increases tloc(p(MGI:Lcn2), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:22441986	complex(p(MGI:Tnf), p(MGI:Tnfrsf1b)) increases bp(MESHPP:Neuroprotection)
pmid:17475839	composite(a(CHEBI:"9-cis-retinoic acid"), a(CHEBI:rosiglitazone)) decreases p(HGNC:CD80)
pmid:20363256	composite(a(CHEBI:dexamethasone), p(HGNC:CD28)) increases r(HGNC:NFKBIA)
pmid:22536436	a(CHEBI:dexamethasone) increases p(HGNC:MAPT, pmod(Ph))
pmid:22536436	a(CHEBI:dexamethasone) increases act(p(HGNC:CAPN1))
pmid:21718295	a(CHEBI:dexamethasone) decreases p(HGNC:APP, frag("672_713"))
pmid:22536436	a(CHEBI:dexamethasone) decreases p(SFAM:"AKT Family", pmod(Ph))
pmid:15289156	composite(a(CHEBI:estradiol), a(CHEBI:progesterone)) decreases r(HGNC:LAMC2)
pmid:17385278	composite(p(HGNC:IFNG), p(HGNC:IL1B), p(HGNC:TNF)) increases p(HGNC:NOS2)
pmid:13678430	composite(p(HGNC:IFNG), p(HGNC:IL5), p(HGNC:TNF)) increases a(CHEBI:"nitric oxide")
pmid:25681350	composite(p(HGNC:IL1B), p(HGNC:IL6)) increases p(HGNC:CHI3L1)
pmid:25681350	composite(p(HGNC:IL1B), p(HGNC:OSM)) increases p(HGNC:CHI3L1)
pmid:25681350	p(HGNC:OSM) increases p(HGNC:CHI3L1)
pmid:20847424	p(HGNC:PIK3R5) association act(p(HGNC:IRS1, pmod(Ph, Thr)))
pmid:20847424	p(HGNC:PIK3R5) association act(p(HGNC:IRS2, pmod(Ph, Thr)))
pmid:20847424	p(HGNC:PIK3R5) increases act(p(HGNC:GSK3A))
pmid:20847424	p(HGNC:PIK3R5) increases act(p(HGNC:GSK3B))
pmid:14766758	p(HGNC:RAC1) increases deg(p(HGNC:APP))
pmid: 21047645	g(DBSNP:rs5848) association r(HGNC:GRN)
pmid:19734902	g(DBSNP:rs639446) association g(HGNC:ANXA1)
pmid:19734902	g(HGNC:ANXA1) association g(DBSNP:rs639446)
pmid:19734902	g(HGNC:ANXA1) association path(MESHD:"Alzheimer Disease")
pmid:15817521	g(HGNC:PPARG) directlyDecreases bp(GOBP:"chronic inflammatory response")
pmid:15817521	g(HGNC:PPARG) decreases bp(GOBP:"inflammatory response")
pmid:17440948	g(HGNC:PPARG) association bp(GOBP:"insulin receptor signaling pathway")
pmid:19885299	g(HGNC:PPARG) decreases p(HGNC:APP, frag("672_713"))
pmid:19885299	g(HGNC:PPARG) increases deg(p(HGNC:APP, pmod(Ub)))
pmid:22279475	g(HGNC:TNF, var("c.308G>A")) association bp(GOBP:"inflammatory response")
pmid: 26517285	g(HGNC:TREM2) increases path(MESHD:"Alzheimer Disease")
pmid:20489155	m(HGNC:GRN) association p(HGNC:AGO2)
pmid:21640790	m(HGNC:MIR146A) decreases p(HGNC:CFH)
pmid:19801956	m(HGNC:MIR146A) decreases r(HGNC:CFH)
pmid:19801956	m(HGNC:MIR146A) association path(MESHD:"Alzheimer Disease")
pmid:19801956	m(HGNC:MIR146A) association bp(GOBP:"inflammatory response")
pmid:22209051	m(HGNC:MIR146A) positiveCorrelation bp(GOBP:"inflammatory response")
pmid:19801956	m(HGNC:MIR146A) increases r(HGNC:PAFAH2)
pmid:19801956	m(HGNC:MIR146A) increases r(HGNC:PTGS2)
pmid:19801956	m(HGNC:MIR146A) increases r(HGNC:IL1B)
pmid:20937840	m(HGNC:MIR146A) decreases r(HGNC:IRAK1)
pmid:22209051	m(HGNC:MIR146A) association r(HGNC:IRAK1)
pmid:20937840	m(HGNC:MIR146A) increases r(HGNC:IRAK2)
pmid:21640790	m(HGNC:MIR146A) decreases p(HGNC:IRAK1)
pmid:21640790	m(HGNC:MIR146A) decreases p(HGNC:TSPAN12)
pmid:22209051	m(HGNC:MIR146A) association r(HGNC:TRAF6)
pmid:24586483	m(HGNC:MIR146A) association bp(HBP:neuroinflammation)
pmid:21036908	m(HGNC:MIR155) association bp(GOBP:"inflammatory response")
pmid:25681350	m(HGNC:MIR34A) decreases p(HGNC:TREM2)
pmid:25681350	m(HGNC:MIR34A) increases p(HGNC:TREM2, var("p.Arg47His"))
pmid: 21047645	m(HGNC:MIR659) decreases r(HGNC:GRN)
pmid:20454929	p(HGNC:"MT-CO2") increases bp(GOBP:"inflammatory response")
pmid:24386594	p(HGNC:ADIPOQ) association path(MESHD:Inflammation)
pmid:24386594	p(HGNC:ADIPOQ) regulates act(p(SFAM:"INS Family"))
pmid:24386594	p(HGNC:ADIPOQ) regulates bp(GOBP:"fatty acid catabolic process")
pmid:24386594	p(HGNC:ADIPOQ) regulates bp(GOBP:"glucose homeostasis")
pmid:20489155	p(HGNC:AGO2) association m(HGNC:GRN)
pmid:23231993	p(HGNC:ANXA1) association act(a(MESHC:Cytokines))
pmid:23231993	p(HGNC:ANXA1) association bp(GOBP:"cytoskeleton organization")
pmid:19149696	p(HGNC:CCR7) association bp(GOBP:"regulation of dendritic cell antigen processing and presentation")
pmid:18615183	p(HGNC:CD14) association bp(GOBP:"inflammatory response")
pmid:22496686	p(HGNC:CD44) association bp(GOBP:"immune response to tumor cell")
pmid:22890100	p(HGNC:CHI3L1) positiveCorrelation path(MESHD:"Cognitive Dysfunction")
pmid:22890100	p(HGNC:CHI3L1) positiveCorrelation path(MESHD:"Cognitive Dysfunction")
pmid:22890100	p(HGNC:CHI3L1) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:21035623	p(HGNC:CHI3L1) prognosticBiomarkerFor path(MESHD:"Alzheimer Disease")
pmid:21035623	p(HGNC:CHI3L1) biomarkerFor path(MESHD:"Alzheimer Disease")
pmid:22890100	p(HGNC:CHI3L1) positiveCorrelation bp(HBP:neuroinflammation)
pmid:26836182	p(HGNC:CHI3L1) positiveCorrelation bp(HBP:neuroinflammation)
pmid:22890100	p(HGNC:CHI3L1) positiveCorrelation bp(GOBP:"microglial cell activation")
pmid:25024322	p(HGNC:CHI3L1) positiveCorrelation p(HGNC:MAPT)
pmid:25865441	p(HGNC:CHI3L1) positiveCorrelation p(HGNC:MAPT)
pmid:25865441	p(HGNC:CHI3L1) positiveCorrelation p(HGNC:MAPT)
pmid:26836182	p(HGNC:CHI3L1) positiveCorrelation p(HGNC:MAPT)
pmid:26836182	p(HGNC:CHI3L1) positiveCorrelation p(HGNC:MAPT)
pmid:25024322	p(HGNC:CHI3L1) positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:25865441	p(HGNC:CHI3L1) positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:25865441	p(HGNC:CHI3L1) positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:25024322	p(HGNC:CHI3L1) positiveCorrelation a(CTO:"Clinical_Dementia_Rating_Scale-sum_of_boxes")
pmid:25024322	p(HGNC:CHI3L1) positiveCorrelation a(NIFT:"Free and Cued Selective Reminding Test")
pmid:25024322	p(HGNC:CHI3L1) positiveCorrelation a(CTO:"Mini_Mental_State_Examination")
pmid:25681350	p(HGNC:CHI3L1) positiveCorrelation p(HGNC:IL1B)
pmid:25681350	p(HGNC:CHI3L1) positiveCorrelation p(HGNC:IL1B)
pmid:25681350	p(HGNC:CHI3L1) positiveCorrelation p(HGNC:IL6)
pmid:25681350	p(HGNC:CHI3L1) decreases p(HGNC:IL6)
pmid:25865441	p(HGNC:CHI3L1) biomarkerFor path(MESHD:Inflammation)
pmid:21035623	p(HGNC:CHI3L1) positiveCorrelation path(MESHD:Inflammation)
pmid:25865441	p(HGNC:CHI3L1) negativeCorrelation a(NIFT:"Cortical Thickness")
pmid:25865441	p(HGNC:CHI3L1) negativeCorrelation a(NIFT:"Cortical Thickness")
pmid:26836182	p(HGNC:CHI3L1) negativeCorrelation a(NIFT:"Cortical Thickness")
pmid:25865441	p(HGNC:CHI3L1) increases bp(GOBP:"inflammatory response")
pmid:26836182	p(HGNC:CHI3L1) positiveCorrelation p(HGNC:NEFL)
pmid:26836182	p(HGNC:CHI3L1) increases p(HGNC:NEFL)
pmid:26783546	p(HGNC:CHI3L1) positiveCorrelation p(HGNC:NRGN)
pmid:26783546	p(HGNC:CHI3L1) positiveCorrelation p(HGNC:APP, frag("672_711"))
pmid:25681350	p(HGNC:CHI3L1) decreases act(p(HGNC:NFKB1))
pmid:25681350	p(HGNC:CHI3L1) decreases act(p(HGNC:NFKB2))
pmid:25681350	p(HGNC:CHI3L1) increases complex(p(HGNC:ITGB3), p(HGNC:SDC1))
pmid:25681350	p(HGNC:CHI3L1) increases complex(p(HGNC:ITGA5), p(HGNC:SDC1))
pmid:18715507	p(HGNC:DDX39B) increases bp(GOBP:"production of molecular mediator involved in inflammatory response")
pmid:18715507	p(HGNC:DDX39B) increases bp(GOBP:"chemokine biosynthetic process")
pmid:19388207	act(p(HGNC:FPR1)) increases bp(GOBP:"inflammatory response")
pmid:19388207	act(p(HGNC:FPR2)) increases bp(GOBP:"inflammatory response")
pmid:20489155	p(HGNC:GRN) association bp(GOBP:"wound healing")
pmid:20489155	p(HGNC:GRN) association bp(GOBP:"inflammatory response")
pmid:20489155	p(HGNC:GRN) association path(MESHD:Neoplasms)
pmid:20489155	p(HGNC:GRN) increases path(MESHD:"Alzheimer Disease")
pmid:19625741	p(HGNC:GRN) positiveCorrelation bp(GOBP:"neuron death")
pmid:21942811	p(HGNC:ICAM1) biomarkerFor path(MESHD:"Alzheimer Disease")
pmid:22493750	p(HGNC:IL10) association bp(GOBP:"inflammatory response")
pmid:18615183	p(HGNC:IL12B) increases bp(GOBP:"inflammatory response")
pmid:18938162	p(HGNC:IL13) increases p(HGNC:CD200R1)
pmid:20127816	tloc(p(HGNC:IL18), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space")) increases bp(GOBP:"inflammatory response")
pmid:18615183	p(HGNC:IL23A) increases bp(GOBP:"inflammatory response")
pmid:16387846	p(HGNC:IL2RA) association a(CHEBI:simvastatin)
pmid:20127816	tloc(p(HGNC:IL33), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space")) increases bp(GOBP:"inflammatory response")
pmid:18938162	p(HGNC:IL4) increases p(HGNC:CD200R1)
pmid:18941241	act(p(HGNC:IL4)) increases deg(p(HGNC:APP, frag("672_713")))
pmid:18941241	act(p(HGNC:IL4)) positiveCorrelation p(HGNC:IDE)
pmid:18941241	act(p(HGNC:IL4)) positiveCorrelation p(HGNC:MME)
pmid:19556978	p(HGNC:LAMB2) association a(CHEBI:rosiglitazone)
pmid:15255951	p(HGNC:MPO) association path(MESHD:Inflammation)
pmid:15255951	p(HGNC:MPO) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:12946561	p(HGNC:MPO) association path(MESHD:"Alzheimer Disease")
pmid:15255951	p(HGNC:MPO) association bp(MESHPP:"Oxidative Stress")
pmid:15255951	p(HGNC:MPO) increases bp(MESHPP:"Oxidative Stress")
pmid:19059911	p(HGNC:MPO) increases path(MESHD:"Memory Disorders")
pmid:18554520	p(HGNC:MPO) association a(CHEBI:"reactive oxygen species")
pmid:18554520	p(HGNC:MPO) association p(HGNC:TNF)
pmid:19388207	act(p(HGNC:MSR1)) increases bp(GOBP:"inflammatory response")
pmid:22237943	act(p(HGNC:MSR1)) increases a(CHEBI:"nitric oxide")
pmid:18615183	p(HGNC:MYD88) association bp(GOBP:"inflammatory response")
pmid:26836182	p(HGNC:NEFL) positiveCorrelation p(HGNC:CHI3L1)
pmid:24262633	p(HGNC:NFKB2) association act(p(HGNC:NFE2L2))
pmid:18564425	act(p(HGNC:NFKB2), ma(tscript)) increases p(HGNC:APP)
pmid:19388207	act(p(HGNC:NOD2)) increases bp(GOBP:"inflammatory response")
pmid:26783546	p(HGNC:NRGN) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:26783546	p(HGNC:NRGN) positiveCorrelation p(HGNC:CHI3L1)
pmid:26783546	p(HGNC:NRGN) positiveCorrelation p(HGNC:APP, frag("672_711"))
pmid:22406427	tloc(p(HGNC:PLA2G2A), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space")) increases path(MESHD:Inflammation)
pmid:24455696	p(HGNC:PLA2G4A) increases bp(GOBP:"inflammatory response")
pmid:18718604	p(HGNC:PLA2G4A) association bp(MESHPP:"Oxidative Stress")
pmid:20454929	p(HGNC:PLA2G7) increases bp(GOBP:"inflammatory response")
pmid:22493750	p(HGNC:PPARA) association bp(GOBP:"inflammatory response")
pmid:21311715	p(HGNC:PPARA) directlyIncreases g(HGNC:LRP2)
pmid:26113788	p(HGNC:PTPN11) decreases bp(GOBP:"JAK-STAT cascade")
pmid:19388207	act(p(HGNC:PTX3)) increases bp(GOBP:"inflammatory response")
pmid:15474976	p(HGNC:PTX3) positiveCorrelation bp(HBP:neuroinflammation)
pmid:24694234	p(HGNC:RARRES3) association path(MESHD:"Cognitive Dysfunction")
pmid:22237943	p(HGNC:SCARA5) increases bp(GOBP:"inflammatory response")
pmid:22237943	p(HGNC:SCARA5) increases a(CHEBI:"nitric oxide")
pmid:22237943	p(HGNC:SCARB1) increases bp(GOBP:"inflammatory response")
pmid:19388207	act(p(HGNC:SCARB1)) increases bp(GOBP:"inflammatory response")
pmid:22237943	p(HGNC:SCARB1) increases a(CHEBI:"nitric oxide")
pmid:22237943	p(HGNC:SCARF1) increases bp(GOBP:"inflammatory response")
pmid:22237943	p(HGNC:SCARF1) increases a(CHEBI:"nitric oxide")
pmid:26113788	p(HGNC:SOCS1) decreases bp(GOBP:"JAK-STAT cascade")
pmid:26113788	p(HGNC:SOCS3) decreases bp(GOBP:"JAK-STAT cascade")
pmid:19388207	act(p(HGNC:TLR2)) increases bp(GOBP:"inflammatory response")
pmid:18615183	p(HGNC:TLR2) association bp(GOBP:"inflammatory response")
pmid:19149696	p(HGNC:TREM1) increases bp(GOBP:"inflammatory response")
pmid:25027412	p(HGNC:TREM2, var("p.Arg47His")) increases a(NIFT:"Temporal lobe atrophy")
pmid:25027412	p(HGNC:TREM2, var("p.Arg47His")) increases a(NIFT:"Temporal lobe atrophy")
pmid:25027412	p(HGNC:TREM2, var("p.Arg47His")) increases a(NIFT:"Grey matter volume")
pmid:25681350	p(HGNC:TREM2, var("p.Arg47His")) decreases a(MESH:D066128)
pmid:24663666	p(HGNC:TREM2, var("p.Arg47His")) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:24355566	p(HGNC:TREM2, var("p.Arg47His")) increases bp(GOBP:"negative regulation of phagocytosis")
pmid:24355566	p(HGNC:TREM2, var("p.Arg47His")) decreases bp(GOBP:"regulation of inflammatory response")
pmid:17005052	p(MGI:App, var("p.Asp23Asn"), var("p.Glu22Gln")) increases r(MGI:Tnf)
pmid:17005052	p(MGI:App, var("p.Lys670Asn"), var("p.Met671Leu")) increases r(MGI:Arg1)
pmid:17005052	p(MGI:App, var("p.Lys670Asn"), var("p.Met671Leu")) increases r(MGI:Mrc1)
pmid:17005052	p(MGI:App, var("p.Lys670Asn"), var("p.Met671Leu")) increases r(MGI:Chil3)
pmid:11755016	p(MGI:Cd40lg) increases p(HGNC:APP, frag("672_713"))
pmid:11755016	p(MGI:Cd40lg) increases bp(GOBP:"inflammatory response")
pmid:23650073	p(MGI:Hmgb1) increases bp(GOBP:"inflammatory response")
pmid:23468966	p(MGI:Il17a) association path(MESHD:Inflammation)
pmid:23650073	p(MGI:Il6) increases bp(GOBP:"inflammatory response")
pmid:20937084	p(MGI:Kng1) decreases p(MGI:Nos2)
pmid:20937084	p(MGI:Kng1) decreases p(MGI:Ptgs2)
pmid:22441986	p(MGI:Lcn2) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22441986	p(MGI:Lcn2) increases bp(HBP:neuroinflammation)
pmid:8879214	p(MGI:Nos2) negativeCorrelation p(MGI:Tgfb1)
pmid:24854197	p(MGI:Nos2) decreases p(HGNC:IL32)
pmid:10417811	p(MGI:Pla2g4a) increases bp(GOBP:"inflammatory response")
pmid:10417811	act(p(MGI:Pla2g4a)) increases deg(a(CHEBI:phospholipid))
pmid:10417811	act(p(MGI:Pla2g4a)) increases a(CHEBI:icosanoid)
pmid:20937084	p(MGI:Sst) association path(MESHD:Inflammation)
pmid:22198949	p(MGI:Tlr1) increases bp(GOBP:"inflammatory response")
pmid:22198949	p(MGI:Tlr6) decreases bp(GOBP:"inflammatory response")
pmid:20937084	p(SFAM:"EDN Family") association path(MESHD:Inflammation)
pmid:20937084	p(SFAM:"EDN Family") decreases r(MGI:Ccl2)
pmid:20937084	p(SFAM:"EDN Family") decreases r(MGI:Il6)
pmid:22441986	p(SFAM:"TNFRSF Family") association p(HGNC:TNF)
pmid:18637012	path(HP:"Brain atrophy") negativeCorrelation bp(GOBP:"inflammatory response")
pmid:24262633	path(MESHD:"Brain Injuries, Traumatic") association p(HGNC:NFE2L2)
pmid:24262633	path(MESHD:"Brain Injuries, Traumatic") negativeCorrelation p(HGNC:NFE2L2)
pmid:24863743	path(MESHD:"Brain Injuries, Traumatic") positiveCorrelation bp(HBP:neuroinflammation)
pmid:18554520	path(MESHD:"Multiple Sclerosis") association path(MESHD:Inflammation)
pmid:24863743	path(MESHD:"Multiple Sclerosis") positiveCorrelation bp(HBP:neuroinflammation)
pmid:20660113	path(MESHD:"Nerve Degeneration") association p(HGNC:MAPT, pmod(Ph))
pmid:12668899	path(MESHD:"Nerve Degeneration") association a(CHEBI:cholesterol)
pmid:14976144	path(MESHD:"Nerve Degeneration") association act(p(HGNC:CDK5))
pmid:20489155	path(MESHD:Neoplasms) association p(HGNC:GRN)
pmid:18938162	r(HGNC:CD200) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:18938162	r(HGNC:CD200R1) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:20489155	r(HGNC:GRN) association m(HGNC:MIR107)
pmid:20489155	r(HGNC:GRN) increases p(HGNC:GRN)
pmid:19625741	r(HGNC:GRN) increases p(HGNC:GRN)
pmid: 21047645	r(HGNC:GRN) association g(DBSNP:rs5848)
pmid:14699072	r(HGNC:IL4R) association a(CHEBI:raloxifene)
pmid:20937840	r(HGNC:IRAK1) decreases bp(GOBP:"inflammatory response")
pmid:22209051	r(HGNC:IRAK1) association m(HGNC:MIR146A)
pmid:20937840	r(HGNC:IRAK2) increases bp(GOBP:"inflammatory response")
pmid:20044591	r(HGNC:LAMB2) association a(CHEBI:"hydrogen peroxide")
pmid:20044591	r(HGNC:LAMC2) association a(CHEBI:"hydrogen peroxide")
pmid:22209051	r(HGNC:TRAF6) association m(HGNC:MIR146A)
pmid:22209051	r(HGNC:TRAF6) increases p(HGNC:TRAF6)
pmid:23073831	a(CHEBI:"1D-chiro-inositol") increases bp(MESH:D000066829)
pmid:24652830	a(CHEBI:"2-deoxy-2-((18)F)fluoro-D-glucopyranose") negativeCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:24652830	a(CHEBI:"2-deoxy-2-((18)F)fluoro-D-glucopyranose") positiveCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:24652830	a(CHEBI:"2-deoxy-2-((18)F)fluoro-D-glucopyranose") positiveCorrelation bp(GOBP:"glucose import")
pmid:19573562	a(CHEBI:"exendin-4") isA a(CHEBI:"glucagon-like peptide-1 receptor agonist")
pmid:19573562	a(CHEBI:"exendin-4") decreases path(MESHD:"Diabetes Mellitus, Type 2")
pmid:22443187	a(CHEBI:"exendin-4") decreases path(MESHD:"Diabetes Mellitus, Type 2")
pmid:22443187	a(CHEBI:"exendin-4") increases bp(GOBP:"insulin receptor signaling pathway")
pmid:19573562	a(CHEBI:"glucagon-like peptide-1 receptor agonist") directlyIncreases act(p(HGNC:GLP1R))
pmid:24881967	a(CHEBI:"insulin (human)") decreases path(MESHD:"Memory Disorders")
pmid:24881967	a(CHEBI:"insulin (human)") decreases act(p(RGD:Casp3))
pmid:24881967	a(CHEBI:"insulin (human)") decreases act(p(SFAM:"MAPK Erk1/2 Family"))
pmid:22536436	a(CHEBI:"insulin (human)") increases p(SFAM:"AKT Family", pmod(Ph))
pmid:15283963	a(CHEBI:"insulin (human)") association act(p(HGNC:AKT1), ma(kin))
pmid:19885299	a(CHEBI:"insulin-sensitizing drug") decreases path(MESHD:"Diabetes Mellitus, Experimental")
pmid:19885299	a(CHEBI:"insulin-sensitizing drug") decreases path(MESHD:"Diabetes Mellitus, Type 2")
pmid:19885299	a(CHEBI:"insulin-sensitizing drug") decreases bp(MESHPP:"Insulin Resistance")
pmid:18941241	a(CHEBI:Thiorphan) decreases p(HGNC:MME)
pmid:18941241	a(CHEBI:Thiorphan) decreases act(p(HGNC:IL4))
pmid:20471460	a(CHEBI:crotonaldehyde) decreases r(HGNC:LNPEP)
pmid:22536436	a(CHEBI:glucocorticoid) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22536436	a(CHEBI:glucocorticoid) positiveCorrelation bp(MESHPP:"Insulin Resistance")
pmid:19383491	a(CHEBI:glucocorticoid) increases bp(MESHPP:"Insulin Resistance")
pmid:22536436	a(CHEBI:glucocorticoid) association p(HGNC:MAPT, pmod(Ph))
pmid:22536436	a(CHEBI:glucocorticoid) association act(p(HGNC:CAPN1))
pmid:14976144	a(CHEBI:glucose) increases act(g(HGNC:CDK5R1))
pmid:14976144	a(CHEBI:glucose) increases complex(p(HGNC:CDK5), p(HGNC:CDK5R1))
pmid:14976144	a(CHEBI:glucose) regulates act(g(HGNC:INS))
pmid:14976144	a(CHEBI:glucose) regulates act(g(HGNC:PDX1))
pmid:14976144	a(CHEBI:glucose) regulates act(g(HGNC:IAPP))
pmid:14976144	a(CHEBI:glucose) regulates act(g(HGNC:SLC2A2))
pmid:21352095	a(CHEBI:glucose) association bp(GOBP:"amyloid precursor protein metabolic process")
pmid:23954639	a(CHEBI:glucose) decreases act(p(HGNC:PRKAA2))
pmid:22443187	a(CHEBI:liraglutide) isA a(CHEBI:"glucagon-like peptide-1 receptor agonist")
pmid:22443187	a(CHEBI:liraglutide) decreases path(MESHD:"Diabetes Mellitus, Type 2")
pmid:22443187	a(CHEBI:liraglutide) increases bp(GOBP:"insulin receptor signaling pathway")
pmid:22443187	a(CHEBI:liraglutide) increases a(CHEBI:"3',5'-cyclic AMP")
pmid:22443187	a(CHEBI:lixisenatide) isA a(CHEBI:"glucagon-like peptide-1 receptor agonist")
pmid:22443187	a(CHEBI:lixisenatide) increases a(CHEBI:"3',5'-cyclic AMP")
pmid:19519303	a(CHEBI:nutrient) negativeCorrelation path(MESHD:"Glucose Intolerance")
pmid:14976144	a(CHEBI:seliciclib) directlyDecreases act(p(HGNC:CDK5))
pmid:14976144	a(CHEBI:seliciclib) decreases complex(p(HGNC:CDK5), p(HGNC:CDK5R1))
pmid:17329077	a(CHEBI:trichlorfon) decreases r(HGNC:STAR)
pmid:14976144	a(GOCC:cell) positiveCorrelation g(HGNC:ENO1)
pmid:14976144	a(GOCC:cell) positiveCorrelation p(HGNC:VAMP2)
pmid:14976144	a(GOCC:cell) positiveCorrelation a(HBP:"A2B5 antigen")
pmid:14976144	a(GOCC:cell) positiveCorrelation act(g(HGNC:INS))
pmid:14976144	a(GOCC:cell) positiveCorrelation act(g(HGNC:PDX1))
pmid:14976144	a(GOCC:cell) positiveCorrelation act(g(HGNC:ISL1))
pmid:14976144	a(GOCC:cell) positiveCorrelation act(p(HGNC:CDK5R1))
pmid:14976144	a(GOCC:cell) positiveCorrelation act(complex(p(HGNC:CDK5), p(HGNC:CDK5R1)))
pmid:19885299	a(GOCC:cytoskeleton) positiveCorrelation p(HGNC:INS)
pmid:19885299	a(GOCC:cytoskeleton) positiveCorrelation p(HGNC:IGF1)
pmid:19885299	a(GOCC:cytoskeleton) negativeCorrelation bp(MESHPP:"Insulin Resistance")
pmid:14976144	a(HBP:"A2B5 antigen") positiveCorrelation a(MESH:D050417)
pmid:14976144	a(HBP:"A2B5 antigen") positiveCorrelation a(GOCC:cell)
pmid:19188609	act(a(HBP:"amyloid-beta derived diffusible ligands")) increases complex(a(HBP:"amyloid-beta derived diffusible ligands"), p(HGNC:INSR))
pmid:14976144	a(MESH:D050417) positiveCorrelation g(HGNC:ENO1)
pmid:14976144	a(MESH:D050417) positiveCorrelation p(HGNC:VAMP2)
pmid:14976144	a(MESH:D050417) positiveCorrelation a(HBP:"A2B5 antigen")
pmid:14976144	act(a(MESH:D050417)) association act(g(HGNC:INS))
pmid:14976144	act(a(MESH:D050417)) association act(g(HGNC:PDX1))
pmid:14976144	act(a(MESH:D050417)) association act(g(HGNC:IAPP))
pmid:14976144	act(a(MESH:D050417)) association act(g(HGNC:SLC2A2))
pmid:22321797	deg(a(MESH:D050417)) association tloc(p(HGNC:IAPP), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:23789959	bp(GO:"GO:0097242") association p(HGNC:ABCB1)
pmid:23789959	bp(GO:"GO:0097242") association p(HGNC:ABCG2)
pmid:23789959	bp(GO:"GO:0097242") association p(HGNC:ABCC1)
pmid:14678766	bp(GO:"GO:0097242") association p(HGNC:A2M)
pmid:19519303	bp(GOBP:"activation of MAPKK activity") increases bp(GOBP:"ERK1 and ERK2 cascade")
pmid:16399206	bp(GOBP:"amyloid precursor protein catabolic process") association p(HGNC:INS)
pmid:19519303	bp(GOBP:"energy homeostasis") positiveCorrelation act(p(HGNC:INS))
pmid:19519303	bp(GOBP:"energy homeostasis") positiveCorrelation act(p(HGNC:IGF1))
pmid:15094078	bp(GOBP:"energy homeostasis") positiveCorrelation bp(GOBP:"insulin receptor signaling pathway")
pmid:16444902	bp(GOBP:"glucose catabolic process") association p(HGNC:IGF1)
pmid:16444902	bp(GOBP:"glucose homeostasis") association p(HGNC:IGF1)
pmid:19519303	bp(GOBP:"glucose import") association act(p(HGNC:INS))
pmid:19519303	bp(GOBP:"glucose import") association act(p(HGNC:IGF1))
pmid:24652830	bp(GOBP:"glucose import") positiveCorrelation a(CHEBI:"2-deoxy-2-((18)F)fluoro-D-glucopyranose")
pmid:19519303	bp(GOBP:"negative regulation of insulin receptor signaling pathway") increases p(HGNC:MAPT, pmod(Ph))
pmid:16399206	bp(GOBP:"negative regulation of insulin receptor signaling pathway") association p(HGNC:MAPT, pmod(Ph))
pmid:19885299	bp(GOBP:"negative regulation of insulin-like growth factor receptor signaling pathway") association path(MESHD:"Alzheimer Disease")
pmid:19519303	bp(GOBP:"negative regulation of insulin-like growth factor receptor signaling pathway") increases p(HGNC:MAPT, pmod(Ph))
pmid:11956956	bp(GOBP:"regulation of ATPase activity") association act(p(HGNC:INS))
pmid:23627755	bp(GOBP:"regulation of amyloid precursor protein catabolic process") association p(HGNC:INS)
pmid:17316694	bp(GOBP:"regulation of insulin receptor signaling pathway") negativeCorrelation bp(GOBP:"glucose metabolic process")
pmid:19519303	bp(GOBP:"regulation of insulin-like growth factor receptor signaling pathway") association p(HGNC:APP, frag("672_713"))
pmid:19519303	bp(GOBP:"regulation of insulin-like growth factor receptor signaling pathway") increases bp(GOBP:"neurotrophin production")
pmid:19519303	bp(GOBP:"regulation of protein tyrosine kinase activity") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19188609	bp(GOBP:"regulation of protein tyrosine kinase activity") association p(HGNC:INSR)
pmid:19188609	bp(GOBP:"regulation of protein tyrosine kinase activity") increases act(p(HGNC:INS))
pmid:19519303	bp(GOBP:"response to insulin") association a(CHEBI:estrogen)
pmid:21537460	bp(GOBP:"type B pancreatic cell proliferation") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:21537460	bp(GOBP:"type B pancreatic cell proliferation") negativeCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:16399206	bp(GOBP:aging) negativeCorrelation act(p(HGNC:IDE))
pmid:22524398	bp(GOBP:aging) decreases p(HGNC:IGF1)
pmid:22079549	bp(GOBP:aging) decreases p(HGNC:NOS3)
pmid:22079549	bp(GOBP:aging) increases deg(a(CHEBI:"nitric oxide"))
pmid:22079549	bp(GOBP:aging) decreases bp(GOBP:"regulation of nitric-oxide synthase activity")
pmid:22079549	bp(GOBP:aging) increases a(CHEBI:"reactive oxygen species")
pmid:22079549	bp(GOBP:aging) decreases bp(GOBP:"regulation of telomerase activity")
pmid:19885299	bp(HBP:"mitochondrial dysfunction") positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:19885299	bp(HBP:"mitochondrial dysfunction") negativeCorrelation bp(GOBP:"insulin-like growth factor receptor signaling pathway")
pmid:19885299	bp(HBP:"mitochondrial dysfunction") increases g(HGNC:APP)
pmid:19885299	bp(HBP:"mitochondrial dysfunction") increases rxn(reactants(p(HGNC:APP)), products(p(HGNC:APP, frag("672_713"))))
pmid:19885299	bp(MESHPP:"Polymorphism, Single Nucleotide") association g(HGNC:INSR)
pmid:19885299	bp(MESHPP:"Polymorphism, Single Nucleotide") association g(HGNC:INPPL1)
pmid:19885299	bp(MESHPP:"Polymorphism, Single Nucleotide") association g(HGNC:HK2)
pmid:19885299	bp(MESHPP:"Polymorphism, Single Nucleotide") association g(HGNC:NOS3)
pmid:19519303	bp(MESHPP:Longevity) association act(p(HGNC:INS))
pmid:19519303	bp(MESHPP:Longevity) association act(p(HGNC:IGF1))
pmid:19519303	bp(MESHPP:Longevity) negativeCorrelation bp(GOBP:"insulin receptor signaling pathway")
pmid:19519303	bp(MESHPP:Longevity) association p(HGNC:IRS1)
pmid:19519303	bp(MESHPP:Longevity) positiveCorrelation p(HGNC:CAT)
pmid:19519303	bp(MESHPP:Longevity) positiveCorrelation p(HGNC:SOD1)
pmid:19519303	bp(MESHPP:Obesity) positiveCorrelation bp(MESHPP:"Insulin Resistance")
pmid:19383491	act(complex(GOCC:"NMDA selective glutamate receptor complex")) increases bp(MESHPP:"Long-Term Potentiation")
pmid:22496686	act(complex(GOCC:"NMDA selective glutamate receptor complex")) association bp(GOBP:"calcium ion import")
pmid:21598254	complex(GOCC:"phosphatidylinositol 3-kinase complex") association bp(GOBP:"insulin receptor signaling pathway via phosphatidylinositol 3-kinase")
pmid:21598254	complex(GOCC:"phosphatidylinositol 3-kinase complex") negativeCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:21598254	complex(GOCC:"phosphatidylinositol 3-kinase complex") positiveCorrelation act(p(HGNC:OGT))
pmid:19188609	complex(p(HGNC:ADD3), p(HGNC:INS)) decreases act(p(HGNC:ADD3))
pmid:19188609	p(HGNC:ADD3) increases bp(MESHPP:"Oxidative Stress")
pmid:19188609	act(p(HGNC:ADD3)) negativeCorrelation p(HGNC:INSR)
pmid:19188609	complex(p(HGNC:ADD3), p(HGNC:INSR)) negativeCorrelation tloc(p(HGNC:INSR), fromLoc(GOCC:intracellular), toLoc(GOCC:"cell surface"))
pmid:18411275	complex(p(HGNC:APP, frag("672_713")), p(HGNC:IDE)) association path(MESHD:"Alzheimer Disease")
pmid:19519303	act(p(HGNC:IDE)) increases deg(p(HGNC:APP, frag("672_713")))
pmid:16399206	act(p(HGNC:IDE)) increases deg(p(HGNC:APP, frag("672_713")))
pmid:16399206	act(p(HGNC:IDE)) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:18411275	p(HGNC:IDE) association deg(p(HGNC:APP, frag("672_713")))
pmid:19383491	p(HGNC:IDE) increases deg(p(HGNC:APP, frag("672_713")))
pmid:22227962	act(p(HGNC:IDE)) increases deg(p(HGNC:APP, frag("672_713")))
pmid:19355846	p(HGNC:IDE) decreases p(HGNC:APP, frag("672_713"))
pmid:16399206	act(p(HGNC:IDE)) negativeCorrelation bp(GOBP:aging)
pmid:16399206	act(p(HGNC:IDE)) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19383491	p(HGNC:IDE) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:16399206	act(p(HGNC:IDE)) increases deg(a(CHEBI:"amyloid-beta"))
pmid:25999473	p(HGNC:IDE) increases deg(a(CHEBI:"amyloid-beta"))
pmid:18411275	p(HGNC:IDE) association deg(p(HGNC:INS))
pmid:15590928	p(HGNC:IDE) increases deg(p(HGNC:INS))
pmid:19383491	p(HGNC:IDE) increases deg(p(HGNC:INS))
pmid:18941241	p(HGNC:IDE) positiveCorrelation act(p(HGNC:IL4))
pmid:19383491	p(HGNC:IDE) negativeCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:22227962	act(p(HGNC:IDE)) negativeCorrelation p(HGNC:NOS2)
pmid:15094078	complex(p(HGNC:APP, frag("672_713")), p(HGNC:INSR)) decreases act(p(HGNC:INSR))
pmid:20847424	complex(p(HGNC:APP, frag("672_713")), p(HGNC:INSR)) increases act(p(HGNC:PDK1))
pmid:19519303	complex(p(HGNC:GAB1), p(HGNC:GRB2)) increases complex(p(HGNC:GAB1), p(HGNC:GRB2), p(HGNC:SOS1))
pmid:19519303	complex(p(HGNC:GAB1), p(HGNC:GRB2), p(HGNC:SOS1)) increases act(p(SFAM:"RAS Family"), ma(gtp))
pmid:19519303	complex(p(HGNC:GAB1), p(HGNC:GRB2), p(HGNC:SOS1)) increases tloc(p(HGNC:RAF1), fromLoc(GOCC:cytosol), toLoc(GOCC:membrane))
pmid:19519303	p(HGNC:IRS1, pmod(Ph, Tyr)) increases complex(p(HGNC:IRS1, pmod(Ph, Tyr)), p(HGNC:PIK3R1))
pmid:19519303	p(HGNC:IRS1, pmod(Ph, Tyr)) increases complex(p(HGNC:IRS1, pmod(Ph, Tyr)), p(HGNC:PIK3R2))
pmid:19519303	p(HGNC:IRS1, pmod(Ph, Tyr)) increases complex(p(HGNC:GRB2), p(HGNC:IRS1, pmod(Ph, Tyr)))
pmid:19519303	p(HGNC:IRS1, pmod(Ph, Tyr)) increases complex(p(HGNC:IRS1, pmod(Ph, Tyr)), p(HGNC:PTPN11))
pmid:19519303	p(HGNC:IRS2, pmod(Ph, Tyr)) increases complex(p(HGNC:IRS2, pmod(Ph, Tyr)), p(HGNC:PIK3R1))
pmid:19519303	p(HGNC:IRS2, pmod(Ph, Tyr)) increases complex(p(HGNC:IRS2, pmod(Ph, Tyr)), p(HGNC:PIK3R2))
pmid:19519303	p(HGNC:IRS2, pmod(Ph, Tyr)) increases complex(p(HGNC:GRB2), p(HGNC:IRS2, pmod(Ph, Tyr)))
pmid:19519303	p(HGNC:IRS2, pmod(Ph, Tyr)) increases complex(p(HGNC:IRS2, pmod(Ph, Tyr)), p(HGNC:PTPN11))
pmid:19519303	p(HGNC:IRS4, pmod(Ph, Tyr)) increases complex(p(HGNC:IRS4, pmod(Ph, Tyr)), p(HGNC:PIK3R1))
pmid:19519303	p(HGNC:IRS4, pmod(Ph, Tyr)) increases complex(p(HGNC:IRS4, pmod(Ph, Tyr)), p(HGNC:PIK3R2))
pmid:19519303	p(HGNC:IRS4, pmod(Ph, Tyr)) increases complex(p(HGNC:GRB2), p(HGNC:IRS4, pmod(Ph, Tyr)))
pmid:19519303	p(HGNC:IRS4, pmod(Ph, Tyr)) increases complex(p(HGNC:IRS4, pmod(Ph, Tyr)), p(HGNC:PTPN11))
pmid:19519303	complex(p(HGNC:GRB2), p(SFAM:"IRS Family")) increases complex(p(HGNC:GAB1), p(HGNC:GRB2), p(HGNC:SOS1))
pmid:19519303	p(SFAM:"IRS Family") increases act(complex(GOCC:"phosphatidylinositol 3-kinase complex"))
pmid:19519303	p(SFAM:"IRS Family") increases act(p(SFAM:"MAPK Erk1/2 Family"))
pmid:21916834	p(SFAM:"IRS Family") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:20847424	act(complex(p(HGNC:GSK3A), p(HGNC:PDPK1), p(HGNC:PIK3R5))) increases bp(GOBP:"glucose metabolic process")
pmid:20847424	act(complex(p(HGNC:GSK3A), p(HGNC:PDPK1), p(HGNC:PIK3R5))) increases bp(GOBP:"energy reserve metabolic process")
pmid:20847424	act(complex(p(HGNC:GSK3A), p(HGNC:PDPK1), p(HGNC:PIK3R5))) increases bp(GOBP:"negative regulation of neuron apoptotic process")
pmid:20847424	act(complex(p(HGNC:GSK3B), p(HGNC:PDPK1), p(HGNC:PIK3R5))) increases bp(GOBP:"glucose metabolic process")
pmid:20847424	act(complex(p(HGNC:GSK3B), p(HGNC:PDPK1), p(HGNC:PIK3R5))) increases bp(GOBP:"energy reserve metabolic process")
pmid:20847424	act(complex(p(HGNC:GSK3B), p(HGNC:PDPK1), p(HGNC:PIK3R5))) increases bp(GOBP:"negative regulation of neuron apoptotic process")
pmid:19519303	complex(p(HGNC:IGF1), p(HGNC:IGF1R), p(HGNC:INSR)) increases bp(GOBP:"regulation of protein tyrosine kinase activity")
pmid:19885299	p(HGNC:IGF2) negativeCorrelation path(MESHD:Dementia)
pmid:19885299	p(HGNC:IGF2) negativeCorrelation act(a(MESH:D001253))
pmid:19885299	p(HGNC:IGF2) negativeCorrelation act(a(MESH:D017628))
pmid:24324435	p(HGNC:IGF2) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:19519303	complex(p(HGNC:IGF1R), p(HGNC:INS), p(HGNC:INSR)) increases bp(GOBP:"regulation of protein tyrosine kinase activity")
pmid:19519303	complex(p(HGNC:IGF1R), p(HGNC:INSR)) increases complex(p(HGNC:IGF1), p(HGNC:IGF1R), p(HGNC:INSR))
pmid:19519303	complex(p(HGNC:IGF1R), p(HGNC:INSR)) increases complex(p(HGNC:IGF1R), p(HGNC:IGF2), p(HGNC:INSR))
pmid:19519303	complex(p(HGNC:IGF1R), p(HGNC:INSR)) increases complex(p(HGNC:IGF1R), p(HGNC:INS), p(HGNC:INSR))
pmid:19519303	complex(p(HGNC:IGF1R, pmod(Ph, Tyr)), p(HGNC:INSR)) increases p(HGNC:IRS1, pmod(Ph, Tyr))
pmid:19519303	complex(p(HGNC:IGF1R, pmod(Ph, Tyr)), p(HGNC:INSR)) increases p(HGNC:IRS2, pmod(Ph, Tyr))
pmid:19519303	complex(p(HGNC:IGF1R, pmod(Ph, Tyr)), p(HGNC:INSR)) increases p(HGNC:IRS4, pmod(Ph, Tyr))
pmid:12185156	p(HGNC:PIK3R1) association p(SFAM:"INS Family")
pmid:19519303	g(DBSNP:rs1801278) association p(HGNC:IRS1, var("p.Gly972Arg"))
pmid:23279143	g(DBSNP:rs7907690) association g(HGNC:SORCS1)
pmid:23279143	g(DBSNP:rs7907690) association path(MESHD:"Alzheimer Disease")
pmid:23279143	g(DBSNP:rs7907690) association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:14976144	g(HGNC:ENO1) positiveCorrelation a(MESH:D050417)
pmid:14976144	g(HGNC:ENO1) positiveCorrelation a(GOCC:cell)
pmid:19885299	g(HGNC:ENPP1) association path(MESHD:"Alzheimer Disease")
pmid:19885299	g(HGNC:HK2) association bp(MESHPP:"Polymorphism, Single Nucleotide")
pmid:14976144	act(g(HGNC:IAPP)) association act(a(MESH:D050417))
pmid:19885299	g(HGNC:INPPL1) association bp(MESHPP:"Polymorphism, Single Nucleotide")
pmid:14976144	act(g(HGNC:INS)) positiveCorrelation a(GOCC:cell)
pmid:14976144	act(g(HGNC:INS)) association act(a(MESH:D050417))
pmid:19885299	g(HGNC:INSR) association path(MESHD:"Alzheimer Disease")
pmid:19885299	g(HGNC:INSR) association bp(MESHPP:"Polymorphism, Single Nucleotide")
pmid:14976144	act(g(HGNC:ISL1)) positiveCorrelation a(GOCC:cell)
pmid:17440948	g(HGNC:PCK1) association bp(GOBP:"insulin receptor signaling pathway")
pmid:14976144	act(g(HGNC:PDX1)) positiveCorrelation a(GOCC:cell)
pmid:14976144	act(g(HGNC:PDX1)) association act(a(MESH:D050417))
pmid:14976144	act(g(HGNC:SLC2A2)) association act(a(MESH:D050417))
pmid:23279143	g(HGNC:SORCS1) association g(DBSNP:rs7907690)
pmid:22046233	g(HGNC:SORCS1) directlyDecreases g(HGNC:PSEN1)
pmid:22046233	g(HGNC:SORCS1) directlyDecreases p(HGNC:APP, frag("672_713"))
pmid:17440948	g(HGNC:SOS2) association bp(GOBP:"insulin receptor signaling pathway")
pmid:22236693	g(RGD:Ngfr) association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:17049785	p(HGNC:AKT1, pmod(Ph)) association bp(PTS:"Insulin receptor signaling pathway")
pmid:22536436	p(HGNC:AKT1, pmod(Ph, Ser, 473)) biomarkerFor bp(MESHPP:"Insulin Resistance")
pmid:17120162	act(p(HGNC:CAMK2A), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:22536436	act(p(HGNC:CAPN1)) increases path(MESHD:"Alzheimer Disease")
pmid:22536436	act(p(HGNC:CAPN1)) association bp(MESHPP:"Insulin Resistance")
pmid:22536436	act(p(HGNC:CAPN1)) association a(CHEBI:glucocorticoid)
pmid:21598254	act(p(HGNC:CAPN1)) negativeCorrelation bp(GOBP:"insulin receptor signaling pathway via phosphatidylinositol 3-kinase")
pmid:21598254	p(HGNC:CAPN1) decreases bp(GOBP:"insulin receptor signaling pathway via phosphatidylinositol 3-kinase")
pmid:22536436	act(p(HGNC:CAPN1)) decreases p(SFAM:"AKT Family", pmod(Ph))
pmid:23603201	p(HGNC:DPP4) negativeCorrelation p(HGNC:GCG)
pmid:23579020	p(HGNC:DPP4) increases deg(p(HGNC:APP, frag("672_713")))
pmid:23579020	p(HGNC:DPP4) increases deg(p(HGNC:APP, frag("672_711")))
pmid:23579020	p(HGNC:DPP4) decreases complex(GOCC:"neurofibrillary tangle")
pmid:19519303	act(p(HGNC:ECE1)) increases deg(p(HGNC:APP, frag("672_713")))
pmid:19519303	p(HGNC:FOXO1) increases bp(GOBP:"insulin receptor signaling pathway")
pmid:19519303	tloc(p(HGNC:FOXO1, pmod(Ph)), fromLoc(GOCC:intracellular), toLoc(GOCC:nucleus)) association bp(GOBP:"insulin-like growth factor receptor signaling pathway")
pmid:19519303	p(HGNC:FOXO3) increases bp(GOBP:"insulin receptor signaling pathway")
pmid:19519303	p(HGNC:FOXO3) decreases p(HGNC:IGF1)
pmid:19519303	p(HGNC:FOXO4) increases bp(GOBP:"insulin receptor signaling pathway")
pmid:21321400	act(p(HGNC:HEXB)) association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:21321400	act(p(HGNC:HEXB)) association path(MESHD:"Alzheimer Disease")
pmid:21321400	act(p(HGNC:HEXB)) association path(MESHD:Dementia)
pmid:21872563	p(HGNC:HMOX1) decreases bp(GOBP:"response to oxidative stress")
pmid:18941241	p(HGNC:HSPA1B) increases deg(p(HGNC:APP, frag("672_713")))
pmid:16887805	p(HGNC:HSPA1B) increases bp(GOBP:"oxidative phosphorylation")
pmid:16399206	p(HGNC:IDE, pmod(Ub)) decreases act(p(HGNC:IDE))
pmid:24324435	p(HGNC:IGFBP2) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:21872563	p(HGNC:IL34) increases p(HGNC:IDE)
pmid:21872563	p(HGNC:IL34) increases p(HGNC:HMOX1)
pmid:21872563	p(HGNC:IL34) decreases bp(GOBP:"response to oxidative stress")
pmid:19519303	p(HGNC:IRS1, pmod(Ph, Ser, 312)) decreases act(p(HGNC:IRS1))
pmid:19605645	p(HGNC:IRS1, pmod(Ph, Ser, 312)) positiveCorrelation deg(p(HGNC:IRS1))
pmid:19519303	p(HGNC:IRS1, pmod(Ph, Ser, 312)) negativeCorrelation bp(GOBP:"insulin receptor signaling pathway")
pmid:19519303	p(HGNC:IRS1, pmod(Ph, Ser, 312)) negativeCorrelation bp(GOBP:"insulin-like growth factor receptor signaling pathway")
pmid:19519303	p(HGNC:IRS1, pmod(Ph, Ser, 616)) decreases act(p(HGNC:IRS1))
pmid:19519303	p(HGNC:IRS1, pmod(Ph, Ser, 616)) negativeCorrelation bp(GOBP:"insulin-like growth factor receptor signaling pathway")
pmid:20847424	p(HGNC:IRS1, pmod(Ph, Thr)) association act(a(MESHC:Cytokines))
pmid:20847424	act(p(HGNC:IRS1, pmod(Ph, Thr))) association p(HGNC:PIK3R5)
pmid:20847424	act(p(HGNC:IRS1, pmod(Ph, Thr))) increases act(p(HGNC:PDPK1))
pmid:20847424	act(p(HGNC:IRS1, pmod(Ph, Thr))) association p(HGNC:GRB2)
pmid:20847424	act(p(HGNC:IRS1, pmod(Ph, Thr))) increases act(p(HGNC:GSK3A))
pmid:20847424	act(p(HGNC:IRS1, pmod(Ph, Thr))) increases act(p(SFAM:"MAPK JNK Family"))
pmid:20847424	p(HGNC:IRS1, pmod(Ph, Thr)) increases composite(p(SFAM:"AKT Family"), p(SFAM:"PIK3C Class IA Family"))
pmid:19519303	p(HGNC:IRS1, var("p.Gly972Arg")) association bp(MESHPP:"Insulin Resistance")
pmid:19519303	p(HGNC:IRS1, var("p.Gly972Arg")) association g(DBSNP:rs1801278)
pmid:19519303	p(HGNC:IRS1, var("p.Gly972Arg")) association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:20847424	p(HGNC:IRS2, pmod(Ph, Thr)) association act(a(MESHC:Cytokines))
pmid:20847424	act(p(HGNC:IRS2, pmod(Ph, Thr))) association p(HGNC:PIK3R5)
pmid:20847424	act(p(HGNC:IRS2, pmod(Ph, Thr))) increases act(p(HGNC:PDPK1))
pmid:20847424	act(p(HGNC:IRS2, pmod(Ph, Thr))) association p(HGNC:GRB2)
pmid:20847424	act(p(HGNC:IRS2, pmod(Ph, Thr))) increases act(p(HGNC:GSK3B))
pmid:20847424	act(p(HGNC:IRS2, pmod(Ph, Thr))) increases act(p(HGNC:GSK3A))
pmid:20847424	act(p(HGNC:IRS2, pmod(Ph, Thr))) increases act(p(SFAM:"MAPK JNK Family"))
pmid:20847424	p(HGNC:IRS2, pmod(Ph, Thr)) increases composite(p(SFAM:"AKT Family"), p(SFAM:"PIK3C Class IA Family"))
pmid:19659459	p(HGNC:MAPT, pmod(OGlyco)) negativeCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:19659459	p(HGNC:MAPT, pmod(OGlyco)) decreases p(HGNC:MAPT, pmod(Ph))
pmid:21598254	act(p(HGNC:OGT)) positiveCorrelation p(HGNC:AKT1)
pmid:21598254	act(p(HGNC:OGT)) positiveCorrelation p(HGNC:INS)
pmid:21598254	act(p(HGNC:OGT)) positiveCorrelation complex(GOCC:"phosphatidylinositol 3-kinase complex")
pmid:19659459	act(p(HGNC:OGT)) negativeCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:19659459	act(p(HGNC:OGT)) increases p(HGNC:MAPT, pmod(OGlyco))
pmid:12185156	p(HGNC:PIK3R1, var("p.Met326Ile")) association path(MESHD:"Alzheimer Disease")
pmid:12185156	p(HGNC:PIK3R1, var("p.Met326Ile")) increases bp(MESHPP:"Insulin Resistance")
pmid:12185156	p(HGNC:PPP1R3A) association p(SFAM:"INS Family")
pmid:12185156	p(HGNC:PPP1R3A, var("p.Asn905Tyr")) increases bp(MESHPP:"Insulin Resistance")
pmid:19519303	act(p(HGNC:RAF1)) increases bp(GOBP:"activation of MAPKK activity")
pmid:20847424	p(HGNC:SHC1, pmod(Ph, Thr)) association act(a(MESHC:Cytokines))
pmid:20847424	p(HGNC:SHC2, pmod(Ph, Thr)) association act(a(MESHC:Cytokines))
pmid:20847424	p(HGNC:SHC3, pmod(Ph, Thr)) association act(a(MESHC:Cytokines))
pmid:20847424	p(HGNC:SHC4, pmod(Ph, Thr)) association act(a(MESHC:Cytokines))
pmid:22122372	p(HGNC:SHC4) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:19383491	tloc(p(HGNC:SLC2A4), fromLoc(MESHCS:"Intracellular Space"), toLoc(MESHCS:"Cell Membrane")) increases bp(GOBP:"glucose import")
pmid:19383491	tloc(p(HGNC:SLC2A8), fromLoc(MESHCS:"Intracellular Space"), toLoc(MESHCS:"Cell Membrane")) increases bp(GOBP:"glucose import")
pmid:19885299	p(HGNC:SOS2) association bp(GOBP:"insulin receptor signaling pathway")
pmid:19523444	p(HGNC:TTR) decreases p(HGNC:APP, frag("672_713"))
pmid:14976144	p(HGNC:VAMP2) positiveCorrelation a(MESH:D050417)
pmid:14976144	p(HGNC:VAMP2) positiveCorrelation a(GOCC:cell)
pmid:24529526	p(MGI:Gcg) decreases path(MESHD:Inflammation)
pmid:24529526	p(MGI:Gcg) increases bp(GOBP:"cell proliferation")
pmid:24529526	p(MGI:Gcg) decreases bp(GOBP:"apoptotic process")
pmid:24529526	p(MGI:Ins2) decreases path(MESHD:Inflammation)
pmid:24529526	p(MGI:Ins2) increases bp(GOBP:"cell proliferation")
pmid:24529526	p(MGI:Ins2) decreases bp(GOBP:"apoptotic process")
pmid:19383491	p(RGD:Pomc) positiveCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:19519303	p(SFAM:"FOXO Family") decreases bp(GOBP:"cell death")
pmid:19519303	p(SFAM:"FOXO Family") increases bp(MESHPP:Longevity)
pmid:12185156	p(SFAM:"INS Family") association p(HGNC:PPP1R3A)
pmid:12185156	p(SFAM:"INS Family") association p(HGNC:PIK3R1)
pmid:17049785	p(SFAM:"PAK Family", pmod(Ph)) association bp(PTS:"Insulin receptor signaling pathway")
pmid:19519303	path(DO:"post-surgical hypoinsulinemia") association path(MESHD:Hyperinsulinism)
pmid:19885299	path(MESHD:"Cerebrovascular Disorders") positiveCorrelation path(MESHD:"Diabetes Mellitus, Type 2")
pmid:19885299	path(MESHD:"Cerebrovascular Disorders") positiveCorrelation path(MESHD:Obesity)
pmid:26996954	path(MESHD:"Cerebrovascular Disorders") association g(HGNC:SORL1)
pmid:26996954	path(MESHD:"Cerebrovascular Disorders") increases path(MESHD:Dementia)
pmid:26996954	path(MESHD:"Cerebrovascular Disorders") association g(DBSNP:rs3824968)
pmid:19885299	path(MESHD:"Diabetes Mellitus") association path(MESHD:Dementia)
pmid:19885299	path(MESHD:"Diabetes Mellitus") association g(HGNC:APOE)
pmid:21289241	path(MESHD:"Diabetes, Gestational") negativeCorrelation p(HGNC:INSR)
pmid:19519303	path(MESHD:"Glucose Intolerance") negativeCorrelation a(CHEBI:nutrient)
pmid:19519303	path(MESHD:"Glucose Intolerance") positiveCorrelation p(HGNC:APP, frag("672_713"))
pmid:19519303	path(MESHD:"Glucose Intolerance") association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:22142155	path(MESHD:"Insulin Resistance") association path(MESHD:"Alzheimer Disease")
pmid:19885299	path(MESHD:Obesity) increases p(SFAM:"IL1 Family")
pmid:19885299	path(MESHD:Obesity) increases p(HGNC:TNF)
pmid:19885299	path(MESHD:Obesity) positiveCorrelation path(MESHD:"Cerebrovascular Disorders")
pmid:22115781	path(MESHD:Obesity) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:19519303	act(r(HGNC:IDE), ma(tscript)) association bp(GOBP:"insulin receptor signaling pathway")
pmid:19519303	r(HGNC:IGF1) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19519303	r(HGNC:INS) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19519303	r(HGNC:INSR) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:19885299	r(HGNC:MAPT) association act(p(HGNC:IGF1))
pmid:22720189	r(HGNC:MAPT) association m(HGNC:"MIR16-1")
pmid:15261762	a(CHEBI:"(25R)-cholest-5-ene-3beta,26-diol") decreases p(HGNC:SMPD2)
pmid:14970312	a(CHEBI:"acyl-CoA") decreases bp(GOBP:"neuron apoptotic process")
pmid:14970312	a(CHEBI:"alpha-tocopherol") decreases bp(GOBP:"regulation of sphingomyelin catabolic process")
pmid:20061608	a(CHEBI:triglyceride) positiveCorrelation p(HGNC:APP, frag("672_713"))
pmid:22580286	a(GOCC:endolysosome) association a(CHEBI:cholesterol)
pmid:20049331	act(a(GOCC:microtubule)) association a(CHEBI:"amyloid-beta")
pmid:18650430	a(HBP:"YENPTY endocytosis motif (APP)") decreases p(HGNC:APP, frag("672_713"))
pmid:18650430	a(HBP:"YENPTY endocytosis motif (APP)") association p(HGNC:APBB1)
pmid:18650430	a(HBP:"YENPTY endocytosis motif (APP)") association p(HGNC:APBB2)
pmid:18650430	a(HBP:"YENPTY endocytosis motif (APP)") association p(HGNC:APBB3)
pmid:18650430	a(HBP:"YENPTY endocytosis motif (APP)") association p(HGNC:APBA1)
pmid:18650430	a(HBP:"YENPTY endocytosis motif (APP)") association p(HGNC:APBA2)
pmid:18650430	a(HBP:"YENPTY endocytosis motif (APP)") association p(HGNC:APBA3)
pmid:18650430	a(HBP:"YENPTY endocytosis motif (APP)") association p(HGNC:DAB1)
pmid:18650430	a(HBP:"YENPTY endocytosis motif (APP)") association p(HGNC:MAPK8)
pmid:18650430	a(HBP:"YENPTY endocytosis motif (APP)") association p(HGNC:MAPK9)
pmid:18650430	a(HBP:"YENPTY endocytosis motif (APP)") association p(HGNC:MAPK10)
pmid:21244351	a(MESH:D005971) decreases bp(GOBP:"positive regulation of synaptic transmission")
pmid: 21543606	a(MESH:D009836) decreases bp(GOBP:myelination)
pmid:26996954	a(NIFT:"Brain volume") association g(DBSNP:rs3824968)
pmid: 21543606	a(NIFT:"Fractional anisotropy") decreases a(NIFT:"White matter")
pmid: 21543606	a(NIFT:"Fractional anisotropy") association bp(GOBP:"regulation of lipid metabolic process")
pmid:26996954	a(NIFT:"Grey matter atrophy") positiveCorrelation a(CHEBI:"amyloid-beta")
pmid:26996954	a(NIFT:"White Matter Hyperintensity") association g(DBSNP:rs3824968)
pmid:3122646	a(NIFT:"White matter") association p(HGNC:MAPT)
pmid:20427281	bp(GO:"GO:0036315") association p(HGNC:MYLIP)
pmid: 21543606	bp(GOBP:"axonal defasciculation") association bp(GOBP:"regulation of synaptic plasticity")
pmid:20232416	bp(GOBP:"cholesterol homeostasis") association p(HGNC:LDLR)
pmid:21676498	bp(GOBP:"cholesterol homeostasis") association p(HGNC:APOE)
pmid: 22646481	bp(GOBP:"cholesterol homeostasis") association p(HGNC:APP, frag("672_713"))
pmid:22496686	bp(GOBP:"cholesterol import") association p(HGNC:LDLR)
pmid:20049331	bp(GOBP:"cholesterol metabolic process") association p(HGNC:LDLR)
pmid:14970312	bp(GOBP:"cholesterol metabolic process") association path(MESHD:"Alzheimer Disease")
pmid:1632469	bp(GOBP:"cholesterol metabolic process") association p(HGNC:LRP1)
pmid:14970312	bp(GOBP:"cholesterol metabolic process") increases a(CHEBI:cholesterol)
pmid:22496686	bp(GOBP:"embryo development") association p(HGNC:LDLR)
pmid:22496686	bp(GOBP:"neural tube development") association p(HGNC:RELN)
pmid:22496686	bp(GOBP:"neuron migration") association p(HGNC:LDLR)
pmid:22410445	bp(GOBP:"pre-B cell receptor expression") association g(HGNC:SORL1)
pmid: 21543606	bp(GOBP:"regulation of lipid metabolic process") association a(NIFT:"Fractional anisotropy")
pmid: 21543606	bp(GOBP:"regulation of lipid metabolic process") association bp(GOBP:myelination)
pmid:14970312	bp(GOBP:"regulation of lipid metabolic process") association bp(MESHPP:"Oxidative Stress")
pmid:14970312	bp(GOBP:"regulation of lipid metabolic process") association p(HGNC:APP, frag("672_713"))
pmid:1632469	bp(GOBP:"regulation of peptidase activity") association p(HGNC:LRP1)
pmid:14970312	bp(GOBP:"regulation of sphingomyelin catabolic process") decreases a(CHEBI:ceramide)
pmid:14970312	bp(GOBP:"regulation of sphingomyelin catabolic process") decreases a(CHEBI:cholesterol)
pmid:14970312	bp(GOBP:"sphingolipid metabolic process") association path(MESHD:"Alzheimer Disease")
pmid:14970312	bp(GOBP:"sphingolipid metabolic process") increases a(CHEBI:ceramide)
pmid: 21543606	bp(GOBP:myelination) association bp(GOBP:"regulation of lipid metabolic process")
pmid: 21543606	bp(GOBP:myelination) association bp(GOBP:"regulation of synaptic plasticity")
pmid:22673115	act(complex(GOCC:"retromer complex"), ma(tport)) directlyIncreases tloc(p(HGNC:SORL1), fromLoc(MESHCS:Endosomes), toLoc(MESHCS:"trans-Golgi Network"))
pmid:21873229	complex(a(CHEBI:lipid), p(HGNC:APOE), p(HGNC:HSPG2)) increases complex(p(HGNC:APOE), p(HGNC:LDLR))
pmid:22038977	complex(p(HGNC:AGRN), p(HGNC:LRP4)) directlyIncreases p(HGNC:MUSK, pmod(Ph))
pmid:18650430	complex(p(HGNC:APBA1), p(HGNC:ARL3)) increases tloc(p(HGNC:APP))
pmid:18650430	complex(p(HGNC:APBA2), p(HGNC:ARL3)) increases tloc(p(HGNC:APP))
pmid:18650430	complex(p(HGNC:APBA3), p(HGNC:ARL3)) increases tloc(p(HGNC:APP))
pmid:18650430	complex(p(HGNC:APBB1), p(HGNC:APP), p(HGNC:LRP2)) increases tloc(p(HGNC:APP))
pmid:22383525	complex(p(HGNC:APP, frag("672_713")), p(HGNC:LDLR)) increases deg(p(HGNC:APP, frag("672_713")))
pmid:18675468	act(complex(p(HGNC:LRP8), p(HGNC:RELN))) directlyIncreases act(p(SFAM:"SRC Family"))
pmid:19515914	complex(p(HGNC:LRP8), p(HGNC:RELN)) association bp(GOBP:"regulation of neuron migration")
pmid:19515914	complex(p(HGNC:RELN), p(HGNC:VLDLR)) association bp(GOBP:"regulation of neuron migration")
pmid:18650430	composite(p(HGNC:GGA1), p(HGNC:PACS1), p(HGNC:SORL1)) decreases p(HGNC:APP, frag("672_713"))
pmid:18650430	composite(p(HGNC:GGA2), p(HGNC:PACS1), p(HGNC:SORL1)) decreases p(HGNC:APP, frag("672_713"))
pmid:18650430	composite(p(HGNC:GGA3), p(HGNC:PACS1), p(HGNC:SORL1)) decreases p(HGNC:APP, frag("672_713"))
pmid:22496686	composite(p(HGNC:LRP1), p(HGNC:LRP10), p(HGNC:LRP11), p(HGNC:LRP2), p(HGNC:LRP3), p(HGNC:LRP4), p(HGNC:LRP5), p(HGNC:LRP6), p(HGNC:LRP8)) association p(HGNC:APOE)
pmid:22496686	composite(p(HGNC:LRP1), p(HGNC:LRP10), p(HGNC:LRP11), p(HGNC:LRP2), p(HGNC:LRP3), p(HGNC:LRP4), p(HGNC:LRP5), p(HGNC:LRP6), p(HGNC:LRP8)) increases act(p(SFAM:"MAPK Erk1/2 Family"))
pmid:22496686	composite(p(HGNC:LRP1), p(HGNC:LRP10), p(HGNC:LRP11), p(HGNC:LRP2), p(HGNC:LRP3), p(HGNC:LRP4), p(HGNC:LRP5), p(HGNC:LRP6), p(HGNC:LRP8)) decreases act(p(SFAM:"MAPK JNK Family"))
pmid:22496686	composite(p(HGNC:PSEN1), p(HGNC:PSEN2)) regulates deg(p(HGNC:LRP1))
pmid:22496686	composite(p(HGNC:PSEN1), p(HGNC:PSEN2)) association p(SFAM:"NOTCH Family", frag("?"))
pmid:22496686	composite(p(HGNC:PSEN1), p(HGNC:PSEN2)) association p(HGNC:ERBB4, frag("?"))
pmid:22496686	composite(p(HGNC:PSEN1), p(HGNC:PSEN2)) association p(HGNC:FUNDC2, frag("?"))
pmid:22496686	composite(p(HGNC:PSEN1), p(HGNC:PSEN2)) association p(SFAM:"NOTCH Family")
pmid:20089128	composite(p(HGNC:PSEN1), p(HGNC:PSEN2)) association p(SFAM:"NOTCH Family")
pmid:22496686	composite(p(HGNC:PSEN1), p(HGNC:PSEN2)) association bp(GOBP:"apoptotic process")
pmid:21709374	g(DBSNP:rs1050283) association g(HGNC:OLR1)
pmid:21709374	g(DBSNP:rs1050283) association path(MESHD:"Alzheimer Disease")
pmid:18191876	g(DBSNP:rs1050283) association path(MESHD:"Alzheimer Disease")
pmid: 21543606	g(DBSNP:rs11136000) association path(MESHD:"Alzheimer Disease")
pmid: 21543606	g(DBSNP:rs11136000) association p(HGNC:CLU)
pmid:24162737	g(DBSNP:rs11218343) association g(HGNC:SORL1)
pmid:23565137	g(DBSNP:rs11218343) association g(HGNC:SORL1)
pmid:18191876	g(DBSNP:rs12316150) association path(MESHD:"Alzheimer Disease")
pmid:22410445	g(DBSNP:rs1699102) decreases bp(GOBP:"pre-B cell receptor expression")
pmid:22410445	g(DBSNP:rs2070045) decreases bp(GOBP:"pre-B cell receptor expression")
pmid:26996954	g(DBSNP:rs3824968) association p(HGNC:SORL1)
pmid:26996954	g(DBSNP:rs3824968) association g(HGNC:SORL1)
pmid:26996954	g(DBSNP:rs3824968) association g(HGNC:SORL1)
pmid:26996954	g(DBSNP:rs3824968) negativeCorrelation a(NIFT:"Grey matter volume")
pmid:26996954	g(DBSNP:rs3824968) association path(MESHD:"Amyloid Neuropathies")
pmid:26996954	g(DBSNP:rs3824968) association a(NIFT:"Brain volume")
pmid:26996954	g(DBSNP:rs3824968) association a(NIFT:"White Matter Hyperintensity")
pmid:26996954	g(DBSNP:rs3824968) increases act(a(CHEBI:"amyloid-beta"))
pmid:26996954	g(DBSNP:rs3824968) association path(MESHD:"Cerebrovascular Disorders")
pmid:18191876	g(DBSNP:rs669) association path(MESHD:"Alzheimer Disease")
pmid:18191876	g(HGNC:A2M) causesNoChange path(MESHD:"Alzheimer Disease")
pmid:27176073	g(HGNC:LRP2, var("?")) increases bp(GOBP:cognition)
pmid:20427281	g(HGNC:LRP8) increases bp(GOBP:"central nervous system development")
pmid:20427281	g(HGNC:LRP8) increases bp(GOBP:"lipid metabolic process")
pmid:21709374	g(HGNC:OLR1) association g(DBSNP:rs1050283)
pmid:21709374	g(HGNC:OLR1) increases r(HGNC:OLR1)
pmid:22410445	g(HGNC:SORL1) association bp(GOBP:"pre-B cell receptor expression")
pmid:17975299	g(HGNC:SORL1) association path(MESHD:"Alzheimer Disease")
pmid:24162737	g(HGNC:SORL1) association g(DBSNP:rs11218343)
pmid:23565137	g(HGNC:SORL1) association g(DBSNP:rs11218343)
pmid:21280075	act(g(HGNC:SORL1), ma(tport)) increases tloc(p(HGNC:APP))
pmid:26996954	g(HGNC:SORL1) association g(DBSNP:rs3824968)
pmid:26996954	g(HGNC:SORL1) association g(DBSNP:rs3824968)
pmid:26996954	g(HGNC:SORL1) association path(MESHD:"Cerebrovascular Disorders")
pmid:20007471	g(HGNC:SORL1) increases bp(GOBP:"ERK1 and ERK2 cascade")
pmid:20007471	g(HGNC:SORL1) increases bp(GOBP:"ERK5 cascade")
pmid:20007471	g(HGNC:SORL1) decreases p(HGNC:APP, frag("672_713"))
pmid:20427281	g(HGNC:VLDLR) increases bp(GOBP:"central nervous system development")
pmid:20427281	g(HGNC:VLDLR) increases bp(GOBP:"lipid metabolic process")
pmid:19665999	m(HGNC:MIR205) decreases r(HGNC:LRP1)
pmid:19665999	m(HGNC:MIR205) association r(HGNC:LRP1)
pmid:21709374	m(HGNC:MIR369) association r(HGNC:OLR1)
pmid:19515914	p(FPLX:Integrins) association bp(GOBP:"neuron projection development")
pmid:19515914	p(FPLX:Integrins) association bp(GOBP:"regulation of neuron migration")
pmid:18650430	p(HGNC:APBB3) association a(HBP:"YENPTY endocytosis motif (APP)")
pmid:22496686	p(HGNC:HDLBP) association p(HGNC:APOE)
pmid:12117549	p(HGNC:LRP1B) increases complex(p(HGNC:APOE), p(HGNC:APP, frag("672_713")))
pmid:20427281	p(HGNC:LRP8, pmod(Ub)) increases deg(p(HGNC:LRP8))
pmid:22038977	p(HGNC:MUSK, pmod(Ph)) increases bp(GOBP:"transmission of nerve impulse")
pmid:20427281	p(HGNC:MYLIP) increases deg(p(HGNC:LDLR))
pmid:20427281	p(HGNC:MYLIP) association bp(GO:"GO:0036315")
pmid:20427281	p(HGNC:MYLIP) increases p(HGNC:VLDLR, pmod(Ub))
pmid:20427281	p(HGNC:MYLIP) increases p(HGNC:LRP8, pmod(Ub))
pmid:20427281	p(HGNC:NR1H2) regulates p(HGNC:MYLIP)
pmid:20427281	act(p(HGNC:NR1H2)) decreases complex(p(HGNC:RELN), p(HGNC:VLDLR))
pmid:20427281	act(p(HGNC:NR1H2)) decreases p(HGNC:DAB1, pmod(Ph))
pmid:20427281	p(HGNC:NR1H3) regulates p(HGNC:MYLIP)
pmid:20427281	act(p(HGNC:NR1H3)) decreases complex(p(HGNC:RELN), p(HGNC:VLDLR))
pmid:20427281	act(p(HGNC:NR1H3)) decreases p(HGNC:DAB1, pmod(Ph))
pmid:18191876	p(HGNC:OLR1) association path(MESHD:"Alzheimer Disease")
pmid:18191876	p(HGNC:OLR1) association path(MESHD:"Alzheimer Disease")
pmid:20518072	p(HGNC:SMPD2) increases a(CHEBI:ceramide)
pmid:23279143	p(HGNC:SORCS1) association path(MESHD:"Alzheimer Disease")
pmid:23279143	p(HGNC:SORCS1) association path(MESHD:"Diabetes Mellitus, Type 2")
pmid:21280075	p(HGNC:SORCS1) directlyDecreases act(complex(SCOMP:"gamma Secretase Complex"), ma(pep))
pmid:21280075	p(HGNC:SORCS1) directlyDecreases p(HGNC:APP, frag("672_713"))
pmid:25570489	p(HGNC:SORCS1) association a(NIFT:"Ventricular expansion")
pmid:20232416	p(HGNC:SRSF10) regulates p(HGNC:LDLR)
pmid:20427281	p(HGNC:VLDLR, pmod(Ub)) increases deg(g(HGNC:VLDLR))
pmid:18675468	act(p(SFAM:"SRC Family")) directlyIncreases act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits"))
pmid:22496686	p(SFAM:"p160/SRC Family") increases act(p(HGNC:LRP8))
pmid:21676498	r(HGNC:APOE) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:21676498	r(HGNC:APOE) positiveCorrelation r(HGNC:LRP1)
pmid:21676498	r(HGNC:APOE) increases p(HGNC:APOE)
pmid:21709374	r(HGNC:OLR1) association m(HGNC:MIR369)
pmid:21709374	r(HGNC:OLR1) increases p(HGNC:OLR1)
pmid:23279143	r(HGNC:SORCS1) decreases p(HGNC:APP, frag("672_713"))
pmid:22118466	bp(GOBP:"plasma membrane fusion") increases bp(GOBP:"clathrin-dependent endocytosis")
pmid:22710270	g(DBSNP:rs3757536) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22710270	g(DBSNP:rs3757536) association g(HGNC:CADPS2)
pmid:22118466	g(GFAM:SNAREs) increases bp(GOBP:"plasma membrane fusion")
pmid:22118466	g(GFAM:SNAREs) increases bp(GOBP:"clathrin-dependent endocytosis")
pmid:22710270	g(HGNC:CADPS2) association path(MESHD:"Alzheimer Disease")
pmid:22710270	g(HGNC:CADPS2) association g(DBSNP:rs3757536)
pmid:22512552	a(CHEBI:"1H-pyrazole") decreases p(HGNC:NOS1)
pmid:24587007	a(CHEBI:ethanol) decreases p(MGI:Ifna13)
pmid:24587007	a(CHEBI:ethanol) decreases act(p(GFAM:"Glutamate ionotropic receptor NMDA type subunits"))
pmid:24587007	a(CHEBI:ethanol) decreases p(MGI:Ifng)
pmid:24587007	a(CHEBI:ethanol) decreases a(CHEBI:lipopolysaccharide)
pmid:22512552	a(CHEBI:kynurenamines) decreases p(HGNC:NOS1)
pmid:24293250	a(CHEBI:nanoparticle) association p(HGNC:NOS1)
pmid:24923557	a(CHEBI:sirolimus) decreases a(CHEBI:"nitric oxide")
pmid:12218642	a(CHEBI:statin) increases p(HGNC:NOS3)
pmid:24090820	a(MESHC:"alpha-iso-cubebene") decreases p(HGNC:NOS2)
pmid:22431227	act(a(MESHC:Acetylcholinesterase)) association p(HGNC:NOS3)
pmid:9782132	bp(GOBP:"viral process") increases p(HGNC:NOS2)
pmid:22512552	bp(MESHPP:"Synaptic Transmission") association a(CHEBI:"nitric oxide")
pmid:16054114	complex(GOCC:"high-density lipoprotein particle") decreases a(CHEBI:"nitric oxide")
pmid:16054114	complex(GOCC:"high-density lipoprotein particle") decreases a(ADO:peroxynitrite)
pmid:16054114	complex(GOCC:"low-density lipoprotein particle") decreases a(CHEBI:"nitric oxide")
pmid:16054114	complex(GOCC:"low-density lipoprotein particle") decreases a(ADO:peroxynitrite)
pmid:20670888	complex(a(CHEBI:"nitric oxide"), p(HGNC:XIAP)) decreases bp(GOBP:"regulation of ubiquitin protein ligase activity")
pmid:20670888	complex(a(CHEBI:"nitric oxide"), p(HGNC:XIAP)) increases bp(GOBP:"apoptotic signaling pathway")
pmid:22237943	complex(a(CHEBI:fucoidan), p(HGNC:APP)) increases bp(GOBP:"positive regulation of JNK cascade")
pmid:21443265	complex(p(HGNC:APOE), p(HGNC:NOS1)) increases bp(GOBP:"peptidyl-cysteine S-nitrosylation")
pmid:22874667	complex(p(HGNC:CDK5), p(HGNC:NOS1)) increases bp(GOBP:"peptidyl-cysteine S-trans-nitrosylation")
pmid:11556547	g(HGNC:ASS1) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:11556547	g(HGNC:ASS1) association bp(GOBP:"microglial cell activation")
pmid:11556547	g(HGNC:ASS1) positiveCorrelation g(HGNC:NOS2)
pmid:11556547	g(HGNC:GFAP) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:11556547	g(HGNC:NOS2) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:11556547	g(HGNC:NOS2) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:11556547	g(HGNC:NOS2) association bp(GOBP:"microglial cell activation")
pmid:11556547	g(HGNC:NOS2) positiveCorrelation g(HGNC:ASS1)
pmid:19885299	g(HGNC:NOS3) association path(MESHD:"Alzheimer Disease")
pmid:19885299	g(HGNC:NOS3) association bp(MESHPP:"Polymorphism, Single Nucleotide")
pmid:11556547	act(p(HGNC:ASS1), ma(cat)) increases rxn(reactants(a(CHEBI:"L-citrulline")), products(a(CHEBI:"L-arginine")))
pmid:11556547	p(HGNC:ASS1) increases a(CHEBI:"nitric oxide")
pmid:16813604	p(HGNC:NOS3, var("p.Glu298Asp")) association path(MESHD:"Alzheimer Disease")
pmid:16813604	p(HGNC:NOS3, var("p.Glu298Asp")) association path(MESHD:"Alzheimer Disease")
pmid:19419557	p(MESH:D058468) increases a(CHEBI:"nitric oxide")
pmid:19419557	p(MESH:D058468) increases bp(GOBP:"regulation of calcium-mediated signaling")
pmid:24587007	p(MGI:Ifna13) increases a(CHEBI:"nitric oxide")
pmid:24621589	p(MGI:Ifna13) increases a(CHEBI:"nitric oxide")
pmid:24586690	p(MGI:Runx1) regulates a(CHEBI:"nitric oxide")
pmid:24586690	p(MGI:Runx1) regulates a(MESH:D017628)
pmid:24586690	p(MGI:Runx1) association bp(GOBP:"regulation of histone deacetylase activity")
pmid:24586690	p(MGI:Runx1) regulates bp(MESHPP:"Cell Proliferation")
pmid:8879214	p(MGI:Tgfb1) negativeCorrelation p(MGI:Nos2)
pmid:19419557	act(p(SFAM:"GRIA Family")) increases a(CHEBI:"nitric oxide")
pmid:19419557	act(p(SFAM:"GRIA Family")) increases bp(GOBP:"negative regulation of calcium-mediated signaling")
pmid:24905226	a(CHEBI:"astragaloside IV") decreases act(p(HGNC:APP, frag("672_713")))
pmid:24905226	a(CHEBI:"astragaloside IV") decreases bp(GOBP:"positive regulation of mitochondrial membrane permeability involved in apoptotic process")
pmid:21253550	a(CHEBI:"ethylene glycol bis(2-aminoethyl)tetraacetic acid") decreases act(complex(SCOMP:"gamma Secretase Complex"), ma(pep))
pmid:21253550	a(CHEBI:"ethylenediaminetetraacetic acid") decreases act(complex(SCOMP:"gamma Secretase Complex"), ma(pep))
pmid:24293250	a(CHEBI:"gold nanoparticle") decreases bp(GOBP:"amyloid fibril formation")
pmid:21800078	a(CHEBI:"linoleic acid") directlyDecreases p(HGNC:BACE1)
pmid:24293250	a(CHEBI:"silver nanoparticle") decreases bp(GOBP:"amyloid fibril formation")
pmid:27176073	a(CHEBI:"vitamin D") decreases p(HGNC:APP, frag("672_713"))
pmid:21718295	a(CHEBI:caffeine) decreases p(HGNC:APP, frag("672_713"))
pmid:17291491	a(CHEBI:carbazole) decreases a(HBP:"amyloid-beta fibrils")
pmid:17291491	a(CHEBI:carbazole) decreases a(CHEBI:"amyloid-beta")
pmid:21718295	a(CHEBI:hyperforin) decreases p(HGNC:APP, frag("672_713"))
pmid:24879954	a(CHEBI:montelukast) decreases act(p(HGNC:APP, frag("672_713")))
pmid:24879954	a(CHEBI:montelukast) decreases act(p(HGNC:APP, frag("672_713")))
pmid:24879954	a(CHEBI:montelukast) decreases p(MGI:Cysltr1)
pmid:17368447	a(CHEBI:paroxetine) increases bp(GOBP:cognition)
pmid:17368447	a(CHEBI:paroxetine) decreases a(CHEBI:"amyloid-beta")
pmid:15314261	a(CHEBI:paroxetine) decreases p(HGNC:APP)
pmid:15314261	a(CHEBI:paroxetine) decreases tloc(p(HGNC:APP, frag("672_713")), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:21718295	a(CHEBI:pentetrazol) decreases p(HGNC:APP, frag("672_713"))
pmid:21253550	a(CHEBI:phenanthroline) decreases act(complex(SCOMP:"gamma Secretase Complex"), ma(pep))
pmid:24769037	a(CHEBI:pioglitazone) decreases p(HGNC:FASLG)
pmid:24769037	a(CHEBI:pioglitazone) decreases p(HGNC:APP, frag("672_713"))
pmid:24838579	a(CHEBI:pioglitazone) decreases path(MESHD:"Plaque, Amyloid")
pmid:15639314	a(CHEBI:probucol) directlyDecreases a(CHEBI:cholesterol)
pmid:15639314	a(CHEBI:probucol) increases p(HGNC:APOE)
pmid:15639314	a(CHEBI:probucol) decreases p(HGNC:APP, frag("672_713"))
pmid:15639314	a(CHEBI:probucol) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:23785163	a(CHEBI:pyrazole) decreases p(HGNC:APP, frag("672_713"))
pmid:18079026	a(CHEBI:quetiapine) decreases p(HGNC:APP, frag("672_770"))
pmid:21718295	a(CHEBI:rifampicin) decreases p(HGNC:APP, frag("672_713"))
pmid:21881209	a(CHEBI:thiethylperazine) increases act(p(MGI:Abcc1))
pmid:21881209	a(CHEBI:thiethylperazine) decreases path(MESHD:Nausea)
pmid:21881209	a(CHEBI:thiethylperazine) decreases path(MESHD:Vomiting)
pmid:21718295	a(CHEBI:verapamil) decreases p(HGNC:APP, frag("672_713"))
pmid:24918635	a(HBP:"amyloid-beta oligomers") positiveCorrelation p(HGNC:MMP9)
pmid:21214928	a(MESHC:"alpha-sAPP protein, human") equivalentTo a(HBP:"sAPP-alpha")
pmid:24279603	a(MESHC:meserine) decreases p(HGNC:APP, frag("672_713"))
pmid:24279603	a(MESHC:meserine) decreases p(HGNC:APP)
pmid:18429932	bp(GOBP:"cholesterol efflux") decreases p(HGNC:APP, frag("672_713"))
pmid:20847424	bp(GOBP:"cholesterol transport") association p(HGNC:APOE)
pmid:20847424	bp(GOBP:"cholesterol transport") association p(HGNC:APP, frag("672_713"))
pmid:19885299	bp(GOBP:"hydrogen peroxide-mediated programmed cell death") positiveCorrelation tloc(a(CHEBI:"amyloid-beta"), fromLoc(GOCC:intracellular), toLoc(GOCC:"extracellular space"))
pmid:22718756	bp(GOBP:"neurofibrillary tangle assembly") positiveCorrelation complex(GOCC:"neurofibrillary tangle")
pmid:20570967	bp(GOBP:autophagy) decreases p(HGNC:SOD1, var("?"))
pmid:24126163	bp(GOBP:growth) association p(HGNC:PLAT)
pmid:21800078	complex(a(CHEBI:"linoleic acid"), p(HGNC:PPARG)) directlyDecreases p(HGNC:APP, frag("672_713"))
pmid:20205643	complex(g(HGNC:CCL2), g(HGNC:CCR2)) regulates bp(GOBP:"microglial cell activation involved in immune response")
pmid:20205643	complex(g(HGNC:CCL2), g(HGNC:CCR2)) decreases p(HGNC:APP, frag("672_713"))
pmid:22122372	complex(p(HGNC:APBA1), p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")) association tloc(p(HGNC:APP))
pmid:22122372	complex(p(HGNC:APBA1), p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")) decreases p(HGNC:APP, frag("672_713"))
pmid:10777610	complex(p(HGNC:APBA2), p(HGNC:NFKB1)) decreases p(HGNC:APP, frag("672_713"))
pmid:22782894	complex(p(HGNC:APP), p(HGNC:DCC)) increases bp(GOBP:"axon guidance")
pmid:22782894	complex(p(HGNC:APP), p(HGNC:DCC), p(HGNC:NTN1)) increases act(p(SFAM:"MAPK Erk1/2 Family"))
pmid:22782894	complex(p(HGNC:APP), p(HGNC:NTN1)) decreases p(HGNC:APP, frag("672_713"))
pmid:16452662	complex(p(HGNC:APP), p(HGNC:RTN4R)) decreases act(p(HGNC:APP, frag("672_713")))
pmid:16452662	p(HGNC:RTN4R) increases complex(p(HGNC:APP), p(HGNC:RTN4R))
pmid:16452662	p(HGNC:RTN4R) association p(HGNC:APP)
pmid:17077814	complex(p(HGNC:APP, frag("672_713")), p(HGNC:CLU)) decreases a(CHEBI:"amyloid-beta")
pmid:21696420	complex(p(HGNC:BAG3), p(HGNC:HSPB8)) increases bp(GOBP:autophagy)
pmid:21696420	complex(p(HGNC:BAG3), p(HGNC:HSPB8)) decreases a(HBP:"amyloid-beta aggregates")
pmid:20570967	complex(p(HGNC:BAG3, var("?")), p(HGNC:HSPB8)) decreases p(HGNC:APP, frag("672_713"))
pmid:20205643	complex(p(HGNC:CCL2), p(HGNC:CCR2)) negativeCorrelation a(CHEBI:"amyloid-beta")
pmid:22434822	complex(p(HGNC:CLSTN1), p(HGNC:KLC1)) increases act(p(HGNC:APP), ma(tport))
pmid:22434822	deg(complex(p(HGNC:CLSTN1), p(HGNC:KLC1))) decreases a(CHEBI:"amyloid-beta")
pmid:15270203	complex(p(HGNC:GCG), p(HGNC:GLP1R)) decreases p(HGNC:APP, frag("672_713"))
pmid:20570967	complex(p(HGNC:HSPB8), p(HGNC:SOD1, var("?"))) increases bp(GOBP:autophagy)
pmid:19237574	composite(a(CHEBI:metformin), p(HGNC:INS)) decreases p(HGNC:APP, frag("672_713"))
pmid:23022416	composite(g(DBSNP:rs3818361), g(DBSNP:rs429358)) association path(MESHD:"Alzheimer Disease")
pmid:23022416	g(DBSNP:rs3818361) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:123	g(HGNC:APP, var("c.673A>T")) decreases path(MESHD:"Alzheimer Disease")
pmid:20007471	g(HGNC:BDNF) increases g(HGNC:SORL1)
pmid:20007471	g(HGNC:BDNF) decreases p(HGNC:APP, frag("672_713"))
pmid:23164821	deg(g(HGNC:EGR1)) decreases p(HGNC:APP, frag("672_713"))
pmid:22122372	g(HGNC:EZH2P1) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:23164821	deg(g(HGNC:KLF1)) decreases act(p(HGNC:APP, frag("672_713")))
pmid:22122372	g(HGNC:MLLT10P1) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22122372	g(HGNC:MLLT10P2) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:23164821	deg(g(HGNC:NAB2)) decreases act(p(HGNC:APP, frag("672_713")))
pmid:17182778	g(HGNC:RTN4) decreases p(HGNC:APP, frag("672_713"))
pmid:21994399	m(HGNC:MIR137) negativeCorrelation r(HGNC:SPTLC3)
pmid:21994399	m(HGNC:MIR137) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:21994399	m(HGNC:MIR29A) negativeCorrelation r(HGNC:SPTLC3)
pmid:21994399	m(HGNC:MIR29A) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:16207708	p(HGNC:ABCA1) decreases p(HGNC:APP, frag("672_713"))
pmid:18429932	p(HGNC:ABCA7) increases bp(GOBP:"cholesterol efflux")
pmid:18429932	p(HGNC:ABCA7) decreases p(HGNC:APP, frag("672_713"))
pmid:23789959	p(HGNC:ABCC1) association bp(GO:"GO:0097242")
pmid:23181169	p(HGNC:ABCG2) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:23181169	p(HGNC:ABCG2) decreases act(complex(SCOMP:"Nfkb Complex"))
pmid:23789959	p(HGNC:ABCG2) association bp(GO:"GO:0097242")
pmid:17112471	p(HGNC:ADAM19) increases a(HBP:"sAPP-alpha")
pmid:17112471	p(HGNC:ADAM19) increases a(HBP:"sAPP-alpha")
pmid:17112471	p(HGNC:ADAM19) association path(MESHD:"Alzheimer Disease")
pmid:22122372	p(HGNC:AFDN) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:10428074	p(HGNC:APOE, var("p.Cys130Arg")) increases p(HGNC:APP, frag("672_713"))
pmid:20847424	act(p(HGNC:CHRM1)) increases act(p(HGNC:APP), ma(pep))
pmid:24634659	p(HGNC:CNR1) decreases act(p(CHEBI:"amyloid-beta"))
pmid:24634659	p(HGNC:CNR2) decreases act(p(CHEBI:"amyloid-beta"))
pmid:20624932	p(HGNC:CPQ) increases deg(p(HGNC:APP, frag("672_713")))
pmid:20624932	p(HGNC:CPQ) decreases p(HGNC:APP, frag("672_713"))
pmid:18957217	p(HGNC:CST3) decreases p(HGNC:CASP8)
pmid:18957217	p(HGNC:CST3) decreases p(HGNC:CTSB)
pmid:18957217	p(HGNC:CST3) decreases p(HGNC:APP, frag("672_713"))
pmid:22122372	p(HGNC:EZH1) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22122372	p(HGNC:EZH2) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:15639314	act(p(HGNC:HMGCR)) increases a(CHEBI:cholesterol)
pmid:18021299	p(HGNC:IL1RN) decreases complex(p(HGNC:IL1B), p(HGNC:IL1R1))
pmid:18021299	p(HGNC:IL1RN) decreases act(p(HGNC:IL1B))
pmid:22122372	p(HGNC:KLC2) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22122372	p(HGNC:KLC3) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22122372	p(HGNC:KLC4) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22122372	p(HGNC:KMT2A) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22122372	p(HGNC:KMT5B) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:18650430	p(HGNC:MAPK9) association a(HBP:"YENPTY endocytosis motif (APP)")
pmid:15658002	act(p(HGNC:MAPK9)) positiveCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:15658002	act(p(HGNC:MAPK9), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:15658002	act(p(HGNC:MAPK9)) positiveCorrelation path(MESHD:Tauopathies)
pmid:15658002	act(p(HGNC:MAPK9), ma(kin)) increases p(HGNC:JUN, pmod(Ph))
pmid:15658002	act(p(HGNC:MAPK9), ma(kin)) increases p(HGNC:ATF2, pmod(Ph))
pmid:16772869	act(p(HGNC:MAPK9), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 422))
pmid:22122372	p(HGNC:MLLT1) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22122372	p(HGNC:MLLT10) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22122372	p(HGNC:MLLT11) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22122372	p(HGNC:MLLT3) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22122372	p(HGNC:MLLT6) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:10672313	p(HGNC:MMP3) association deg(p(HGNC:APP, frag("672_713")))
pmid:12372252	p(HGNC:MMP7) decreases act(p(HGNC:APP, frag("672_713")))
pmid:18813209	p(HGNC:MTRNR2L2) decreases act(p(HGNC:APP, frag("672_713")))
pmid:20224908	p(HGNC:PADI2) association deg(p(HGNC:APP, frag("672_713")))
pmid:14766758	p(HGNC:PDGFRL) increases deg(p(HGNC:APP))
pmid:24126163	p(HGNC:PLAT) association bp(GOBP:growth)
pmid:24126163	p(HGNC:PLAT) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:24126163	p(HGNC:PLAT) increases deg(p(HGNC:APP, frag("672_713")))
pmid:14501010	p(HGNC:PLAT) increases deg(p(HGNC:APP, frag("672_713")))
pmid:10471309	p(HGNC:PLAT) increases p(HGNC:PLG)
pmid:10471309	p(HGNC:PLAT) increases deg(p(HGNC:APP, frag("672_711")))
pmid:17182778	p(HGNC:RTN4) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:22122372	p(HGNC:SUV39H1) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22122372	p(HGNC:SUV39H2) association p(INTERPRO:"Amyloidogenic glycoprotein, intracellular domain, conserved site")
pmid:22382662	p(HGNC:SYVN1) increases bp(GOBP:"regulation of ER-associated ubiquitin-dependent protein catabolic process")
pmid:22382662	p(HGNC:SYVN1) increases p(HGNC:APP, pmod(Ub))
pmid:22382662	p(HGNC:SYVN1) increases p(HGNC:APP, pmod(Ub))
pmid:22382662	p(HGNC:SYVN1) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:22382662	p(HGNC:SYVN1) negativeCorrelation p(HGNC:APP, frag("672_713"))
pmid:21881209	p(MGI:Abcc1) negativeCorrelation a(CHEBI:"amyloid-beta")
pmid:21881209	p(MGI:Abcc1) decreases p(HGNC:APP, frag("672_713"))
pmid:21969301	path(MESH:D058225) negativeCorrelation p(HGNC:EGR1)
pmid:21969301	path(MESHD:Glaucoma) association p(HGNC:EGR1)
pmid:21994399	r(HGNC:SPTLC3) negativeCorrelation m(HGNC:MIR137)
pmid:21994399	r(HGNC:SPTLC3) negativeCorrelation m(HGNC:MIR181C)
pmid:21994399	r(HGNC:SPTLC3) negativeCorrelation m(HGNC:"MIR9-1")
pmid:21994399	r(HGNC:SPTLC3) negativeCorrelation m(HGNC:MIR29A)
pmid:21872584	a(CHEBI:liquiritigenin) decreases p(HGNC:NOTCH2)
pmid:20117143	a(CHEBI:liquiritigenin) decreases p(HGNC:NOTCH2)
pmid:20117143	a(CHEBI:liquiritigenin) decreases path(MESHD:"Alzheimer Disease")
pmid:20117143	a(CHEBI:liquiritigenin) increases a(MESH:D009474)
pmid:19789989	a(CHEBI:liquiritin) increases p(HGNC:NOTCH2)
pmid:19789989	a(CHEBI:liquiritin) increases bp(GOBP:"neuron projection development")
pmid:12471034	bp(GO:"GO:0051604") association complex(p(HGNC:APH1A), p(HGNC:PSEN1))
pmid:12471034	bp(GO:"GO:0051604") association complex(p(HGNC:APH1A), p(HGNC:PSEN2))
pmid:12471034	bp(GO:"GO:0051604") association complex(p(HGNC:APH1A), p(HGNC:NCSTN))
pmid:22496686	bp(GOBP:"cell differentiation") association bp(GOBP:"Notch signaling pathway")
pmid:22496686	bp(GOBP:"regulation of cell fate commitment") association bp(GOBP:"Notch signaling pathway")
pmid:12471034	complex(p(HGNC:APH1A), p(HGNC:NCSTN)) association bp(GO:"GO:0051604")
pmid:12471034	complex(p(HGNC:APH1A), p(HGNC:PSEN1)) association bp(GO:"GO:0051604")
pmid:12471034	complex(p(HGNC:APH1A), p(HGNC:PSEN2)) association bp(GO:"GO:0051604")
pmid:12471034	complex(p(HGNC:NOTCH1), p(HGNC:PSEN1)) association p(HGNC:APH1A)
pmid:20883690	act(p(FPLX:Notch)) increases act(a(HBP:"sAPP-alpha"))
pmid:20883690	act(p(FPLX:Notch)) increases bp(GOBP:"glial cell differentiation")
pmid:20883690	act(p(FPLX:Notch)) increases act(p(HGNC:IL6))
pmid:22496686	p(HGNC:ERBB4, frag("?")) association composite(p(HGNC:PSEN1), p(HGNC:PSEN2))
pmid:22496686	p(HGNC:FUNDC2, frag("?")) association composite(p(HGNC:PSEN1), p(HGNC:PSEN2))
pmid:12802175	p(HGNC:NOTCH2) association path(MESHD:"Alzheimer Disease")
pmid:21872584	p(HGNC:NOTCH2) association path(MESHD:"Alzheimer Disease")
pmid:20117143	p(HGNC:NOTCH2) association path(MESHD:"Alzheimer Disease")
pmid:19789989	p(HGNC:NOTCH2) association path(MESHD:"Alzheimer Disease")
pmid:16515557	p(HGNC:NOTCH2) association path(MESHD:"Neurodegenerative Diseases")
pmid:22461631	p(HGNC:PSEN1, var("p.His163Arg")) decreases act(complex(SCOMP:"gamma Secretase Complex"))
pmid:22461631	p(HGNC:PSEN1, var("p.Met146Leu")) decreases act(complex(SCOMP:"gamma Secretase Complex"))
pmid:20655472	p(HGNC:SIRT1) increases act(p(HGNC:RARB))
pmid:20883690	p(HGNC:STAT3, pmod(Ph)) increases bp(GOBP:"glial cell differentiation")
pmid:20883690	p(HGNC:STAT3, pmod(Ph)) increases act(p(FPLX:Notch))
pmid:10967351	p(SFAM:"DVL Family") association bp(GOBP:"Wnt signaling pathway")
pmid:22496686	p(SFAM:"NOTCH Family", frag("?")) association composite(p(HGNC:PSEN1), p(HGNC:PSEN2))
pmid:17404688	r(HGNC:MYCN) association a(CHEBI:estradiol)
pmid:23373633	r(HGNC:NOL3) association a(CHEBI:estradiol)
pmid:20938992	r(MGI:Mycn) association a(CHEBI:choline)
pmid:20847424	a(CHEBI:"2,4-dinitrophenol") decreases bp(MESHPP:"Oxidative Stress")
pmid:17426120	a(CHEBI:"8-oxoguanine") positiveCorrelation bp(MESHPP:"DNA Damage")
pmid:24619568	a(CHEBI:"acetylsalicylic acid") association a(CHEBI:"reactive oxygen species")
pmid:17015226	bp(GOBP:"glutamate homeostasis") association p(HGNC:SLC1A2)
pmid:20847424	bp(GOBP:"positive regulation of mitochondrial membrane potential") increases a(CHEBI:ATP)
pmid:17426120	bp(MESHPP:"DNA Damage") positiveCorrelation a(CHEBI:"8-oxoguanine")
PubMed Central:PMC3287608	complex(p(HGNC:APP), p(HGNC:SLC25A21)) regulates bp(GOBP:"apoptotic process")
PubMed Central:PMC3287608	act(p(HGNC:SLC25A21)) increases a(CHEBI:"reactive oxygen species")
PubMed Central:PMC3287608	act(p(HGNC:SLC25A21)) increases p(GFAM:Caspases)
PubMed Central:PMC3287608	act(p(HGNC:SLC25A21)) increases tloc(a(CHEBI:glycine), fromLoc(GOCC:cytoplasm), toLoc(GOCC:mitochondrion))
PubMed Central:PMC3287608	act(p(HGNC:SLC25A21)) increases tloc(a(CHEBI:"5-aminolevulinic acid"), fromLoc(GOCC:cytoplasm), toLoc(GOCC:mitochondrion))
PubMed Central:PMC3287608	p(HGNC:SLC25A21) positiveCorrelation path(MESH:D000544)
PubMed Central:PMC3287608	p(HGNC:SLC25A21) positiveCorrelation composite(a(CHEBI:"L-glutamate(1-)"), a(CHEBI:"amyloid-beta"))
pmid:22523685	complex(p(HGNC:APP, frag("672_713")), p(HGNC:PPID)) decreases act(a(MESH:D008928))
PubMed Central:PMC3287608	composite(a(CHEBI:"L-glutamate(1-)"), a(CHEBI:"amyloid-beta")) positiveCorrelation p(HGNC:SLC25A21)
pmid:17426120	g(HGNC:OGG1, var("c.796Cdel")) decreases act(p(HGNC:OGG1))
PubMed Central:PMC3287608	p(GFAM:Caspases) increases bp(GOBP:"apoptotic process")
pmid:22055193	act(p(HGNC:ATM)) increases act(p(HGNC:TP53))
pmid:24357806	p(HGNC:NLRP3) increases p(HGNC:IL1B)
pmid:24357806	p(HGNC:NLRP3) increases a(CHEBI:"reactive oxygen species")
pmid:23954639	p(HGNC:NOX4) increases act(p(HGNC:TP53))
pmid:16484331	p(HGNC:OGG1) orthologous p(RGD:Ogg1)
pmid:21845541	p(HGNC:OGG1) decreases p(HGNC:TNF)
pmid:21845541	p(HGNC:OGG1) increases bp(MESHPP:"Oxidative Stress")
pmid:17426120	p(HGNC:OGG1, var("p.Ala288Val")) association path(MESHD:"Alzheimer Disease")
pmid:17426120	p(HGNC:OGG1, var("p.Ala288Val")) decreases act(p(HGNC:OGG1))
pmid:17426120	p(HGNC:OGG1, var("p.Ala53Thr")) association path(MESHD:"Alzheimer Disease")
pmid:17426120	p(HGNC:OGG1, var("p.Ala53Thr")) decreases act(p(HGNC:OGG1))
pmid:16443152	act(p(HGNC:PLA2G1B)) increases a(CHEBI:"reactive oxygen species")
pmid:23954639	act(p(HGNC:PRKAA2)) decreases a(CHEBI:"reactive oxygen species")
pmid:17015226	p(HGNC:SLC1A2) association bp(GOBP:"glutamate homeostasis")
pmid:25018698	p(MGI:Map3k5) increases bp(GOBP:"neuron death")
pmid:25018698	p(MGI:Sod1, var("p.Gly93Ala")) increases act(p(MGI:Map3k5))
pmid:16484331	p(RGD:Ogg1) orthologous p(HGNC:OGG1)
pmid:16484331	act(p(RGD:Ogg1)) negativeCorrelation a(CHEBI:"8-hydroxy-2'-deoxyguanosine")
pmid:18718604	act(p(SFAM:"PRKC Family")) increases bp(MESHPP:"Oxidative Stress")
PubMed Central:PMC3287608	path(MESH:D000544) positiveCorrelation p(HGNC:SLC25A21)
pmid:22956607	path(MESHD:"Fuchs' Endothelial Dystrophy") positiveCorrelation bp(MESHPP:"Oxidative Stress")
pmid:21573099	a(CHEBI:"beta-carboline") decreases p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:17120162	a(CHEBI:isoprenaline) increases act(p(HGNC:PRKACA))
pmid:21707856	act(a(MESHC:"Protein Kinase C")) association p(HGNC:MAPT, pmod(Ph))
pmid:21297267	a(MESHC:"calyculin A") increases p(HGNC:MAPT, pmod(Ph, Ser, 198))
pmid:21297267	a(MESHC:"calyculin A") increases p(HGNC:MAPT, pmod(Ph, Ser, 199))
pmid:21297267	a(MESHC:"calyculin A") increases p(HGNC:MAPT, pmod(Ph, Ser, 202))
pmid:21297267	a(MESHC:"calyculin A") increases p(HGNC:MAPT, pmod(Ph, Ser, 396))
pmid:21297267	a(MESHC:"calyculin A") increases p(HGNC:MAPT, pmod(Ph, Ser, 404))
pmid:21297267	a(MESHC:"calyculin A") increases p(HGNC:MAPT, pmod(Ph, Thr, 205))
pmid:21297267	a(MESHC:"calyculin A") increases p(HGNC:MAPT, pmod(Ph, Thr, 231))
pmid:19519303	bp(GOBP:"JNK cascade") increases p(HGNC:MAPT, pmod(Ph))
pmid:21297267	bp(GOBP:"positive regulation of protein phosphatase type 2A activity") association a(CHEBI:berberine)
pmid:21666500	bp(GOBP:"regulation of cell cycle") negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:21666500	bp(GOBP:"regulation of cell cycle") association p(HGNC:RB1, pmod(Ph))
pmid:18675468	bp(GOBP:"regulation of microtubule cytoskeleton organization") association p(HGNC:MAPT)
pmid:12668899	bp(GOBP:"synapse maturation") association a(CHEBI:cholesterol)
pmid:22720189	bp(MESHPP:"Cell Physiological Phenomena") association m(HGNC:"MIR16-1")
pmid:22720189	bp(MESHPP:"Cell Physiological Phenomena") association m(HGNC:MIR132)
pmid:21367866	bp(PTS:"chaperone signaling pathway") association p(HGNC:MAPT)
pmid:19419557	complex(GOCC:"calcineurin complex") decreases p(HGNC:MAPT, pmod(Ph))
pmid:19228967	complex(p(FPLX:HSPA), p(HGNC:BAG2)) increases deg(p(HGNC:MAPT))
pmid:22496686	complex(p(HBP:"CDK5R1 p25"), p(HGNC:CDK5)) increases p(HGNC:MAPT, pmod(Ph))
pmid:22496686	complex(p(HBP:"CDK5R1 p25"), p(HGNC:CDK5)) decreases complex(a(GOCC:microtubule), p(HGNC:MAPT))
pmid:7695621	complex(p(HGNC:APOE), p(HGNC:MAPT)) association complex(GOCC:"neurofibrillary tangle")
pmid:22496686	complex(p(HGNC:APP), p(HGNC:GRB2), p(HGNC:SHC1)) increases act(p(SFAM:"MAPK Erk1/2 Family"))
pmid:19317853	complex(p(HGNC:BAG1), p(HGNC:HSPA8), p(HGNC:MAPT)) decreases deg(p(HGNC:MAPT))
pmid:17954934	p(HGNC:BAG1) decreases deg(p(HGNC:MAPT))
pmid:17954934	p(HGNC:BAG1) decreases deg(p(HGNC:MAPT))
pmid:19491104	complex(p(HGNC:KIF16B), p(HGNC:MAPK8IP1)) negativeCorrelation complex(p(HGNC:MAPK8IP1), p(HGNC:MAPT, pmod(Ph)))
pmid:19491104	complex(p(HGNC:MAPK8IP1), p(HGNC:MAPT, pmod(Ph))) negativeCorrelation complex(p(HGNC:KIF16B), p(HGNC:MAPK8IP1))
pmid:19491104	complex(p(HGNC:MAPK8IP1), p(HGNC:MAPT, pmod(Ph))) decreases complex(p(HGNC:KLC1), p(HGNC:MAPK8IP1))
pmid:12575378	complex(p(HGNC:MAPT), p(HGNC:PSEN1)) decreases p(HGNC:MAPT, pmod(Ph))
pmid:10840038	p(HGNC:YWHAZ) increases act(p(HGNC:PRKAR1A), ma(kin))
pmid:19419557	composite(p(HGNC:CAMK2A), p(HGNC:CAMK2B)) increases p(HGNC:MAPT, pmod(Ph))
pmid:11810404	p(HGNC:CAMK2B) increases p(HGNC:MAPT, pmod(Ph))
pmid:11810404	p(HGNC:CAMK2B) causesNoChange p(HGNC:MAPT, pmod(Ph))
pmid:22720189	m(HGNC:"MIR16-1") association p(HGNC:MAPT, pmod(Ph))
pmid:22720189	m(HGNC:"MIR16-1") association r(HGNC:MAPT)
pmid:22720189	m(HGNC:"MIR16-1") association bp(MESHPP:"Cell Survival")
pmid:22720189	m(HGNC:"MIR16-1") association bp(MESHPP:"Cell Physiological Phenomena")
pmid:20660113	m(HGNC:MIR15A) increases p(HGNC:MAPK3)
pmid:20660113	m(HGNC:MIR15A) negativeCorrelation path(MESHD:"Alzheimer Disease")
pmid:20067632	p(HGNC:AKAP13) increases p(HGNC:MAPT, pmod(Ph, Ser, 262))
pmid:20067632	p(HGNC:AKAP13) increases p(HGNC:MAPT, pmod(Ph, Ser, 356))
pmid:21367866	p(HGNC:CDC37) decreases deg(p(HGNC:MAPT))
pmid:21367866	p(HGNC:CDC37) decreases p(SFAM:"HSP90 Family")
pmid:8282104	act(p(HGNC:CDK2), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:22222439	act(p(HGNC:CRH)) association p(HGNC:MAPT, pmod(Ph))
pmid:16410745	act(p(HGNC:F2), ma(pep)) increases deg(p(HGNC:MAPT))
pmid:14999081	act(p(HGNC:FYN), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Tyr, 18))
pmid:17146290	p(HGNC:GRK2) association p(HGNC:MAPT, pmod(Ph))
pmid:17146290	p(HGNC:GRK2) association p(HGNC:MAPT, pmod(Ph))
pmid:15773910	p(HGNC:MAPT, pmod(Ph, Ser, 214)) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:22397366	p(HGNC:MAPT, var("misfolded")) increases bp(GOBP:"microglial cell activation")
pmid:19647741	p(HGNC:MAPT, var("p.Ser156Ala")) decreases complex(p(HGNC:MAPT), p(HGNC:YWHAZ))
pmid:19647741	p(HGNC:MAPT, var("p.Ser156Ala")) decreases complex(p(HGNC:MAPT), p(HGNC:YWHAZ))
pmid:19647741	p(HGNC:MAPT, var("p.Ser235Ala")) decreases complex(p(HGNC:MAPT), p(HGNC:YWHAZ))
pmid:19647741	p(HGNC:MAPT, var("p.Ser267Ala")) decreases complex(p(HGNC:MAPT), p(HGNC:YWHAZ))
pmid:17154549	p(HGNC:NPEPPS) association deg(p(HGNC:MAPT))
pmid:21320871	act(p(HGNC:NPEPPS), ma(pep)) increases deg(p(HGNC:MAPT))
pmid:11104762	act(p(HGNC:PKN1), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:21489990	act(p(HGNC:PPP1CA), ma(phos)) decreases p(HGNC:MAPT, pmod(Ph, Ser, 262))
pmid:21489990	p(HGNC:PPP1CA, pmod(Ph)) decreases act(p(HGNC:PPP1CA), ma(phos))
pmid:8529836	act(p(HGNC:PPP2CB), ma(phos)) decreases p(HGNC:MAPT, pmod(Ph))
pmid:11104762	p(HGNC:PPP3CA) decreases p(HGNC:MAPT, pmod(Ph, Ser, 320))
pmid:12435421	act(p(HGNC:PPP5C), ma(phos)) decreases p(HGNC:MAPT, pmod(Ph))
pmid:10840038	act(p(HGNC:PRKAR1A), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 262))
pmid:10840038	act(p(HGNC:PRKAR1A), ma(kin)) increases p(HGNC:MAPT, pmod(Ph, Ser, 356))
pmid:21666500	p(HGNC:RB1, pmod(Ph)) association p(HGNC:MAPT, pmod(Ph))
pmid:21666500	p(HGNC:RB1, pmod(Ph)) association bp(GOBP:"regulation of cell cycle")
pmid:20066010	act(p(HGNC:TP53INP2)) regulates deg(p(HGNC:APP))
pmid:20075608	act(p(HGNC:TPK1), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:9089387	act(p(HGNC:TPK1), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:20075608	act(p(HGNC:TPK1), ma(kin)) increases p(HGNC:PDHA1, pmod(Ph))
pmid:24808823	p(MGI:Ttbk1) increases p(GFAM:Tubulins, pmod(Ph))
pmid:24808823	p(MGI:Ttbk1) increases p(MGI:Mapt, pmod(Ph))
pmid:24808823	p(MGI:Ttbk1) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:24808823	p(MGI:Ttbk1) positiveCorrelation path(MESHD:"Alzheimer Disease")
pmid:24808823	p(MGI:Ttbk1) association p(MGI:Mapt)
pmid:24808823	p(MGI:Ttbk1) increases bp(GOBP:"neuron death")
pmid:24808823	p(MGI:Ttbk1) decreases bp(GOBP:"axon regeneration")
pmid:24808823	p(MGI:Ttbk1) decreases bp(GOBP:"axon regeneration")
pmid:24808823	p(MGI:Ttbk1) positiveCorrelation path(MESHD:Tauopathies)
pmid:24808823	p(MGI:Ttbk2) increases p(GFAM:Tubulins, pmod(Ph))
pmid:24808823	p(MGI:Ttbk2) increases p(MGI:Mapt, pmod(Ph))
pmid:24808823	p(MGI:Ttbk2) increases p(MGI:Mapt, pmod(Ph))
pmid:24808823	p(MGI:Ttbk2) association path(MESHD:"Spinocerebellar Ataxias")
pmid:24808823	p(MGI:Ttbk2) increases p(MGI:Mapt, pmod(Ph, Ser, 422))
pmid:24808823	p(MGI:Ttbk2) increases act(p(MGI:Cdk5))
pmid:3121601	act(p(SFAM:"CAMK Family"), ma(kin)) increases p(HGNC:MAPT, pmod(Ph))
pmid:21367866	p(SFAM:"HSP90 Family") increases deg(p(HGNC:MAPT))
pmid:15658002	path(DO:"progressive supranuclear palsy") association p(HGNC:MAPT, pmod(Ph))
pmid:15658002	path(HBP:"Argyrophilic Grain Disease") association p(HGNC:MAPT, pmod(Ph))
pmid:24884485	path(MESH:D060825) negativeCorrelation p(HGNC:MAPT)
pmid:24884485	path(MESH:D060825) negativeCorrelation p(HGNC:MAPT, pmod(Ph))
pmid:12428805	path(MESHD:"Frontotemporal Dementia") association p(HGNC:MAPT)
pmid:15658002	path(MESHD:"Niemann-Pick Diseases") association p(HGNC:MAPT, pmod(Ph))
pmid:24808823	path(MESHD:"Spinocerebellar Ataxias") association p(MGI:Ttbk2)
pmid:12428805	path(MESHD:"Supranuclear Palsy, Progressive") association p(HGNC:MAPT)
pmid:8129042	r(HGNC:MAPK1) negativeCorrelation complex(GOCC:"neurofibrillary tangle")
pmid:8129042	r(HGNC:MAPK1) negativeCorrelation p(HGNC:MAPT, pmod(Ph))

Curation Quality

Namespaces

Namespace References 26

This section lists all of the namespaces that are defined in the original BEL document.

Keyword	URL
ADO	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/alzheimer-disease-ontology/alzheimer-disease-ontology-1.0.2.belns
BRCO	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/brain-region-ontology/brain-region-ontology-1.0.0.belns
CHEBI	https://raw.githubusercontent.com/pharmacome/terminology/1b20f0637c395f8aa89c2e2e342d7b704062c242/external/chebi-names.belns
CTO	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/clinical-trial-ontology/clinical-trial-ontology-1.0.0.belns
DO	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/disease-ontology/disease-ontology-20170725.belns
ECCODE	https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/ec-code.belns
FPLX	https://raw.githubusercontent.com/sorgerlab/famplex/e8ae9926ff95266032cb74f77973c84939bffbeb/export/famplex.belns
GFAM	https://raw.githubusercontent.com/pharmacome/terminology/3f89d31906739fce9678d868b6a599a851aa7c00/external/hgnc.genefamily-names.belns
GO	https://raw.githubusercontent.com/pharmacome/terminology/1b20f0637c395f8aa89c2e2e342d7b704062c242/external/go.belns
GOBP	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/go-biological-process/go-biological-process-20170725.belns
GOCC	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/go-cellular-component/go-cellular-component-20170725.belns
HBP	https://raw.githubusercontent.com/pharmacome/terminology/570376e4c233483b667eab12a1f964950368282a/export/hbp-names.belns
HGNC	https://raw.githubusercontent.com/pharmacome/terminology/1b20f0637c395f8aa89c2e2e342d7b704062c242/external/hgnc-symbols.belns
HP	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/hp/hp-20171108.belns
INTERPRO	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/interpro/interpro-20170731.belns
MESH	https://raw.githubusercontent.com/pharmacome/terminology/1b20f0637c395f8aa89c2e2e342d7b704062c242/external/mesh.belns
MESHC	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/mesh-chemicals/mesh-chemicals-20170725.belns
MESHCS	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/mesh-cell-structures/mesh-cell-structures-20170511.belns
MESHD	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/mesh-diseases/mesh-diseases-20170725.belns
MESHPP	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/mesh-processes/mesh-processes-20170725.belns
MGI	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/mgi-mouse-genes/mgi-mouse-genes-20170725.belns
NIFT	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/imaging-ontology/imaging-ontology-1.0.6.belns
PTS	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/neurodegeneration-pathways/neurodegeneration-pathways-1.0.0.belns
RGD	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/rgd-rat-genes/rgd-rat-genes-20170725.belns
SCOMP	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/selventa-named-complexes/selventa-named-complexes-20170725.belns
SFAM	https://arty.scai.fraunhofer.de/artifactory/bel/namespace/selventa-protein-families/selventa-protein-families-20170725.belns

Annotations

Annotation References 11

This section lists all of the annotations that are defined in the original BEL document.

Keyword	URL
Anatomy	https://arty.scai.fraunhofer.de/artifactory/bel/annotation/anatomy/anatomy-20170511.belanno
Cell	https://arty.scai.fraunhofer.de/artifactory/bel/annotation/cell/cell-20170511.belanno
CellLine	https://arty.scai.fraunhofer.de/artifactory/bel/annotation/cell-line/cell-line-20170511.belanno
CellStructure	https://arty.scai.fraunhofer.de/artifactory/bel/annotation/cell-structure/cell-structure-20170511.belanno
Confidence	https://arty.scai.fraunhofer.de/artifactory/bel/annotation/confidence/confidence-1.0.0.belanno
Disease	https://arty.scai.fraunhofer.de/artifactory/bel/annotation/disease/disease-20170511.belanno
Gender	https://arty.scai.fraunhofer.de/artifactory/bel/annotation/gender/gender-1.0.0.belanno
MeSHAnatomy	https://arty.scai.fraunhofer.de/artifactory/bel/annotation/mesh-anatomy/mesh-anatomy-20170511.belanno
MeSHDisease	https://arty.scai.fraunhofer.de/artifactory/bel/annotation/mesh-diseases/mesh-diseases-20170511.belanno
Subgraph	https://arty.scai.fraunhofer.de/artifactory/bel/annotation/neurommsig/neurommsig-1.0.3.belanno
TextLocation	https://arty.scai.fraunhofer.de/artifactory/bel/annotation/text-location/text-location-1.0.1.belanno

Locally Defined Annotations 14

The source BEL document contained annotations defined as a list. Click each link to export the list definition as a BELANNO file that can hosted externally to promote re-usability and interoperability. After, you can replace the list definition in the source BEL with a SET ANNOTATION X AS URL "Y" definition.

Condition
Developmental_Phase__of_patient
DiseaseState
Duration_of_Chemical_Exposure
Encode_Feature_Types
Experimental_Group
FDASTATUS
KnockoutMice
NIFT
Patient
Published
Race
Transcriptionally_active_region
UserdefinedCellLine